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| 1 | nvolvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis显示文摘 | Haiyan Chu Ting Wu Wenyu Wu Wenzhen Tu Shuai Jiang Sidi Chen Yanyun Ma Qingmei Liu Xiaodong Zhoua Li Jin Jiucun Wang | 2015 | Protein & Cell2015,6,8: | 5 |
| 2 | Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens显示文摘Dear Editor,The global monkeypox(Mpox)outbreak leads to a surge in demand for vaccine.The Mpox vaccine in short supply is JYNNEOS(modified vaccinia ankara,MVA)due to less side effects,while ACAM2000 supply is abundant because of the strategic stockpile in U.s.1 The ACAM2000 replaced the first-generation smallpox vaccine Dryvax that has a questionable safety profile.However,the ACAM2000 is associated with high rate of myocarditis and pericarditis,and can cause severe illness in immunocompromised patients,foreshadowing the need to update the strategic stockpile. | Zhenhao Fang Valter S.Monteiro Paul A.Renauer Xingbo Shang Kazushi Suzuki Xinyu Ling Meizhu Bai Yan Xiang Andre Levchenko Carmen J.Booth Carolina Lucas Sidi Chen | 2023 | Cell Research2023,33,5: | 1 |
| 3 | A cyanatecstcr/microcapsule system with low cure temperature and self-healing capacity显示文摘 | Li Yuan Sidi Huang Aijuan Gu Guozheng Liang Feng Chen Yinghui Hu Steven Nutt | 2013 | Composites Sci- ence and Technology2013,87,: | 1 |
| 4 | Functionalization of PEG-PM PC-based polymers for potential theranostic applications显示文摘The synergistic effect of polyethylene glycol(PEG)and poly(2-methacry-loyloxyethyl phosphorytcholine)(PMPC)can effectively reduce the protein absorption,which is beneficial to theranostics.However,PEG-PMPC-based polymers have rarely been used as nanocarriers in the theranostic field due to their limited modifiability and weak interaction with other materials.Herein,a plain method was proposed to endow them with the probable ability of loading small active agents,and the relationship between the structure and the ability of loading hydrophobic agents was explored,thus expanding their applications.Firstly,mPEG-PMPC or 4-arm-PEG-PMPC polymer was synthesized by atom transfer radical polymerization(ATRP)using mPEG-Br or 4-arm-PEG-Br as the macroinitiator.Then a strong hydrophobic segment,poly(butyl methacrylate)(PBMA),was introduced and the ability to load small hydrophobic agents was further explored.The results showed that linear mPEG-PMPC-PBMA could form micelles 50-80 nm in size and load the hydrophobic agent such as Nile red efficiently.In contrast,star-like 4-arm-PEG-PMPC-PBiyiA,a monomolecular micelle(10-20 nm),could hardly load any hydrophobic agent.This work highlights effective strategies for engineering PEG-PMPC-based polymers and may facilitate the further application in numerous fields. | Ning CHEN Sidi LI Xueping LI Lixia LONG Xubo YUAN Xin HOU Jin ZHAO | 2021 | Frontiers of Materials Science2021,15,2: | 0 |
| 5 | Preclinical characterization and anti-SARS-CoV-2 efficacy of ATV014:an oral cyclohexanecarboxylate prodrug of 1′-CN-4-aza-7,9-dideazaadenosine C-nucleoside显示文摘Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the causative agent of the global pandemic coronavirus disease 2019(COVID-19),has proven itself to be a highly virulent respiratory pathogen with an unpredictable evolutionary capacity,posing a persistent threat to mankind.At the time of this manuscript’s publication. | Qifan Zhou Sidi Yang Liu Cao Yang Yang Tiefeng Xu Qishu Chen Hongzhou Lu Yingjun Li Deyin Guo Xumu Zhang | 2023 | Signal Transduction and Targeted Therapy2023,8,2: | 0 |
| 6 | Lateral organic-inorganic hybrid Vis-NIR photodetectors based on GaN nanowires promoting photogenerated carriers transfer显示文摘The narrow bandgap of the low-energy near-infrared(NIR)polymer would lead to overlap between adjacent energy levels,which is a major barrier to the preparation of Vis-NIR polymer bulk hetero-junction(BHJ)photodetectors with small responsivity and photocurrent.In this study,a high-performance lateral inorganic-organic hybrid photodetector was constructed to eliminate this barrier by combining GaN nanowires(GaN-NWs)with PDPP3T:PC61BM-based BHJ.In stage one,high-quality GaN-NWs were synthesized by the catalyst-free CVD method.The mechanism for controlling GaN-NWs morphology by adjusting the NH3 flow rate was revealed.In stage two,the GaN-NWs with large electron mobility were used to accelerate the transfer of photogenerated carriers in the BHJ layer.Finally,compared with the BHJ device,the BHJ/GaN device demonstrated obvious improvements in responsivity and photocurrent at the wavelength between 400 and 1000 nm.The responsivity and photocurrent increased over 20-fold at the NIR band of 800e900 nm.Besides,owing to the energy level gradient effect,the BHJ/GaN device has a response speed of 7.8/<5.0 ms,which increases over three orders of magnitude than that of the GaN-NWs-based device(tr/tf:7.1/10.9 s).Therefore,the novel device structure proposed in this work holds great potential for preparing high-performance Vis-NIR photodetectors. | Tao Han Zexin Wu Zhilong Deng Xiaofeng Zhang Sidi Yang Cuicui Chen Jiajia Zhu Shufang Ding Chunzhi Jiang | 2022 | Journal of Materiomics2022,8,4: | 0 |
| 7 | Erratum to:Functionalization of PEG–PMPC-based polymers for potential theranostic applications显示文摘In the original version of this article, the first affiliation “Tianjin Key Laboratory of Composite and Functional Materials,Tianjin 300350, China” should be “Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University,Tianjin 300350, China”. | Ning CHEN Sidi LI Xueping LI Lixia LONG Xubo YUAN Xin HOU Jin ZHAO | 2021 | Frontiers of Materials Science2021,15,4: | 0 |
| 8 | Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages显示文摘Dear Editor,SARS-CoV-2 rapidly evolves during the pandemic1 with many variants of concern(VoCs)lineages(Supplementary Fig.S1a).Omicron(B.1.1.529)and its sub-lineages led to multiple infection waves globally.2 Omicron subvariants harbored a high number of mutations,especially in the spike(S)glycoprotein,and clustered in the receptor-binding domain(RBD)(Supplementary Fig.S1b,c;Supplemental Discussion).These subvariants drastically decrease the efficacy of current vaccinations and monoclonal antibody therapies. | Ping Ren Yingxia Hu Lei Peng Luojia Yang Kazushi Suzuki Zhenhao Fang Meizhu Bai Liqun Zhou Yanzhi Feng Yongji Zou Yong Xiong Sidi Chen | 2023 | Signal Transduction and Targeted Therapy2023,8,8: | 0 |