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| 1 | Theoretical Analysis and Experimental Verification on Flow Field of Piezoelectric Pump with Unsymmetrical Slopes Element显示文摘Regular valveless piezoelectric pumps have rectifying elements outside their chambers to produce net flow.These rectifying elements outside the chamber will increase the overall volume of the pump and prevent its minimization.Valveless piezoelectric pump with unsymmetrical slopes elements(USE),proposed in this paper,differs from other valveless pumps in that it is easy to be minimized by developing the chamber bottom as such a rectifying element.In this research,the working principle of the proposed pump was analyzed first.Numerical models were thereby established and numerical simulation was conducted to the chamber flow field with the method of time-dependent velocity.The effects of the USEs on the flow field in the chamber were shown clearly in simulation.And the particular feature of flow field in the chamber was discovered.It behaves a complex flow field,in which strong turbulent occurs companying a lot of vortexes in different directions and different sizes.This feature is just opposite to what regular piezoelectric pumps expect:a moderate flow field.The turbulent flow could be used to have different liquids stirred and well mixed in the chamber to produce homogeneous solution,emulsion or turbid liquid.Meanwhile,numerical simulation also presents the effect of the angles difference of the two slopes upon the flow field,and upon the flow rate of the pump,which fits to the theoretical analysis.Experiments with the proposed pump were also conducted to verify the numerical results.In these experiments,six USEs with different slope angles were used for efficiency tests,which proved the validity and reliability of the numerical analysis.The data obtained from numerical analysis agree well with that from the experiments.The errors ranged from 4.4% to 14.8% with their weighted average error being 9.7%. | XIA Qixiao ZHANG Jianhui LEI Hong CHENG Wei | 2009 | Chinese Journal of Mechanical Engineering2009，22，5： | 18 |
| 2 | Analysis on Flow Field of the Valveless Piezoelectric Pump with Two Inlets and One Outlet and a Rotating Unsymmetrical Slopes Element显示文摘Typically,liquid pump and liquids mixer are two separate devices.The invention of piezoelectric pump makes it possible to integrate the two devices.Hower,the existing piezoelectric mixing-pumps are larger because the need the space outside the chamber,and another shortcome of them is that they cannot adjust the mixing ratio of two liquids.In this paper,a new piezoelectric pump being capable of integrating mixer and pump is presented,based on the theory of the piezoelectric pump with the unsymmetrical slopes element(USE).Besides the features of two inlets and one outlet,the piezoelectric pump has a rotatable unsymmetrical slopes element(RUSE).When the pump works,two fluids flow into the inlet channels respectively.Then the RUSE controls the ratio of the two flows by adjusting the flow resistances of the two inlet channels.The fluids form a net flow due to the USE principle,while they are mixed into a homogeneous solution due to strong turbulence flow field and complex vortices generated by RUSE in the chamber.And then the solution flows through the outlet.Firstly,the theoretical analysis on this pump is performed.Meanwhile,the flow field in the chamber is calculated and simulated.And then,the relationship between the flows of the two channels and the rotating angle of the RUSE is set up and analyzed.Finally,experiment with the proposed pump is carried out to verify the numerical results.A RUSE with 20° slope angle is used in the experiment.Four sets of data are tested with the RUSE at the rotating angles of 0°,6°,11°,and 16°,respectively,corresponding to the numerical models.The experimental results show that the empirical data and the theoretical data share the same trend.The maximum error between the theoretical flow and the experimental flow is 11.14%,and the maximum error between the theoretical flow ratio of the two inlets and the experimental one is 2.5%.The experiment verified the theoretical analysis.The proposed research provides a new idea for integration of micro liquids mixer and micro liquids pump. | XIA Qixiao ZHANG Jianhui LEI Hong CHENG Wei | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 13 |
| 3 | Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice显示文摘Oral exposure to toxic metals such as cadmium(Cd), lead(Pb), copper(Cu) and aluminum(Al) can induce various adverse health effects in humans and animals. However, the effects of these metals on the gut microbiota have received limited attention. The present study demonstrated that long-term toxic metal exposure altered the intestinal microbiota of mice in a metal-specific and time-dependent manner.Subchronic oral Cu exposure for eight weeks caused a profound decline in gut microbial diversity in mice,whereas no significant changes were observed in groups treated with other metals. Cd exposure significantly increased the relative abundances of organisms from the genera Alistipes and Odoribacter and caused marked decreases in Mollicutes and unclassified Ruminococcaceae. Pb exposure significantly decreased the abundances of eight genera: unclassified and uncultured Ruminococcaceae, unclassified Lachnospiraceae, Ruminiclostridium_9, Rikenellaceae_RC9_gut_group, Oscillibacter, Anaerotruncus and Lachnoclostridium. Cu exposure affected abundances of the genera Alistipes, Bacteroides,Ruminococcaceae_UCG-014, Allobaculum, Mollicutes_RF9_norank, Rikenellaceae_RC9_gut_group,Ruminococcaceae_unclassified and Turicibacter. Al exposure increased the abundance of Odoribacter and decreased that of Anaerotruncus. Exposure to any metal for eight weeks significantly decreased the abundance of Akkermansia. These results provide a new understanding regarding the role of toxic metals in the pathogenesis of intestinal and systemic disorders in the host within the gut microbiota framework. | Qixiao Zhai Tianqi Li Leilei Yu Yue Xiao Saisai Feng Jiangping Wu Jianxin Zhao Hao Zhang Wei Chen | 2017 | Science Bulletin2017，62，12： | 12 |
| 4 | Principle and Experimental Verification of Caudal-fin-type Piezoelectric-stack Pump with Variable-cross-section Oscillating Vibrator显示文摘In the traditional flow-resistance-differential (FRD) type valve-less piezoelectric pump,the generated outflow and pressure are discontinuous because of the inherent periodicity and fluctuation of the pump.To overcome these drawbacks,utilizing the bending vibration of piezoelectric bimorph to drive fluid was conducted.However,our investigation on the current status of this piezoelectric bimorph pump shows that larger driving force and vibration amplitude are required for fluid pumping;the pumping can be realized through the centrifugal force;and the mechanism of fluid pumping is no longer further studied.Based on these cases,the paper designed a piezoelectric-stack pump with variable-cross-section oscillating (VCSO) vibrator by imitating the swing of the caudal-fin of tuna,and the pump is neither the rotating type nor the volumetric type according to the taxonomy.The interaction between the oscillating vibrator and the fluid parcel is firstly analyzed from the viewpoint of momentum conservation,and the analytical expression of pump flow rate is obtained.Then the modal and harmonic response analyses on the vibrator immerged in water are carried out.From the analyses the first two orders resonance frequencies are 832 Hz and 1 939 Hz,respectively,and the peak value of the tip amplitude is 0.6 mm.Laser Doppler vibrometer is used to measure both the frequency and vibration amplitude,and the determined first two orders resonance frequencies are 617 Hz and 1 356 Hz,respectively.The measured tip amplitude reaches to the peak value of 0.3 mm.At last,experimental measurement for the flow rates with different driving frequencies is conducted.The results show that the flow rate can reach 560 mL/min at 1 370 Hz when the pump runs under the backpressure of 30 mm water column.And the flow rate is as much as 560% of that of experiment results carried out by researchers from Brazil.The proposed pump innovates in both theory and taxonomy;in addition,the pump overcomes the drawbacks such as large flow fluctuation and low flow rate in the traditional FRD type pumps,which will help to broaden the application of the valve-less piezoelectric pump. | HU Xiaoqi ZHANG Jianhui HUANG Yi XIA Qixiao HUANG Weiqing ZHAO Chunsheng | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 11 |
| 5 | Effects of key factors of rotary triboelectrostatic separator on efficiency of fly ash decarbonization显示文摘On the basis of understanding the principle of rotary triboelectrostatic separation, dynamic analysis of charged fly ash particles aimed at determining the key factors and separation experiments to improve decarbonization efficiency had been carried out Variables of electrode plate voltage and corrected wind speed are the key factors which affect the decarbonization efficiency on the separation of fly ash, The results of separation experiments show that:(1) With the plate voltage increasing, the efficiency of decarbonization continuously rises and in its selected range, the optimal voltage level is 45 KV;(2) The corrected wind speed can impact the efficiency of decarbonization significantly: with the speed increasing, the efficiency of decarbonization shows a trend of first decline, then increase and decrease again, and in its selected range, the optimal speed is 2.0 m/s. This study is of significance for the improvement of rotary triboelectrostatic separation performance and its decarbonization separation efficiency. | Tao Youjun Zhang Ling Tao Dongping Xian Yushuai Sun Qixiao | 2017 | International Journal of Mining Science and Technology2017，27，6： | 10 |
| 6 | Theoretical Analysis and Experimental Verification on Valve-less Piezoelectric Pump with Hemisphere-segment Bluff-body显示文摘Existing researches on no-moving part valves in valve-less piezoelectric pumps mainly concentrate on pipeline valves and chamber bottom valves,which leads to the complex structure and manufacturing process of pump channel and chamber bottom.Furthermore,position fixed valves with respect to the inlet and outlet also makes the adjustability and controllability of flow rate worse.In order to overcome these shortcomings,this paper puts forward a novel implantable structure of valve-less piezoelectric pump with hemisphere-segments in the pump chamber.Based on the theory of flow around bluff-body,the flow resistance on the spherical and round surface of hemisphere-segment is different when fluid flows through,and the macroscopic flow resistance differences thus formed are also different.A novel valve-less piezoelectric pump with hemisphere-segment bluff-body(HSBB)is presented and designed.HSBB is the no-moving part valve.By the method of volume and momentum comparison,the stress on the bluff-body in the pump chamber is analyzed.The essential reason of unidirectional fluid pumping is expounded,and the flow rate formula is obtained.To verify the theory,a prototype is produced.By using the prototype,experimental research on the relationship between flow rate,pressure difference,voltage,and frequency has been carried out,which proves the correctness of the above theory.This prototype has six hemisphere-segments in the chamber filled with water,and the effective diameter of the piezoelectric bimorph is 30mm.The experiment result shows that the flow rate can reach 0.50 mL/s at the frequency of 6 Hz and the voltage of 110 V.Besides,the pressure difference can reach 26.2 mm H2O at the frequency of 6 Hz and the voltage of 160 V.This research proposes a valve-less piezoelectric pump with hemisphere-segment bluff-body,and its validity and feasibility is verified through theoretical analysis and experiment. | JI Jing ZHANG Jianhui XIA Qixiao WANG Shouyin HUANG Jun ZHAO Chunsheng | 2014 | Chinese Journal of Mechanical Engineering2014，27，3： | 8 |
| 7 | Theory and experimental verification of valveless piezoelectric pump with rotatable unsymmetrical slopes显示文摘A valveless piezoelectric pump with rotatable unsymmetrical slopes is developed in this research.It has the following features:The pump integrates driving and transporting,and it can mix different fluids while transporting them.In this paper,firstly,the design of the valveless piezoelectric pump with rotatable unsymmetrical slopes was proposed,and the single-direction flow principle was explained.Then,the fluid mechanics model of the valveless piezoelectric pump with rotatable unsymmetrical slopes was established.Meanwhile,the numerical simulation of the pump was performed.Finally,the experiments on relationship between the rotation angles of the slope and the flow rates were conducted.The experimental results showed that the maximum flow was 32.32 mL min 1.The maximum relative error between the theoretical results and the experimental ones was 14.59%.For the relationship between rotation angles and flow ratio of two inlets,the relative error between the experimental and theoretical maxima was 3.75%.Thus,the experiments proved the feasibility of the pump design and verified the theory. | ZHANG JianHui XIA QiXiao HUANG Yi LENG XueFei HUANG Jun ZHAO ChunSheng | 2011 | Science China(Technological Sciences)2011，54，11： | 7 |
| 8 | Targeting Gut Microbiota Dysbiosis: Potential Intervention Strategies for Neurological Disorders显示文摘It is well known that the gut microbiota plays an extremely important role in modulating host physiological functions such as immunity and metabolic homeostasis.In recent years,accumulated evidence has revealed that the gut microbiota can regulate the functions of the central nervous system(CNS)through the gut-brain axis,which provides a novel insight into the interactions between the gut and brain.This review focuses on the molecular mechanism of the crosstalk between the gut microbiota and the brain via the gut-brain axis,and on the onset and development of neurological disorders triggered by gut microbiota dysbiosis.These topics are followed by a critical analysis of potential intervention strategies targeting gut microbiota dysbiosis,including the use of probiotics,prebiotics,synbiotics,and diets.While research on the microbiota-gut-brain axis is still in its relative infancy,clarifying the molecular mechanism that underlies how the gut microbiota regulates neurological functions not only holds the promise of revealing potentially novel pathogeneses of neurological disorders,but also may lead to the development of potential diagnosis biomarkers and intervention strategies targeting microbiota dysbiosis for neurological disorders. | Wanqiang Wu Qingmin Kong Peijun Tian Qixiao Zhai Gang Wang Xiaoming Liu Jianxin Zhao Hao Zhang Yuan Kun Lee Wei Chen a | 2020 | Engineering2020，6，4： | 7 |
| 9 | Characterization of Humic Fractions in a ^(15)N-labelled Soil by Solid-State ^(13)C and ^(15)N NMR显示文摘Five humic fractions were obtained from a uniformly 15N-labelled soil by extraction with 0.1 mol L-1 Na4P207, 0.1 mol L-1 NaOH, and HF/HCI-0.1 mol L-1 NaOH, consecutively, and analyzed by 13C and 15N CPMAS NMR (cross polarization and magic angle spinning nuclear magnetic resonance). Compared with those of native soils humic fractions studied as a whole contained more alkyls, methoxyls and O-alkyls, being 27%-36%, 17%-21% and 36%-40%, respectively, but fewer aromatics and carboxyls (being 14%-20% and 13%-90%, respectively). Among those humic fractions, the humic acid (HA) and fulvic acid (FA) extracted by 0.1 mol L-1 Na4P207 contained slightly more carboxyls than corresponding humic fractions extracted by 0.1 mol L-1 NaOH, and the HA extracted by 0.1 mol L-1 NaOH after treatment with HF/HCI contained the least aromatics and carboxyls. The distribution of nitrogen functional groups of soil humic fractions studied was quite similar to each other and also quite similar to that of humic fraction from native soils. More than 75% of total N in each fraction was in amide form, with 9%-13% present as aromatic and/or aliphatic amines and the remainder as hoterocyclic N. | CHENG LILI, WEN QIXIAO and CHEN BIYUN Institute of Soil Science, the Chinese Academy of Sciences, Nanjing 210008 (China) | 2001 | Pedosphere2001，11，2： | 4 |
| 10 | ^(15)N NMR Spectroscopic Study on Nitrogen Forms in Humic Substances of Soils显示文摘Nitrogen forms of humic substances from a subalpine meadow soil, a latentic red soil and a weathered coal and the effect of acid hydrolysis on N structures of soil humic substances were studied by using 15N cross-polarization magic angle spinning nuclear magnetic resonance (CPMAS NMR) spectroscopy. Of the detectable 15N-signal intensity in the spectra of soil humic substances 71%-79% may be attributed to amide groups, 10%-18% to aromatic/aliphatic amines and 6%~11% to indole- and pyrrole-like N. Whereas in the spectrum of the fulvic acid from weathered coal 46%, at least, of the total 15N-signal intensity might be assigned to pyrrole-like N, 14% to aromatic/aliphatic ammes, and the remaining intensities could not be assigned with certainty. Data on nonhydrolyzable residue of protein-sugar mixture and a 15N-labelled soil fulvic acid confirm the formation of nonhydrolyzable heterocyclic N during acid hydrolysis. Project (No. 39790100) supported by the National Natural Science Foundation of China. | WEN QIXIAO, ZHUO SUNENG and CHENG LILI (Institute of Soil Science, the Chinese Academy of Sciences, P.O. Box 821, Nanjing 210008 (China)) | 2001 | Pedosphere2001，11，1： | 2 |
| 11 | Lactobacillus plantarum CCFM8610 Alleviates Irritable Bowel Syndrome and Prevents Gut Microbiota Dysbiosis:A Randomized,Double-Blind,Placebo-Controlled,Pilot Clinical Trial显示文摘Irritable bowel syndrome with diarrhea(IBS-D)is chronic intestinal dysfunction with diarrhea and othercomplicated clinical symptoms,and it has a great impact on the daily life and mental state of patients.Some studies have reported that ingestion of probiotics can significantly alleviate a variety of intestinaldiseases.The pupose of this study was to investigate the IBS-D-alleviating effects of a probiotic strain,lactobacillus plantarum(L.plantarum)CCFM8610,with multiple health-promoting effects.The studywas a 12-week,randomized,double-blind,placebo-controlled,pilot clinical trial.Seventy-five patientswere randomly assigned to receive the placebo,oligosaccharides,or L.plantarum CCFM8610(1×10^(10) colony-forming units(CFU)per day),with a 2-week run-in period,an 8-week intervention period,anda 2-week follow-up observation period.The patients'clinical symptoms and quality of life were exam-ined by the IBS symptom severity scale(IBS-SsS)and the IlBS quality of life scale(IBS-QOL).Changes ingut microbiota composition and diversity were measured at the end of the intervention period.The oraladministration of L.plantarum CCFM8610 significantly decreased the IBS-SSS and IBS-QOL scores,reduced IBS-D symptom severity,recovered gut microbiota diversity,decreased the relative abundanceof bloating-related genus Methanobrevibacter,and increased the relative abundance of butyric acid-producing genera,including Anaerostipes,Anaerotruncus,Bifidobacterium,Butyricimonas,andOdoribacter.These findings suggest that ingestion of L.plantarum CCFM8610 can significantly alleviate clinical symptoms and gut microbiota dysbiosis in IBS-D patients.The IBS-D-alleviating effect of L.plan-tarum CCFM8610 may be related to theincrease in the relative abundance of butyric acid-producing genera in the intestine. | Yang Liu Xinjie Yu Leilei Yu Fengwei Tian Jianxin Zhao Hao Zhang Long Qian Qun Wang Zhengqing Xue Qixiao Zhai Wei Chen | 2021 | Engineering2021，7，3： | 2 |
| 12 | ProgressinPharmacdogical Research of Herba Siegesbeckiae 显示文摘 | WANG Fahui FENG Qixiao HUANG Chaowen(王发辉 冯起校 黄超文) | 2011 | Journal of Liaoning University of Traditional Chinese Medicine2011，13，10： | 1 |
| 13 | Capsular polysaccarides of probiotics and their immunomodulatory roles显示文摘Studies have determined the immunomodulatory activities of cell-surface polysaccharides of lactic acid bacteria(LAB)and Bacteroides;however,the mechanisms,synthesis,regulation,structure,and functional links have not been systematically discussed.We first introduce the structure of the capsular poly saccharides(CPS s)of commonly studied probiotics and Bacteroides.Wzx-Wzy dependent and ATP-binding cassette(ABC)transporter-dependent pathways are the two main biosynthesis and secretion of CPS pathways.The genes known to be associated with these two pathways are mainly those associated with priming glycosyltransferase(pGT);a variable number of genes encoding for different glycosyl transferases(GTs);Wzx/Wzy-encoding enzymes related to flippases and polymerases;and ABC-transporter genes.In addition,the effects of CPSs on host immunity as well as their related underlying mechanisms are described.Surface polysaccharides on probiotics can serve as a mask to aid in their escape from attacks from the host’s immune system.In turn,they also exhibit immunomodulatory activities,such as strengthening the functions of macrophages,promoting the maturation of antigen-presenting cells,and inducing regulatory T cells.All of these effects of cell-surface polysaccharides exhibit their significant protective properties in immunocompromised diseases,such as colitis,arthritis,and dermatitis.Finally,we focused on their structure and functional links. | Jing Li Saisai Feng Leilei Yu Jianxin Zhao Fengwei Tian Wei Chen Qixiao Zhai | 2022 | Food Science and Human Wellness2022，11，5： | 1 |
| 14 | Simulation of tree and its swaying with wind generated by L-system显示文摘This paper constructs a tree model by using the 3D stochastic and L system with brackets. Adjusting the range of the parameters, the present method ensures a favorable randomness and reflects the reality and the real time. Based on a simple mechanical model, the simulation of the phenomenon of wind swaying trees satisfies visual effects well. | Liu Ziping Xia Qixiao Yu Yue | 2017 | Computer Aided Drafting,Design and Manufacturing2017，27，1： | 1 |
| 15 | Lactobacillus plantarum CCFM8661 Alleviates Lead Toxicity in Mice显示文摘 | Fengwei Tian Qixiao Zhai Jianxin Zhao Xiaoming Liu Gang Wang Hao Zhang Heping Zhang Wei Chen | 2012 | Biological Trace Element Research2012，，1： | 1 |
| 16 | Rudder roll stabilization for ships with generalized predictive control based on fuzzy gain显示文摘 | Gao Qixiao Li An Chen Yongbing | 2009 | 1EEE International Conference on Intelligent Computing and lntelligent Systems2009，，2： | 1 |
| 17 | Anomalous Power-Usage Behavior Detection from Smart Home Wireless Communications显示文摘With the rapid development of Internet of things(IoT)technologies,smart home systems are getting more and more popular in our daily life.Besides provid-ing convenient functionality and tangible benefits,smart home systems expose users to security risks.In this paper,we proposed SHGuard,an anomaly detection approach based on power usage data exposed from wireless commu-nications in the smart home system.SHGuard monitors and collects the electricity-usage data sent from the smart sockets.Based on the collected data,we developed a method to identify/infer the type of device and formally defined the user behavior pattern according to the device event features,e.g.,frequent sequence pattern set,the support degree,the sequence length and the occurrence time of the power changing event.SHGuard extracts and builds the normal behavior pattern during the initialization stage.It continuously infers the smart devices’states by monitoring the electricity usage data and updates the user behavior patterns.Any abnormal behaviors will be detected once the current user behavior pattern deviates from the original pattern.We prototyped our method and evaluated SHGuard using UCI dataset.The experiment results illustrated the efficiency of SHGuard. | Jian Mao Shishi Zhu Jingdong Bian Qixiao Lin Jianwei Liu | 2019 | Journal of Communications and Information Networks2019，4，1： | 1 |
| 18 | Research on the valveless piezoelectric pump with Y-shape pipes显示文摘 | Lu Jizhuang Xai Qixiao | 2007 | Front Mech Eng China2007，2，2： | 1 |
| 19 | A MATHEMATICAL ANALYSIS FOR A DIFFUSIVE EPIDEMIC MODEL WITH CRISS-CROSS DYNAMICS显示文摘In this paper, an initial boundary value problem with homogeneous Neumann boundary condition is studied for a reaction\|diffusion system which models the spread of infectious diseases within two population groups by means of self and criss\|cross infection mechanism. Existence, uniqueness and boundedness of the nonnegative global solution ( u\-1,u\-2,u\-3,u\-4) , existence of the limit of the solution as t→+∞ ,namely,( u\-1,u\-2,u\-3,u\-4)→(u\+*\-1,0,u\+*\-3,0), are proved. | Li Zhengyuan\ Tao Jiyuan\ Ye Qixiao | 1999 | Applied Mathematics(A Journal of Chinese Universities)1999，14，4： | 1 |
| 20 | Effects of vegetarian diet-associated nutrients on gut microbiota and intestinal physiology显示文摘People are increasingly aware of the role of vegetarian diets in modulating human gut microbial abundance and intestinal physiology.A plant-based diet is thought to benefit host health by contributing to establish a diverse and stable microbiome.In addition,microbe-derived metabolites of specific nutrients known to be abundant in vegetarian diets(such as indigestible carbohydrates,arginine,and others) are important to promote effective intestinal immune responses,maintain intestinal barrier function,and protect against pathogens.This review explores the characteristics of the gut microbiome formed by vegetarian diets and the effects of diet-associated nutrients on intestinal microbial abundance.The interactions between the microbe-derived metabolites of vegetarian diet-associated nutrients and intestinal physiology are also discussed. | Wei Xiao Qingsong Zhang Leilei Yu Fengwei Tian Wei Chen Qixiao Zhai | 2022 | Food Science and Human Wellness2022，11，2： | 1 |
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