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| 1 | CFD-DEM study of effect of bed thickness for bubbling fluidized beds显示文摘The effect of bed thickness in rectangular fluidized beds is investigated through the CFD-DEM simula- tions of small-scale systems. Numerical results are compared for bubbling fluidized beds of various bed thicknesses with respect to particle packing, bed expansion, bubble behavior, solids velocities, and particle kinetic energy. Good two-dimensional (2D) flow behavior is observed in the bed having a thickness of up to 20 particle diameters. However, a strong three-dimensional (3D) flow behavior is observed in beds with a thickness of 40 particle diameters, indicating the transition from 2D flow to 3D flow within the range of 20-40 particle diameters. Comparison of velocity profiles near the walls and at the center of the bed shows significant impact of the front and back walls on the flow hydrodynamics of pseudo-2D fluidized beds. Hence, for quantitative comparison with experiments in pseudo-2D columns, the effect of walls has to be accounted for in numerical simulations. | Tingwen Li Pradeep Gopalakrishnan Rahul Garg Mehrdad Shahnam | 2012 | Particuology2012，10，5： | 14 |
| 2 | Expansion and Mixing Processes of Underexpanded Supercritical Fuel Jets Injection Into Superheated Conditions显示文摘 | WU P K SHAHNAM M KIRKENDALL K | 1995 | Journal of Propulsion and Power1995，15，5： | 1 |
| 3 | Epidemiological aspects of canine visceral leishmaniosis in the Islamic Republic of Iran显示文摘 | Mehdi Mohebali Homa Hajjaran Yazdan Hamzavi Iraj Mobedi Shahnam Arshi Zabih Zarei Behnaz Akhoundi Koroush Manouchehri Naeini Reza Avizeh Mehdi Fakhar | 2005 | Veterinary Parasitology2005，，3： | 1 |
| 4 | An investigation of particleladen flows in an axisymmetric sudden expansion显示文摘 | Shahnam M Morris G J | 1993 | ASME AMD Recent Advances in Mechanics of Structured Continua1993，160，： | 1 |
| 5 | Incidence and age distribution of colorectal cancer in Iran: Results of a population-based cancer registry显示文摘 | Reza Ansari Mahboobeh Mahdavinia Alireza Sadjadi Mehdi Nouraie Farin Kamangar Faraz Bishehsari Hafez Fakheri Shahriar Semnani Shahnam Arshi Mohammad-Javad Zahedi Sodeif Darvish-Moghadam Fariborz Mansour-Ghanaei Alireza Mosavi Reza Malekzadeh | 2005 | Cancer Letters2005，，1： | 1 |
| 6 | A mathematical pro- gramming approach to designing MOS current-mode logic circuits and systems显示文摘 | Shahnam Khabirim MaithamShams | 2005 | Model and Design of Bipolar and MOS Current-Mode Logic2005，，3： | 1 |
| 7 | Prognostic model of survival outcomes in non-small cell lung cancer patients initiated on afatinib: pooled analysis of clinical trial data显示文摘Objective: Several predictors of survival have been identified in EGFR-positive non-small cell lung cancer(NSCLC) patients treated with first generation EGFR inhibitors. Prognostic models of survival outcomes with afatinib have not been evaluated.Methods: A prognostic tool for overall survival(OS)/progression free survival(PFS) based on pre-treatment clinicopathological factors was developed for EGFR-positive advanced NSCLC patients treated with first-line afatinib using penalised regression of individual-participant data from LUX-Lung 3 and 6(n = 468). Favourable, intermediate and poor risk groups were identified and externally validated using LUX-Lung 1(n = 390) and LUX-Lung 2(n = 129) trials that initiated afatinib following previous chemotherapy or EGFR inhibitor treatment.Results: Discriminative performance was good in the development and validation cohorts. For patients treated with first-line afatinib, the median OS for the favourable, intermediate and poor risk groups were > 47.7, 29.3 and 16.4 months, respectively, and the median PFS were 17.3, 13.2 and 8.3 months, respectively. The improvement in median OS with afatinib use compared to chemotherapy was > 12.4 months for the favourable risk group, whereas no OS benefit was apparent for the poor risk group. The improvement in median PFS with afatinib use compared to chemotherapy was 10.2 months for the favourable risk group and 3.2 months for the poor risk group.Conclusions: A prognostic tool was developed and validated to identify favourable, intermediate and poor risk groups for OS/PFS in EGFR-positive advanced NSCLC patients treated with afatinib. The prognostic groups can inform the likely absolute OS/PFS benefit expected from afatinib compared to chemotherapy in first-line treatment. | Ashley M. Hopkins Adel Shahnam Sasha Zhang Chris S. Karapetis Andrew Rowland Michael J. Sorich | 2019 | Cancer Biology & Medicine2019，16，2： | 0 |
| 8 | Development and validation of SuperDEM for non-spherical particulate systems using a superquadric particle method显示文摘This article presents the development and validation of the Superquadric Discrete Element Method(SuperDEM)for non-spherical particle simulation using a superquadric particle method in open-source CFD suite MFiX.A superquadric particle-particle contact algorithm with accelerating and stabilizing strategy was developed.A superquadric particle-arbitrary wall contact algorithm was developed,which enables the simulation in complex geometry.The solver was validated by comparing with experimental data generated in this study or available in the literature.Tests include cylinder contacting with a wall,static packing of M&M chocolate candies in a cylindrical container,static packing of cylinders in a cylindrical container,dynamic angle of repose of cylinders in a rotating drum,and discharging of chocolate candies from a hopper.Besides,MPI parallelization of the solver was implemented and the parallel performance of the solver using MPI was assessed through large-scale simulations of 1 million,10 million,and 100 million particles on up to 6800 cores,which demonstrates that the SuperDEM solver has great potential for industrial-scale systems simulation. | Xi Gao Jia Yu Ricardo J.F.Portal Jean-François Dietiker Mehrdad Shahnam William A.Rogers | 2022 | Particuology2022，20，2： | 0 |
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