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| 1 | Integrated Inspection of QoM, QoP, and QoS for AOI Industries in Metaverses显示文摘With the rapid development of information technologies such as digital twin, extended reality, and blockchain,the hype around 'metaverse' is increasing at astronomical speed. However, much attention has been paid to its entertainment and social functions. Considering the openness and interoperability of metaverses, the market of quality inspection promises explosive growth. In this paper, taking advantage of metaverses, we first propose the concept of Automated Quality Inspection(Auto QI), which performs integrated inspection covering the entire manufacturing process, including Quality of Materials, Quality of Manufacturing(Qo M), Quality of Products, Quality of Processes(Qo P), Quality of Systems, and Quality of Services(Qo S). Based on the scenarios engineering theory, we discuss how to perform interactions between metaverses and the physical world for virtual design instruction and physical validation feedback. Then we introduce a bottomup inspection device development workflow with productivity tools offered by metaverses, making development more effective and efficient than ever. As the core of quality inspection,we propose Quality Transformers to complete detection task,while federated learning is integrated to regulate data sharing.In summary, we point out the development directions of quality inspection under metaverse tide. | Yutong Wang Yonglin Tian Jiangong Wang Yansong Cao Shixing Li Bin Tian | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，12： | 5 |
| 2 | Effective feature analysis for color image segmentation显示文摘 | Li Ning Mao Shixing | 2001 | Transaction of Nanjing University of Aeronautics2001，，12： | 1 |
| 3 | Mining intrinsic information of convalescent patients after suffering coronavirus disease 2019 in Wuhan显示文摘OBJECTIVE:To summarize the potential characteristics of convalescent patients with coronavirus disease 2019(COVID-19)in China based on emerging clinical tongue data and guide the treatment and recovery of COVID-19 patients from the perspective of Traditional Chinese Medicine tongue diagnosis.METHODS:In this study,we developed and validated radiomics-based and lab-based methods as a novel approach to provide individualized pretreatment evaluation by analyzing different features to mine the orderliness behind tongue data of convalescent patients.In addition,this study analyzed the tongue features of convalescent patients from clinical tongue qualitative values,including thick and thin,fur,peeling,fat and lean,tooth marks and cracked,and greasy and putrid fur.RESULTS:We included 2164 tongue images in total(34%from day 0,35.4%from day 14 and 30.6%from day 28)from convalescent patients.The significance results are shown as follows.Firstly,as the recovery time prolongs,the L average values of tongue and coat decrease from 60.21 to 57.18 and from 60.06 to 57.03 respectively.Secondly,the decrease of abnormality rate of tongue coat,included greasy tongue fur,putrid fur,teeth-mark,thick-thin fur,are of significant statistical difference(P<0.05).Thirdly,the average value of gray-level cooccurrence matrices increases from 0.173 to 0.194,the average value of entropy increases from 0.606 to 0.665,the average value of inverse difference normalized decrease from 0.981 to 0.979,and the average value of dissimilarity decrease from 0.1576 to 0.1828.The details of other radiomics features are describe in results section.CONCLUSIONS:Our experiment shows that patients in different recovery periods have a relationship with quantitative values of tongue images,including L color space of the tongue and coat radiomics features analysis.This relationship can help clinical doctors master the recovery and health of patients as soon as possible and improve their understanding of the potential mechanisms underlying the dynamic changes and mechanisms underlying COVID-19. | YAN Shixing LüYi LIU Ziqing REN Meng HE Haiyang XIAO Li GUO Feng PENG Miao LI Xiaoxia WANG Yong XU Xi YANG Tao SHAO Zuoyu HUANG Jingjing XIAO Mingzhong | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 1 |
| 4 | Design and validation of a navigation system of multimodal medical images for neurosurgery based on mixed reality显示文摘Purpose: This paper aims to develop a navigation system based on mixed reality, which can displaymultimodal medical images in an immersive environment and help surgeons locate the target areaand surrounding important tissues precisely.Methods: To be displayed properly in mixed reality, medical images are processed in this system.High-quality cerebral vessels and nerve fibers with proper colors are reconstructed and exported tomixed reality environment. Multimodal images and models are registered and fused, extracting theirkey information. The multiple processed images are fused with the real patient in the same coordinatesystem to guide the surgery.Results: The multimodal image system is designed and validated properly. In phantom experiments,the average error of preoperative registration is 1.003 mm and the standard deviation is 0.096 mm.The average proportion of well-registered areas is 94.9%. In patient experiments, the surgeons whoparticipated in the experiments generally indicated that the system had excellent performance andgreat application prospect for neurosurgery.Conclusion: This article proposes a navigation system of multimodal images for neurosurgery basedon mixed reality. Compared with other navigation methods, this system can help surgeons locate thetarget area and surrounding important tissues more precisely and rapidly. | Zeyang Zhou Zhiyong Yang Shan Jiang Tao Zhu Shixing Ma Yuhua Li Jie Zhuo | 2023 | Visual Informatics2023，7，2： | 0 |
| 5 | Efficacy of comprehensive cognitive health management for Shanghai community older adults with mild cognitive impairment显示文摘Background The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment,but easy-to-implement management methods are lacking.Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cognitive function of older adults in the community with normal cognition(NC)and mild cognitive impairment(MCI).Methods The comprehensive cognitive health management programme included a psychiatric assessment of the cognitive risk factors for those in the intervention groups and individualised recommendations for reducing the risks through self-management supported by regular medical professional follow-up.The intervention groups for this study included 84 elderly participants with NC and 43 elderly participants with MCI who received comprehensive cognitive health management.The control groups included 84 elderly participants with NC and 43 elderly participants with MCI who matched the intervention group’s general characteristics and scale scores using the propensity matching score analysis.The Montreal Cognitive Assessment(MoCA)scale and Geriatric Depression Scale(GDS)scores were compared after a 1-year follow-up.Results For older adults with MCI in the intervention group,MoCA scores were higher at the 1-year followup than at baseline(24.07(3.674)vs 22.21(3.052),p=0.002).For the MoCA subscales,the intervention group’s abstract and delayed memory scores had significantly increased during the 1-year follow-up.Furthermore,in a generalised linear mixed model analysis,the interaction effect of group×follow-up was statistically significant for the MCI group(F=6.61,p=0.011;coefficients=5.83).Conclusions After the comprehensive cognitive health management intervention,the older adults with MCI in the community showed improvement at the 1-year follow-up.This preliminary study was the first to demonstrate an easy-to-implement strategy for modifying the cognitive risk factors of elderly individuals with MCI in the community,providing new insight into early-stage intervention for dementia. | Jiayuan Qiu Lu Zhao Shifu Xiao Shaowei Zhang Ling Li Jing Nie Li Bai Shixing Qian Yang Yang Michael Phillips Meiqing Sheng Yuan Fang Xia Li | 2022 | General Psychiatry2022，35，4： | 0 |
| 6 | Effects of Qingkailing on Experimental Allergic Uveitis in Rabbits显示文摘Experimental allergic uveitis(EAU)in rabbits was induced by singleintraocular injection of bovine serum albumin(BSA).The average of protein con-centration in aqueous humor of untreated group of rabbits was 14.33±1.21mg/mland the count of tritiated thymidine(~3H-TdR)incorporated into lymphocyte T was3,987±1,156cpm/10~6.The specific antibody responses to BSA in the serum andthe aqueous were 0.508±0.034 and 0.369±0.019(OD)respectively.Meanwhile,the effect of Qingkailing on EAU was observed in comparison wi... | Shixing Hu Shaozhen Li Chufang Xie Suhua Pan Xiangkun Huang Winifred Mao Zhongshan Ophthalmic Center,Sun Yat-sen University of Medical Sciences Guangzhou 510060,China | 1992 | 眼科学报1992，8，3： | 0 |
| 7 | High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis显示文摘Drug delivery via intra-articular(IA)injection has proved to be effective in osteoarthritis(OA)therapy,limited by the drug efficiency and short retention time of the drug delivery systems(DDSs).Herein,a series of modified cross-linked dextran(Sephadex,S0)was fabricated by respectively grafting with linear alkyl chains,branched alkyl chains or aromatic chain,and acted as DDSs after ibuprofen(Ibu)loading for OA therapy.This DDSs expressed sustained drug release,excellent anti-inflammatory and chondroprotective effects both in IL-1βinduced chondrocytes and OA joints.Specifically,the introduction of a longer hydrophobic chain,particularly an aromatic chain,distinctly improved the hydrophobicity of S0,increased Ibu loading efficiency,and further led to significantly improving OA therapeutic effects.Therefore,hydrophobic microspheres with greatly improved drug loading ratio and prolonged degradation rates show great potential to act as DDSs for OA therapy. | Zhimin Li Xianjing Feng Shixing Luo Yanfeng Ding Zhi Zhang Yifeng Shang Doudou Lei Jinhong Cai Jinmin Zhao Li Zheng Ming Gao | 2023 | Asian Journal of Pharmaceutical Sciences2023，18，4： | 0 |
| 8 | Viral metagenomics analysis of feces from coronary heart disease patients reveals the genetic diversity of the Microviridae显示文摘Recent studies have declared that members of the ss DNA virus family Microviridae play an important role in multiple environments, as they have been found taking a dominant position in the human gut. The aim of this study was to analyze the overall composition of the gut virome in coronary heart disease(CHD) patients, and try to discover the potential link between the human gut virome and CHD. Viral metagenomics methods were performed to detect the viral sequences in fecal samples collected from CHD inpatients and healthy persons as controls. We present the analysis of the virome composition in these CHD patients and controls. Our data shows that the virome composition may be linked to daily living habits and the medical therapy of CHD.Virgaviridae and Microviridae were the two dominant types of viruses found in the enteric virome of CHD patients. Fourteen divergent viruses belonging to the family Microviridae were found, twelve of which were grouped into the subfamily Gokushovirinae, while the remaining two strains might represent two new subfamilies within Microviridae, according to the phylogenetic analysis. In addition, the genomic organization of these viruses has been characterized. | Lianghua Guo Xiuguo Hua Wen Zhang Shixing Yang Quan Shen Haibing Hu Jingjiao Li Zhijian Liu Xiaochun Wang Hua Wang Chenglin Zhou Li Cui | 2017 | Virologica Sinica2017，32，2： | 0 |
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