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| 1 | The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types显示文摘The Genome Sequence Archive(GSA)is a data repository for archiving raw sequence data,which provides data storage and sharing services for worldwide scientific communities.Considering explosive data growth with diverse data types,here we present the GSA family by expanding into a set of resources for raw data archive with different purposes,namely,GSA(https://ngdc.cncb.ac.cn/gsa/),GSA for Human(GSA-Human,https://ngdc.cncb.ac.cn/gsa-human/),and Open Archive for Miscellaneous Data(OMIX,https://ngdc.cncb.ac.cn/omix/).Compared with the 2017 version,GSA has been significantly updated in data model,online functionalities,and web interfaces.GSA-Human,as a new partner of GSA,is a data repository specialized in human genetics-related data with controlled access and security.OMIX,as a critical complement to the two resources mentioned above,is an open archive for miscellaneous data.Together,all these resources form a family of resources dedicated to archiving explosive data with diverse types,accepting data submissions from all over the world,and providing free open access to all publicly available data in support of worldwide research activities. | Tingting Chen Xu Chen Sisi Zhang Junwei Zhu Bixia Tang Anke Wang Lili Dong Zhewen Zhang Caixia Yu Yanling Sun Lianjiang Chi Huanxin Chen Shuang Zhai Yubin Sun Li Lan Xin Zhang Jingfa Xiao Yiming Bao Yanqing Wang Zhang Zhang Wenming Zhao | 2021 | Genomics, Proteomics & Bioinformatics2021，19，4： | 38 |
| 2 | GSA:Genome Sequence Archive显示文摘With the rapid development of sequencing technologies towards higher throughput and lower cost, sequence data are generated at an unprecedentedly explosive rate. To provide an efficient and easy-to-use platform for managing huge sequence data, here we present Genome Sequence Archive(GSA; http://bigd.big.ac.cn/gsa or http://gsa.big.ac.cn), a data repository for archiving raw sequence data. In compliance with data standards and structures of the International Nucleotide Sequence Database Collaboration(INSDC), GSA adopts four data objects(Bio Project, Bio Sample,Experiment, and Run) for data organization, accepts raw sequence reads produced by a variety of sequencing platforms, stores both sequence reads and metadata submitted from all over the world,and makes all these data publicly available to worldwide scientific communities. In the era of big data, GSA is not only an important complement to existing INSDC members by alleviating the increasing burdens of handling sequence data deluge, but also takes the significant responsibility for global big data archive and provides free unrestricted access to all publicly available data in support of research activities throughout the world. | Yanqing Wang Fuhai Song Junwei Zhu Sisi Zhang Yadong Yang Tingting Chen Bixia Tang Lili Dong Nan Ding Qian Zhang Zhouxian Bai Xunong Dong Huanxin Chen Mingyuan Sun Shuang Zhai Yubin Sun Lei Yu Li Lan Jingfa Xiao Xiangdong Fang Hongxing Lei Zhang Zhang Wenming Zhao | 2017 | Genomics, Proteomics & Bioinformatics2017，15，1： | 13 |
| 3 | Common blackbirds Turdus merula use anthropogenic structures as nesting sites in an urbanized landscape显示文摘 | YanDingWANG Qin HUANG Sisi LAN Qin ZHANG Shuihua CHEN | 2015 | Current Zoology2015，61，3： | 3 |
| 4 | Establishing Standardized Biomedical Laboratory Technician Education for the Development of Biotech no logy Research in China显示文摘Chinese scientists have been actively engaged in biotechnology research since the mid-2Oth century.However,biotechnology education,especially biomedical laboratory technology education,is relatively scarce in China.More and more cutting-edge equipment and techniques have been introduced into biomedical laboratories in China,but there is a lack of high-quality techni&ans to apply these advancements to scientific research.In addition,the traditional education and apprenticeship systems have been demonstrated little progress.To address this gap,West China Hospital of Sichuan University established a 2-year educational program for laboratory technology in 2006 based on the residency training program.The project integrates scientific methods into the research laboratory technician training in relevant disciplines,and has developed a systematic,scientific,and effective standardized training system to cultivate high-level and stable experimental technician team for the need of advanced laboratories,which has been demonstrated gready improve the efficiency of biomedical researchers and laboratory facilities.In this article,we introduce the practical experience in establishment and development of a standardized training system for biomedical laboratory technicians to ensure the sustainable development of medical researches. | Guonian Zhu Qiang Huang Yu Ding Jinkui Pi Lan Zhan Sisi Wu | 2020 | Chinese Medical Sciences Journal2020，35，2： | 1 |
| 5 | Variation in reproductive life-history traits of Chinese Bulbuls(Pycnonotus sinensis)along the urbanization gradient in Hangzhou,China显示文摘Urbanization brings new selection pressures to wildlife living in cities,and changes in the life-history traits of urban species can reflect their responses to such pressures.To date,most of the studies investigating the impacts of urbanization on avian life-history traits are conducted in Europe and North America,while such studies are often lacking in quickly developing countries in Asia(e.g.,China).In this study,we examined the variations in reproductive life-history traits of Chinese Bulbuls(Pycnonotus sinensis)along the urbanization gradient in Hangzhou,China.We detected 234 natural nests of Chinese Bulbuls and continuously monitored them in two continuous breeding seasons from 2012 to 2013.We collected data on seven life-history traits(laying date,incubation period,nestling period,clutch size,egg volume,hatching success rate,and fledging success rate).We used infrared cameras to record the number of feedings per hour as the measure of food resources for the nestlings.We measured nest predation pressure by monitoring 148 natural breeding nests during breeding seasons and 54 artificial nests immediately after breeding seasons.We then calculated the urbanization synthetic index(USI)as a measure of the level of urbanization and examined its relationship with the seven life-history traits.We found that Chinese Bulbuls laid eggs significantly earlier with increasing USI.However,the other six life-history traits did not vary significantly with the USI.Moreover,the feeding frequency of chicks increased significantly with the USI,but the nest predation pressure of Chinese Bulbuls decreased significantly with the USI.Increased food resources and reduced nest predation pressure in cities may lead to earlier laying date of Chinese Bulbuls.Further study should test whether the earlier laying date of Chinese Bulbuls is the result of phenotypic plasticity or genetic change. | Xingmin Chen Qin Zhang Sisi Lan Qin Huang Shuihua Chen Yanping Wang | 2023 | Avian Research2023，14，2： | 0 |
| 6 | Efficient quantum dot infrared solar cells with enhanced lowenergy photon conversion via optical engineering显示文摘Infrared(IR)solar cells are promising devices for improving the power conversion efficiency(PCE)of conventional solar cells by expanding the utilization region of the sunlight spectrum to near-infrared range.IR solar cells based on colloidal quantum dots(QDs)have attracted extensive attention due to the widely tunable absorption spectrum controlled by dot size and the unique solution processibility.However,the trade-off in QD solar cells between light absorption and photo-generated carrier collection has limited the further improvement of PCE.Here,we present high-performance PbS QD IR solar cells resulting from the combination of boosted light absorption and optimized carrier extraction.By constructing an optical resonance cavity,the light absorption is significantly enhanced in the range of 1,150–1,300 nm at a relatively thin photoactive layer.Meanwhile,the thin photoactive layer facilitates efficient carrier extraction.Consequently,the PbS QD IR solar cells exhibit a highly efficient photoelectric conversion in the IR region,resulting in a high IR PCE of 1.3%which is comparable to the highest value of solution-processed IR solar cells based on PbSe QDs.These results demonstrate that constructing an optical resonance cavity is a reasonable strategy for effective conversion of photons in the devices aiming at light in a relatively narrow wavelength range,such as IR solar cells and narrow band photodetectors. | Sisi Liu Ming-Yu Li Kao Xiong Jianbo Gao Xinzheng Lan Daoli Zhang Liang Gao Jianbing Zhang Jiang Tang | 2023 | Nano Research2023，16，2： | 0 |
| 7 | Nest predation pressure on Chinese Bulbuls decreases along the urbanization gradient in Hangzhou,China显示文摘Nest predation is an essential factor affecting bird population density,reproductive ecology and life cycle.However,there are still contradictory results about how nest predation pressure changes with urbanization.One of the reasons for the controversy is that previous studies often use artificial nests to investigate nest predation,but the result of artificial nests is often biased and contrary to that of natural nests.Therefore,it is important to perform nest predation experiments simultaneously with both natural and artificial nests.In this study,we examined the change of nest predation pressure on the Chinese Bulbul(Pycnonotus sinensis)along the urbanization gradient in Hangzhou,China.We detected 148 natural nests of Chinese Bulbuls and continuously monitored them in two continuous breeding seasons from 2012 to 2013.After the breeding season,we placed artificial eggs in natural nests of Chinese Bulbuls to investigate the changes in nest predation pressure and used infrared cameras to record the predators.We then calculated the urbanization synthetic index(USI)as the measure of the degree of urbanization and examined its relationship with nest predation pressure.We found that no matter whether natural nests or artificial eggs were used,the nest predation pressure always decreased significantly with the degree of urbanization.The average height of shrubs within 10 m of the nest differed significantly between the predated and unpredated nests,which also affected the risk of nest predation.Our study highlights the importance of using natural and artificial nests simultaneously to conduct nest predation experiments,which can reduce the bias or errors caused by only using artificial nests.We also recommend the use of infrared cameras in future nest predation studies,which has obvious advantages in monitoring and identifying potential predators. | Xingmin Chen Qin Zhang Sisi Lan Shuihua Chen Yanping Wang | 2022 | Avian Research2022，13，3： | 0 |
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