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| 1 | Population-based study of DNA image cytometry as screening method for esophageal cancer显示文摘AIM:To explore the DNA image cytometry (DNA-ICM) technique as a primary screening method for esopha-geal squamous precancerous lesions.METHODS:This study was designed as a population-based screening study.A total of 582 local residents aged 40 years-69 years were recruited from Linzhou in Henan and Feicheng in Shandong.However,only 452 subjects had results of liquid-based cytology,DNA-ICM and pathology.The sensitivity and specificity of DNA-ICM were calculated and compared with liquid-based cytology in moderate dysplasia or worse.RESULTS:Sensitivities of DNA-ICM ranging from at least 1 to 4 aneuploid cells were 90.91%,86.36%,79.55% and 77.27%,respectively,which were better than that of liquid-based cytology (75%).Specifici-ties of DNA-ICM were 70.83%,84.07%,92.65% and 96.81%,but the specificity of liquid-based cytology was 91.91%.The sensitivity and specificity of a combination of liquid-based cytology and DNA-ICM were 84.09% and 85.78%,respectively.CONCLUSION:It is possible to use DNA-ICM tech-nique as a primary screening method for esophageal squamous precancerous lesions. | Lin Zhao,Wen-Qiang Wei,Xin-Qing Li,Guo-Qing Wang,Qi Shang,You-Lin Qiao,Department of Cancer Epidemiology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China De-Li Zhao,Department of Epidemiology,Feicheng People’s Hospital,Feicheng 271600,Shandong Province,China Chang-Qing Hao,Department of Endoscopy,Linzhou Cancer Hospital,Linzhou 456500,Henan Province,China Dong-Mei Lin,Qin-Jing Pan,Department of Pathology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China Fu-Hua Lei,Department of Pathology,Feicheng People’s Hospi-tal,Feicheng 271600,Shandong Province,China Jin-Wu Wang,Department of Pathology,Linzhou Cancer Hospi-tal,Linzhou 456500,Henan Province,China | 2012 | World Journal of Gastroenterology2012，18，4： | 15 |
| 2 | EFFECT OF OVERLAPPING TREATMENT ON MICROSTRUCTURE OF LASER-CLAD WC/Ni60A COMPOSITE COATING显示文摘The effect of overlapping treatment on microstructure of laser clad WC/Ni60A composite coating was studied with XRD, SEM, TEM and SAED etc. The results show that during the overlapping treatment the existence of the residual heat and edge angle effect on the substrate has changed the composition and microstructure of the coating by raising the fusion temperature and increasing the dilution degree of the coating. | C.Z. Chen 1,2) , X.D. Liu 3) , S.J. Zhang 4) , D.W. Cui 1) , T.Q. Lei 2) and J.H. Yu 1) 1) College of Material Science and Technology, Shandong University of Technology, Jinan 250061, China 2) College of Material Science and T | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，5： | 6 |
| 3 | Chemical formation and source apportionment of PM_(2.5) at an urban site at the southern foot of the Taihang mountains显示文摘The region along the Taihang Mountains in the North China Plain(NCP) is characterized by serious fine particle pollution. To clarify the formation mechanism and controlling factors, an observational study was conducted to investigate the physical and chemical properties of the fine particulate matter in Jiaozuo city, China. Mass concentrations of the water-soluble ions(WSIs) in PM_(2.5) and gaseous pollutant precursors were measured on an hourly basis from December 1, 2017, to February 27, 2018. The positive matrix factorization(PMF) method and the FLEXible PARTicle(FLEXPART) model were employed to identify the sources of PM_(2.5). The results showed that the average mass concentration of PM_(2.5) was 111 μg/m^(3) during the observation period. Among the major WSIs, sulfate, nitrate, and ammonium(SNA) constituted 62% of the total PM_(2.5) mass, and NO_(3)^(-) ranked the highest with an average contribution of 24.6%. NH_(4)^(+) was abundant in most cases in Jiaozuo. According to chemical balance analysis, SO_(2)-4, NO_(3)^(-), and Cl^(-) might be present in the form of(NH_4)_(2)SO_4, NH_4NO_3, NH_4Cl, and KCl. The liquid-phase oxidation of SO_(2) and NO_(2) was severe during the haze period. The relative humidity and pH were the key factors influencing SO_(4)^(2-) formation. We found that NO_(3)^(-) mainly stemmed from homogeneous gas-phase reactions in the daytime and originated from the hydrolysis of N_(2)O_5 in the nighttime, which was inconsistent with previous studies. The PMF model identified five sources of PM_(2.5) : secondary origin(37.8%), vehicular emissions(34.7%), biomass burning(11.5%), coal combustion(9.4%), and crustal dust(6.6%). | Xiaoyong Liu Mingshi Wang Xiaole Pan Xiyue Wang Xiaolong Yue Donghui Zhang Zhigang Ma Yu Tian Hang Liu Shandong Lei Yuting Zhang Qi Liao Baozhu Ge Dawei Wang Jie Li Yele Sun Pingqing Fu Zifa Wang Hong He | 2021 | Journal of Environmental Sciences2021，33，5： | 5 |
| 4 | Analysis of Amino Acids in a Single Human Red Blood Cell by Capillary Zone Electrophoresis with Intracellular NDA- derivatization and Electrochemical Detection显示文摘A novel method for determination of amino acids in individual human red blood cells has been developed. In this method, the derivatization reagents (NDA and CN-) are introduced into living cells by electroporation. After completion of derivatization, the amino acids in a single cell is determined by capillary zone electrophoresis with end-column amperometric detection. | Qian DONG, Xiao Lei WANG, Lan Lan ZHU, Wen Rui JIN* School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 | 2002 | Chinese Chemical Letters2002，13，7： | 2 |
| 5 | Zeolite-Catalyzed Acetalization Ⅰ. Synthesis of Some Acetals and Ketals through Reaction of Carbonyl Compounds with Ethanediol显示文摘The acetalization of a series of carbonyl compounds with ethanediolwas performed over two self-steaxned HY zeolle catalpsts’ The acetal and ketaiproducts were obtained with high ytelds Espectw, the HY zeollte with highfraxnework Si/A1 ratio was proven to be suitable cataipst for the acetabotion ofunsaturated carbonyl compounds, during which the C =C double bond was | Wei JIANG Yan TIAN Yu Dao MA Qi Long WANG(Department of Chemistry, Shandong University, Jinan 250100)Lei WANG(Department of Pharmacy, Shandong Medical University, Jinan, 250012) | 1997 | Chinese Chemical Letters1997，8，5： | 2 |
| 6 | Λ-Shaped optoelectronic materials based on Trger's base显示文摘Trger's base (TB) is a well-known chiral molecule with rigid concave shape that makes it applicable in different areas such as superamolecular chemistry,molecular recognition,biological labeling,and so on.In this article,we briefly summarize some recent research progress in the optoelectronic properties of novel TB analogues and their applications in optoelectronic field with emphasis on the developments achieved in our group. | YUAN ChunXue,XIN Qian,LIU HuiJun,WANG Lei,JIANG MinHua & TAO XuTang State Key Laboratory of Crystal Materials Shandong University,Jinan 250100,China | 2011 | Science China Chemistry2011，54，4： | 2 |
| 7 | Research on Landscape Planning and Design of Famous Historic and Cultural Sites as Outdoor Sightseeing and Relaxation Spaces——A Case Study of Taiqing Scenic Area in Mount Laoshan,Qingdao City显示文摘Design attributes of famous historic and cultural sites were analyzed,and problems in the present planning and design of these relics were proposed on the basis of fully studying characteristics of outdoor sightseeing and relaxation spaces in famous historic and cultural sites such as disordered route,lack of cultural context and overuse of design formalism.Taiqing Scenic Area in the Mount Laoshan was taken for example to explore design techniques of famous historic and cultural sites.It was stressed that history should be respected,cultural context continued;development properly designed,favorable ecological conditions created;tour routes reasonably designed,tourists' feelings valued;aesthetic principles should be followed,and beauty of scenery depends on moods of viewers.This study was to make the future design of famous historic and cultural sites practical. | LIU Xiaochen,SONG Lei(Qingdao Agriculture University,Qingdao,Shandong 266109,China) | 2012 | Journal of Landscape Research2012，4，7： | 1 |
| 8 | Cross-boundary transport and source apportionment for PM_(2.5) in a typical industrial city in the Hebei Province,China:A modeling study显示文摘Cross-boundary transport of air pollution is a difficult issue in pollution control for the North China Plain.In this study,an industrial district(Shahe City)with a large glass manufactur-ing sector was investigated to clarify the relative contribution of fine particulate matter(PM_(2.5))to the city's high levels of pollution.The Nest Air Quality Prediction Model System(NAQPMS),paired with Weather Research and Forecasting(WRF),was adopted and applied with a spatial resolution of 5 km.During the study period,the mean mass concentrations of PM_(2.5),SO_(2),and NO_(2)were observed to be 132.0,76.1,and 55.5μg/m^(3),respectively.The model reproduced the variations in pollutant concentrations in Shahe at an acceptable level.The simulation of online source-tagging revealed that pollutants emitted within a 50-km radius of downtown Shahe contributed 63.4%of the city's total PM_(2.5)concentration.This contribu-tion increased to 73.9±21.2%when unfavorable meteorological conditions(high relative hu-midity,weak wind,and low planetary boundary layer height)were present;such conditions are more frequently associated with severe pollution(PM_(2.5)≥250μg/m^(3)).The contribution from Shahe was 52.3±21.6%.The source apportionment results showed that industry(47%),transportation(10%),power(17%),and residential(26%)sectors were the most important sources of PM_(2.5)in Shahe.The glass factories(where chimney stack heights were normally<70 m)in Shahe contributed 32.1%of the total PM_(2.5)concentration in Shahe.With an in-crease in PM_(2.5)concentration,the emissions from glass factories accumulated vertically and narrowed horizontally.At times when pollution levels were severe,the horizontally influ-enced area mainly covered Shahe.Furthermore,sensitivity tests indicated that reducing emissions by 20%,40%,and 60% could lead to a decrease in themass concentration of PM_(2.5) of of 12.0%,23.8%,and 35.5%,respectively. | Xiaoyong Liu Xiaole Pan Jie Li Xi Chen Hang Liu Yu Tian Yuting Zhang Shandong Lei Weijie Yao Qi Liao Yele Sun Zifa Wang Hong He | 2022 | Journal of Environmental Sciences2022，34，5： | 1 |
| 9 | Transport Patterns and Potential Sources of Atmospheric Pollution during the ⅩⅩⅣ Olympic Winter Games Period显示文摘The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the ⅩⅩⅣ Olympic Winter Games(OWG). Transport patterns and potential sources of pollutants in Zhangjiakou(ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM_(2.5) concentration during February in ZJK has increased slightly(28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas(2015–18) to the North China Plain and northern Shanxi Province(NCPS) after 2018.Using CO as an indicator, the relative contributions of the different regions to the receptor site(ZJK) were evaluated based on the source-receptor-relationship method(SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia(CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the ⅩⅩⅣ OWG. | Yuting ZHANG Xiaole PAN Yu TIAN Hang LIU Xueshun CHEN Baozhu GE Zhe WANG Xiao TANG Shandong LEI Weijie YAO Yuanzhe REN Yongli TIAN Jie LI Pingqing FU Jinyuan XIN Yele SUN Junji CAO Zifa WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 10 | Measurement of all electro-elastic constants of lithium tetraborate(Li_2B_4O_7)crystal显示文摘A new approach to determine all the electro-elastic constants of thepiezoelectric crystals in class 4mm has been put forward.As an example,all theconstants of Lithium Tetraborate(Li2B4O7)crystal have been measured bymeans of the approach.The outstanding advantage of the approach is that it on-ly needs to employ in measurement three crystal plates differently oriented. | WANG Jinfeng ZHANG Lei and QIN Zikai(Department of Physics, Shandong University)WANG Hong(Institute of Crystal Materials, Shandong University)HE Dazhen and HO Shaoqin(Institute of Piezoelectrical and Acousto-optical Technology, Sichuan) | 1990 | Chinese Journal of Acoustics1990，9，2： | 1 |
| 11 | Molecular Electrical Conductor Ni(C_3S_5)_2显示文摘The molecular based electrical conductor Ni(C3S5)2 has been prepared and its conductivity has been measured from room temperature down to 60 K. Above 167 K Ni(C3S5)2 exhibits a semiconductive behaviour, below this temperature it turns to exhibit metallic conductivity. Based on a tight-binding energy band calculation, an expression for the number of conducting electrons has been deduced. The calculated conducting activation energy is quite well in accordance with the measuring value. | Hong LEI (Dept. of Electronic Engineering, Shandong University, Jinan 250100, China)Qi FANG and Minhua JIANG (Institute of Crystal Materials, Shandong University, Jinan 250100, China)Yueming SUN (Dept. of Chemistry Southeast University Nanjing 210093, Ch | 1996 | Journal of Materials Science & Technology1996，12，6： | 1 |
| 12 | Newton-conjugate gradient (CG) augmented Lagrangian method for path constrained dynamic process optimization显示文摘In this paper, a Newton-conjugate gradient (CG) augmented Lagrangian method is proposed for solving the path constrained dynamic process optimization problems. The path constraints are simplified as a single final time constraint by using a novel constraint aggregation function. Then, a control vector parameterization (CVP) approach is applied to convert the constraints simplified dynamic optimization problem into a nonlinear programming (NLP) problem with inequality constraints. By constructing an augmented Lagrangian function, the inequality constraints are introduced into the augmented objective function, and a box constrained NLP problem is generated. Then, a linear search Newton-CG approach, also known as truncated Newton (TN) approach, is applied to solve the problem. By constructing the Hamiltonian functions of objective and constraint functions, two adjoint systems are generated to calculate the gradients which are needed in the process of NLP solution. Simulation examples demonstrate the effectiveness of the algorithm. | Qiang ZHANG, Shurong LI, Yang LEI, Xiaodong ZHANG College of Information and Control Engineering, China University of Petroleum (East China), Qingdao Shandong 266555, China | 2012 | 控制理论与应用(英文版)2012，10，2： | 0 |
| 13 | THERMAL CONDUCTIVITY OF Al-Li ALLOY AT CRYOGENIC TEMPERATURES显示文摘THERMALCONDUCTIVITYOFAl-LiALLOYATCRYOGENICTEMPERATURES￥SunDongsheng;LiFengzhao;ShangLei(DepartmentofMaterialsScienceandEngine... | Sun Dongsheng Li engzhao Shang Lei(Department of Materials Science and Engineering,Shandong Univesity of Technology,Jinan 250014) | 1996 | 中国有色金属学会会刊:英文版1996，6，4： | 0 |
| 14 | The Synthesis, Photoconductivity, Photoinduced Charge Transfer, and Other Properties of HEC-TCNQ显示文摘The donor-acceptor complex HEC-TCNQ (HEC=9-hydroxyethylcarbazole;TCNQ = tetracyanoqinodimethane) has been synthesized. Under the illumination of Ar+ laser, the photoinduced charge transfer salt HEC+TCNQ- can be formed with a conductivity of at least one order of magnitude larger than that of HEC-TCNQ. | Qi FANG Hong LEI Dong XU Duo Rong YUAN(Institute of Crystal Materials, Shandong University, Jinan 250100Department of Electronic Engineering, Shandong University, Jinan 250100) | 1997 | Chinese Chemical Letters1997，8，1： | 0 |
| 15 | Refractory black carbon aerosols in rainwater in the summer of 2019 in Beijing:Mass concentration,size distribution and wet scavenging ratio显示文摘Black carbon(BC)aerosols in the atmosphere play a significant role in climate systems due to their strong ability to absorb solar radiation.The lifetime of BC depends on atmospheric transport,aging and consequently on wet scavenging processes(in-cloud and below-cloud scavenging).In this study,sequential rainwater samples in eight rainfall events collected in 2 mm interval were measured by a tandem system including a single particle soot photometer(SP2)and a nebulizer.The results showed that the volume-weighted average(VWA)mass concentrations of refractory black carbon(rBC)in each rainfall event varied,ranging from 10.8 to 78.9μg/L.The highest rBC concentrations in the rainwater samples typically occurred in the first fraction from individual rainfall events.The geometric mean median mass-equivalent diameter(MMD)decreased under precipitation,indicating that rBC with larger sizes was relatively aged and preferentially removed by wet scavenging.A positive correlation(R2=0.73)between the VWA mass concentrations of rBC in rainwater and that in ambient air suggested the important contribution of scavenging process.Additionally,the contributions of in-cloud and below-cloud scavenging were distinguished and accounted for 74%and 26%to wet scavenging,respectively.The scavenging ratio of rBC particles was estimated to be 0.06 on average.This study provides helpful information for better understanding the mechanism of rBC wet scavenging and reducing the uncertainty of numerical simulations of the climate effects of rBC. | Shandong Lei Baozhu Ge Hang Liu Jiannong Quan Danhui Xu Yuting Zhang Weijie Yao Lu Lei Yu Tian Qi Liao Xiaoyong Liu Jie Li Jinyuan Xin Yele Sun Pingqing Fu Junji Cao Zifa Wang Xiaole Pan | 2023 | Journal of Environmental Sciences2023，，10： | 0 |
| 16 | Development and evaluation of an online monitoring single-particle optical particle counter with polarization detection显示文摘We developed a single-particle optical particle counter with polarization detection(SOPC)for the real-time measurement of the optical size and depolarization ratio(defined as the ratio of the vertical component to the parallel component of backward scattering)of atmospheric particles,the polarization ratio(DR)value can reflect the irregularity of the particles.The SOPC can detect aerosol particles with size larger than 500 nm and the maximum particle count rate reaches~1.8×10^(5)particles per liter.The SOPC uses a modulated polarization laser to measure the optical size of particles according to forward scattering signal and the DR value of the particles by backward S and P signal components.The sampling rate of the SOPC was 106#/(sec·channel),and all the raw data were processed online.The calibration curve was obtained by polystyrene latex spheres with sizes of 0.5-10μm,and the average relative deviation of measurement was 3.96% for sub 3μm particles.T-matrix method calculations showed that the DR value of backscatter light at 120°could describe the variations in the aspect ratio of particles in the above size range.We performed insitu observations for the evaluation of the SOPC,the mass concentration constructed by the SOPC showed good agreement with the PM_(2.5)measurements in a nearby state-controlled monitoring site.This instrument could provide useful data for source appointment and regulations against air pollution. | Weijie Yao Xiaole Pan Yu Tian Hang Liu Yuting Zhang Shandong Lei Junbo Zhang Yinzhou Zhang LinWu Yele Sun Zifa Wang | 2024 | Journal of Environmental Sciences2024，，4： | 0 |
| 17 | A Simple Method for Fabrication of Gold Nanoelectrodes显示文摘A facile method has been developed for the fabrication of Au nanoelecrodes (Au NEs). The tip of Au NEs can be controlled within the range from dozens to hundreds of nanometer. | Xiao Lei WANG, Wen Rui JIN* School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 | 2003 | Chinese Chemical Letters2003，14，7： | 0 |
| 18 | CHROMATOGRAPHIC SEPERATION AND PURIFICATION OF HUMAN CHORIONIC GONADOTROPIN显示文摘CHROMATOGRAPHICSEPERATIONANDPURIFICATIONOFHUMANCHORIONICGONADOTROPINWangHaifeng;XuYutai;RenRougli;TangLei;WangHairen(Departme... | Wang Haifeng Xu Yutai Ren Rougli Tang Lei Wang Hairen (Department of Biology, Shandong University, Jinan 250100) | 1995 | Chinese Journal of Reactive Polymers1995，4，1： | 0 |
| 19 | The theoretical study of one-carbon unit transfer with H_2O participation from imidazolidine to dUMP analogue显示文摘The ONIOM quantum mechanics method is used to study the reaction of one-carbon unit transfer from an imidazolidine to 6- aminouracil model with the participation of water molecules.The computation results show that in this reaction the participation of H2O molecule makes the energy barrier lower because of the H-bond interaction. | Chuan Song Qi~(a,*) Wei Li~a Xin Min Wu~a Lei Xu Beijing Institute of Petro-chemical Technology,Beijing 102617,China Da Cheng Feng Institute of Theoretical Chemistry,Shandong University,Jinan 250100,China | 2007 | Chinese Chemical Letters2007，18，9： | 0 |
| 20 | Large second-order optical nonlinearities of s-triazine derivatives: View from micro molecules to macro crystals显示文摘Three s-triazine derivatives have been synthesized and their structures been de-termined. These are Compound I: 2,4-dimethyl-6-(p-N,N-dimethylaminostyryl)-s-triazine (abbre-viated to NMe-1), Compound II: 2,4-dimethyl-6-(p-N,N-diethylaminostyryl)-s-triazine (to NEt-1), and Compound III: 2-methyl-4,6-bis(p-N,N-dimethylaminostyryl)-s-triazine (NMe-2). NMe-1 and NEt-1 molecules belong to the D-π-A type with a one-dimensional charge-transfer character. NMe-1 crystallizes to centrosymmetric P1 space group, while NEt-1 to non-centrosymmetric polar Cc space group with all of the molecular charge-transfer axes taking the same orientation. Under the irradiation of 1064 nm fundamental laser, NEt-1 powder crystals radiate a 2-order harmonic light with an intensity 46.8 times that of urea. The Λ typed NMe-2 molecule, which has a two-dimensional charge-transfer character, crystallizes to polar P21 space group. Its powder crystals exhibit a 2-order harmonic intensity 46.2 times that of urea. The quantum chemical cal-culations and tensor analyses have been carried out to reveal the dependence of the macro 2-order nonlinear optical (NLO) efficiency on the micro 2-order NLO coefficients (β) and on the crystalline packing styles. | FANG Qi1, LEI Hong2, CUI Yuezhi3, HUANG Zhenli4, XUE Gang1 & YU Wentao1 1. State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China 2. School of Information Science and Engineering, Shandong University, Jinan 250100, China 3. Department of Chemical Engineering, Light Industry College of Shandong, Jinan 250100, China 4. Key Laboratory of Biomedical Photonics, Ministry of Education, Huazhong University of Science and Technology, Wuhan 430074, China | 2005 | Science China Chemistry2005，48，3： | 0 |
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