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| 1 | Relationship among plasma endothelin, calcitonin gene-related peptide and blood flow rate of bilateral vertebral arteries in patients with cervical vertigo显示文摘Objective: To investigate the relationship among plasma endothelin(ET), calcitonin gene-related peptide(CGRP) and blood flow rate of bilateral vertebral arteries in patients with cervical vertigo(CV) and to assess the effect of ET and CGRP on the onset of CV. Methods:The concentration of ET and CGRP in 64 patients with CV and 30 controls was determined by radioimmunity method. The average blood flow velocity (Vm) of bilateral vertebral arteries was detected by Transcranial Doppler(TCD). Results:Plasma concen- tration of ET(91.48± 9.08 pg/ml) and ET/CGRP ratio value(2.88± 0.52) in vertebrobasilar arteriospasm group were both higher than those in vertebrobasilar non-arteriospasm group and in controls, while CGRP concentration(30.66± 6.05 pg/ml) in vertebrobasilar arteriospasm group was lower than that in vertebrobasilar non-arteriospasm group and controls respectively. The Vm of bilateral verte- bral arteries in vertebrobasilar arteriospasm group(67.97± 11.64 cm/s ) was higher than that in vertebrobasilar non-arteriospasm group and controls respectively, having a positive correlation with ET concentration and ET/CGRP ratio value(r1=0.52, P < 0.05; r2=0.59, P < 0.05), but a negative correlation with CGRP concentration(r3=-0.54, P < 0.05). There was no significant difference in ET and CGRP concentration, ET/CGRP ratio value and the Vm of bilateral vertebral arteries between vertebrobasilar non-arteriospasm group and the control group. Conclusion: All the results indicate that ET and CGRP are possibly the most important substance factors at the onset of CV with vertebrobasilar arteriospasm, and their imbalance of regulating vertebrobasilar arterial contraction and relaxation may play an important role in the onset of CV with vertebrobasilar arteriospasm. | Jiajun Wei Jinzhi Xu Suming Zhang | 2008 | Journal of Nanjing Medical University2008，22，3： | 3 |
| 2 | Morphology of the ascending aorta: a study on 114 Chinese patients显示文摘Purpose: This study aimed to investigate the morphological characteristics of ascending aortic dissection in detail. Materials and Methods: The ascending aorta was morphologically assessed in a consecutive series of patients between January 2009 and October 2014. A new assessment and evaluation method was used to describe 114 patients with ascending aortic dissection. Results: A large difference was found in the degree of curvature between the ascending aorta with and without dissection. The shape of the former was straighter and steeper(control group R, 47.46 ± 6.40 mm; experimental group R, 59.70 ± 10.27 mm, P < 0.001). In the case of aortic dissection involving the valves, the proximal edge of the first entry was obviously close to the aortic sinus. The orientation of the entries was mainly around the 10 o'clock and 1–2 o'clock positions, and most of their shapes were fusiform(111; 70.02%). The distance of the distal extending dissection was associated with cases involving the branch arteries(involving three branches 441.40 ± 101.13 mm vs 159.85 ± 131.86 mm in others, P < 0.001). Conclusion: The morphological features of the ascending aorta after dissection and the correlations among dissections, entries, and related factors were found. | Lei Liu Wei Wang Qingsheng Lu Zaiping Jing Suming Zhang Bing Xu | 2018 | Journal of Interventional Medicine2018，1，1： | 3 |
| 3 | Comparative proteomic analysis of a Haemophilus parasuis SC096 mutant deficient in the outer membrane protein P5显示文摘 | Bin Zhang Chenggang Xu Suming Zhou Saixiang Feng Lingyun Zhang Yanbin He Ming Liao | 2011 | Microbial Pathogenesis2011，，2： | 1 |
| 4 | Structure-function relationship of bifunctional scorpion toxin BmBKTxl显示文摘作为在两条大传导力 Ca 2+-activated K + 隧道(放射性元素) 和 duc t 上的小 c 上活跃的首先识别的蝎子毒素 n c e Ca 2+-activated K + 隧道(SK ) , BmBKTx1 被建议了为二个目标有二张分开的功能的脸。调查这个假设,二两倍异种, K21A-Y30A 和 R9A-K11A,和野类型的毒素在 Escherichia 关口 i 被表示。recombinant 毒素为功能的试金在蟑螂放射性元素和老鼠 SK2 隧道上被测试。变异的 K21A-Y30A 在放射性元素上有功能的戏剧的损失,但是在 SK 上保留了它的功能。变异的 R9A-K11A 没在放射性元素或 SK 上失去功能。这些数据支持二个功能脸的假设并且显示 BK 脸在 C 终端 β-sheet 上。 | Suming Wang Lijun Huang Dieter Wicher Chengwu Chi Chenqi Xu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，11： | 1 |
| 5 | The role of galU and galE of Haemophilus parasuis SC096 in serum resistance and biofilm formation显示文摘 | Yi Zou Saixiang Feng Chenggang Xu Bin Zhang Suming Zhou Lingyun Zhang Xianhui He Jingyi Li Zhen Yang Ming Liao | 2012 | Veterinary Microbiology2012，，： | 1 |
| 6 | Association be- tween FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China 显示文摘 | XueQing Wu SuMing Xu JunFen Liu | 2014 | J Assist Reprod Genet2014，31，： | 1 |
| 7 | Unique crystallization behavior of poly( l -lactide)/poly( d -lactide) stereocomplex depending on initial melt states显示文摘 | Yong He Ying Xu Jia Wei Zhongyong Fan Suming Li | 2008 | Polymer2008，，26： | 1 |
| 8 | Involvement of lipooligosaccharide heptose residues of Haemophilus parasuis SC096 strain in serum resistance, adhesion and invasion显示文摘 | Chenggang Xu Lingyun Zhang Bin Zhang Saixiang Feng Suming Zhou Jingyi Li Yi Zou Ming Liao | 2012 | The Veterinary Journal2012，，： | 1 |
| 9 | Enhanced adherence to and invasion of PUVEC and PK-15 cells due to the overexpression of RfaD, ThyA and Mip in the Δ ompP2 mutant of Haemophilus parasuis SC096 strain显示文摘 | Bin Zhang Chenggang Xu Lingyun Zhang Suming Zhou Saixiang Feng Yanbin He Ming Liao | 2012 | Veterinary Microbiology2012，，： | 1 |
| 10 | The outer membrane protein P2 (OmpP2) of Haemophilus parasuis induces proinflammatory cytokine mRNA expression in porcine alveolar macrophages显示文摘 | Suming Zhou Xianhui He Chenggang Xu Bing Zhang Saixiang Feng Yi Zou Jingyi Li Ming Liao | 2013 | The Veterinary Journal2013，，： | 1 |
| 11 | Screening oligonucleotide sequences for silver staining and D-galactose visual detection using RCA silver staining in a tube显示文摘Oligonucleotides 为强烈染色银的重复序列被屏蔽。一个聚类 AG 的嘌呤序列显示出强壮的染色,并且染色的密度能被破坏聚类 AG 的顺序的连续性损害。赞成污点的顺序然后在为它的产品察觉卷圆扩大(RCA ) 被采用。一个染色试管的方法为方便、视觉的 RCA 试金被开发。而且由介绍 GalR 进 RCA,没有任何设备, d 半乳糖被与肉眼染色试管的 RCA 检测。大约 10 公里 d 半乳糖能容易被识别,并且 d 半乳糖的察觉与几另外的 monosaccharides 的比较是特定的。 | Ziwei Chen Xuying Duan Hua Wei Suming Tang Chidong Xu Yanlei Li Yifu Guan Guojie Zhao | 2018 | Acta Biochimica et Biophysica Sinica2018，50，5： | 0 |
| 12 | Reprogramming of mouse neural stem cells to induced pluripotent stem cells using Oct4 combined with microRNA显示文摘microRNA is important for maintaining characteristics of embryonic stem cells,and microRNA302a(MiR-302a) has been shown to exert important effects on cell reprogramming.Therefore,the present study used miR294 and miR302a,in combination with Oct4,to induce mouse neural stem cells(NSCs) into induced pluripotent stem(iPS) cells.Following identification of iPS cells,the effects of microRNA on cell reprogramming were analyzed.Results suggested that reprogramming efficiency with Oct4 + miR-294 + miR-302a was 7-fold greater than Oct4 alone(0.1% vs.0.014%).The iPS cells were undifferentiated and positive for alkaline phosphatase,SSEA-1,and Oct4.These findings demonstrated that microRNAs play an important role in cell reprogramming and provide a safe and efficient induction system for cellular reprogramming. | Qiuyue Yan Jie Xu Yanqiang Zhan Zhouping Tang Suming Zhang | 2011 | Neural Regeneration Research2011，6，1： | 0 |
| 13 | Speciation analysis and significance of ecological geochemistry显示文摘 | Yaping WANG Chunxue XU Ziyi AN Suming WANG | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
| 14 | Gene expression of granulosa and cumulus cells: The prospect inpredicting the quality and developmental competence of oocytesin vitro maturation显示文摘In vitro maturation(IVM),a promising assisted reproductive technology(ART),has been evolving in clinical trials and applications.There is a huge potential demand for IVM in clinical practice because it reduces the stimulation of gonadotropins to patients and provides evidence for the safety of neonatal birth.Unfortunately,the maturation rate of oocytes in vitro is not as high as it is in vivo due to a different microenvironment.Moreover,there are still controversies in predicting the developmental capability of oocytes in IVM.The granulosa cells(GCs)and cumulus cells(CCs),closely surrounding the oocytes,play a critical role in oocytes development,while some studies have shown that they can reflect the quality of oocytes.Many studies have been conducted in terms of oocyte quality in transcriptional level in GCs and CCs of mice,Xenopus africanus,and Homo sapiens,which provides important enlightenment for the successful clinical application of IVM.However,no comprehensive reviews about how gene expression profiles affect oocytes quality have been reported.This review aimed to elucidate the gene expression profiles of GCs and CCs that have effects on the quality and developmental competence of oocytes maturation in vitro.And we also put forward a possible idea for ART in the future,integrating all gene expression profiles of GCs and CCs and predicting the quality of the oocytes. | BICHUN ZHAO XUEQING WU YITONG YUAN YUANTAO GAO XIAO LI RUOCHEN DU SUMING XU RUXIN ZHANG CHUNFANG WANG | 2020 | BIOCELL2020，44，4： | 0 |
| 15 | Comparison of rAAV-2-EGFP versus liposome transfection of neural stem cells显示文摘<正>BACKGROUND:At present,a universal method and vector for transfecting enhanced green fluorescent protein(EGFP) into neural stem cells does not exist.The traditional use of liposome to transfect GFP shows low labeling efficiency and short labeling time.However,there is an increasing number of reports in recent years utilizing adeno-associated virus(AAV) transfection of neural stem cells. OBJECTIVE:To compare differences of neural stem cell transfection via rAAV-2-EGFP or liposome, with regard to transfection efficiency,stability,and safety. DESIGN,TIME AND SETTING:A parallel,controlled experiment at a cellular molecular level was performed in the Central Laboratory,Clinical Neuromedicine Research Center,Tongji Medical College,Huazhong University of Science and Technology,between June 2007 and March 2008. MATERIALS:Liposome 2000 was purchased from Invitrogen,USA;rAAV-2-EGFP was offered from Beijing AGTC Gene Technology,China. METHODS:Cerebral cortical cells from embryonic day 12 C57BL/6 mouse embryo were isolated and cultivated,and the logarithmically growing neural stem cells were divided into three groups. Liposome transfection:neural stem cells were transfected with liposome/EGFP plasmid mixture comprising 2μg pcDNA-3.0-EGFP plasmid and 12μg Liposome 2000 in complete culture solution. AAV transfection:neural stem cells were transfected with virus transfection solution comprising rAAV-2-EGFP and complete culture solution at multiplicity of infection = 10~5.Negative control: physiological saline was used instead of virus transfection solution. MAIN OUTCOME MEASURES:At different time points after transfection(36 hours,1 week,2 weeks,1 month,and 6 months),the proportion of green fluorescent cells was quantified under fluorescent microscopy.Transfection efficiency and proliferative activity of the transfected neural stem cells were detected with flow cytometry and 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-diphenytetrazoliumromide, respectively. RESULTS:The neural stem cells began to express green fluorescence 36 hours after transfection with rAAV-2-EGFP.Transfection efficiency reached a peak(61.2%) at 1 week,and was higher than the liposome transfection group(38.7%;P<0.05).Green fluorescence was detectable for 6 months, with no weakness of expression,and rAAV-2-EGFP transfection showed no obvious effects on the proliferation activity of neural stem cells.In the liposome transfection group,green fluorescence was observed after 24 hours and reached a peak at 3 days.Fluorescence expression and proliferation activity disappeared at 2 weeks. CONCLUSION:rAAV-2-EGFP transfection of neural stem cells was superior to liposome transfection. | Yanqiang Zhan Wei Xiong Jie Xu Bo Yin Furong Wang Suming Zhang | 2009 | Neural Regeneration Research2009，4，11： | 0 |
| 16 | Study on model of correlation between chemical element contents in tree rings and tree roots in soil from the south of Beijing显示文摘 | Yaping WANG Chunxue XU Suming WANG Ziyi AN | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
| 17 | Strengthen the Four Confidences:Inheritance and Development of the Spirit of the May 4th Movement显示文摘The spirit of the May 4th Movement has a profound influence on China’s self-confidence in its path,political system,guiding theories,and culture.This spirit,which conceived the choice of socialist path,has become the foundation of confidence in the socialist path with Chinese characteristics.The Marxist theory contained in the spirit is the core of the theoretical self-confidence of socialism;the socialist system bred by the spirit has borne the fruit of confidence in the socialist system with Chinese characteristics;the new culture movement produced by the spirit is the thrust of cultural self-confidence of socialism with Chinese characteristics.Inheriting and developing the spirit of the May Fourth Movement in the new era is conducive to strengthen the Four Confidences. | Cai Yangbo Xu Suming | 2020 | 学术界2020，，12： | 0 |
| 18 | Effects of second-order dispersion of ultrashort laser pulse on stimulated Raman scattering显示文摘The influence of second-order dispersion(SOD)on stimulated Raman scattering(SRS)in the interaction of an ultrashort intense laser with plasma was investigated.More significant backward SRS was observed with the increase of the absolute value of SOD(|ψ2|).The integrated intensity of the scattered light is positively correlated to the driver laser pulse duration.Accompanied by the side SRS,filaments with different angles along the laser propagation direction were observed in the transverse shadowgraph.A model incorporating Landau damping and above-threshold ionization was developed to explain the SOD-dependent angular distribution of the filaments. | Yanqing Deng Dongning Yue Mufei Luo Xu Zhao Yaojun Li Xulei Ge Feng Liu Suming Weng Min Chen Xiaohui Yuan Jie Zhang | 2022 | High Power Laser Science and Engineering2022，10，6： | 0 |
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