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| 1 | Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial显示文摘 | Aimery de Gramont Eric Van Cutsem Hans-Joachim Schmoll Josep Tabernero Stephen Clarke Malcolm J Moore David Cunningham Thomas H Cartwright J Randolph Hecht Fernando Rivera Seock-Ah Im Gy?rgy Bodoky Ramon Salazar Frédérique Maindrault-Goebel Einat Shacham- | 2012 | Lancet Oncology2012，，12： | 3 |
| 2 | 9种商业消毒剂对猪2型圆环病毒的杀灭效能测试显示文摘养猪业中常用的许多商业消毒剂,都获得了法国农业部批准。然而对其杀灭增殖初期猪2型圆环病毒(PCV2)的效能却不甚了解。用在法国分离到的PCV2悬液来测试9种商业消毒剂的效能,在20℃下病毒悬液与消毒剂作用30 min后,将该混合液过滤和稀释进行脱毒处理以去除对圆环病毒和猪肾细胞系有害的物质,再经一系列稀释后接种于人工培养的猪肾细胞进行免疫过氧化物酶单层细胞试验(IPMA)测定PCV2的感染性。结果表明,用碘类和苯酚类消毒剂并不能减少病毒滴度。在此着重介绍其他消毒剂效能(病毒滴度减少量≥1.61 log_(10)),其中5种消毒剂:一种含过一硫酸氢钾,另两种含一种季铵盐、一到三种醛、次氯酸钠和氢氧化钠,在标准浓度下或1.5~4倍低于标准浓度时可显著杀灭PCV2;其余两种,其中一种含过一硫酸氢钾,另一种含过氧乙酸和过氧化氢,在标准浓度下或2倍高于标准浓度时也可杀灭PCV2。 | Hélène Martin Marie-Frédérique Le Potier Pierre Maris 杨满军 | 2009 | 今日养猪业2009，，3： | 2 |
| 3 | Sc FOS a prebiotic for synbiotic associations:Recent studies in humans显示文摘 | Céline H Anne W Frédérique R | 2010 | Nutrafoods2010，9，1： | 1 |
| 4 | HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing显示文摘 | Josef Rüschoff Manfred Dietel Gustavo Baretton Susanne Arbogast Axel Walch Geneviéve Monges Marie-Pierre Chenard Frédérique Penault-Llorca Iris Nagelmeier Werner Schlake H. H?fler H. H. Kreipe | 2010 | Virchows Archiv2010，，3： | 1 |
| 5 | HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing显示文摘 | Josef Rüschoff Manfred Dietel Gustavo Baretton Susanne Arbogast Axel Walch Geneviéve Monges Marie-Pierre Chenard Frédérique Penault-Llorca Iris Nagelmeier Werner Schlake H. H?fler H. H. Kreipe | 2010 | Virchows Archiv2010，，3： | 1 |
| 6 | ScFOS a prebiotic forsynbiotic associations: recent studies in humans 显示文摘 | CELINE H ANNE W FRfiD^RIQUE R | 2010 | 9(1): 23-272010，9，1： | 1 |
| 7 | Electrical properties of indium tin oxide thin films grown by pulsed laser deposition显示文摘 | Kim H Horwitz J S Rique A | 1999 | Appl Phys1999，，： | 1 |
| 8 | Structure and expression of the human histamine H4-receptor gene 显示文摘 | Coge F Guenin SP Rique H | 2001 | Biochem Biophys Res Commun2001，284，2： | 1 |
| 9 | Cloning and characterization of the 5 flanking region of the human uncoupling protein 3 (UCP3) gene 显示文摘 | Acina A Rodriguez M Rique H | 1999 | Biochem Biophys Res Commun1999，258，2： | 1 |
| 10 | Guidelines and reality in practica use of and compliance to antidepressants in the treatment of depression:incidence survey in Lorraine and Champagne-Ardenne(France)显示文摘 | Hé rique A Kahn JP | 2009 | Encephale2009，35，1： | 1 |
| 11 | Combined use of high pressure and salt or sodium nitrite to control the growth of endogenous microflora in raw pork meat显示文摘 | Frédérique Duranton Sandrine Guillou Hélène Simonin Romuald Chéret Marie de Lamballerie | 2012 | Innovative Food Science and Emerging Technologies2012，，： | 1 |
| 12 | MADS-box genes in oil palm (Elaeis guineensis):Patterns within the evolution of the SQUAMOSA,DEFICIENS,GLOBOSA,AGAMOUS and SEPALLATA subfamilies显示文摘 | Adam Hélène Jouannic Stefan Morcillo Fabienne Richaud Frédérique Duval Yves Tregear James W | | 0，，： | 1 |
| 13 | Functional characterization of MADS box genes involved in the determination of oil palm flower structure显示文摘 | Adam Hélène Jouannic Stefan Orieux Yves Morcillo Fabienne Richaud Frédérique Duval Yves Tregear James W | | 0，，： | 1 |
| 14 | Cloning and characterization of the 5'flanking region of the human uncoupling protein3 (UCP3) gene显示文摘 | Acin A Rodriguez M Rique H | 1999 | Biochem Biophys Res Commun1999，258，2： | 1 |
| 15 | Human ectonucleotidase-expressing CD25high Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions显示文摘 | Marion Thibaudin Marie Chaix Romain Boidot Frédérique Végran Valentin Derangère Emeric Limagne Hélène Berger Sylvain Ladoire Lionel Apetoh Fran?ois Ghiringhelli | 2016 | OncoImmunology2016，，： | 1 |
| 16 | HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing显示文摘 | Josef Rüschoff Manfred Dietel Gustavo Baretton Susanne Arbogast Axel Walch Geneviéve Monges Marie-Pierre Chenard Frédérique Penault-Llorca Iris Nagelmeier Werner Schlake H. H?fler H. H. Kreipe | 2010 | Virchows Archiv2010，，3： | 1 |
| 17 | Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial显示文摘 | Aimery de Gramont Eric Van Cutsem Hans-Joachim Schmoll Josep Tabernero Stephen Clarke Malcolm J Moore David Cunningham Thomas H Cartwright J Randolph Hecht Fernando Rivera Seock-Ah Im Gy?rgy Bodoky Ramon Salazar Frédérique Maindrault-Goebel Einat Shacham- | 2012 | Lancet Oncology2012，，12： | 1 |
| 18 | Genetic factors for differentiated thyroid cancer in French Polynesia:new candidate loci显示文摘Background:Populations of French Polynesia(FP),where France performed atmospheric tests between 1966 and 1974,experience a high incidence of differentiated thyroid cancer(DTC).However,up to now,no sufficiently large study of DTC genetic factors in this population has been performed to reach definitive conclusion.This research aimed to analyze the genetic factors of DTC risk among the native FP populations.Methods:We analyzed more than 300000 single nucleotide polymorphisms(SNPs)genotyped in 283 DTC cases and 418 matched controls born in FP,most being younger than 15 years old at the time of the first nuclear tests.We analyzed the genetic profile of our cohort to identify population subgroups.We then completed a genome-wide analysis study on the whole population.Results:We identified a specific genetic structure in the FP population reflecting admixture from Asian and European populations.We identified three regions associated with increased DTC risk at 6q24.3,10p12.2,and 17q21.32.The lead SNPs at these loci showed respective p-values of 1.66×10^(−7),2.39×10^(−7),and 7.19×10^(−7) and corresponding odds ratios of 2.02,1.89,and 2.37.Conclusion:Our study results suggest a role of the loci 6q24.3,10p12.2 and 17q21.32 in DTC risk.However,a whole genome sequencing approach would be better suited to characterize these factors than genotyping with microarray chip designed for the Caucasian population.Moreover,the functional impact of these three new loci needs to be further explored and validated. | Monia Zidane Marc Haber Thérèse Truong Frédérique Rachédi Catherine Ory Sylvie Chevillard Hélène Blanché Robert Olaso Anne Boland Éric Conte Mojgan Karimi Yan Ren Constance Xhaard Vincent Souchard Jacques Gardon Marc Taquet André Bouville Jean-François Deleuze Vladimir Drozdovitch Florent de Vathaire Jean-Baptiste Cazier | 2023 | Precision Clinical Medicine2023，6，2： | 0 |
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