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| 1 | Fault Systems and Their Mechanisms of the Formation and Distribution of the Tarim Basin,NW China显示文摘This article aims to analyze the main controlling factors of development,distribution and evolution of the fault systems in the Tarim Basin.Based on the seismic profile interpretation,comprehensive analysis of the drilling and geologic data,six fault systems maybe recognized in the Tarim Basin,they are the foreland fault system of the South Tianshan Mountain,the northern Tarim uplift fault system,North Tarim depression fault system,central fault system,Southwest Tarim fault system,and Southeast Tarim fault system.It is indicated that the main differences exist at the development,evolution and distribution of the fault systems in the Tarim Basin.The sub-fault systems can be recognized according to the differences of the fault development and distribution in the interior of the fault system.It is characterized that the multi-level differential development and distribution of the fault systems exist in the Tarim Basin.The fault belt developed in the Paleozoic strata mainly distribute at the paleo-uplift and paleo-slope in the interior of the Tarim Basin,and the fault belt occurred in the Meso–Cenozoic beds mainly develop at the peripheral foreland depressions.Zonal and segment differential development and distribution of the fault systems also exist in the Tarim Basin.The formation and distribution of the Tarim fault systems is of complex controlling mechanisms.Poly-phase structural movement and tectonic transition controls the multi-phase differential development and distribution of the fault systems in the Tarim Basin.Multi-level differential development and distribution is controlled by multi-level detachment belt and regional unconformities.Zonal and segment differential development and distribution of the Tarim fault systems maybe controlled by pre-existed basement structural texture.The major direction of the fault systems in the Tarim Basin is controlled by the later stage basin-mountain coupling. | Liangjie Tang Taizhu Huang Haijun Qiu Guimei Wan Meng Li Yong Yang Daqing Xie Gang Chen | 2014 | Journal of Earth Science2014，25，1： | 6 |
| 2 | Dietary oregano essential oil supplementation improves intestinal functions and alters gut microbiota in latephase laying hens显示文摘Background:Dietary essential oil(EO)supplementation can exert favorable effects on gut health in broilers.However,it is unknown whether EO could improve intestinal functions,consequently beneficial for egg performance and quality in late-phase laying hens.This study was aimed to investigate the potential effects of EO on production performance,egg quality,intestinal health and ileal microbiota of hens in the late phase of production.A total of 28860-week-old Hy-line Brown laying hens were randomly divided into 4 groups and fed a basal diet(control)or basal diets supplemented with oregano EO at 100,200 and 400 mg/kg(EO100,EO200 and EO400).Results:Dietary EO supplementation resulted in a quadratic decrease(P<0.05)in feed conversion ratio with lower(P<0.05)feed conversion ratio in EO200 group than the control during weeks 9–12 and 1–12 of the trial.Compared to the control,EO addition resulted in higher(P<0.05)eggshell thickness at the end of week.4,8 and 12 and higher(P<0.05)chymotrypsin activity.There was a quadratic elevation(P<0.05)in ileal chymotrypsin and lipase activity,along with a linear increase in villus height to crypt depth ratio.Quadratic declines(P<0.05)in mRNA expression of IL-1β,TNF-α,IFN-γ and TLR-4,concurrent with a linear and quadratic increase(P<0.05)in ZO-1 expression were identified in the ileum with EO addition.These favorable effects were maximized at medium dosage(200 mg/kg)of EO addition and intestinal microbial composition in the control and EO200 groups were assessed.Dietary EO addition increased(P<0.05)the abundances of Burkholderiales,Actinobacteria,Bifidobacteriales,Enterococcaceae and Bacillaceae,whereas decreased Shigella abundance in the ileum.Conclusions:Dietary EO addition could enhance digestive enzyme activity,improve gut morphology,epithelial barrier functions and modulate mucosal immune status by altering microbial composition,thus favoring feed efficiency and eggshell quality of late-phase laying hens. | Jia Feng Mingyuan Lu Jing Wang Haijun Zhang Kai Qiu Guanghai Qi Shugeng Wu | 2022 | Journal of Animal Science and Biotechnology2022，13，1： | 6 |
| 3 | ZmSRL5 is involved in drought tolerance by maintaining cuticular wax structure in maize显示文摘Cuticular wax is a natural barrier on terrestrial plant organs,which protects plants from damages caused by a variety of stresses.Here,we report the identification and functional characterization of a cuticular-wax-related gene,Zea mays L.SEMI-ROLLED LEAF 5(ZmSRL5).The loss-of-function mutant srl5,which was created by a 3,745 bp in-sertion in the first intron that led to the premature tran-script,exhibited abnormal wax crystal morphology and distribution,which,in turn,caused the pleiotropic pheno-types including increased chlorophyll leaching and water loss rate,decreased leaf temperature,sensitivity to drought,as well as semi-rolled mature leaves.However,total wax amounts showed no significant difference between wild type and semi-rolled leaf5(srl5)mutant.The phenotype of srl5 was confirmed through the generation of two allelic mutants using CRISPR/Cas9.ZmSRL5 encodes a CASPARIAN-STRIP-MEMBRANE-DOMAIN-LIKE(CASPL)protein located in plasma membrane,and highly expressed in developing leaves.Further analysis showed that the expressions of the most wax related genes were not affected or slightly al-tered in srl5.This study,thus,primarily uncovers that ZmSRL5 is required for the structure formation of the cu-ticular wax and could increase the drought tolerance by maintaining the proper cuticular wax structure in maize. | Zhenyuan Pan Min Liu Hailiang Zhao Zengdong Tan Kun Liang Qin Sun Dianming Gong Haijun He Wenqi Zhou Fazhan Qiu | 2020 | Journal of Integrative Plant Biology2020，62，12： | 5 |
| 4 | Oxidative depolymerization of lignin improved by enzymolysis pretreatment with laccase显示文摘A new lignin depolymerization approach for improving the yield of aromatic monomers(YAM) by enzymolysis pretreatment was investigated, in which lignin was pretreated with laccase followed by oxidative depolymerization. It was found that lignin depolymeirzation was enhanced significantly by enzymolysis. The oxidative depolymerization contributed to 21.37% of YAM after the enzymolysis pretreatment,whereas the conventional oxidative depolymerization only gave 14.10% of YAM. The addition of ethanol in enzymatic pretreatment process improved the efficiency of enzymolysis, which effectively improved the solubility of pretreated lignin and depolymerization degree(DD) of lignin. The enzymolysis pretreatment increased the content of syringyl(S) style aromatic monomers, which hindered the recondensation among polymerized products. As lignin has low solubility in acidic aqueous solution, ethanol was added into enzymolysis system to improve the efficiency. However, the enzymolysis of lignin should be carried out for a limited period of time to prevent the inactivation of laccase. | Yuan Zhu Xinping Ouyang Ying Zhao Linfeng Jiang Haijun Guo Xueqing Qiu | 2018 | Journal of Energy Chemistry2018，27，3： | 4 |
| 5 | Salt-related structure and deformation mechanism of the Middle-Lower Cambrian in the middle-west parts of the Central Uplift and adjacent areas of the Tarim Basin显示文摘The salt beds of the Middle-Lower Cambrian are widespread in the middle-west parts of the Central Uplift and adjacent areas, the Tarim Basin. This paper presents the results of seismic interpretation and drilling data analysis, which discovered that the salt beds were formed in an old geologic age, deeply buried, with relatively small scaled flowing and gathering and uneven distribution. As the regional detachment layers, the salt sequences considerably control the structural deformation of the up-salt Paleozoic, forming a series of hydrocarbon traps. In due course, the salt beds of the Middle-Lower Cambrian provide excellent cap rocks and trap conditions; thus the value of exploring hydrocabon reservoir in the target strata of the sub-salt Sinian- Cambrian is greatly increased. Research has shown that the salt-related structures of the Middle-Lower Cambrian in the area mainly exist in the form of salt pillow, salt roller, up-salt anticline, salt diapir, assemblage of the salt arch and up-salt fault-block, assemblage of basement fault and salt anticline, assemblage of the basement fault-block and salt dome, assemblage of salt detachment and fault-related fold, and assemblage of basement fault-block, salt arch and up-salt imbricated thrusts. The evolution and deformation mechanisms of the salt-related structures are controlled largely by basement faulting, compressional shortening, plastic flowing and gathering, superstratum gravitation, and up-salt faulting and detaching. They are distributed in rows or belts along basement faults or fault block belts. | TANG LiangJie HUANG TaiZhu QIU HaiJun QI LiXin YANG Yong XIE DaQing YU YiXin ZHAO Zhao CHEN ShuPing | 2012 | Science China Earth Sciences2012，55，7： | 3 |
| 6 | Distribution Features of the Nanhua-Sinian Rifts and their Significance to Hydrocarbon Accumulation in the Tarim Basin显示文摘On the basis of reprocessing 34 new two-dimensional spliced long sections(20,191 km) in the Tarim Basin, the deep structure features of the Tarim Basin were analyzed through interpreting 30,451 km of two-dimensional seismic data and compiling basic maps. Seismic interpretation and geological analysis conclude that the Nanhua-Sinian strata are a set of rift-depression depositional systems according to their tectonic and depositional features. The rift valley formed in the Nanhua Period, and the transformation became weaker during the late Sinian Period, which eventually turned into depression. From bottom to top, the deposited strata include mafic igneous, tillite, mudstone, and dolomite. Three major depocenters developed inside this basin during the rift stage and are distributed in the eastern Tarim Basin, the Awati area, and the southwestern Tarim Basin. Among them, the rift in the eastern Tarim Basin strikes in the near east-west direction on the plane and coincides with the aeromagnetic anomaly belt. This represents a strong magnetic zone formed by upwelling basic volcanic rock along high, steep normal faults of the Nanhua Period. Controlled by the tectonic background, two types of sedimentary systems were developed in the rift stage and depression stage, showing two types of sequence features in the Sinian depositional stage. The Nanhua System appears as a wedge-shaped formation, with its bottom in unconformable contact with the base. The rifting event has a strong influence on the current tectonic units in the Tarim Basin, and affects the distribution of source rock in the Yuertus Formation and reservoir beds in the Xiaoerbulake Formation in Lower Cambrian, as well as the gypseous cap rock in Middle Cambrian. The distribution features of the rifts have important and realistic significance for determining the direction of oil and gas exploration in the deep strata of the Tarim Basin. Comprehensive analysis suggests that the Tazhong region is the most favorable zone, and the Kalpin-Bachu region is the optimal potential zone for exploring sub-salt oil and gas in deep Cambrian strata. | BAI Zhongkai CHENG Minghua CHEN Cheng HUO Junzhou ZHANG Junfeng ZHOU Xingui GAO Yongjin ZHAO Bo QIU Haijun HAN Miao YANG Youxing SUN Zhichao MIAO Miaoqing ZHANG Jinhu LI Qingyao | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 3 |
| 7 | Dietary organic acids ameliorate high stocking density stress-induced intestinal inflammation through the restoration of intestinal microbiota in broilers显示文摘Background:High stocking density(HSD)stress has detrimental effects on growth performance,intestinal barrier function,and intestinal microbiota in intensive animal production.Organic acids(OA)are widely used as feed addi-tives for their ability to improve growth performance and intestinal health in poultry.However,whether dietary OA can ameliorate HSD stress-induced impaired intestinal barrier in broilers remains elusive.In this study,a total of 528 one-day-old male Arbor Acres broilers were randomly allocated into 3 treatments with 12 replicates per treatment including 10 birds for normal stocking density and 17 birds for HSD.The dietary treatments were as follows:1)Normal stocking density+basal diet;2)HSD+basal diets;3)HSD+OA.Results:HSD stress can induce increased levels of serum corticosterone,lipopolysaccharides,interleukin-1β,tumor necrosis factor-α,and down-regulated mRNA expression of ZO-1,resulting in compromised growth performance of broilers(P<0.05).Dietary OA could significantly reduce levels of serum corticosterone,lipopolysaccharides,interleukin-1β,and tumor necrosis factor-α,which were accompanied by up-regulated interleukin-10,mRNA expres-sion of ZO-1,and growth performance(P<0.05).Moreover,OA could down-regulate the mRNA expression of TLR4 and MyD88 to inhibit the NF-κB signaling pathway(P<0.05).Additionally,HSD stress significantly decreased the abundance of Bacteroidetes and disturbed the balance of microbial ecosystems,whereas OA significantly increased the abundance of Bacteroidetes and restored the disordered gut microbiota by reducing competitive and exploita-tive interactions in microbial communities(P<0.05).Meanwhile,OA significantly increased the content of acetic and butyric acids,which showed significant correlations with intestinal inflammation indicators(P<0.05).Conclusions:Dietary OA ameliorated intestinal inflammation and growth performance of broilers through restor-ing the disordered gut microbial compositions and interactions induced by HSD and elevating short-chain fatty acid production to inhibit the TLR4/NF-κB signaling pathway.These findings demonstrated the critical role of intestinal microbiota in mediating the HSD-induced inflammatory responses,contributing to exploring nutritional strategies to alleviate HSD-induced stress in animals. | Dong Dai Guanghai Qi Jing Wang Haijun Zhang Kai Qiu Yanming Han Yuanyuan Wu Shugeng Wu | 2023 | Journal of Animal Science and Biotechnology2023，14，2： | 1 |
| 8 | CFD study on mean flow engine for wind power ex ploitation 显示文摘 | Yan Yu Da-ming Sun Ke Wu Ya Xu Haijun Chen Xue-jun Zhang Li-min Qiu | 2011 | Energy Conversion and Management2011，52，6： | 1 |
| 9 | Exhumation structure and mechanism of the Sulu ultrahigh-pressure metamorphic belt central China显示文摘 | Xu Zhiqin Zhang Zemin Liu Fulai Yang Jingsui Li Haibing Yang Tiannan Qiu Haijun Li Tianfu Meng Fanchong Chen Shizhong Tang Zemin and Chen Fangyuan | | ACTA GEOLOGICA SINICA(CHINESE EDITION)0，，： | 1 |
| 10 | Uterine inflammation status modulates eggshell mineralization via calcium transport and matrix protein synthesis in laying hens显示文摘This study explored the effects of uterine inflammation on eggshell mineralization,ultrastructure and mechanical properties in laying hens modified by a lipopolysaccharide(LPS)challenge or dietary essential oil(EO)addition.In trial 1,a total of 72 Hy-line Brown layers at 36 wk of age were randomly assigned to 3 treatment groups(n=8),where they were intravenously injected with phosphate buffered saline,LPS at 1 mg/kg body weight,or LPS 3 times at 24-h intervals.In trial 2,a total of 288 Hy-line Brown layers at 60 wk of age were randomly divided into 4 groups(n=8),where they were fed basal diets supplemented with EO at 0,50,100 and 200 mg/kg for 12 wk.A uterine inflammation model was constructed with LPS treatment,indicated by the elevated expression of IL-1β and TNF-α(P<0.05)and lymphocyte infiltration.Uterine inflammation caused remarkable decreases in eggshell thickness and mechanical properties with structure deteriorations(P<0.05).Uterine inflammation stimulated the expression of matrix proteins ovotransferrin(TF)and ovalbumin(OVAL),while depressing the mRNA levels of calbindin-1(CALB1)and osteopontin in uterine mucosa(P<0.05).In contrast,EO addition alleviated uterine inflammation,evidenced by depressed levels of IL-1b and IL-6(P<0.05).There was a significant elevation in shell thickness and breaking strength following EO intervention(P<0.05),and these effects were maximized at addition of 100 mg/kg.Further,EO improved shell ultrastructure including more early fusion,less type B mammillae,and increased effective thickness(P<0.05).The alleviated inflammation decreased the expression of OVAL and TF,whereas ion transport genes like CALB1 and solute carrier family 26 member 9 were upregulated(P<0.05).Our findings suggest that inflam-matory status can impact uterine functions in calcium transport and the synthesis of matrix proteins especially such as OVAL and TF,which in turn modulates calcium precipitation and ultrastructure for-mation,thereby determining eggshell mechanical properties.These findings provide a novel insight into the uterine inflammation-mediated modifications of eggshell quality. | Jia Feng Mingyuan Lu Lingling Ma Haijun Zhang Shugeng Wu Kai Qiu Yuna Min Guanghai Qi Jing Wang | 2023 | Animal Nutrition2023，，2： | 1 |
| 11 | Identification and characterization of selenoprotein K:An antioxidant in cardiomyocytes显示文摘 | Cailing Lu Feichan Qiu Haijun Zhou | 2006 | FEBS Lett2006，580，： | 1 |
| 12 | CO 2 laser scan- ning repair fused silica surface defects显示文摘 | Jiang Yong He Shaobo Yuan Xiaodong Wang Haijun Li- ao Wei Lv Haibing Liu Chunming Xiang Xia Qiu Rong Yang Yongjia Zheng Wanguo the experimental researches and numerical simulations of Zu Xiaotao | 2014 | Journal of phys- ics2014，，06： | 1 |
| 13 | Geochemical Characteristics and Gas-to-Gas Correlation of Two Leakage-type Gas Hydrate Accumulations in the Western Qiongdongnan Basin, South China Sea显示文摘In recent years,a series of highly saturated leakage-type gas hydrates have been discovered in the western Qiongdongnan Basin(QDNB),South China Sea.Based on the molecular compositional and isotopic characteristics of the gas samples relevant to the gas hydrates collected from the two leakage-type gas hydrate accumulations in the GMGS5 and GMGS6 drilling zones,a detailed geochemical gas-to-gas correlation was conducted in this study,in order to further understand the geochemical characteristics and possible hydrocarbon sources of these gas hydrates.The natural gas relevant to the gas hydrates in the GMGS5 block is characterized by wet gas(67.96%<%C_(1)<98.58%,C_(1)/C_(1+)<0.9)and significant molecular and carbon isotope fractionation within the depth profile,whereas the gas samples from the GMGS6 block exhibit the characteristics of dry gas(99.25%<%C_(1)<99.81%,C_(1)/C_(1+)>0.9)and lack molecular and carbon isotope fractionation.Approximately 40%‒60%of the methane within the gas hydrate is of microbial origin,while the C^(2+)gas components are typical coal-type gas that are derived from thermogenic source rocks or deeply-buried natural gas fields.In addition,typical in situ primary microbial methane(−80.6‰<δ^(13)C-C_(1)<−67.7‰)was discovered in well W b,which was applied to estimate the contribution of the microbial gas to the gas hydrates.The gas-to-gas correlation results show that the hydrate gases within the two leakage-type gas hydrate accumulations in the GMGS5 and GMGS6 blocks are geochemically different,suggesting that they may have been derived from different source kitchens.Our results further indicate that the deeply-buried thermogenic gas significantly contributed to the shallowly-buried gas hydrates in the western QDNB and multiple effective thermogenic source kitchens provided the hydrocarbon gas in the gas hydrate accumulations. | LAI Hongfei QIU Haijun LIANG Jinqiang KUANG Zenggui FANG Yunxin REN Jinfeng LU Jing’an | 2022 | Acta Geologica Sinica(English Edition)2022，96，2： | 1 |
| 14 | Numerical simulation of fluid flow and alloy melting in RH process for electrical steels显示文摘Based on the Eulerian-Lagrangian approach,a mathematical model was established to describe the gas-liquid flow behavior in the Ruhrstahl-Heraeus(RH)degasser.The momentum source and the turbulent kinetic energy source due to the motion of gas bubbles were considered for the liquid flow.The effect of the expansion of gas bubbles on the liquid velocity,recirculation rate,and mixing time was quantitatively evaluated.After the fluid flow reached the steady state,the melting and mixing processes of aluminum alloys in the RH degasser were also investigated.The results indicate that the expansion of gas bubbles has a significant infuence on the recirculation rate and the mixing time in the RH process.Increasing the superheat of liquid steel and decreasing the initial diameter of alloy particles are beneficial to promote the melting and mixing of alloy particles.Due to the existence of solidified steel shells,the maximum diameter of the alloy particle is about 1.5 times its initial diameter. | Haijun Wang Rui Xu Hai-tao Ling Wei Zhong Li-zhong Chang Sheng-tao Qiu | 2022 | Journal of Iron and Steel Research(International)2022，29，9： | 0 |
| 15 | Paleo-redox conditions across the Permian-Triassic boundary in shallow carbonate platform of the Nanpanjiang Basin, South China显示文摘Ocean anoxia has been widely implicated in the Permian-Triassic extinction.However,the duration and distribution of the ocean anoxia remains controversial.In this study,the detailed redox changes across the Permian-Triassic boundary(PTB)in the shallow platform interior at Great Bank of Guizhou(GBG)has been reconstructed based on the high-resolution microfossil composition and multiple paleo-redox proxies.The shallow platform is characterized by low sulfur(total sulfur(TS)and pyrite sulfur(Spy))concentrations,low Spy/TOC ratios,and low DOP values before the mass extinction,representing oxic conditions well.Following the mass extinction,the shift of multiple geochemical proxies,including high Spy/TOC ratios and DOP values,indicates dysoxic-anoxic conditions in shallow ocean.Furthermore,we reconstruct the transition of the redox conditions of Nanpanjiang Basin:the intense volcanic eruptions,which release huge CO2 and SO2 before the mass extinction,provoke the temperature rising and the collapse of terrestrial ecosystem.As a result,the increased weathering influx causes the carbon isotopic negative excursion and the expansion of the ocean oxygen minimum zone(OMZ).When the OMZ expanded into the photic zone,the episodic H2S release events enhance the pyrite burial at Dajiang section.Thus,intense volcanic eruptions,temperature increase,and oceanic hypoxia together lead to the PTB extinction.Recent studies show high temperature might be the key mechanism of the PTB extinction.In addition,this study confirms that the microbialites were formed in the dysoxicanoxic shallow water. | SONG HuYue TONG JinNan TIAN Li SONG HaiJun QIU HaiOu ZHU YuanYuan Thomas ALGEO | 2014 | Science China Earth Sciences2014，57，5： | 0 |
| 16 | A review on GaN HEMTs:nonlinear mechanisms and improvement methods显示文摘The GaN HEMT is a potential candidate for RF applications due to the high frequency and large power handling capability.To ensure the quality of the communication signal,linearity is a key parameter during the system design.However,the GaN HEMT usually suffers from the nonlinearity problems induced by the nonlinear parasitic capacitance,transconductance,channel transconductance etc.Among them,the transconductance reduction is the main contributor for the nonlinearity and is mostly attributed to the scattering effect,the increasing resistance of access region,the self-heating effect and the trapping effects.Based on the mechanisms,device-level improvement methods of transconductance including the trapping suppression,the nanowire channel,the graded channel,the double channel,the transconductance compensation and the new material structures have been proposed recently.The features of each method are reviewed and compared to provide an overview perspective on the linearity of the GaN HEMT at the device level. | Chenglin Du Ran Ye Xiaolong Cai Xiangyang Duan Haijun Liu Yu Zhang Gang Qiu Minhan Mi | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 17 | Genomic information of children with malignant brain tumors for the prediction of length of hospitalization显示文摘Dear Editor:Central nervous system tumors in the brain or spine are the most common solid tumors in children,which accounts for about 25%of cancers in children younger than 15 years of age,and are the most common cause of cancer deaths in children[1].The 5-year survival rate for central nervous system neoplasms has increased dramatically to 74%for patients under 18 years old(97%for benign/borderline malignant tumors)in 2022,compared to 20%in the 1970s[1].Without cure treatments and specific medications for many brain cancers,the dramatic increase of survival rate is largely due to improved hospital care and availability of clinical resources.The length of hospitalization of pediatric patients with brain cancer is an important indicator of prognosis as it reflects the required medical effort needed to care for these patients.The length of hospitalization is also critical for the healthcare system as hospital admission is a part of the care trajectory of the respective patients,related to the cost of medical care[2,3]. | Yichuan Liu Hui-Qi Qu Xiao Chang Frank D Mentch Haijun Qiu Kenny Nguyen Xiang Wang Amir Hossein Saeidian Deborah Watson Joseph Glessner Hakon Hakonarson | 2023 | Cancer Communications2023，43，11： | 0 |
| 18 | Symplectic perturbation series methodology for non-conservative linear Hamiltonian system with damping显示文摘In this paper,the symplectic perturbation series methodology of the non-conservative linear Hamiltonian system is presented for the structural dynamic response with damping.Firstly,the linear Hamiltonian system is briefly introduced and its conservation law is proved based on the properties of the exterior products.Then the symplectic perturbation series methodology is proposed to deal with the non-conservative linear Hamiltonian system and its conservation law is further proved.The structural dynamic response problem with eternal load and damping is transformed as the non-conservative linear Hamiltonian system and the symplectic difference schemes for the non-conservative linear Hamiltonian system are established.The applicability and validity of the proposed method are demonstrated by three engineering examples.The results demonstrate that the presented methodology is better than the traditional Runge–Kutta algorithm in the prediction of long-time structural dynamic response under the same time step. | Zhiping Qiu Haijun Xia | 2021 | Acta Mechanica Sinica2021，37，6： | 0 |
| 19 | A Patient-Specific Computational Fluid Dynamic Model of Middle Cerebral Artery Aneurysm Before and One Year After Surgery显示文摘Computational fluid dynamics(CFD)has been widely used for studying intracranial aneurysm hemodynamics,while its use for guiding clinical strategy is still in development.In this study,CFD simulations helped inform treatment decision for a middle cerebral artery(MCA)aneurysm case was investigated.A patient with a 10.4×9.8 mm aneurysm attached with a small aneurysm at the edge of the trifurcation in the left MCA was included in this study.For removing the MCA aneurysm,two scenarios were considered:Plan-A involved clipping the small aneurysm and Plan-B involved clipping the whole aneurysm.A suitable treatment plan was decided by comparing the clinical measurements and CFD analysis between these two plans.One-year after the surgery,the CFD analysis was conducted again on the post-operative aneurysm model to verify the selected surgical plan in terms of morphometric and hemodynamic properties changes in the aneurysm.Based on the CFD simulation and clinical experience,surgical Plan-A was adopted.One-year after the surgery,both the hemodynamic and morphological properties improved in the post-operative aneurysm model,indicating the recovery of the patient.The patient-specific aneurysm CFD analysis can help to determine a better surgical plan for patients with special cerebral aneurysms.This study showed how CFD analysis can be used to aid clinical diagnosis and treatment. | Shicheng He Juhui Qiu Wanling Liu Tieying Yin Dechuan Zhang Donghua Liao Haijun Zhang Yuxia Yin Guixue Wang | 2020 | Molecular & Cellular Biomechanics2020，17，2： | 0 |
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