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| 1 | Heavy metal pollution abatement using rock phosphate mineral显示文摘 | Sona Saxena S.F. D’Souza | 2005 | Environment International2005,,2: | 3 |
| 2 | Relevance of low viral load in haemodialysed patients with chronic hepatitis C virus infection显示文摘AIM: To identify predictors of sustained virological response in hemodialysed patients treated by PEGinterferon α for chronic hepatitis C, genotype 1.METHODS: The sustained virological response(SVR) rate, IL28 B genotype, IFNL4 genotype, initial viral load(IVL) and other pretreatment variables in 39 endstage renal disease patients(ESRD) on maintenance haemodialysis(HD) infected with hepatitis C virus(HCV), genotype 1b, were compared with a control group of 109 patients with normal kidney function treated within the same period. All the patients were treatment nave and had well compensated liver disease. The ESRD patients received 135 μg of PEGylated interferon α-2a(Peg IFN-α) weekly and a reduced dose of ribavirin(RBV) was administered to 23/39 patients with an initial haemoglobin level > 10 g/d L. Control group patients were given standard doses of Peg IFN-α and RBV. SVR was assessed as HCV RNA negativity 24 wk post-treatment. A t-test or ANOVA were used for comparisons of the means and a χ2 testcompared the frequencies.Logistic regression was used to determine significant predictors of SVR.Cutoff values for continuous variables were obtained from Receiver Operating Characteristic analysis.RESULTS:The distribution of IL28B rs12979860 CC,CT and TT genotypes in the ESRD group was 28.2%,64.1%and 7.7%,respectively,and 19.3%,62.4%and18.3%in the controls.The IFNL4 genotype was in almost absolute linkage disequlibrium with IL28B.The proportion of patients with a low IVL(<600000 IU/m L)was significantly higher in the ESRD group than in the controls(28/39,71.8%vs 51/109,46.8%,P=0.009),as was the proportion of patients with low IVL in IL28B CC carriers compared with non-CC carriers in the ESRD group(10/11,90.9%vs 18/28,64.3%,P=0.0035).This difference was not found in the controls(7/22,31.8%vs 44/87,50.6%,P=0.9).The overall SVR rate was 64.1%(25/39)in the ESRD group and 50.5%(55/109)in the control group(P=0.19).11/11(100%)and 19/22(86.4%)IL28B CC patients achieved SVR in the ESRD and control groups,respectively.A statistically significant association between SVR and IL28B and IFNL4 variants was found in both groups.The ESRD patients who achieved SVR showed the lowest IVL[median 21000,interquartile range(IQR):6000-23000IU/m L],compared with ESRD individuals without SVR(1680000,IQR:481000-6880000,P=0.001),controls with SVR(387000,IQR:111000-1253000)and controls without SVR(905000,IQR:451000-3020000).In ESRD,an IVL<600000 IU/m L was strongly associated with SVR:24/28(85.7%)patients who achieved SVR had viraemia below this threshold.CONCLUSION:Haemodialysis decreases the viral load,especially in IL28B CC genotype carriers.A low IVL was the strongest predictor of SVR in ESRD patients identified in multivariate analysis. | Jan Sperl Sona Frankova Renata Senkerikova Magdalena Neroldova Vaclav Hejda Miroslava Volfova Dusan Merta Ondrej Viklicky Julius Spicak Milan Jirsa | 2015 | World Journal of Gastroenterology2015,21,18: | 2 |
| 3 | Evaluation of mannitol effect in patients with acute hepatic failure and acute-on-chronic liver failure using conventional MRI,diffusion tensor imaging and in-vivo proton MR spectroscopy显示文摘AIM:To evaluate the effect of an intravenous bolus of mannitol in altering brain metabolites, brain water content, brain parenchyma volume, cerebrospinal fluid (CSF) volume and clinical signs in controls and in patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF), by comparing changes in conventional magnetic resonance imaging (MRI), in vivo proton magnetic resonance spectroscopy (PMRS) and diffusion tensor imaging (DTI) before and after its infusion.METHODS: Five patients each with ALF and ACLF in grade 3 or 4 hepatic encephalopathy and with clinical signs of raised intracranial pressure were studied along with five healthy volunteers. After baseline MRI, an intravenous bolus of 20% mannitol solution was given over 10 min in controls as well as in patients with ALF and ACLF. Repeat MRI for the same position was acquired 30 min after completing the mannitol injection. RESULTS: No statistically significant difference was observed between controls and patients with ALF and ACLF in metabolite ratios, DTI metrics and brain volume or CSF volume following 45 min of mannitol infusion. There was no change in clinical status at the end of post-mannitol imaging. CONCLUSION: The osmotic effect of mannitol did not result in significant reduction of brain water content, alteration in metabolite ratios or any change in the clinical status of these patients during or within 45 min of mannitol infusion. | Vivek A Saraswat Sona Saksena Kavindra Nath Pranav Mandal Jitesh Singh M Albert Thomas Ramkishore S Rathore Rakesh K Gupta | 2008 | World Journal of Gastroenterology2008,14,26: | 2 |
| 4 | Cytosolic triacylglycerol biosynthetic pathway inoilseeds, molecular cloning and expression of peanut eytosolic diacylglycerol acyltransferase显示文摘 | Saha S Enugutti B Sona Rajakumari | | Plant Physiology0,141,: | 1 |
| 5 | Beyond the Technology Adoption:Technology Readiness Effects on Post-Adoption Behavior显示文摘 | Sona M Han K | 2011 | Journal of Business Research2011,64,11: | 1 |
| 6 | On the measurement of power via a superheterodyne spectrum analyzer 显示文摘 | Matteo Bertocco Alessandro Sona | 2006 | IEEE Transactions on Instrumentation and Measurement2006,55,5: | 1 |
| 7 | RESURF LDMOSFET with a trench for SOI power integrated circuits显示文摘 | Sona W S Sohnb Y H Choia S Y | | 0,,05: | 1 |
| 8 | Structures and antitumor activity of the polysaccharides isolated from fruiting body and the growing fermentation of mycelium of Canoderma Lucidum显示文摘 | SONA Y OKUDA R WADA N | 1985 | J Agric Biol Chem1985,49,: | 1 |
| 9 | Cerrical lymph node metastasis ases sment of radiologic criteria显示文摘 | Michel WM Herberty Sonas A | 1990 | Radiology1990,177,: | 1 |
| 10 | Moderating effects of thegeometry of reservoirs on the relation between urban land use and water quality显示文摘 | HWANG S J LEE S W SONA J Y | 2007 | Landscape and Urban Planning2007,82,4: | 1 |
| 11 | Variation of WC grain shape with carbon content in the WC-Co alloys during liquidphase sintering显示文摘 | Kim Sona Han Seok-Hee Park Jong-Ku | 2003 | Seripta Materialia2003,48,5: | 1 |
| 12 | Enhanced electrochemical properties of SnO2 anode by AlPO4 coating显示文摘 | KIMA T J SONA D CHOB J PARK B YANG H | 2004 | Electrochimica Acta2004,49,: | 1 |
| 13 | Com- parison of forehead and digit oximetry in surgical/trauma patients at risk for decreased peripheral perfusion 显示文摘 | SCHALLOM L SONA C MCSWEENEY M | 2007 | Heart & Lung:The Journal of Acute and Critical Care2007,36,3: | 1 |
| 14 | Habitat Destruction in a Simple Predator–Prey Patch Model: How Predators Enhance Prey Persistence and Abundance显示文摘 | Sona Prakash André M. de Roos | 2002 | Theoretical Population Biology2002,,3: | 1 |
| 15 | Efficacy and safety of an insulin protocol in a surgical ICU显示文摘 | Taylor B E Schallom M E Sona C S | 2006 | J Am Surg2006,202,1: | 1 |
| 16 | RESURF LDMOSFET with a trench for SOI power integrated circuits显示文摘 | SONA W S SOHNB Y H CHOIA S Y | 2004 | Microelectron J2004,35,5: | 1 |
| 17 | Russulaceae ( Russulales, Agaricomycotina, fungi ) in the thermophilous oak forests of W Slovakia 显示文摘 | SLAVOMIR A SONA J MILAN V | 2013 | Scripta Botanica Belgica2013,51,: | 1 |
| 18 | Network approach to understanding the organization of and the consequence of targeted leader removal on an end-oriented task显示文摘 | Sumana ANNAGIRI Swetashree KOLAY Bishwarup PAUL Chandan SONA | 2017 | Current Zoology2017,63,3: | 1 |
| 19 | Recent advances inquantitative PCR(qPCR) applications in food microbiology 显示文摘 | Florence P Helene F Sona P | 2011 | Food Microbiology2011,28,5: | 1 |
| 20 | The impact of a simple,low-cost oral care protocol on ventilator-associated pneumoniarates in a surgical intensive care unit显示文摘 | Sona CS Zack JE Schallom ME | | 0,,01: | 1 |