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| 1 | Bacillus amyloliquefaciens Strain W19 can Promote Growth and Yield and Suppress Fusarium Wilt in Banana Under Greenhouse and Field Conditions显示文摘Plant growth-promoting rhizobacteria(PGPR) are considered to be the most promising agents for cash crop production via increasing crop yields and decreasing disease occurrence. The Bacillus amyloliquefaciens strain W19 can produce secondary metabolites(iturin and bacillomycin D) effectively against Fusarium oxysporum f. sp. cubense(FOC). In this study, the ability of a bio-organic fertilizer(BIO) containing strain W19 to promote plant growth and suppress the Fusarium wilt of banana was evaluated in both pot and field experiments. The results showed that application of BIO significantly promoted the growth and fruit yield of banana while suppressing the banana Fusarium wilt disease. To further determine the beneficial mechanisms of the strain, the colonization of green fluorescent protein-tagged strain W19 on banana roots was observed using confocal laser scanning microscopy and scanning electron microscopy. The effect of banana root exudates on the formation of biofilm of strain W19 indicated that the banana root exudates may enhance colonization. In addition, the strain W19 was able to produce indole-3-acetic acid(IAA), a plant growth-promoting hormone.The results of these experiments revealed that the application of strain W19-enriched BIO improved the banana root colonization of strain W19 and growth of banana and suppressed the Fusarium wilt. The PGPR strain W19 can be a useful biocontrol agent for the production of banana under field conditions. | WANG Beibei SHEN Zongzhuan ZHANG Fengge Waseem RAZA YUAN Jun HUANG Rong RUAN Yunze LI Rong SHEN Qirong | 2016 | Pedosphere2016，26，5： | 22 |
| 2 | Lower limits of evaluation parameters for the lower Paleozoic Longmaxi shale gas in southern Sichuan Province显示文摘Here we present six key parameters that have been applied to evaluate the Silurian Longmaxi shale gas accumulations of southern Sichuan Province.These parameters include richness of organic matter,single layer shale thickness,burial depth of the shale,maturity,shale properties,and brittle mineral content.In combination with drilling data,the lower limits of these six parameters for marine shale gas have been evaluated and the following conclusions are drawn:(1)Organic carbon recovery, gas content inversion,and production tests have been applied for the first time to measure the lower limit of TOC,which is determined to be 1.0%.(2)Based on the hydrocarbon generation and expulsion theory for source rocks and the characteristics of Longmaxi shale,the lower limit of the single-layer thickness is estimated to be 30 m,of which a thickness of at least 15 m should contain high-quality shale.(3)Based on the correlation of TOC and porosity,the lower limit of gas-filled porosity is 1.2%.(4)Other parameters,such as maturity,burial depth,and brittle mineral content have also been studied with regard to the geologic conditions of southern Sichuan.Based on the study results,an evaluation index system has been established for highly evolved marine shale gas,and the system has been applied successfully to geologically screened shale gas occurrences in southern Sichuan Province. | LI YanJun LIU Huan ZHANG LieHui LU ZongGang LI QiRong HUANG YongBin | 2013 | Science China Earth Sciences2013，56，5： | 20 |
| 3 | Rhizobacterium Bacillus amyloliquefaciens Strain SQRT3-Mediated Induced Systemic Resistance Controls Bacterial Wilt of Tomato显示文摘Tomato bacterial wilt caused by Ralstonia solanacearum seriously threats tomato growth in tropical and temperate regions around the world.This study reported an antagonistic bacterial strain, Bacillus amyloliquefaciens strain SQRT3, isolated from the rhizosphere soil of tomato plants, which strongly inhibited in vitro growth of pathogenic R.solanacearum.The suppression of tomato bacterial wilt by strain SQRT3 was demonstrated under greenhouse conditions.Additionally, induced systemic resistance(ISR) in tomato as one of the potential disease suppression mechanisms was investigated in the plants inoculated with the isolated bacterial strain SQRT3.The results showed that strain SQRT3 applied with R.solanacearum by drenching significantly reduced tomato bacterial wilt by 68.1% biocontrol efficiency(BE) and suppressed the R.solanacearum populations in the rhizosphere soil compared to the control only drenched with R.solanacearum.The BE of the isolated bacterial strain SQRT3 against tomato wilt increased to 84.1%by root-dipping.Tomato plants treated with both strain SQRT3 and R.solanacearum showed increases in activities of peroxidase and polyphenol oxidase compared with other treatments.The application of strain SQRT3 reduced membrane lipid peroxidation in tomato leaves.The expressions of marker genes for jasmonic acid-and salicylic acid-dependent signaling pathways were faster and stronger in tomato plants treated with both strain SQRT3 and R.solanacearum than in plants treated with either R.solanacearum or strain SQRT3 alone.Collectively, the findings indicated that strain SQRT3 can effectively control tomato wilt. | LI Chunyu HU Weicong PAN Bin LIU Yan YUAN Saifei DING Yuanyuan LI Rong ZHENG Xinyan SHEN Biao SHEN Qirong | 2017 | Pedosphere2017，27，6： | 18 |
| 4 | Strategies and Principles of Distributed Machine Learning on Big Data显示文摘 | Eric P. Xing Qirong Ho Dai Wei Pengtao Xie | 2016 | Engineering2016，2，2： | 15 |
| 5 | Changes of Hemoglobin and Hematocrit in Elderly Patients Receiving Lower Joint Arthroplasty without AIIogeneic Blood Transfusion显示文摘 | Qi Zhou Yiqin Zhou Haishan Wu Yuli Wu Qirong Qian Hui Zhao Yunli Zhu Peiliang Fu | 2015 | Chinese Medical Journal2015，，1： | 14 |
| 6 | The genesis of H_2S in the Weiyuan Gas Field, Sichuan Basin and its evidence显示文摘The Sinian Dengying Formation gas pool in Weiyuan is the oldest large-scale sulfur-bearing gas field in China, which has a H2S content ranging from 0.8% to 1.4%. The Cambrian Xixiangchi Formation gas pool discovered recently above the Dengying Formation contains gas geochemical behaviors similar to those of Dengying Formation but different in sulfur isotopes of H2S. Investigations show that though these two Sinian and Cambrian gas pools are separate ones, they share the same Cambrian source rock. The higher dry coefficient, heavier carbon isotopes, sulfur isotopes of sulfide, lower filling of gas pools, formation water characteristics, reservoir properties and H2S distribution, indicate that H2S in both the Sinian and Cambrian gas pools originates from TSR. The sulfur isotopes of sulfates have shown that H2S was formed in respective pools, namely hydrocarbons charged into the pools reacted with the Dengying Formation and the Xixiangchi Formation gypsum (TSR), respectively, to form H2S. Compared with sulfur isotopes of sulfates in each pool, δ34S values of H2S are 8‰ lighter for the Dengying Formation pool and 12‰ lighter for the Xixiangchi Formation pool, respectively, which is attributed to the difference in temperatures of TSR occurrence. The reservoir temperature of the Xixiangchi Formation pool is about 40℃ lower than that of the Dengying Formation pool. Temperature plays a controlling role in both the sulfur isotopic fractionation and amounts of H2S generation during TSR. | ZHU GuangYou ZHANG ShuiChang LIANG YingBo LI QiRong | 2007 | Chinese Science Bulletin2007，52，10： | 13 |
| 7 | Rhizosphere immunity: targeting the underground for sustainable plant health management显示文摘Managing plant health is a great challenge formodern food production and is further complicated by thelack of common ground between the many disciplinesinvolved in disease control. Here we present the concept ofrhizosphere immunity, in which plant health is consideredas an ecosystem level property emerging from networks ofinteractions between plants, microbiota and the surround-ing soil matrix. These interactions can potentially extendthe innate plant immune system to a point where therhizosphere immunity can fulfil all four core functions ofafull immune system: pathogen prevention, recognition,response and homeostasis. We suggest that consideringplant health from a meta-organism perspective will help indeveloping multidisciplinary pathogen management stra-tegies that focus on steering the whole plant-microbe-soilnetworks instead of individual components. This might beachieved by bringing together the latest discoveries inphytopathology, microbiome research, soil science andagronomy to pave the way toward more sustainable andproductive agriculture. | Zhong WEI Vill-Petri FRIMAN Thomas POMMIER Stefan GEISEN Alexandre JOUSSET Qirong SHEN | 2020 | Frontiers of Agricultural Science and Engineering2020，7，3： | 11 |
| 8 | Wogonoside inhibits tumor growth and metastasis in endometrial cancer via ER stress-Hippo signaling axis显示文摘Wogonoside,a bioactive flavonoid component derived from Scutellaria baicalensis Georgi,has been reported to inhibit tumor growth in mice bearing various types of cancer cells such as breast cancer,lung cancer,and leukemia cells.However,whether wogonoside could inhibit tumor growth of endometrial cancer has not been elucidated.In this study,we explored the function of wogonoside on tumor growth and the underlying mechanism on endometrial cancer.Firstly,we investigated the effect of wogonoside on endometrial cancer cells and found that wogonoside could significantly decrease cell proliferation and metastasis.Mechanistically,wogonoside could aggravate the extent of ER stress and upregulate the phosphorylation level of Mammalian Ste20-like kinase 1,leading to the activation of the Hippo signaling pathway.Taken together,in vitro and in vivo data demonstrated that wogonoside could be a potent inducer of ER stress and could be further developed into a promising therapy for endometrial cancer. | Shaorong Chen Zhuna Wu Yumin Ke Pingping Shu Caihong Chen Ruying Lin Qirong Shi | 2019 | Acta Biochimica et Biophysica Sinica2019，51，11： | 8 |
| 9 | Versatile on-chip light coupling and(de)multiplexing from arbitrary polarizations to controlled waveguide modes using an integrated dielectric metasurface显示文摘Metasurfaces have found broad applicability in free-space optics,while its potential to tailor guided waves remains barely explored.By synergizing the Jones matrix model with generalized Snell’s law under the phase-matching condition,we propose a universal design strategy for versatile on-chip mode-selective coupling with polarization sensitivity,multiple working wavelengths,and high efficiency concurrently.The coupling direction,operation frequency,and excited mode type can be designed at will for arbitrary incident polarizations,outperforming previous technology that only works for specific polarizations and lacks versatile mode controllability.Here,using silicon-nanoantenna-patterned silicon-nitride photonic waveguides,we numerically demonstrate a set of chip-scale optical couplers around 1.55μm,including mode-selective directional couplers with high coupling efficiency over 57%and directivity about 23 d B.Polarization and wavelength demultiplexer scenarios are also proposed with 67%maximum efficiency and an extinction ratio of 20 d B.Moreover,a chip-integrated twisted light generator,coupling free-space linear polarization into an optical vortex carrying 1 h orbital angular momentum(OAM),is also reported to validate the mode-control flexibility.This comprehensive method may motivate compact wavelength/polarization(de)multiplexers,multifunctional mode converters,on-chip OAM generators for photonic integrated circuits,and high-speed optical telecommunications. | YUAN MENG ZHOUTIAN LIU ZHENWEI XIE RIDE WANG TIANCHENG QI FUTAI HU HYUNSEOK KIM QIRONG XIAO XING FU QIANG WU SANG-HOON BAE MALI GONG XIAOCONG YUAN | 2020 | Photonics Research2020，8，4： | 8 |
| 10 | Geological Factors Controlling the Accumulation and High Yield of Marine-Facies Shale Gas: Case Study of the Wufeng-Longmaxi Formation in the Dingshan Area of Southeast Sichuan, China显示文摘The main geological factors controlling the accumulation and yield of marine-facies shale gas reservoirs are the focus of the current shale gas exploration and development research.In this study,the Wufeng-Longmaxi Formation in the Dingshan area of southeast Sichuan was investigated.Shale cores underwent laboratory testing,which included the evaluation of total organic carbon(TOC),vitrinite reflectance(Ro),whole-rock X-ray diffraction(XRD),pore permeability,and imaging through field emission scanning electron microscopy(FE-SEM).Based on the results of natural gamma ray spectrum logging,conventional logging,imaging logging,and seismic coherence properties,the exploration and development potential of shale gas in the Dingshan area have been discussed comprehensively.The results showed that(1)layer No.4(WF2-LM4)of the Wufeng-Longmaxi Formation has a Th/U ratio<2 and a Th/K ratio of 3.5–12.Graptolites and pyrite are relatively abundant in the shale core,indicating sub-high-energy and low-energy marine-facies anoxic reducing environments.(2)The organic matter is mainly I-type kerogen with a small amount of II1-type kerogen.There is a good correlation among TOC,Ro,gas content,and brittle minerals;the fracturing property(brittleness)is 57.3%.Organic and inorganic pores are moderately developed.A higher pressure coefficient is correlated with the increase in porosity and the decrease in permeability.(3)The DY1 well of the shale gas reservoir was affected by natural defects and important latestage double destructive effects,and it is poorly preserved.The DY2 well is located far from the Qiyueshan Fault.Large faults are absent,and upward fractures in the Longmaxi Formation are poorly developed.The well is affected by low tectonic deformation intensity,and it is well preserved.(4)The Dingshan area is located at the junction of the two sedimentary centers of Jiaoshiba and Changning.The thickness of the high-quality shale interval(WF2-LM4)is relatively small,which may be an important reason for the unstable production of shale gas thus far.Based on the systematic analysis of the geological factors controlling high-yield shale gas enrichment in the Dingshan area,and the comparative analysis with the surrounding typical exploration areas,the geological understanding of marine shale gas enrichment in southern China has been improved.Therefore,this study can provide a useful reference for shale gas exploration and further development. | FAN Cunhui ZHONG Cheng ZHANG Yu QIN Qirong HE Shun | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 7 |
| 11 | Decreased nitrous oxide emissions associated with functional microbial genes under bio-organic fertilizer application in vegetable fields显示文摘Bio-organic fertilizers enriched with plant growth-promoting microbes(PGPMs)have been widely used in crop fields to promote plant growth and maintain soil microbiome functions.However,their potential effects on N_(2)O emissions are of increasing concern.In this study,an in situ measurement experiment was conducted to investigate the effect of organic fertilizer containing Trichoderma guizhouense(a plant growth-promoting fungus)on soil N_(2)O emissions from a greenhouse vegetable field.The following four treatments were used:no fertilizer(control),chemical fertilizer(NPK),organic fertilizer derived from cattle manure(O),and organic fertilizer containing T.guizhouense(O+T,referring to bio-organic fertilizer).The abundances of soil N cycling-related functional genes(amoA)from ammonium-oxidizing bacteria(AOB)and archaea(AOA),as well as nirS,nirK,and nosZ,were simultaneously determined using quantitative PCR(qPCR).Compared to the NPK plot,seasonal total N_(2)O emissions decreased by 11.7%and 18.7%in the O and O+T plots,respectively,which was attributed to lower NH_(4)^(+)-N content and AOB amoA abundance in the O and O+T plots.The nosZ abundance was significantly greater in the O+T plot,whilst the AOB amoA abundance was significantly lower in the O+T plot than in the O plot.Relative to the organic fertilizer,bio-organic fertilizer application tended to decrease N_(2)O emissions by 7.9%and enhanced vegetable yield,resulting in a significant decrease in yield-scaled N_(2)O emissions.Overall,the results of this study suggested that,compared to organic and chemical fertilizers,bio-organic fertilizers containing PGPMs could benefit crop yield and mitigate N_(2)O emissions in vegetable fields. | Yajun GENG Yiming YUAN Yingcheng MIAO Junzhang ZHI Mengyuan HUANG Yihe ZHANG Hong WANG Qirong SHEN Jianwen ZOU Shuqing LI | 2021 | Pedosphere2021，31，2： | 7 |
| 12 | Surgical Management of Retinal Detachment Resulting from Macular Hole in a Setting of High Myopia显示文摘Purpose:To evaluate the anatomical and visual outcomes of pars plana vitrectomy (PPV) with internal limiting membrane (ILM).peeling and use of retinal tamponade for retinal detachments resulting from macular hole (MHRD) in highly myopic eyes. Methods:.Twenty-nine highly myopic patients.(29 eyes) underwent PPV with ILM peeling and retinal tamponade for MHRD were enrolled. Demographics and best-corrected visual acuity.(BCVA).were measured preoperatively and at final follow-up. Anatomical success and macular hole closure were analyzed. Results:.Patients' mean age of patients was 58.7±10.6 years, mean follow-up was 11.7±7.4 months. Twenty three eyes (23/26,88.5%)undergoing primary PPV combined with ILM peeling had successful initial retinal reattachment, including 19 eyes (19/19, 100%) with silicone oil tamponade and in 4 eyes (4/7,57.1%).with sulfur hexafluoride.(C3F8).tamponade. Overall anatomical success was achieved in 27 eyes (27/29, 93.1%)..The macular hole closure was observed in 17 eyes (17/26, 65.4%) with final anatomical success. Compared to preoperative BCVA,.the mean postoperative BCVA in the eyes with anatomical success was significantly improved (P = 0.007, Wilcoxon signed rank test). Conclusion:.As a primary or secondary procedure,.PPV combined with ILM peeling and usage of retinal tamponade serves as an effective method for MHRD in highly myopic eyes. | Liguo Feng Xiaohong Jin Jiuke Li Jing Zhai Wei Fang Jianfeng Mo Qirong Feng Yumin Li | 2012 | Eye Science2012，27，2： | 7 |
| 13 | Development Phases and Mechanisms of Tectonic Fractures in the Longmaxi Formation Shale of the Dingshan Area in Southeast Sichuan Basin, China显示文摘Shale gas has currently attracted much attention during oil and gas exploration and development. Fractures in shale have an important influence on the enrichment and preservation of shale gas. This work studied the developmental period and formation mechanism of tectonic fractures in the Longmaxi Formation shale in the Dingshan area of southeastern Sichuan Basin based on extensive observations of outcrops and cores, rock acoustic emission(Kaiser) experiments, homogenization temperature of fracture fill inclusions, apatite fission track, thermal burial history. The research shows that the fracture types of the Longmaxi Formation include tectonic fractures, diagenetic fractures and horizontal slip fractures. The main types are tectonic high-angle shear and horizontal slip fractures, with small openings, large spacing, low densities, and high degrees of filling. Six dominant directions of the fractures after correction by plane included NWW, nearly SN, NNW, NEE, nearly EW and NW. The analysis of field fracture stage and fracture system of the borehole suggests that the fractures in the Longmaxi Formation could be paired with two sets of plane X-shaped conjugate shear fractures, i.e., profile X-shaped conjugate shear fractures and extension fractures. The combination of qualitative geological analysis and quantitative experimental testing techniques indicates that the tectonic fractures in the Longmaxi Formation have undergone three periods of tectonic movement, namely mid-late Yanshanian movement(82–71.1 Ma), late Yanshanian and middle Himalaya movements(71.1–22.3 Ma), and the late Himalayan movement(22.3–0 Ma). The middle-late period of the Yanshanian movement and end of the Yanshanian movement-middle period of the Himalayan movement were the main fractureforming periods. The fractures were mostly filled with minerals, such as calcite and siliceous. The homogenization temperature of fracture fill inclusions was high, and the paleo-stress value was large; the tectonic movement from the late to present period was mainly a slight transformation and superposition of existing fractures and tectonic systems. Based on the principle of tectonic analysis and theory of geomechanics, we clarified the mechanism of the fractures in the Longmaxi Formation, and established the genetic model of the Longmaxi Formation. The research on the qualitative and quantitative techniques of the fracture-phase study could be effectively used to analyze the causes of the marine shale gas fractures in the Sichuan Basin. The research findings and results provide important references and technical support for further exploration and development of marine shale gas in South China. | FAN Cunhui HE Shun ZHANG Yu QIN Qirong ZHONG Cheng | 2018 | Acta Geologica Sinica(English Edition)2018，92，6： | 7 |
| 14 | Metamorphic peridotite and rock series of ophiolite belt in Mt. Ailao, Yunnan Province显示文摘The metamophic peridotite of ophiolite belt in Mt. Ailao is composed of lherzolite and harzburgite. The former shows the charateristics of primary pyrolite and the latter shows those of deleted (relict)pyrolite. By partial melting of lherzolite, two primary magmas: tholeiitic magma and picrite-basalt magma are formed. The former evoluted into gabbro-diabase-pyroxenic basalt rock series and show the characteristics of MORB; while the latter evoluted into gabbro-diorite-albite basalt-picrite basalt one, and show the characteristics of para-MORB. | Shen Shangyue Wei Qirong Cheng Huilan Mo Xuanxue | 1998 | Chinese Science Bulletin1998，43，11： | 6 |
| 15 | Optical meta-waveguides for integrated photonics and beyond显示文摘The growing maturity of nanofabrication has ushered massive sophisticated optical structures available on a photonic chip.The integration of subwavelength-structured metasurfaces and metamaterials on the canonical building block of optical waveguides is gradually reshaping the landscape of photonic integrated circuits,giving rise to numerous metawaveguides with unprecedented strength in controlling guided electromagnetic waves.Here,we review recent advances in meta-structured waveguides that synergize various functional subwavelength photonic architectures with diverse waveguide platforms,such as dielectric or plasmonic waveguides and optical fibers.Foundational results and representative applications are comprehensively summarized.Brief physical models with explicit design tutorials,either physical intuition-based design methods or computer algorithms-based inverse designs,are cataloged as well.We highlight how meta-optics can infuse new degrees of freedom to waveguide-based devices and systems,by enhancing light-matter interaction strength to drastically boost device performance,or offering a versatile designer media for manipulating light in nanoscale to enable novel functionalities.We further discuss current challenges and outline emerging opportunities of this vibrant field for various applications in photonic integrated circuits,biomedical sensing,artificial intelligence and beyond. | Yuan Meng Yizhen Chen Longhui Lu Yimin Ding Andrea Cusano Jonathan A.Fan Qiaomu Hu Kaiyuan Wang Zhenwei Xie Zhoutian Liu Yuanmu Yang Qiang Liu Mali Gong Qirong Xiao Shulin Sun Minming Zhang Xiaocong Yuan Xingjie Ni | 2021 | Light(Science & Applications)2021，10，12： | 6 |
| 16 | Effects of Local Nitrogen Supply on Water Uptake of Bean Plants in a Split Root System显示文摘到本地氮的效果在水和滋养的吸收上供应的学习,法语的豆子(Phaseolus 粗俗) 植物在一个裂口根系被种。与不同的氮形式供应的 Fivetreatments 被比较:同类的硝酸盐(NN ) 和同类的铵(AA ) 供应,硝酸盐和铵(NA ) 的空间地分开的供应,与 N 免费的营养液供应的根系的一半,有任何一个硝酸盐(N0 ) 的另外的一半或铵(A0 ) 。结果显示出那在处理的发作以后的 10 天,在与 NA 对待的供应硝酸盐的容器的根干物质(DM ) 在供应 theammonium 的容器比那高多于 two times。从与 NA 对待的供应硝酸盐的容器的水举起比在铵供应下面是 281%higher。在处理 N0 和 A0, N 的本地供应导致了清楚地更高的根 DM,并且从供应硝酸盐的容器的水举起比在 -N 容器高是 82% 。在 A0 植物,然而,从 -N 营养液的水举起比从供应铵的容器高是 129% 。这显示补偿效果,它导致了处理 AA 和 A0 的全部的水举起的几乎相同的率,它有可比较的射击 DMand 叶面积。铵供应减少了钾和镁吸收。水举起断然与 N, Mg 和 K 举起被相关…… | Shiwei Guo Qirong Shen Holger Brueckt | 2007 | Journal of Integrative Plant Biology2007，49，4： | 6 |
| 17 | Production of Free Amino Acid and Short Peptide Fertilizer from Rapeseed Meal Fermentation Using Bacillus flexus NJNPD41 for Promoting Plant Growth显示文摘Free amino acids and short peptides(FAPS)that play an important role in plant nutrition can be extracted from rapeseed meal(RSM)by microbial enzymolysis.The enzymolytic activity of one bacterial strain isolated from RSM for the production of FAPS fertilizer(FAPSF)via solid-state fermentation,as well as its detoxification activity for isothiocyanates and oxazolidinethione,was investigated in this study.The strain NJNPD41 isolated from RSM piled-soil possessed effective proteolytic activity and was identified as Bacillus flexus on the basis of its morphological,physiological,and biochemical properties,as well as 16S rDNA analysis.Compared to the uninoculated control,inoculation with the strain NJNPD41 significantly increased the yield of total free amino acids and short peptides by 115%and decreased the content of isothiocyanates and oxazolidinethione by 53%and 60%,respectively,after solid-state fermentation.The pot and field experiments showed that FAPSF significantly promoted eggplant growth and enhanced the fruit yield and quality of eggplant compared to the control.In conclusion,this study provided a novel method for the high-value utilization of RSM to produce high-quality and low-toxicity FAPSF using the newly isolated strain B.flexus NJNPD41. | LIU Hongjun ZHONG Xi HUANG Yan QIAO Cece SHAO Cheng LI Rong SHEN Qirong | 2018 | Pedosphere2018，28，2： | 5 |
| 18 | Discovery of the Proterozoic low-grade metamorphicsubmarine carbonatite lavas in China显示文摘The carbonatite lavas found in the Kunyang Group were formed in submarine extrusive environment. Many igneous features (e.g. colors, textures, structures, minerals, inclusions) are clear. But most of their petrologic characteristics are different from typical carbonatites over the world. Most petrologic details of the rocks are given by comparison with other carbonatites and adjacent sedimentary dolomites. The discovery of the lavas proves that the carbonatite volcano also existed in Kunyang rift. | Yongbei Zhang Qirong Wei Chengyan Xiu Hao Wang | 1998 | Chinese Science Bulletin1998，43，5： | 4 |
| 19 | Comparison of Clinical and Epidemiological Characteristics of Asymptomatic and Symptomatic SARS-CoV-2 Infection in Children显示文摘To understand the epidemiological and clinical features of the symptomatic and asymptomatic pediatric cases of COVID-19,we carried out a prospective study in Shanghai during the period of January 19 to April 30,2020.A total of 49 children(mean age 11.5±5.12 years)confirmed with SARS-CoV-2 infection were enrolled in the study,including 11(22.4%)domestic cases and 38(77.6%)imported cases.Nine(81.8%)local cases and 12(31.6%)imported cases had a definitive epidemiological exposure.Twenty-eight(57.1%)were symptomatic and 21(42.9%)were asymptomatic.Neither asymptomatic nor symptomatic cases progressed to severe diseases.The mean duration of viral shedding for SARS-CoV-2 in upper respiratory tract was 14.1±6.4 days in asymptomatic cases and 14.8±8.4 days in symptomatic cases(P>0.05).Forty-five(91.8%)cases had viral RNA detected in stool.The mean duration of viral shedding in stool was 28.1±13.3 days in asymptomatic cases and 30.8±18.6 days in symptomatic participants(P>0.05).Children<7 years shed viral RNA in stool for a longer duration than school-aged children(P<0.05).Forty-three(87.8%)cases had seropositivity for antibodies against SARS-CoV-2 within 1–3 weeks after confirmation with infection.In conclusion,asymptomatic SARS-CoV-2 infection may be common in children in the community during the COVID-19 pandemic wave.Asymptomatic cases shed viral RNA in a similar pattern as symptomatic cases do.It is of particular concern that asymptomatic individuals are potentially seed transmission of SARS-CoV-2 and pose a challenge to disease control. | Jiehao Cai Xiangshi Wang Jun Zhao Yanling Ge Jin Xu He Tian Hailing Chang Aimei Xia Jiali Wang Jinqiang Zhang Zhongqiu Wei Jingjing Li Chuning Wang Jianshe Wang Qirong Zhu Xiaowen Zhai Mei Zeng | 2020 | Virologica Sinica2020，35，6： | 4 |
| 20 | Erythromycin loaded by tetrahedral framework nucleic acids are more antimicrobial sensitive against Escherichia coli(E.coli)显示文摘Erythromycin is a commonly used broad-spectrum antibiotic,but resistance to this antibiotic makes its use less effective.Considerable efforts,beside finding alternatives,are needed to enhance its antimicrobial effect and stability against bacteria.Tetrahedral framework nucleic acids(tFNAs),a novel delivery vehicle with a three-dimensional nanostructure,have been studied as a carrying platform of antineoplastic drugs.In this study,the use of tFNAs in delivering erythromycin into Escherichia coli(E.coli)was investigated for the first time.The tFNAs vehicle increased the bacterial uptake of erythromycin and promoted membrane destabilization.Moreover,it increased the permeability of the bacterial cell wall,and reduced drug resistance by improving the movement of the drug across the membrane.The tFNAs-based delivery system enhanced the effects of erythromycin against E.coli.It may therefore provide an effective delivery vehicle for erythromycin in targeting antibiotic-resistant bacteria with thick cell wall. | Yue Sun Yuhao Liu Bowen Zhang Shirong Shi Tao Zhang Dan Zhao Taoran Tian Qirong Li Yunfeng Lin | 2021 | Bioactive Materials2021，6，8： | 4 |
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