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| 1 | Load Balancing-Based Routing Optimization Mechanism for Power Communication Networks显示文摘In power communication networks, it is a challenge to decrease the risk of different services efficiently to improve operation reliability. One of the important factor in reflecting communication risk is service route distribution. However, existing routing algorithms do not take into account the degree of importance of services, thereby leading to load unbalancing and increasing the risks of services and networks. A routing optimization mechanism based on load balancing for power communication networks is proposed to address the abovementioned problems. First, the mechanism constructs an evaluation model to evaluate the service and network risk degree using combination of devices, service load, and service characteristics. Second, service weights are determined with modified relative entropy TOPSIS method, and a balanced service routing determination algorithm is proposed. Results of simulations on practical network topology show that the mechanism can optimize the network risk degree and load balancing degree efficiently. | Ningzhe Xing Siya Xu Sidong Zhang Shaoyong Guo | 2016 | China Communications2016，13，8： | 10 |
| 2 | A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China显示文摘The coronavirus disease 2019(COVID-19)pandemic is a global crisis,and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses.This study aimed to assess COVID-19-related essential clinical resource demands in China,based on different scenarios involving COVID-19 spreads and interventions.We used a susceptible–exposed–infectious–hospitalized/isolated–removed(SEIHR)transmission dynamics model to estimate the number of COVID-19 infections and hospitalizations with corresponding essential healthcare resources needed.We found that,under strict non-pharmaceutical interventions(NPIs)or mass vaccination of the population,China would be able to contain community transmission and local outbreaks rapidly.However,under scenarios involving a low intensity of implemented NPIs and a small proportion of the population vaccinated,the use of a peacetime–wartime transition model would be needed for medical source stockpiles and preparations to ensure a normal functioning healthcare system.The implementation of COVID-19 vaccines and NPIs in different periods can influence the transmission of COVID-19 and subsequently affect the demand for clinical diagnosis and treatment.An increased proportion of asymptomatic infections in simulations will not reduce the demand for medical resources;however,attention must be paid to the increasing difficulty in containing COVID-19 transmission due to asymptomatic cases.This study provides evidence for emergency preparations and the adjustment of prevention and control strategies during the COVID-19 pandemic.It also provides guidance for essential healthcare investment and resource allocation. | Ting Zhang Qing Wang Zhiwei Leng Yuan Yang Jin Yang Fangyuan Chen Mengmeng Jia Xingxing Zhang Weiran Qi Yunshao Xu Siya Chen Peixi Dai Libing Ma Luzhao Feng Weizhong Yang | 2021 | Engineering2021，7，7： | 7 |
| 3 | Computed tomography and magnetic resonance imaging evaluation of pelvic lymph node metastasis in bladder cancer显示文摘Background:Accurate evaluation of lymph node metastasis in bladder cancer(BCa)is important for disease staging,treatment selection,and prognosis prediction.In this study,we aimed to evaluate the diagnostic accuracy of com-puted tomography(CT)and magnetic resonance imaging(MRI)for metastatic lymph nodes in BCa and establish criteria of imaging diagnosis.Methods:We retrospectively assessed the imaging characteristics of 191 BCa patients who underwent radical cys-tectomy.The data regarding size,shape,density,and diffusion of the lymph nodes on CT and/or MRI were obtained and analyzed using Kruskal-Wallis test and χ^(2) test.The optimal cutoff value for the size of metastatic node was deter-mined using the receiver operating characteristic(ROC)curve analysis.Results:A total of 184 out of 3317 resected lymph nodes were diagnosed as metastatic lymph nodes.Among 82 imaging-detectable lymph nodes,51 were confirmed to be positive for metastasis.The detection rate of metastatic nodes increased along with more advanced tumor stage(P<0.001).Once the ratio of short-to long-axis diameter≤0.4 or fatty hilum was observed in lymph nodes on imaging,it indicated non-metastases.Besides,lymph nodes with spiculate or obscure margin or necrosis indicated metastases.Furthermore,the short diameter of 6.8 mm was the optimal threshold to diagnose metastatic lymph node,with the area under ROC curve of 0.815.Conclusions:The probability of metastatic nodes significantly increased with more advanced T stages.Once lymph nodes are detected on imaging,the characteristic signs should be paid attention to.The short diameter>6.8 mm may indicate metastatic lymph nodes in BCa. | Yong Li Feiyu Diao Siya Shi Kaiwen Li Wangshu Zhu Shaoxu Wu Tianxin Lin | 2018 | Cancer Communications2018，38，1： | 7 |
| 4 | miR-125b-5p and miR-99a-5p downregulate human γδ T-cell activation and cytotoxicity显示文摘As an important component of innate immunity,human circulatingγδT cells function in rapid responses to infections and tumorigenesis.MicroRNAs(miRNAs)play a critical regulatory role in multiple biological processes and diseases.Therefore,how the functions of circulating humanγδT cells are regulated by miRNAs merits investigation.In this study,we profiled the miRNA expression patterns in human peripheralγδT cells from 21 healthy donors and identified 14 miRNAs that were differentially expressed between peripheralαβT cells andγδT cells.Of the 14 identified genes,7 miRNAs were downregulated,including miR-150-5p,miR-450a-5p,miR-193b-3p,miR-365a-3p,miR-31-5p,miR-125b-5p and miR-99a-5p,whereas the other 7 miRNAs were upregulated,including miR-34a-5p,miR-16-5p,miR-15b-5p,miR-24-3p,miR-22-3p,miR-22-5p and miR-9-5p,inγδT cells compared withαβT cells.In subsequent functional studies,we found that both miR-125b-5p and miR-99a-5p downregulatedγδT cell activation and cytotoxicity to tumor cells.Overexpression of miR-125b-5p or miR-99a-5p inγδT cells inhibitedγδT cell activation and promotedγδT cell apoptosis.Additionally,miR-125b-5p knockdown facilitated the cytotoxicity ofγδT cells toward tumor cells in vitro by increasing degranulation and secretion of IFN-γand TNF-α.Our findings improve the understanding of the regulatory functions of miRNAs inγδT cell activation and cytotoxicity,which has implications for interventional approaches toγδT cell-mediated cancer therapy. | Yuli Zhu Siya Zhang Zinan Li Huaishan Wang Zhen Li Yu Hu Hui Chen Xuan Zhang Lianxian Cui Jianmin Zhang Wei He | 2019 | Cellular & Molecular Immunology2019，16，2： | 5 |
| 5 | Blockchain-Based Reliable Fog-Cloud Service Solution for IIoT显示文摘Industrial Internet of things(IIoT)deploys a large number of smart devices to obtain industrial data,which will be transmitted to cloud for analysis to improve industrial productivity.The management of large-scale devices is complicated,and it’s also a challenge to choose a high-quality cloud service for data analysis as the number of service with similar functions increases.To address these issues,we propose a reliable fog-cloud service solution with blockchain-based fog-cloud architecture.In fog layer,we build a management blockchain between fog servers and design a management method for industrial devices;In cloud layer,we construct a service blockchain between cloud service providers to form an open'service market'.Quality of service and reputation based matching algorithm and reputation-based consensus algorithm are designed.The simulation results show correctness and efficiency of algorithms,and validate effectiveness of our proposed solution. | DAI Meiling XU Siya SHAO Sujie GUO Shaoyong QIU Xuesong XIONG Ao | 2021 | Chinese Journal of Electronics2021，30，2： | 3 |
| 6 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 7 | Design of large-displacement asymmetric piezoelectric microgripper based on flexible mechanisms显示文摘The output displacement of the traditional symmetrical microgripper is large,but its micro-components or parts are easily damaged due to the uneven force exerted on the left and right jaws of the gripper.The output force of the traditional asymmetric microgripper is stable.However,its output displacement is small,typically half the output displacement of the symmetric microgripper.To solve these problems,in this study,we designed a large-displacement asymmetric microgripper.First,we calculated the relationship between the theoretical input and output variables based on their geometric relationship.Then,we analyzed the performance of the microgripper using finite element software.Lastly,we used a piezoelectric actuator as the input driver of the microgripper.The errors associated with the theoretical and simulated output displacements were 7.05%and 9.24%,respectively.At 150 V of driving voltage,the maximum output displacement was 224μm,and the actual magnificationwas 11.2 times.Microparts can be gripped in parallel and stably,which confirms the validity of the design. | Xiaodong Chen Siya Hu Zilong Deng Jinhai Gao Xingjun Gao | 2019 | Nanotechnology and Precision Engineering2019，2，4： | 2 |
| 8 | Load-Balancing and QoS Based Dynamic Resource Allocation Method for Smart Gird Fiber-Wireless Networks显示文摘Real-time network resource allocation based on virtualization technology is an important method to solve the solidification problem of Fiber-wireless(Fi-Wi)access networks.To increase the resource utilization and meet the specific QoS requirements of smart gird communication services,a Load-balancing and QoS based dynamic resource allocation method(LbQ-DR)is proposed with three sub-mechanisms.A time-window based substrate network resource update mechanism is designed to describe the realtime resource consumption of substrate networks,which can balance the accuracy of resource status and the complexity of the allocation algorithm.A QoS-based Virtual network request(VNR)sorting mechanism is presented to precisely calculate the priority of VNRs and reasonably sort the incoming services.A load-balancing based resource allocation mechanism is designed to avoid unbalanced resource consumption.Especially,the channel interference is considered in the cost of embedding and a collision domain mechanism is introduced to decrease interference.Simulation results demonstrate that the proposed method can provide heterogeneous smart grid businesses with differentiated service,improve the utilization and economic benefits of the network and make the network more balanced. | XU Siya LI Peng QI Feng GUO Shaoyong ZHOU Guiping DENG Wei LI Yueyue | 2019 | Chinese Journal of Electronics2019，28，6： | 1 |
| 9 | Sequence analysis and typing of Saprolegnia strains isolated from freshwater fish from Southern Chinese regions显示文摘Saprolegniasis,caused by Saprolegnia infection,is one of the most common diseases in freshwater fish.Our study aimed to determine the epidemiological characteristics of saprolegniasis in Chinese regions of high incidence.Saprolegnia were isolated and identified by morphological and molecular methods targeting the internal transcribed spacer(ITS)ribosomal DNA(rDNA)and building neighbor-joining(NJ)and maximum parsimony(MP)phylogenetic trees.The ITS sequences of eight isolated strains were compared with GenBank sequences and all strains fell into three clades:CLADE1(02,LP,04 and 14),CLADE2(S1),and CLADE3(CP,S2,L5 and the reference ATCC200013).Isolates 02 and LP shared 80%sequence similarity with S.diclina,S.longicaulis,S.ferax,S.mixta,and S.anomalies.Further,isolates 04 and 14 shared 80%similarity with S.bulbosa and S.oliviae.Finally,extremely high ITS sequence similarities were identified between isolates S1 and S.australis(100%);CP and S.hypogyna(96%);and S2,L5,ATCC200013 and S.salmonis(98%).This research provides insights into the identification,prevention and control of saprolegniasis pathogens and the potential development of effective drugs. | Siya Liu Pengpeng Song Renjian Ou Wenhong Fang Mao Lin Jiming Ruan Xianle Yang Kun Hu | 2017 | Aquaculture and Fisheries2017，2，5： | 1 |
| 10 | Shrimp Waste Fermentation Using Symbiotic Lactic Acid Bacteria显示文摘 | SHAN DUAN LI LEI LIU SIYA | 2011 | Advanced Materials Research2011，，： | 1 |
| 11 | Improved production of chitin from shrimp waste by fermentation with epiphytic lactic acid bacteria显示文摘 | SHAN DUAN LI LEI LIU SIYA | 2012 | Carbohydrate Polymers2012，，89： | 1 |
| 12 | Design of a flexible piezoelectric microgripper based on combined amplification principles显示文摘Aiming to address the problem of the low amplification ratio of traditional microgrippers,a two-stage microgripper based on the principle of combined amplification was designed with a high amplification ratio and large displacement,using a simple and compact structure.The relationship between theoretical input variables and output variables were first calculated by a projection theorem.Secondly,the performance of the microgripper was analyzed by finite element analysis(FEA).Finally,the accuracy of the theoretical calculation and FEA was verified experimentally.The results show that the microgripper has high magnification and can be gripped in parallel,with self-adaptability for many irregular shaped micro objects.The actual magnification was 23.2×,which is greater than similar products. | Xiaodong Chen Zilong Deng Siya Hu Jinhai Gao Xingjun Gao | 2019 | Nanotechnology and Precision Engineering2019，2，3： | 1 |
| 13 | Studies on anodic oxide coating with low absorbance and high emittance on aluminum alloy 2024显示文摘 | Siya Kumar C Sharma A K Mahendra K N | 2000 | Solar Energy Materials and Solar Cells2000，60，1： | 1 |
| 14 | Relationship between the Structure and Hydrophobic Perform- ance of Ni- TiO2 Nanocomposite Coatings by Electrodeposition显示文摘 | Huang Siya Hu Yawei Pan Wei | 2011 | Surface & Coatings Tech- nology2011，205，： | 1 |
| 15 | Lymphatic endothelial cells regulate B-cell homing to lymph nodes via a NIK-dependent mechanism显示文摘B cells home to the lymph nodes(LNs)via high endothelial venules(HEVs)under the guidance of chemokines,particularly CXCL13.However,as CXCL13 is not directly made in HEVs,the molecular mechanism mediating B-cell homing to LNs has remained unclear.We show here that nuclear factor(NF)-κB-inducing kinase(NIK),a kinase mediating activation of the noncanonical NF-κB pathway,functions in lymphatic endothelial cells(LECs)to regulate B-cell homing to LNs.LEC-conditional deletion of NIK in mice did not affect the integrity or global function of lymphatic vessels but caused a severe reduction in the frequency of B cells in LNs.The LEC-specific NIK deficiency did not affect the survival of B cells or the frequency of B cells in the spleen.B-cell adoptive transfer studies revealed that the LEC-specific NIK deletion impairs the ability of LNs to recruit B cells.We further show that NIK mediates expression of the chemokines CXCL13 and CCL19 in LECs.Although CCL19 is also expressed in blood endothelial cells(BECs),CXCL13 is not produced in BECs.These results suggest that NIK regulates naive B-cell homing to LNs via mediating production of the B-cell homing chemokine CXCL13 in LECs. | Jie Yang Siya Zhang Lingyun Zhang Xiaoping Xie Hui Wang Zuliang Jie Meidi Gu Jin-Young Yang Xuhong Cheng Shao-Cong Sun | 2019 | Cellular & Molecular Immunology2019，16，2： | 1 |
| 16 | An improved synthesis of methyl carbamates显示文摘 | Siya R W Dean S T Leroy B | 1985 | Org Prep Proced Int1985，17，3： | 1 |
| 17 | Human activity and climate change triggered the expansion of rocky desertification in the karst areas of Southwestern China显示文摘It is conducive to the sustainable development of human beings in karst regions to research the mechanism of karst rocky desertification(KRD)expansion.Whether the large-scale KRD in southwestern China is caused by climate change or human activities is still controversial.In this study,the evolution of the KRD in southwestern China over the past 2000 years was reconstructed through the high-precisionδ^(13)C record of stalagmites from Shijiangjun(SJJ)Cave,Guizhou Province,China.Theδ^(13)C of the stalagmites from SJJ Cave exhibited heavy values from the Medieval Warm Period(MWP)to the Little Ice Age(LIA).Furthermore,theδ^(13)C records of other stalagmites and tufa from southwestern China also showed the same significant heavy trend.Because the stalagmiteδ^(13)C could record the change of ecological environment,it indicated that the consistent change of the stalagmitesδ^(13)C may record the process of KRD expansion in the karst regions of southwestern China.During the MWP,the stronger Asian summer monsoon and the northward movement of the rain belt led to a dry period in southwestern China and a wet period in northern China.In contrast,it was wet in southwestern China and dry in northern China during the LIA.In addition,after the Jing-Kang event(JK event,AD1127)occurred at the end of the Northern Song dynasty,the political and economic center of China migrated to southern China for the first time,which changed the population distribution pattern of larger population in the north and smaller population in the south.Therefore,the expansion of KRD in southwestern China was exacerbated in the MWP due to the change of climate in southwestern China,the migration of a large number of people,wars,the large-scale reclamation of arable land,and the cultivation of large areas of crops. | Chaojun CHEN Daoxian YUAN Hai CHENG Tsailuen YU Chuanchou SHEN RLawrence EDWARDS Yao WU Siya XIAO Jian ZHANG Tao WANG Ran HUANG Ziqi LIU Tingyong LI Junyun LI | 2021 | Science China Earth Sciences2021，64，10： | 1 |
| 18 | Synthesis and biological activity of certain alkyl 5-(alkoxycarbonyl)-1 H-benzimidazole-2- carbarnates and related derivatives 显示文摘 | Siya R Dean S W Linda L W | 1992 | J Med Chem1992，35，3： | 1 |
| 19 | Transformation of monolayer MoS2 into multiphasic MoTe2: Chalcogen atom-exchange synthesis route显示文摘铝 ditelluride (是重要转变金属 dichalcogenide 的尘埃 2), ,由于它的唯一的性质吸引了可观的兴趣,例如它的小 bandgap 和大 Seebeck 系数。然而,单层尘埃 2 的批生产很少被报导了。在这研究,我们表明合成大域(超过 30 m 的边长度) ,从化学蒸汽的单层尘埃 2 用一条 chalcogen 原子交换合成线路的免职成年的单层瞬间 2 。tellurization 过程的深入的调查表明由 Te 的 S 原子的替换流行地在边和与 alloyed MoSSe 混血儿的形成不同于瞬间 2 薄片的同类的 selenization 的单层瞬间 2, 的谷物边界被开始。而且,我们在转变尘埃 2 格子检测大压缩紧张(约 10%) ,哪个可能在 500 的反应温度从 2H 驾驶阶段转变到 1T? | Qiyi Fang Zhepeng Zhang Qingqing Ji Siya Zhu Yue Gong Yu Zhang Jianping Shi Xiebo Zhou Lin Gu Qian Wang Yanfeng Zhang | 2017 | Nano Research2017，10，8： | 1 |
| 20 | Synthesis of 2-thiobenzimidazole derivatives as potential antifilarial agents显示文摘 | Siya R Dean S Leroy B | 1985 | Chem Heterocycl Compd1985，22，5： | 1 |
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