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| 1 | Deep seismic reflection profile across the juncture zone between the Tarim Basin and the West Kunlun Mountains显示文摘Fine structures of the crust and upper mantle of the basin-and-range juncture on the northwestern margin of the Qinghai-Tibetan Plateau are first delineated by the deep seismic reflection profile across the juncture zone between the Tarim Basin and the West Kunlun Mountains. Evidence is found for the northward subduction of the northwest marginal lithosphere of the Qinghai-Tibetan Plateau and its collision with Tarim lithosphere beneath the West Kunlun Mountains. The lithosphere image of the face-to-face subduction and collision determines the coupling relationship between the Tarim Basin and the West Kunlun Mountains at the lithosphere scale and reflects the process of continent- continent collision. | GAO Rui HUANG Dongding LU Deyuan QIAN Guihua LI Yingkang KUANG Chaoyang Li Qiusheng LI Pengwu Feng Rujin Guan Ye | 2000 | Chinese Science Bulletin2000，45，24： | 30 |
| 2 | Expression and significance of Musashi-1 in gastric cancer and precancerous lesions显示文摘AIM:To investigate expression of stem cell marker Musashi-1(Msi-1)in relationship to tumorigenesis and progression of intestinal-type gastric cancer(GC).METHODS:Endoscopic biopsy specimens and surgical specimens were obtained,including 54 cases of intestinal-type GC,41 high-grade intraepithelial neoplasia,57low-grade intraepithelial neoplasia,31 intestinal metaplasia,and 36 normal gastric mucosa.Specimens were fixed in 10%paraformaldehyde,conventionally dehydrated,embedded in paraffin,and sliced in 4-μm-thick serial sections.Two-step immunohistochemical staining was used to detect Msi-1 and proliferating cell nuclear antigen(PCNA)expression.Correlation analysis was conducted between Msi-1 and PCNA expression.The relationship between Msi-1 expression and clinicopathological parameters of GC was analyzed statistically.RESULTS:There were significant differences in Msi-1and PCNA expression in different pathological tissues(χ2=15.37,P<0.01;χ2=115.36,P<0.01).Msi-1and PCNA-positive cells were restricted to the isthmus of normal gastric glands.Expression levels of Msi-1and PCNA in intestinal metaplasia were significantly higher than in normal mucosa(U=392.0,P<0.05;U=40.50,P<0.01),whereas there was no significant difference compared to low or high-grade intraepithelial neoplasia.Msi-1 and PCNA expression in intestinaltype GC was higher than in high-grade intraepithelial neoplasia(U=798.0,P<0.05;U=688.0,P<0.01).There was a significantly positive correlation between Msi-1 and PCNA expression(rs=0.20,P<0.01).Msi-1expression in GC tissues was correlated with their lymph node metastasis and tumor node metastasis stage(χ2=12.62,P<0.01;χ2=11.24,P<0.05),but not with depth of invasion and the presence of distant metastasis.CONCLUSION:Msi-1-positive cells may play a key role in the early events of gastric carcinogenesis and may be involved in invasion and metastasis of GC. | Rong-Guang Kuang Yan Kuang Qing-Feng Luo Cheng-Jun Zhou Rui Ji Jian-Wen Wang | 2013 | World Journal of Gastroenterology2013，19，39： | 12 |
| 3 | The formation and evolution of Chepaizi-Mosuowan paleo-uplift and its control on the distributions of sedimentary facies in the Junggar Basin显示文摘The Chepaizi-Mosuowan paleo-uplift is a large-scale uplift stretching across the Junggar Basin formed during the Yanshanian. It has experienced four evolutionary stages: the initial forming stage (J1), the intense development stage (J2+3), the waning and burial stage (K-E), and the tilting and extinction stage (N-Q). The most intense period of activities is the Middle Jurassic. Dur-ing the Early Jurassic, the Chepaizi-Mosuowan paleo-structure was a low amplitude uplift. Because of the subsequent strong uplifting during Middle-Late Jurassic, the Middle and Upper Jurassic were eroded. With the evolution of the Chepaizi-Mosuowan paleo-uplift, the sedimentary pattern of the basin changed, and the paleo-uplift separated the northern depositional systems from those in the south side. As a result, the basin tectonics controlled the distribution and evolution of the depositional systems. During Early Jurassic, while the paleo-uplift was low, its controlling effect on depositional systems was limited and sediments coming from the northwest could reach the central and southern parts of the basin. With the strong uplifting of the Chepaizi-Mosuowan paleo-structure during Middle-Late Jurassic, sediments from the northwest provenance could only deposit in the northern graben of the paleo-uplift. The intense erosion of the Middle-Upper Jurassic also changed the former sedimentary center of the basin into a source area, supplying sediments for grabens on both sides of the paleo-uplift. In the Cretaceous, regional subsidence caused the paleo-uplift to be buried again and subsequently sediments accumulated on top of it. The depositional facies are dominated by fluvial in the Early Cretaceous and shallow lacustrine to deltaic in the Late Cretaceous. In the history of the long-lasting development of this paleo-uplift, large-scale erosions of the paleohigh not only provided sufficient sediments to the center of the Junggar Basin, but also created favorable conditions for the formation of various subtle traps such as lithologic and stratigraphic traps. | JI YouLiang ZHOU Yong KUANG Jun WAN Lu ZHANG Rui LU ChunHong | 2010 | Science China Earth Sciences2010，53，6： | 10 |
| 4 | A New Distributed Localization Scheme for Wireless Sensor Networks显示文摘在无线传感器网络(WSN ) 的节点本地化是被对待一功能目标在纸从一个新奇观点追踪双。与在 WSN 的传统的追踪问题不同,使用静态的地点商品节点估计动人的目标,活动节点被用来帮助未知节点精确地发现他们的位置。一个新节点本地化计划虚拟烽火精力比率本地化(VB-ERL ) 和它为 WSN 的精炼被介绍。在计划,活动节点基于 Gauss-Markov 活动性模型搬到监视者地并且周期性地广播信息包。每个静态的未知节点在它的察觉到的范围收到虚拟烽火和精力,并且由发现一套超球面的交叉估计它的地点。模拟结果证明建议计划是有效的。 | KUANG Xing-Hong SHAO Hui-He FENG Rui | 2008 | 自动化学报2008，34，3： | 7 |
| 5 | CGE model-based analysis of the neutralized hybrid carbon policy and its decomposed effects on economic growth,carbon reduction,and energy utilization costs显示文摘The hybrid policy is a flexible policy tool that combines features of carbon trading and carbon taxation.Its economic and environmental effects under China's background are still not studied in detail.Given the exogenous carbon reduction targets,carbon prices,and carbon tax-rates,by computable general equilibrium modeling methods and factor decomposition methods,this article investigates direct and cascaded effects of the hybrid policy on economic growth,energy utilization,and carbon emission on the national level and the sector level,with China's national input-output data-set.Stepwisely,policy scenarios with irrational estimated results are selectively excluded based on comprehensive evaluation among economic,carbon reduction and other policy targets.As a result,against national economic conditions in 2007,the hybrid policy,with a carbon reduction target of -10%,a carbon tax-rate of around $10,and a ceiling carbon price of $40,is highly recommended,because of its significant lower economic loss,lower energy utilization cost,and practical robustness against fluctuation of energy market and carbon market.Furthermore,by decomposition analysis,carbon reduction-related costs are decomposed into a direct part that includes carbon allowance price and carbon tax,and an indirect part as the energy price incremental induced by direct carbon costs.Gross carbon reduction may be decomposed into three parts such as energy intensity,economic scale,and technical progress.And,carbon taxation is the main policy tool that stimulates to improve the energy efficiency. | Rui Sun Dan Kuang | 2015 | Chinese Journal of Population,Resources and Environment2015，13，1： | 7 |
| 6 | Divergent Projection Patterns Revealed by Reconstruction of Individual Neurons in Orbitofrontal Cortex显示文摘The orbitofrontal cortex(OFC)is involved in diverse brain functions via its extensive projections to multiple target regions.There is a growing understanding of the overall outputs of the OFC at the population level,but reports of the projection patterns of individual OFC neurons across different cortical layers remain rare.Here,by combining neuronal sparse and bright labeling with a whole-brain florescence imaging system(fMOST),we obtained an uninterrupted three-dimensional whole-brain dataset and achieved the full morphological reconstruction of 25 OFC pyramidal neurons.We compared the wholebrain projection targets of these individual OFC neurons in different cortical layers as well as in the same cortical layer.We found cortical layer-dependent projections characterized by divergent patterns for information delivery.Our study not only provides a structural basis for understanding the principles of laminar organizations in the OFC,but also provides clues for future functional and behavioral studies on OFC pyramidal neurons. | Junjun Wang Pei Sun Xiaohua Lv Sen Jin Anan Li Jianxia Kuang Ning Li Yadong Gang Rui Guo Shaoqun Zeng Fuqiang Xu Yu-Hui Zhang | 2021 | Neuroscience Bulletin2021，37，4： | 5 |
| 7 | Effect analysis of carbon trading on Economy-Energy-Environment system and calculation of reasonable carbon price intervals显示文摘This paper constructs a 4-lier computable general equilibrium model which includes such modules as modeling carbon emission constraints and carbon trading(CT),and incorporates the cost of carbon emissions into constant elasticity of substitute production function.Under scenario settings under different carbon abatement targets,based on 2007 national social accounting matrix and related statistical data about energy consumption and carbon emission,effects on economic outputs,energy consumption,and carbon abatement are estimated and analyzed at both macro and sector level.By calculating selected novel indicators that compromise between macroeconomic opportunity cost and achievable carbon abatement,reasonable carbon price intervals are given for enhancing the robustness and liquidity of carbon market.Further,by decomposition and share-weighted methods,expected carbon abatement and energy price are measured and analyzed in details.Some results are meaningful for fundamental design of the future carbon market.Given constant energy utilization and carbon abatement technologies at the macro level,the higher the carbon price the more actual carbon abatement;the more gross domestic product loss,the less energy consumption.Accwding to the overall situation estimated for 2007 in China,the advice given is to introduce a carbon abatement target rate(R_c)of-10%,which is helpful to make carbon market stable against unexpected carbon price shocks between[6.9,35]/tC with less economic loss.According to Kaya decomposition,after introduction of carbon pricing,carbon abatement is mainly contributed by the effects of energy intensity(EI)and technical progress.Further,CT may help reduce energy consumption and induce transformation to a low-carbon energy structure.At the sector level,the introduction of CT could induce economic recession in all sectors,especially energy.However,the overall economic structure remains unchanged to some extent.CT will help reduce energy consumption in all sectors,especially energy.Overall utilization costs of the energy composite can be divided in two,market price and carbonrelated costs.Carbon-related costs mainly contribute to variation in the utilization cos of the energy composite;carbon pricing may help non-energy sectors achieve sufficient carbon abatement by pushing up energy utilization cost.However,despite achievable carbon abatement by the energy sector being relatively high,induced by carbon pricing,there is still significant potential for other incentive policies to stimulate further abatement,such as energy resources taxation and transportation fuel taxation,especially in the sectors of coal and transportation.Finally,some advice is proposed in regard to policy decisions and further research. | Rui Sun Dan Kuang Dongqin Chang | 2015 | Chinese Journal of Population,Resources and Environment2015，13，2： | 5 |
| 8 | Olfactory responses of Aphidius gifuensis to odors of host plants and aphid-plant complexes显示文摘到从二主人植物(Nicotiana tabacum 和 Brassica 马来麝 ssp ) 和他们有二个主人蚜虫(Myzus persicae 和 Lipaphis erysimi ) 的不同群袭层次的建筑群的气味的 Aphidius gifuensis 的嗅觉的回答分别地在 olfactometer 被检验。结果显示出那女 A。gifuensis 没对 undamaged 的气味作出回应或机械地损坏主人植物,但是显著地对蚜虫 / 植物建筑群的气味作出回应。而且,一。gifuensis 对两 M 的气味显著地作出回应。persicae 和 L。erysimi/plant 建筑群当主人植物被蚜虫的高水平大批出没于时,建议导致蚜虫的 volatiles 的那数量能为吸引 A 是重要的。gifuensis。当在蚜虫 / 植物建筑群之间测试了时,一。gifuensis 没为任何一个建筑群显示出它的偏爱。A 的效率。对在田野的蚜虫的 gifuensis 能被使用它的嗅觉的反应到蚜虫 / 植物建筑群潜在地改进。 | Song Yang Rui Xu Shuo-Yuan Yang Rong-Ping Kuang | 2009 | Insect Science2009，16，6： | 4 |
| 9 | Low-Complexity Joint Channel Estimation and Symbol Detection for OFDMA Systems显示文摘In this paper,we propose a joint channel estimation and symbol detection(JCESD)algorithm relying on message-passing algorithms(MPA)for orthogonal frequency division multiple access(OFDMA)systems.The channel estimation and symbol detection leverage the framework of expectation propagation(EP)and belief propagation(BP)with the aid of Gaussian approximation,respectively.Furthermore,to reduce the computation complexity involved in channel estimation,the matrix inversion is transformed into a series of diagonal matrix inversions through the Sherman-Morrison formula.Simulation experiments show that the proposed algorithm can reduce the pilot overhead by about 50%,compared with the traditional linear minimum mean square error(LMMSE)algorithm,and can approach to the bit error rate(BER)performance bound of perfectly known channel state information within 0.1 dB. | Rui Xin Zuyao Ni Sheng Wu Linling Kuang Chunxiao Jiang | 2019 | China Communications2019，16，7： | 4 |
| 10 | Ionic thermal up-diffusion in nanofluidic salinity-gradient energy harvesting显示文摘Advances in nanofabrication and materials science give a boost to the research in nanofluidic energy harvesting.Contrary to previous efforts on isothermal conditions,here a study on asymmetric temperature dependence in nanofluidic power generation is conducted.Results are somewhat counterintuitive.A negative temperature difference can significantly improve the membrane potential due to the impact of ionic thermal up-diffusion that promotes the selectivity and suppresses the ion-concentration polarization;especially at the low-concentration side,which results in dramatically enhanced electric power.A positive temperature difference lowers the membrane potential due to the impact of ionic thermal down-diffusion,although it promotes the diffusion current induced by decreased electrical resistance.Originating from the compromise of the temperature-impacted membrane potential and diffusion current,a positive temperature difference enhances the power at low transmembrane-concentration intensities and hinders the power for high transmembrane-concentration intensities.Based on the system’s temperature response,we have proposed a simple and efficient way to fabricate tunable ionic voltage sources and enhance salinity-gradient energy conversion based on small nanoscale biochannels and mimetic nanochannels.These findings reveal the importance of a long-overlooked element-temperature-in nanofluidic energy harvesting and provide insights for the optimization and fabrication of high-performance nanofluidic power devices. | Rui Long Zhengfei Kuang Zhichun Liu Wei Liu | 2019 | National Science Review2019，6，6： | 4 |
| 11 | Spirulina platensis aqueous extracts ameliorate colonic mucosal damage and modulate gut microbiota disorder in mice with ulcerative colitis by inhibiting inflammation and oxidative stress显示文摘Ulcerative colitis(UC)is a chronic and recurrent inflammatory bowel disease(IBD)that has become a major gastroenterologic problem during recent decades.Numerous complicating factors are involved in UC development such as oxidative stress,inflammation,and microbiota disorder.These factors exacerbate damage to the intestinal mucosal barrier.Spirulina platensis is a commercial alga with various biological activity that is widely used as a functional ingredient in food and beverage products.However,there have been few studies on the treatment of UC using S.platensis aqueous extracts(SP),and the underlying mechanism of action of SP against UC has not yet been elucidated.Herein,we aimed to investigate the modulatory effect of SP on microbiota disorders in UC mice and clarify the underlying mechanisms by which SP alleviates damage to the intestinal mucosal barrier.Dextran sulfate sodium(DSS)was used to establish a normal human colonic epithelial cell(NCM460)injury model and UC animal model.The mitochondrial membrane potential assay 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)and staining with Annexin V-fluorescein isothiocyanate(FITC)/propidium iodide(PI)and Hoechst 33258 were carried out to determine the effects of SP on the NCM460 cell injury model.Moreover,hematoxylin and eosin(H&E)staining,transmission electron microscopy(TEM),enzyme-linked immunosorbent assay(ELISA),quantitative real-time polymerase chain reaction(qPCR),western blot,and 16S ribosomal DNA(rDNA)sequencing were used to explore the effects and underlying mechanisms of action of SP on UC in C57BL/6 mice.In vitro studies showed that SP alleviated DSS-induced NCM460 cell injury.SP also significantly reduced the excessive generation of intracellular reactive oxygen species(ROS)and prevented mitochondrial membrane potential reduction after DSS challenge.In vivo studies indicated that SP administration could alleviate the severity of DSS-induced colonic mucosal damage compared with the control group.Inhibition of inflammation and oxidative stress was associated with increases in the activity of antioxidant enzymes and the expression of tight junction proteins(TJs)post-SP treatment.SP improved gut microbiota disorder mainly by increasing antioxidant enzyme activity and the expression of TJs in the colon.Our findings demonstrate that the protective effect of SP against UC is based on its inhibition of pro-inflammatory cytokine overproduction,inhibition of DSS-induced ROS production,and enhanced expression of antioxidant enzymes and TJs in the colonic mucosal barrier. | Jian WANG Liqian SU Lun ZHANG Jiali ZENG Qingru CHEN Rui DENG Ziyan WANG Weidong KUANG Xiaobao JIN Shuiqing GUI Yinghua XU Xuemei LU | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，6： | 3 |
| 12 | Controlling mine pressure by subjecting high-level hard rock strata to ground fracturing显示文摘When mining extra-thick coal seams,the main cause of strong ground pressure are the high-level thick and hard strata,but as yet there is no active and effective control technology.This paper proposes the method of subjecting hard roofs to ground fracturing,and physical simulation is used to study the control effect of ground fracturing on the strata structure and energy release.The results show that ground fracturing changes the structural characteristics of the strata and reduces the energy release intensity and the spatial extent of overburden movement,thereby exerting significant control on the ground pressure.The Datong mining area in China is selected as the engineering background.An engineering test was conducted on site by ground horizontal well fracturing,and a 20-m-thick hard rock layer located 110 m vertically above the coal seam was targeted as the fracturing layer.On-site microseismic monitoring shows that the crack propagation length is up to 216 m and the height is up to 50 m.On-site mine pressure monitoring shows that(1)the roadway deformation is reduced to 100 mm,(2)the periodic weighting characteristics of the hydraulic supports are not obvious,and(3)the ground pressure in the working face is controlled significantly,thereby showing that the ground fracturing is successful.Ground fracturing changed the breaking characteristics of the high-level hard strata,thereby helping to ameliorate the stress concentration in the stope and providing an effective control approach for hard rock. | Rui Gao Tiejun Kuang Yanqun Zhang Wenyang Zhang Chunyang Quan | 2021 | International Journal of Coal Science & Technology2021，8，6： | 2 |
| 13 | Preparation and evaluation of duloxetine hydrochloride enteric-coated pellets with different enteric polymers显示文摘The main purpose of the present study was to prepare duloxetine hydrochloride(DXH) entericcoated pellets using different enteric polymers. Three layers(drug-loaded layer, barrier layer,and enteric-coated layer) were applied to the inert core pellets, successively. The optimal formulation was manufactured by employing suspension layering method in fluidized bed processor(FBP) with varieties of enteric polymers like Aqoat? AS-LF, Eudragit? L30D55 and HPMCP-HP55. The prepared pellets were measured for physical characterization and the in vitro dissolution profile. Scanning electron microscopy(SEM) was conducted to observe the morphology of pellets, and different kinetic models were applied to analyze the release mechanism of Cymbalta? and home-made pellets. The coating weight gain of enteric-coated layer containing Eudragit? L30D55, Aqoat? AS-LF and HP-55 were determined to be 35%, 26% and 24%, respectively. The similarity factors(f2) of self-made capsules with above polymers and commercially available capsules(Cymbalta?) were above 50 in the dissolution medium of pH 6.8 phosphate buffer solution(PBS). SEM figures showed the smooth surfaces of selfprepared pellets using Eudragit? L30D55 and Aqoat? AS-LF, whereas rough surface was found in the HP-55 pellets at day 0, and an impurity was appearing in the condition of 40 ℃/75% relative humidity for 1 month. In conclusion, the pellets prepared by utilizing Eudragit? L30D55 and Aqoat?AS-LF were the optimal preparations based on the dissolution profile and stability. | Chen Kuang Yinghua Sun Bing Li Rui Fan Jing Zhang Yumin Yao Zhonggui He | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，3： | 1 |
| 14 | A lightweight target tracking scheme using wireless sensor network 显示文摘 | KUANG X H RUI F SHAO H H | 2008 | Measurement Science and Technology2008，19，2： | 1 |
| 15 | Mechanical properties and size stability of wheat straw and recycled LDPE composites coupled by waterborne coupling agents显示文摘 | Kuang Xuan Kuang Rui Zheng Xiaodong | 2010 | Carbohydrate Polymers2010，80，： | 1 |
| 16 | Profile-based string kernels for remote homology detection and motif extraction显示文摘 | KUANG Rui IE E WANG Ke | 2005 | Journal of Bioinformatics and Computational Biology2005，3，3： | 1 |
| 17 | A lightweight target tracking scheme using wireless sensor network显示文摘 | Kuang X H Rui F Shao H H | 2008 | Measurement Science and Technology2008，19，2： | 1 |
| 18 | Naturally Derived Anti-Inflammatory Compounds from Chinese Medicinal Plants显示文摘 | Qiuhong Wang Haixue Kuang Yang Su Yanping Sun Jian Feng Rui Guo Kelvin Chan | 2012 | Journal of Ethnopharmacology2012，，： | 1 |
| 19 | Mechanical properties and size stability of wheat straw and recycled LDPE composites coupled by waterborne coupling agents 显示文摘 | Xuan Kuang Rui Kuang Xiaodong Zheng | 2010 | Carbohydrate Polymers2010，，80： | 1 |
| 20 | Hierarchical Canonical Correlation Analysis Reveals Phenotype,Genotype,and Geoclimate Associations in Plants显示文摘The local environment of the geographical origin of plants shaped their genetic variations through environmental adaptation.While the characteristics of the local environment correlate with the genotypes and other genomic features of the plants,they can also be indicative of genotype-phenotype associations providing additional information relevant to environmental dependence.In this study,we investigate how the geoclimatic features from the geographical origin of the Arabidopsis thaliana accessions can be integrated with genomic features for phenotype prediction and association analysis using advanced canonical correlation analysis(CCA).In particular,we propose a novel method called hierarchical canonical correlation analysis(HCCA)to combine mutations,gene expressions,and DNA methylations with geoclimatic features for informative coprojections of the features.HCCA uses a condition number of the cross-covariance between pairs of datasets to infer a hierarchical structure for applying CCA to combine the data.In the experiments on Arabidopsis thaliana data from 1001 Genomes and 1001 Epigenomes projects and climatic,atmospheric,and soil environmental variables combined by CLIMtools,HCCA provided a joint representation of the genomic data and geoclimate data for better prediction of the special flowering time at 10°C(FT10)of Arabidopsis thaliana.We also extended HCCA with information from a protein-protein interaction(PPI)network to guide the feature learning by imposing network modules onto the genomic features,which are shown to be useful for identifying genes with more coherent functions correlated with the geoclimatic features.The findings in this study suggest that environmental data comprise an important component in plant phenotype analysis.HCCA is a useful data integration technique for phenotype prediction,and a better understanding of the interactions between gene functions and environment as more useful functional information is introduced by coprojections of multiple genomic datasets. | Raphael Petegrosso Tianci Song Rui Kuang | 2020 | Plant Phenomics2020，2，1： | 1 |
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