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| 1 | Prevalence of depression in coronary heart disease in China:a systematic review and meta-analysis显示文摘 | Ren Yanping Yang Hui Colette Browning Shane Thomas Liu Meiyan | 2014 | Chinese Medical Journal2014,,16: | 64 |
| 2 | Challenges in the provision of community aged care in China显示文摘Objective:Population ageing in China is a significant challenge for the Chinese government,the society and Chinese people.The dramatic process of population ageing together with social and economic diversity in China has created issues in the availability,equality and sustainability of social and financial support for older people.The aims of this review are to identify the social and economic challenges to the traditional caregiving system in China,and to examine possible solutions to improve the care of older people in China using the framework of ageing in place.Methods:Electronic literature searches were conducted in May and June 2013 using PubMed,CNKI,and MEDLINE.Statistical data and reports were retrieved from the United Nations,the World Health Organisation,the World Bank and National Bureau of Statistics of China.Government policy documents were found through government websites and formal publications.Results:Family-centred care for older people in China is recognised as a cultural tradition in the Chinese community.However,driven by large-scale social,political and economic changes,this model of caring for older people has dynamically changed over the last 50 years.Traditionally the family has been the most important source of social support for older people followed by neighbour support and support from friends.Today family obligations of caring are still centred in a cultural and practical context;however,support from family and children has weakened incrementally.Community-based aged services are absent in most areas,while older people and their families have to pay out-of-pocket expenses for non-residential services.There is a severe shortage of aged care or nursing home resources in China and those that exist are of low quality and expensive.The staff who work in these facilities rarely have any formal training in aged care.In addition,a market approach to the funding of residential aged care has the potential to create a moral hazard due to the poor regulatory control of aged care in China.While the building of residential aged care homes is seen as the solution to the care of older people in China,older people prefer to age in their own homes and expect the restoration of the family care tradition as well as more government support for them to“age in place”.This approach has the potential to be more cost effective than expensive aged care facilities.Conclusion:Given older people’s preferences,ageing in place,with the provision of community services and family support,potentially provides a fair and financially viable approach to promote healthy ageing and supportive care in China.Further studies are required to identify 1)how ageing in place can be supported by a national strategy,2)the financial arrangements required to fund such an approach,and 3)how to train high quality community-based professionals in both rural and urban areas to support the care of older people. | HUI YANG COLETTE BROWNING SHANE THOMAS | 2013 | Family Medicine and Community Health2013,1,2: | 10 |
| 3 | Large-scale synthesis of N-doped carbon capsules supporting atomically dispersed iron for efficient oxygen reduction reaction electrocatalysis显示文摘The large-scale synthesis of platinum-free electrocatalysts for the oxygen reduction reaction(ORR)remains a grand challenge.We report the large-scale production of stable and active ORR electrocatalysts based on iron,an earth-abundant element.A core–shell zeolitic imidazolate framework–tannic acid coordination polymer composite(ZIF-8@K-TA)was utilized as the catalyst precursor,which was transformed into iron atoms dispersed in hollow porous nitrogen-doped carbon capsules(H-Fe-N_(x)-C)through ion exchange and pyrolysis.H-Fe-N_(x)-C fea-tures site-isolated single-atom iron centers coordinated to nitrogen in graphitic layers,high levels of nitrogen doping,and high permeability to incoming gases.Benefiting from these characteristics,H-Fe-N_(x)-C demonstrated efficient electrocatalytic activity(E_(1/2)=0.92 V,vs.RHE)and stability towards the ORR in both alkaline and acidic media.In ORR performance,it surpassed the majority of recently reported Fe-N-C catalysts and the standard Pt/C catalyst.In addition,H-Fe-N_(x)-C showed outstanding tolerance to methanol. | Hui Yang Yanfang Liu Xiaolu Liu Xiangke Wang He Tian Geoffrey I.N.Waterhouse Paul E.Krugere Shane GTelfer Shengqian Ma | 2022 | eScience2022,2,2: | 4 |
| 4 | 全科医学中的心理健康病案研究(二十六)--抑郁与恶性肿瘤显示文摘中国全科医学杂志与澳大利亚Monash大学和Melbourne大学的全科医学专家和心理学专家在2012年伊始共同推出“全科医学中的心理健康病案研究”学术专栏,该专栏由澳大利亚的几位专家轮流撰写,以介绍社区常见的心理问题及其解决方法为主要内容,获得了读者的广泛好评。今年我刊将继续该学术专栏的登载,以推动我国社区心理学服务的能力建设,并带动社区心理学研究的深入。与此同时,由几位澳大利亚教授合作撰写的著作《全科医学之心理健康》已经由中国全科医学杂志社与国内外专家合作进行翻译,并在中国出版发行。希望通过本学术专栏和翻译名著等工作,让中国的全科医学在心理健康服务方面迈上新的台阶。在此衷心感谢担任本栏目翻译点评工作的我刊编委、澳大利亚Monash大学杨辉教授对中国全科医学发展给予的帮助和支持! | Sasha Fehily Grant Blashki Fiona Judd Leon Piterman Hui Yang Shane Thomas | 2014 | 中国全科医学2014,17,7: | 3 |
| 5 | miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway显示文摘Chronic hypoxia is a common inducer of end-stage cardiovascular disease.In cells under hypoxia,the hypoxia-inducible factor-1(HIF-1)plays a vital role in regulating downstream target genes.However,the mechanism of hypoxia in card io myocytes is still unclear.In this study,we aimed to identify novel downstream epigenetic targets of HIF-1α in cardiomyocytes under hypoxia.H9c2 cells were exposed to hypoxia condition,and quantitative real-time PCR analysis was performed to evaluate the expression of miR-20b-5p.The results indicated that the expression of miR-20b-5p was down-regulated in H9c2 cells under low oxygen condition.Meanwhile,HIF-1α overexpression further down-regulated the miR-20b-5p expression in H9c2 cells transfected with HIF-1α plasmids.In addition,Annexin-V-FITC/PI flow cytometry analysis suggested that overexpression of miR-20b-5p attenuated cell apoptosis under hypoxia condition in H9c2 cells.Western blot analysis showed that the hypoxia apparently increased Bax and cleaved-caspase-3,but decreased Bcl-2 expression in H9c2 cells,indicating that hypoxia-induced NF-κB signaling pathway activation is mediated by miR-20b-5p.Hypoxia-induced H9c2 cell apoptosis was reduced after HIF-1α knockdown as shown by the flow cytometry analysis.In conclusion,we identified that miR-20b-5p plays an important role in mediating cardiomyocytes apoptosis under hypoxia,which is mediated by the HIF-1/NF-κB signaling pathway. | Zhongquan Zhou Songwen Chen Zhiming Tian Shibing Deng Xuying Yi Shaning Yang Xuexin Yang Lijun Jin Wanqing Shi | 2020 | Acta Biochimica et Biophysica Sinica2020,52,9: | 2 |
| 6 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020,7,1: | 2 |
| 7 | Do Financial Analysts' Long-term Growth Forecasts Matter? Evidence from Stock Recommendations and Career Outcomes 显示文摘 | Jung B Shane PB Sunny Yang Y | 2012 | Journal of Accounting and Economics2012,,53: | 1 |
| 8 | 病理性博彩的神经生物机制研究显示文摘病理性博彩是博彩领域中的一种不健康博彩行为,该行为是目前博彩研究领域中所关注的焦点问题之一,尤其是其在DSM5中被归为'行为性成瘾'一类后,业界对该主题的研究更加深入具体。应用文献资料法,对国内外有关病理性博彩的概念、评价标准及其演变过程进行全面的梳理,并从认知神经学、神经生物学角度对病理性博彩的神经生物机制进行综述和评述。研究主要发现:病理性博彩者对脑内负责奖赏系统不敏感;博彩线索加工是诱发博彩行为的一个关键因素;病理性博彩者冲动控制神经通路异于正常群体;病理性博彩者大脑某些功能存在障碍是导致其决策障碍的神经机制之一。文章提出了该课题的未来研究方向。 | 白彩梅 王树明 Shane Thomas Hui Yang 马文飞 | 2016 | 首都体育学院学报2016,28,6: | 1 |
| 9 | Porous shape persistent fluorescent polymer films: An approach to TNT sensory materials 显示文摘 | Yang Jye Shane Swager Timothy M | 1998 | J Am Chem Soc1998,120,21: | 1 |
| 10 | Fluorescent porous polymer films as TNT chemosensors: Electronic and structural effects显示文摘 | Yang Jye Shane Swager Timothy M | 1998 | J AmChem Soc1998,120,11: | 1 |
| 11 | 全科医学中的心理健康病案研究(二十三)——病理性赌博障碍显示文摘<正>案例简介:所谓赌博,是指在不能确定结果的场合中,采用金钱或有价值的其他物品作为赌注,其主要目的是赢得额外的金钱或物品的活动。在国际上,70%~85%的成年人报告说在前12个月内曾参与某种形式的赌博活动[1]。问题赌博是指具有持续地赌博的冲动,不在乎有害的消极后果,也没有停止赌博的愿望。新近发布的《精神疾病诊断与统计手册第5版》 | Shane Thomas Hui Yang Grant Blashki Leon Piterman Fiona Judd | 2013 | 中国全科医学2013,16,31: | 1 |
| 12 | NOD2 Variants and Antibody Response to Microbial Antigens in Crohn’s Disease Patients and Their Unaffected Relatives显示文摘 | Shane M. Devlin Huiying Yang Andrew Ippoliti Kent D. Taylor Carol J. Landers Xiaowen Su Maria T. Abreu Konstantinos A. Papadakis Eric A. Vasiliauskas Gil Y. Melmed Phillip R. Fleshner Ling Mei Jerome I. Rotter Stephan R. Targan | 2007 | Gastroenterology2007,,2: | 1 |
| 13 | 全科医学中的心理健康病案研究(十)——谁来照顾心理疾病病人的照顾者显示文摘几年前的一个星期六早晨,我接到一个心情苦恼的病人打来的电话,他让我马上到他家出诊。他告诉我说,如果我不马上到他家的话,他就马上给警察打电话报案,说家里发生了杀人案。虽然电话里听出来他很苦恼,但听上去他是一个还比较理智的老年人。这样一位老年人扬言要杀人,这的确不同寻常。他说将要发生的杀人案的受害者,很可能就是他那位让人烦透了的94岁的岳母。 | Leon Piterman FionaJudd Grant Blashki Hui Yang Shane Thomas | 2013 | 中国全科医学(医生读者版)2013,16,12: | 1 |
| 14 | Adipose-derived stem cells show hepatic differentiation potential and therapeutic effect in rats with acute liver failure显示文摘Hepatocyte transplantation contributes to the repair of liver damage,but hepatocyte resources are limited,making it difficult for this to become a routine treatment.Previous studies have confirmed that mesenchymal stem cells(MSCs)can be induced to differentiate into hepatocyte-like cells(HLCs)by adding different cytokine combinations in vitro,and they then play some roles of hepatocytes.Our previous studies found that the differentiation ability of stem cells is closely related to the origin of the tissue.To identify the mesenchymal stem cells that are most suitable for hepatic differentiation and the treatment of liver failure,we use a three-phase induction process in which human adipose-derived stem cells(hADSCs)and umbilical cord mesenchymal stem cells(hUCMSCs)are induced to differentiate towards HLCs in vitro,and rats with acute liver failure(ALF)induced by D-gal are cured by MSCs and MSC-derived HLCs(MSCs-HLC),respectively.We find that hADSCs are stronger than hUCMSCs in hepatic differentiation ability,and they have a better curative effect when using hADSCs-HLC or jointly using hADSCs and hADSCs-HLC,which has positive significance for hepatocyte regeneration,recovery of liver function and reduction of systemic inflammatory reaction,finally improving the survival rate of rats with acute liver failure. | Yinpeng Jin Rongfeng Shi Tangkai Qi Qiang Li Cong Chen Shane Gao Fengjuan Gao Danjing Yang Guangxi Sun Jianqing Xu Qingchun Fu Jun Xu Xiaoyan Zhang | 2023 | Acta Biochimica et Biophysica Sinica2023,55,4: | 0 |
| 15 | Positron emission tomography as predictor of rectal cancer response during or following neoadjuvant chemoradiation显示文摘Positron emission tomography (PET) shows great promise as a tool to evaluate the effectiveness of rectal cancer neoadjuvant therapy as it has demonstrated high predictive value in several studies. Creating a standardized method of using PET has the potential to reduce ineffective treatments. However, relevant studies have been heterogenous in approach, making any unified standard difficult to establish. PET related parameters used to assess treatment response include magnitude and change of standard uptake value, total lesion glycolysis, and visual response. Finding the best evaluation interval and parameters to use for interpreting PET results in the neoadjuvant treatment of rectal cancer needs additional study. | Shane Hopkins Marwan Fakih Gary Y Yang | 2010 | World Journal of Gastrointestinal Oncology2010,2,5: | 0 |
| 16 | Positron emission tomography's changing significance in the treatment of esophageal cancer显示文摘Incidence of esophageal cancer has been rising,and Positron Emission Tomography(PET) is one tool that has shown utility and promise as a tool for staging,treatment response,and prognosis.PET delivery has evolved over time and is now frequently registered with a CT scan at the time of acquisition.However,resolution and confounders such as post-treatment radiation changes may limit clinical utility.PET has been shown to be helpful in staging,especially in evaluating for distant metastases.PET acquired after chemoradiation may give important prognostic information that can guide additional treatment decisions.Studies have had substantial variability in recommendations for the timing and manner of using PET for this purpose,and additional study is needed. | Shane Hopkins Gary Yang | 2009 | World Journal of Gastrointestinal Oncology2009,1,1: | 0 |
| 17 | Predictors of Occurrence of Left Atrial Appendage Stunning After Electrical Cardioversion of Atrial Fibrillation to Sinus Rhythm显示文摘 Objective To determine the predictors and risk factors of occurrence of atrial appendage stunning after electrical cardioversion of non-valvular atrial fibrillation.…… | Yang Shaning Huang Congxin Hu Xiaojun Jin Lijun Li Fengzhu Peng Shuixian | 2004 | 中国心脏起搏与心电生理杂志2004,18,z1: | 0 |
| 18 | Motivational interviewing and its application in the management of coronary heart disease显示文摘Objective:This review paper explores the concept,spirit,principles,and core skills of moti-vational interviewing(MI)as a psychological approach applied to CHD patients.Methods:Literature reviews based on English and Chinese articles.Results:The English and Chinese literature provided strong evidence for the effectiveness of MI in terms of behavior changes,blood pressure control,hyperglycemia and hyperlipidemia control,compliance improvement,and improving quality of life amongst chronic heart failure patients.The Happy Life Club(HLC)is the only randomized controlled trial(RCT)that examined the effects of MI on behavior changes and self-management improvements in Chinese patients with type 2 diabetes mellitus.The HLC pilot revealed positive outcomes,and RCTs will provide further evidence.Conclusion:MI has been expanded in its application to a wider range of lifestyle-related chronic diseases,including CHD.At the time of this review,MI represents a new concept and ap-proach in China for improving physical and mental health(body and mind)in patients with CHD.In order to integrate MI into medical practice,the authors suggest improving the medical education curriculum and strengthening vocational training,while conducting further research initiatives to assess the innovation and inform practice management. | Yanping Ren Colette Browning Hui Yang Shane Thomas | 2013 | Family Medicine and Community Health2013,1,3: | 0 |
| 19 | 全科医学中的心理健康病案研究(二十四)--谁来照顾心理疾病病人的照顾者?显示文摘中国全科医学杂志与澳大利亚Monash大学和Melbourne大学的全科医学专家和心理学专家在2012年伊始共同推出“全科医学中的心理健康病案研究”学术专栏,该专栏由澳大利亚的几位专家轮流撰写,以介绍社区常见的心理问题及其解决方法为主要内容,获得了读者的广泛好评。今年我刊将继续该学术专栏的登载,以推动我国社区心理学服务的能力建设,并带动社区心理学研究的深入。与此同时,由几位澳大利亚教授合作撰写的著作《全科医学中的精神病学》正在由中国全科医学杂志社与国内外专家合作进行翻译,期望不久在中国出版。希望通过本学术专栏和翻译名著等工作,让中国的全科医学在心理健康服务方面迈上新的台阶。在此衷心感谢担任本栏目翻译点评工作的我刊编委、澳大利亚Monash大学杨辉教授对中国全科医学发展给予的帮助和支持! | Leon Piterman Fiona Judd Grant Blashki Hui Yang Shane Thomas | 2013 | 中国全科医学2013,16,34: | 0 |
| 20 | The‘physical-mental’treatment of cardiovascular disease co-morbid with mental disorders显示文摘A 47-year-old woman complained of sudden chest tightness,shortness of breath,palpitations and a severe headache.Her highest blood pressure had reached 200/120 mmHg before and was diagnosed as hypertension.One month ago,the results of her cranial CT scan showed multiple lacunar cerebral infarctions.She then complained of insomnia,extreme fatigue,poor appetite,loss of interest in everything and paid more attention to her blood pressure and measured blood pressure over five times per day at home.The patient went to visit a psychologist who drew the conclusion of depression.She took sertraline(50 mg once a day)and followed up with the psychologist in the following 2 weeks.During the last month,she has taken 30-mg nifedipine controlledrelease tablets once a day and the blood pressure was well-controlled.More attention should be paid to the mental status of patients with cardiovascular disease.There are many screening tools to assess depression in cardiovascular disease patients.The‘physical-mental’treatment of cardiovascular disease cannot be conducted at one time and follow-ups are necessary. | Yanping Ren Hui Yang Colette Browning Shane Thomas | 2013 | Family Medicine and Community Health2013,1,4: | 0 |