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| 1 | Functional properties of protein fractions of channel catfish (Ictalurus punctatus) and their effects in an emulsion system显示文摘 | YIN Huaixia WAN Yuting PU Jianing | | 0，，03： | 1 |
| 2 | Rheological and functional properties of catfish skin protein hydroly- sates显示文摘 | YIN Huaixia PU Jianing WAN Yuting | 2010 | Journal of Food Science2010，75，1： | 1 |
| 3 | Improved spatiotemporal resolution of anti-scattering super-resolution label-free microscopy via synthetic wave 3D metalens imaging显示文摘Super-resolution(SR)microscopy has dramatically enhanced our understanding of biological processes.However,scattering media in thick specimens severely limits the spatial resolution,often rendering the images unclear or indistinguishable.Additionally,live-cell imaging faces challenges in achieving high temporal resolution for fast-moving subcellular structures.Here,we present the principles of a synthetic wave microscopy(SWM)to extract three-dimensional information from thick unlabeled specimens,where photobleaching and phototoxicity are avoided.SWM exploits multiple-wave interferometry to reveal the specimen’s phase information in the area of interest,which is not affected by the scattering media in the optical path.SWM achieves~0.42λ/NA resolution at an imaging speed of up to 106 pixels/s.SWM proves better temporal resolution and sensitivity than the most conventional microscopes currently available while maintaining exceptional SR and anti-scattering capabilities.Penetrating through the scattering media is challenging for conventional imaging techniques.Remarkably,SWM retains its efficacy even in conditions of low signal-to-noise ratios.It facilitates the visualization of dynamic subcellular structures in live cells,encompassing tubular endoplasmic reticulum(ER),lipid droplets,mitochondria,and lysosomes. | Yuting Xiao Lianwei Chen Mingbo Pu Mingfeng Xu Qi Zhang Yinghui Guo Tianqu Chen Xiangang Luo | 2023 | Opto-Electronic Science2023，2，11： | 1 |
| 4 | Preparation and Properties of Guiqi Polysaccharides/Chitosan/Alginate Composite Hydrogel Microspheres显示文摘A series of the Guiqi polysaccharides/chitosan/alginate composite hydrogel microspheres(GPcM)with different particle sizes were prepared with Guiqi polysaccharides(GP),chitosan(CS)and sodium alginate(Alg).The optimum preparation process was also determined by single factor and orthogonal experiment analysis.The GPcM were characterized by fourier transform infrared spectroscopy(FT-IR),scanning electron microscope(SEM),drug loading efficiency test(LE),encapsulation efficiency test(EE)and in vitro release study.The results showed that the Guiqi polysaccharides chitosan hydrogel(GPCH)and sodium alginate hydrogel(SAH)formed a crossover system in GPcM.The GPcM have a uniform particle size ranging from 395.1μm to 841.5μm.The drug loading efficiency and encapsulation efficiency of the GPcM were 56.3%and 72.6%,respectively.The bovine serum albumin(BSA)loaded in the GPcM released slowly within 180 h.The results suggested that the GPcM may have potential application value in drug sustained and controlled release system. | Xiaoliang Zhao Yuting Wang Xiuying Pu Jianzhong Ma Feifan Leng Yonggang Wang Yanling Wang Shuhong Yang Fen Ran Weijie Zhang | 2019 | Journal of Renewable Materials2019，7，12： | 0 |
| 5 | Clinical efficacy of Buzhong Yiqi decoction(补中益气汤)in the treatment of hospital-acquired pneumonia with multi-drug resistant bacteria:a prospective,randomized,multicenter controlled trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of Buzhong Yiqi decoction(补中益气汤,BZYQ)in the treatment of hospital-acquired pneumonia(HAP)with multi-drug-resistant bacteria(MDRB).METHODS:This 28-day study was conducted at 5 clinical centers in Shanghai.The eligible patients were randomly assigned(1∶1)into the intervention group(BZYQ plus conventional Western Medicine therapy)and control group(conventional Western Medicine therapy).The primary outcomes were the clinical response,clinical pulmonary infection score(CPIS),and microbiologic response.The secondary outcomes were the 28-day allcause mortality(ACM),Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ)score,ventilator weaning rate,length of mechanical ventilation(MV),length of hospital stay,and changes of infection indicators.RESULTS:Altogether 83 subjects in the intervention group and 85 subjects in the control group were analyzed.The clinical success rate(48.2%)and the pathogen eradication rate(59.0%)of the intervention group were all better than those of the control group(32.9%and 38.9%,respectively)with statistically significant differences(P<0.05).The CPIS score of the intervention group(8.9±1.7)was lower than that of the control group(9.6±2.5)(P<0.05).The length of MV in the intervention group[(13.7±6.4)d]was significantly shorter than that of the control group[(17.2±7.2)d](P<0.05).The 28-day ACM of the intervention group(13.33%)was lower than that of the control group(21.2%)with no statistically significant difference(P>0.05).The differences between two groups in ventilator weaning rate,length of hospital stay,and APACHEⅡscore were not statistically significant(P>0.05).The intervention group displayed decreases in white blood cell count,C-reactive protein,neutrophil percentage,and procalcitonin at day 28 compared with baseline(P<0.05).No serious adverse events occurred in either group during the 28-day follow-up.CONCLUSION:BZYQ may be an effective therapeutic option for the management of HAP with MDRB. | XU Xiangru ZHOU Yi CHEN Gang LEI Ming ZHANG Wen WU Xinxin PU Yuting CHEN Caiyu SUN Yuting ZHOU Shuang FANG Bangjiang | 2023 | Journal of Traditional Chinese Medicine2023，43，5： | 0 |
| 6 | Graphene foam/hydrogel scaffolds for regeneration of peripheral nerve using ADSCs in a diabetic mouse model显示文摘The functional recovery of peripheral nerve injury(PNI)is unsatisfactory,whereas diabetes mellitus(DM)and its related complications further attenuate the restoration of diabetic PNI(DPNI).Adipose-derived stem cells(ADSCs)are promising candidates for treatment of DPNI due to their abundant source,excellent differentiation and paracrine ability.Our results showed that ADSCs remarkably enhanced the proliferation and migration of Schwann cells and endothelial cells,and tube formation.Mechanistically,ADSCs could regulate Nrf2/HO-1,NF-κB and PI3K/AKT/mTOR signaling pathways,showing multiple functions in reducing oxidative stress and inflammation,and regulating cell metabolism,growth,survival,proliferation,angiogenesis,differentiation of Schwann cell and myelin formation.In current study,novel graphene foam(GF)/hydrogel-based scaffold was developed to deliver ADSCs for treatment of DPNI.GF/hydrogel scaffold exhibited excellent mechanical strength,suitable porous network,superior electrical conductivity,and good biocompatibility.In vitro results revealed that GF/hydrogel scaffold could obviously accelerate proliferation of Schwann cells.Moreover,in vivo experiments demonstrated that ADSCs-loaded GF/hydrogel scaffold significantly promoted the recovery of DPNI and inhibited the atrophy of targeted muscles,thus providing a novel and attractive therapeutic approach for DPNI patients. | Qun Huang Yuting Cai Xinrui Yang Weimin Li Hongji Pu Zhenjing Liu Hongwei Liu Mohsen Tamtaji Feng Xu Liyuan Sheng Tae-Hyung Kim Shiqing Zhao Dazhi Sun Jinbao Qin Zhengtang Luo Xinwu Lu | 2022 | Nano Research2022，15，4： | 0 |
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