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| 1 | Pattern and timing of late Cenozoic rapid exhumation and uplift of the Helan Mountain,China显示文摘The Helan Mountain, an intraplate deformation belt in the North China Craton, is located in the northern portion of the China North-South seismic belt, and at the northwestern margin of the Ordos Block. The Cenozoic deformation history of the Helan Mountain is characterized by extension along the eastern Helan Mountain fault (EHSF), resulting in the exhumation and uplift of the Helan Mountain, relative to the rifting of the adjacent Yinchuan Basin. Here we present new apatite fission track (AFT) data from several transects adjacent to the EHSF in the central and northern Helan Mountain. AFT ages from the northern Helan Mountain (Dawukou and Zhengyiguan transects) range from 10 Ma to 89 Ma, whereas AFT ages from the southern Helan Mountain (Suyukou transect) are greater than 71 Ma. The AFT data analysis reveals initiation of rapid uplift and exhumation of the Helan Mountain at 10–12 Ma. Additionally, a plot of the AFT ages versus their mean track length shows a distinctive 'boomerang' pattern indicating that the Helan Mountain experienced a discrete phase of accelerated exhumation beginning at 10-12 Ma. Spatially, AFT samples systematically increase in age away from the EHSF and are consistent with late Cenozoic exhumation that was slow in the southwestern Helan Mountain and rapid in the northeastern Helan Mountain, as well more rapid adjacent to the EHSF and slower away from the EHSF. Obviously, the spatial distribution of late Cenozoic exhumation indicates that normal faulting of the EHSF is related to southwestward tilting and rapid exhumation of the Helan Mountain beginning at 10–12 Ma. The uplift and exhumation of the Helan Mountain was a response to the intensive extension of the northwestern margin of the Ordos Block in the late Cenozoic; this occurred under a regional extensional stress field oriented NW-SE along the Yinchuan-Jilantai-Hetao and the Weihe-Shanxi graben systems adjacent to the Ordos Block. | LIU JianHui ZHANG PeiZhen ZHENG DeWen WAN JinLin WANG WeiTao DU Peng LEI QiYun | 2010 | Science China Earth Sciences2010，53，3： | 23 |
| 2 | Recombinant Newcastle disease virus expressing African swine fever virus protein 72 is safe and immunogenic in mice显示文摘African swine fever(ASF) is a lethal hemorrhagic disease that affects wild and domestic swine. The etiological agent of ASF is African swine fever virus(ASFV). Since the first case was described in Kenya in 1921, the disease has spread to many other countries. No commercial vaccines are available to prevent ASF. In this study, we generated a recombinant Newcastle disease virus(r NDV) expressing ASFV protein 72(p72) by reverse genetics and evaluated its humoral and cellular immunogenicity in a mouse model. The recombinant virus, r NDV/p72, replicated well in embryonated chicken eggs and was safe to use in chicks and mice. The p72 gene in r NDV/p72 was stably maintained through ten passages. Mice immunized with r NDV/p72 developed high titers of ASFV p72 specific Ig G antibody, and had higher levels of Ig G1 than IgG2 a. Immunization also elicited T-cell proliferation and secretion of IFN-γ and IL-4. Taken together, these results indicate that r NDV expressing ASFV p72 might be a potential vaccine candidate for preventing ASF. | Xinxin Chen Jifei Yang Yanhong Ji Edward Okoth Bin Liu Xiaoyang Li Hong Yin Qiyun Zhu | 2016 | Virologica Sinica2016，31，2： | 18 |
| 3 | Dextral strike-slip of Sanguankou-Niushoushan fault zone and extension of arc tectonic belt in the northeastern margin of the Tibet Plateau显示文摘Sanguankou-Niushoushan 差错(SGK-NSSF ) 的运动学的特征具有到弧的延期的理解的大意义在西藏高原的东北边缘的构造的带。用地调查和各种各样的数据收集方法,包括大规模地质的印射,典型地形学的测量,并且沉积阶层标明日期, SGK-NSSF 展出明显的右罢工滑倒特征并且因此不是一个左首的罢工滑倒差错,由以前的研究人员相信了,这被决定。这研究的结果证明地质的边界为古生代,中生代,和新生代时代都被差错右地打乱,与是类似的指责的排水量。在地志的效果的消除以后,差错的最大的罢工滑倒排水量被发现是 | LEI QiYun ZHANG PeiZhen ZHENG WenJun CHAI ChiZhang WANG WeiTao DU Peng YU JingXing | 2016 | Science China Earth Sciences2016，59，5： | 17 |
| 4 | USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA显示文摘圈套(也作为 MITA 知道) 调停天生的抗病毒的发信号和圈套的 ubiquitination 对它的功能关键。然而,圈套的 deubiquitination 过程是不清楚的。这里,我们报导那 USP18 成员 USP20 到连接 K48 的 ubiquitination 从圈套锁住并且支持的 deconjugate 圈套和类型的表示的稳定性我在 DNA 病毒感染以后的 IFN 和 proinflammatory cytokines。USP18 缺乏或 USP20 击倒导致了提高的连接 K48 的 ubiquitination 并且加速了圈套的降级,并且与 DNA 病毒 HSV-1 或各种各样的 DNA ligands 的 transfection 在感染以后损害了下游的基因的 IRF3 和 NF-B 以及正式就职的激活。另外, Usp18 / 老鼠与野类型的同窝出生的人相比更产生 HSV-1 感染。USP18 deubiquitinate 没在 vitro 叮,但是便于 USP20 在 USP18 的酶的活动的一个方式独立人士催化圈套的 deubiquitination。另外,进 Usp18 / MEF 的圈套的宪法恢复了下游的基因和细胞的抗病毒的回答的 HSV-1-induced 表示。我们的调查结果因此以前揭开在调停的 USP18 和 USP20 的 uncharacterized 角色被触发病毒的发信号并且贡献天生的抗病毒的回答的复杂规章的系统的理解。 | Man Zhang Meng-Xin Zhang Qiang Zhang Gao-Feng Zhu Lei Yuan Dong-Er Zhang Qiyun Zhu Jing Yao Hong-Bing Shu Bo Zhong | 2016 | Cell Research2016，26，12： | 12 |
| 5 | Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS显示文摘The activity and stability of the adapter protein MAVS (also known as VISA, Cardif and IPS-1), which critically mediates cellular antiviral responses, are extensively regulated by ubiquitination. However, the process whereby MAVS is deubiquitinated is unclear. Here, we report that the ovarian tumor family deubiquitinase 4 (OTUD4) targets MAVS for deubiquitination. Viral infection leads to the IRF3/7-dependent upregulation of OTUD4 which interacts with MAVS to remove K48-linked polyubiquitin chains, thereby maintaining MAVS stability and promoting innate antiviral signaling. Knockout or knockdown of OTUD4 impairs RNA virus-triggered activation of IRF3 and NF-κB, expression of their downstream target genes, and potentiates VSV replication in vitro and in vivo. Consistently, Cre-ER Otud4fl/fl or Lyz2-Cre Otud4fl/fl mice produce decreased levels of type I interferons and proinflammatory cytokines and exhibit increased sensitivity to VSV infection compared to their control littermates. In addition, reconstitution of MAVS into OTUD4-deficient cells restores virus-induced expression of downstream genes and cellular antiviral responses. Together, our findings uncover an essential role of OTUD4 in virus-triggered signaling and contribute to the understanding of deubiquitination-mediated regulation of innate antiviral responses. | Tianzi Liuyu Keying Yu Liya Ye Zhidong Zhang Man Zhang Yujie Ren Zeng Cai Qiyun Zhu Dandan Lin Bo Zhong | 2019 | Cell Research2019，29，1： | 7 |
| 6 | Investigation of the tribological performance of friction pair for disc brake of drilling rig显示文摘Developing disc-brake pair materials with better performances is a key technique for thedisc brake of drilling rig. Screening experiments were carried out with five different brake-disc ma-terials in pair with two different brake-block materials. The frictional coefficient along with the cor-responding steady coefficient and fluctuating coefficient as well as the wear rate have been dis-cussed. Some conclusions have been achieved: (1) Between the two different cladding materialsbuilt-up on the steel 20~# and 35~# as brake-disc materials, the overall tribological behaviour of theone is better than that of the other. (2) Between the two brake-block composites, the one is betterthan the other. (3) Among these brake pair materials, the tribological behaviours of the second kindof brake-block composite in pair with the second build-up welding material are much better thanthat of the others, therefore, these materials can be selected preliminarily to use in disc brake fordrilling rig. | ZHANG Siwei WANG Xinhua FAN Qiyun LIN Li University of Petroleum, Beijing 102200, China | 2001 | Science China Mathematics2001，44，S1： | 6 |
| 7 | Comprehensive Marine Observing Experiment Based on High-Altitude Large Unmanned Aerial Vehicle(South China Sea Experiment2020 of the “Petrel Project”)显示文摘In collaboration with 12 other institutions, the Meteorological Observation Center of the China Meteorological Administration undertook a comprehensive marine observation experiment in the South China Sea using the Yilong-10 high-altitude large unmanned aerial vehicle(UAV). The Yilong-10 UAV carried a self-developed dropsonde system and a millimeter-wave cloud radar system. In addition, a solar-powered unmanned surface vessel and two drifting buoys were used. The experiment was further supported by an intelligent, reciprocating horizontal drifting radiosonde system that was deployed from the Sansha Meteorological Observing Station, with the intent of producing a stereoscopic observation over the South China Sea. Comprehensive three-dimensional observations were collected using the system from 31 July to2 August, 2020. This information was used to investigate the formation and development processes of Typhoon Sinlaku(2020). The data contain measurements of 21 oceanic and meteorological parameters acquired by the five devices, along with video footage from the UAV. The data proved very helpful in determining the actual location and intensity of Typhoon Sinlaku(2020). The experiment demonstrates the feasibility of using a high-altitude, large UAV to fill in the gaps between operational meteorological observations of marine areas and typhoons near China, and marks a milestone for the use of such data for analyzing the structure and impact of a typhoon in the South China Sea. It also demonstrates the potential for establishing operational UAV meteorological observing systems in the future, and the assimilation of such data into numerical weather prediction models. | Xuefen ZHANG Liangxu LI Rongkang YANG Ran GUO Xia SUN Jianping LUO Hongbin CHEN Daxin LIU Kebing TANG Wenwu PENG Xiaodong HAN Qiyun GUO Xiaoxia LI Xikun FEI | 2021 | Advances in Atmospheric Sciences2021，38，4： | 4 |
| 8 | Cloning,expression and characterization of a nucleoside diphosphate kinase (NDPK) gene from tobacco显示文摘Nucleoside diphosphate kinase (NDPK ) 是维持除了 ATP,在生合成使用的所有(d) NTP 的细胞内部的层次的家务酶。这里,我们报导编码 nucleoside diphosphate kinase (NDPK ) 的全身的 cDNA 用酵母被克隆二混血儿的途径。烟草 NDPK 基因被获得并且指定了为 NtNDPK1。NtNDPK1 是在长度的 704 bp 并且编码一通常认为 148 氨基酸的 16.2 kD 蛋白质。系统发生的分析证明 NtNDPK1 对另外的植物 NDPK 基因高度相应并且作为类型 i (NDPK1 ) 识别。RNA 胶化污点分析证明没有在根的 NtNDPK1 表示的重要差别,起源,离开并且发芽。并且 NtNSPK1 的表示被骆驼毛的织物和木钉导致并且由 NaCl 镇压了,然而并非显著地由 Paraquat 影响了,伤害并且低温度(4 ° C ) 处理, NtNDPK1 可以玩的指示响应不能生活的应力的某个角色。在 vitrophosphorylation,试金证明 NtNDPK1 举办了 autophosphorylation 活动。 | Zhou Qiyun Xie Zongming Zhang Zhigang Cao Yangrong Zhang jinsong Chen Shouyi | 2007 | Progress in Natural Science:Materials International2007，17，8： | 4 |
| 9 | Experimental and analytical study on seismic behavior of steel-concrete multienergy dissipation composite shear walls显示文摘In this paper, a steel-concrete multi-energy dissipation composite shear wall, comprised of steel-reinforced concrete(SRC) columns, steel plate(SP) deep beams, a concrete wall and energy dissipation strips, is proposed. In order to study the multi-energy dissipation behavior and restorability after an earthquake, two stages of low cyclic loading tests were carried out on ten test specimens. In the first stage, test on five specimens with different number of SP deep beams was carried out, and the test lasted until the displacement drift reached 2%. In the second stage, thin SPs were welded to both sides of the five specimens tested in the first stage, and the same test was carried out on the repaired specimens(designated as new specimens). The load-bearing capacity, stiffness, ductility, hysteretic behavior and failure characteristics were analyzed for both stages and the results are discussed herein. Extrapolating from these results, strength calculation models and formulas are proposed herein and simulations using ABAQUS carried out; they show good agreement with the test results. The study demonstrates that SRC columns, SP deep beams, concrete wall and energy dissipation strips cooperate well and play an important role in energy dissipation. In addition, this study shows that the shear wall has good recoverability after an earthquake, and that the welding of thin SP's to repair a deformed wall is a practicable technique. | Dong Hongying Cao Wanlin Wu Haipeng Qiao Qiyun Yu Chuanpeng | 2015 | Earthquake Engineering and Engineering Vibration2015，14，1： | 4 |
| 10 | Assessment of the influence of global dimming on the photosynthetic production of rice based on three-dimensional modeling显示文摘Observations indicate that global radiation reaching the Earth's surface has gradually decreased over the past several decades(i.e.,the 'global dimming' phenomenon),while the fraction of diffuse radiation in global radiation has increased.It has been found that the increase in diffuse fraction significantly increases photosynthetic production in the canopy,but the mechanism has not been clarified.A three-dimensional light distribution model considering the geometry of incident radiation was employed in this study.This model was used to simulate the light distribution and potential photosynthetic production of rice canopy.The results indicate that the potential photosynthetic production of rice significantly increases in response to an increase in the diffuse fraction as long as global radiation does not decline greatly.The 'fertilization effect' of diffuse radiation results from the reduction of leaf area with photosynthetic photon flux density(PPFD) below the light compensation point in response to an increasing diffuse fraction,and an increase in the leaf area with PPFD on the linear part of the light response curve.The increase in the diffuse fraction results in a significant increase in the photosynthetic rate of the upper canopy.High-performance computation is an easy-to-use and economic approach to overcome the computational constraints of the model. | ZHENG BangYou MA YunTao LI BaoGuo GUO Yan DENG QiYun | 2011 | Science China Earth Sciences2011，54，2： | 4 |
| 11 | Systems model-guided rice yield improvements based on genes controlling source, sink, and flow显示文摘A large number of genes related to source, sink,and flow have been identified after decades of research in plant genetics. Unfortunately, these genes have not been effectively utilized in modern crop breeding. This perspective paper aims to examine the reasons behind such a phenomenon and propose a strategy to resolve this situation. Specifically, we first systematically survey the currently cloned genes related to source, sink, and flow;then we discuss three factors hindering effective application of these identified genes, which include the lack of effective methods to identify limiting or critical steps in a signaling network, the misplacement of emphasis on properties, at the leaf, instead of the whole canopy level,and the non-linear complex interaction between source,sink, and flow. Finally, we propose the development of systems models of source, sink and flow, together with a detailed simulation of interactions between them and their surrounding environments, to guide effective use of the identified elements in modern rice breeding. These systems models will contribute directly to the definition of crop ideotype and also identification of critical features and parameters that limit the yield potential in current cultivars. | Pan Li Tiangen Chang Shuoqi Chang Xiang Ouyang Mingnan Qu Qingfeng Song Langtao Xiao Shitou Xia Qiyun Deng Xin-Guang Zhu | 2018 | Journal of Integrative Plant Biology2018，60，12： | 4 |
| 12 | Online recognition of drainage type based on UV-vis spectra and derivative neural network algorithm显示文摘Optimizing sewage collection is important for water pollution control and wastewater treatment plants quality and efficiency improvement.Currently,the urban drainage pipeline network is upgrading to improve its classification and collection ability.However,there is a lack of efficient online monitoring and identification technology.UV-visible absorption spectrum probe is considered as a potential monitoring method due to its small size,reagent-free and fast detection.Because the performance parameters of probe like optic resolution,dynamic interval and signal-to-noise ratio are weak and high turbidity of sewage raises the noise level,it is necessary to extract shape features from the turbidity disturbed drainage spectrum for classification purposes.In this study,drainage network samples were online collected and tested,and four types were labeled according to sample sites and environment situation.Derivative spectrum were adopted to amplify the shape features,while convolutional neural network algorithm was established to conduct nonlinear spectrum classification.Influence of input and network structure on classification accuracy was compared.Original spectrum,first-order derivative spectrum and a combination of both were set to be three different inputs.Artificial neural network with or without convolutional layer were set be two different network structures.The results revealed a convolutional neural network combined with inputs of first and zero-order derivatives was proposed to have the best classification effect on domestic sewage,mixed rainwater,rainwater and industrial sewage.The recognition rate of industrial wastewater was 100%,and the recognition rate of domestic sewage and rainwater mixing system were over 90%. | Qiyun Zhu April Gu Dan Li Tianmu Zhang Lunhong Xiang Miao He | 2021 | Frontiers of Environmental Science & Engineering2021，15，6： | 2 |
| 13 | Study on preparation of heterogeneous polysulfone affinity filter membrane and its sorption properties for Hg2+显示文摘 | Wang Bing Cui Yongfang Du Qiyun | 2003 | Journal of Applied Polymer Science2003，87，： | 1 |
| 14 | Study on positively charged membranes显示文摘 | WANG Yong FAN Yunshuang DU Qiyun | 2001 | J Tianjin Polytoch Univ2001，20，： | 1 |
| 15 | Transcriptional responses of Haemophilus parasuis to iron-restriction stress in vitro显示文摘 | XIE Qiyun JIN Hui LUO Rui | | 0，，06： | 1 |
| 16 | Molecular marker-assisted selection for yield-enhancing genes in the progeny of 9311 using SSR显示文摘 | Liang Fengshan Deng Qiyun Wang Yueguang | 2004 | Euphytica2004，139，： | 1 |
| 17 | Effects of Carbon Black Content on Microwave Absorbing and Mechanical Properties of Linear Low Density Polyethylene/Ethylene-Octene Copolymer/Calcium Carbonate Composites显示文摘 | Qincai Ling Jianzhong Sun Qian Zhao Qiyun Zhou | 2011 | Polymer-Plastics Technology and Engineering2011，，1： | 1 |
| 18 | Synthesis and characterization of a novel liquid crystalline epoxy resin with combining biphenyl and aromatic ester-type mesogenic unit显示文摘 | Cai Zhiqi Sun Jianzhong Zhou Qiyun | 2007 | J Polym Sci A:Polym Chem2007，45，17： | 1 |
| 19 | STUDY ON THE DESALINATION BEHAVIORS OF PA/PSF THIN FILM COMPOSITE显示文摘A polypiperazine amide (PA)/polysulfone (PSF) thin film composite (TFC) was prepared by interfacial polymerization (IP) using a trimesoyl chloride hexane solution as the oil phase and a piperazine aqueous solution as the water phase on a porous polysulfone hollow fiber substrate. Its separating behaviors were investigated systematically to various salts such as NaCl, KCl, Na2SO4, MgCl2, CaCl2 and MgSO4, showing the highest rejection rate to Na2SO4, the second to MgSO4, the third to MgCl2 and CaCl2, and the lowest to KCl, NaCl, being 99%, 98%, 70%, 60%, 15% and 10% respectively. Under an increasing pressure or with time, the rejection rate of the TFC rises to a plateau. To various concentration of the feed, the rejection rate reduced gradually with the higher concentration. | TIAN Guojun ZHANG Yufeng ZHANG Yan DU Qiyun XIAO Changfa GUO Hao | 2006 | Chinese Journal of Reactive Polymers2006，15，2： | 1 |
| 20 | Applicability of nanofihration for the advanced treatment of landfill leaehate显示文摘 | Li Guodong WangWei Du Qiyun | 2010 | Applied Polymer Science2010，，4： | 1 |
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