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| 1 | 疫苗引入前苏州地区儿童肺炎链球菌的分子流行病学特征研究显示文摘目的了解苏州地区在7价肺炎链球菌结合疫苗(7 heptavalent pneumococcal conjugate vaccine,PCV7)引入前,不同临床治疗压力下肺炎链球菌分离株的耐药特征、血清分型及国际流行耐药克隆株(pneumococ-cal molecular epidemiology network,PMEN)的流行情况。方法收集2006年3月-2007年3月期间苏州大学附属儿童医院住院治疗的呼吸道感染儿童(病例组)和非呼吸道感染儿童(对照组)中分离的肺炎链球菌134株,进行抗生素敏感性分析和血清型分型,并对其中86株大环内酯类药物菌株进行基因分型。结果病例组抗生素的使用率高于对照组(x2=111.19,P〈0.001)。病例组分离的菌株血清型以19F、19A和14为主,对照组菌株常见的血清型为6B、19F和23F,两组PCV7血清型覆盖率分别为58.3%和68.1%。对照组菌株对常用抗生素的敏感性均高于病例组(均有P〈0.05)。菌株基因分型共检测出10种PMEN克隆株,最常见的为Taiwan19F-14克隆株。PMEN克隆株对常用抗菌药物的不敏感率高于非PMEN克隆株。结论在我国引入PCV7前,在抗生素等治疗压力下,苏州地区肺炎链球菌的耐药情况严重,以Taiwan19F-14克隆株流行为主,多种PMEN克隆株并存。 | 耿倩 张涛 陈蓉 丁云芳 郝创利 林玉尊 Steven Black 赵根明 | 2014 | 中华疾病控制杂志2014，18，5： | 6 |
| 2 | Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site显示文摘 | Egan RM Yorkey C Black R Loh WK Stevens JL Woodward JG | 1996 | J Immunol1996，157，6： | 1 |
| 3 | Professionalism in medical education: The development and validation of a survey in strument to assess attitudes toward professionalism 显示文摘 | George F Black ALL Steven A Melnick | 2007 | Medical teach- er2007，29，： | 1 |
| 4 | Clinical outcomes of single versus staged hybrid repair for thoracoabdominal aortic aneurysm显示文摘 | Ludovic Canaud Alan Karthikesalingam Dan Jackson Lynne Cresswell Michael Cliff S. Sheraz Markar Gary Maytham Steven Black Matt Thompson | 2013 | Journal of Vascular Surgery2013，，： | 1 |
| 5 | C-Reactive Protein Causes Downregulation of Vascular Angiotensin Subtype 2 Receptors and Systolic Hypertension in Mice显示文摘 | Wanpen Vongpatanasin Gail D. Thomas Randall Schwartz Lisa A. Cassis Sherri Osborne-Lawrence Lisa Hahner Linda L. Gibson Steven Black David Samols Philip W. Shaul | 2007 | Circulation2007，，8： | 1 |
| 6 | The effect of 3 versus 6 years of Zoledronic acid treatment of osteoporosis: A randomized extension to the HORIZON‐Pivotal Fracture Trial (PFT)显示文摘 | Dennis M Black Steven Boonen Jane A Cauley Steven R Cummings Kurt Lippuner Ping Chung Leung Ruvie Lou Maria Martinez Mary Ellen Ruzycky Richard Eastell | 2012 | J Bone Miner Res2012，，12： | 1 |
| 7 | Health-related quality of life and treatment of postmenopausal osteoporosis: Results from the HORIZON-PFT显示文摘 | Philip N. Sambrook Stuart L. Silverman Jane A. Cauley Chris Recknor Melvin Olson Guoqin Su Steven Boonen Dennis Black Jonathan D. Adachi | 2011 | Bone2011，，6： | 1 |
| 8 | Pediatric Obesity and Gallstone Disease显示文摘 | Corinna Koebnick Ning Smith Mary Helen Black Amy H. Porter Bradley A. Richie Sharon Hudson Deborah Gililland Steven J. Jacobsen George F. Longstreth | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，3： | 1 |
| 9 | Usefulness of the vasodilator minoxidil in resistant hypertension显示文摘 | R Neil A Black Steven J Hunter A Brew Atkinson | 2007 | Journal of Hypertension2007，，5： | 1 |
| 10 | 卒中和短暂性脑缺血发作患者的卒中预防指南(续前)美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南显示文摘5非心源性栓塞性卒中或TIA的抗栓治疗
5.1抗血小板药
FDA已批准4种抗血小板药用于预防卒中或TIA患者的血管事件:阿司匹林、阿司匹林/双嘧达莫联合应用、氯吡格雷和噻氯匹定。平均而言,这些药物能使卒中、MI或死亡的船降低22%,但这些药物之间存在重要的差异,这会直接影响治疗的选择。 | 洪道俊 黄招君 李小兵 周美鸿 吴成斯 王博 卢艺 吴裕臣 Walter N. Kernan Bruce Ovbiagele Henry R. Black Dawn M. Bravata Marc I. Chimowitz Michael D. Ezekowitz Margaret C. Fang Marc Fisher Karen L. Furie Donald V. Heck S. Claiborne (Clay) Johnston Scott E. Kasner Steven J. Kittner Pamela H. Mitchell 2. .. Michael wl Rich DeJuran .Nchardson Lee H. Schwamm John A. Wilson | 2014 | 国际脑血管病杂志2014，22，12： | 1 |
| 11 | The Importance of Active Surveillance in the Assessment of Vaccine Safety显示文摘Vaccines are among the most effective public health interventions(1).However,vaccines can potentially cause harm.To minimize risk,proactive regulation of drugs and vaccines was implemented globally beginning in the 1950s.With new requirements for safety evaluation also came new regulations for routine post-marketing surveillance. | Steven Black | 2019 | China CDC weekly2019，1，2： | 1 |
| 12 | IGF-1 induced vascular endothelial growth factor secretion in head and neck squamous cell carcinoma显示文摘 | Mark G. Slomiany Leigh Ann Black Megan M. Kibbey Terry A. Day Steven A. Rosenzweig | 2006 | Biochemical and Biophysical Research Communications2006，，3： | 1 |
| 13 | Current management of high-energy tibial plateau fractures显示文摘 | Robert D. Zura James A. Browne Molly D. Black Steven A. Olson | 2007 | Current Orthopaedics2007，，3： | 1 |
| 14 | Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures显示文摘 | Dennis M Black Steven R Cummings David B Karpf Jane A Cauley Desmond E Thompson Michael C Nevitt Douglas C Bauer Harry K Genant William L Haskell Robert Marcus Susan M Ott James C Torner Sara A Quandt Theodore F Reiss Kristine E Ensrud | 1996 | The Lancet1996，，9041： | 1 |
| 15 | Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Philip B. Gorelick Angelo Scuteri Sandra E. Black Charles DeCarli Steven M. Greenberg Costantino Iadecola Lenore J. Launer Stephane Laurent Oscar L. Lopez David Nyenhuis Ronald C. Petersen Julie A. Schneider Christophe Tzourio Donna K. Arnett David A. Ben | 2011 | Stroke2011，，： | 1 |
| 16 | Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs显示文摘 | Steven R. Cummings David B. Karpf Fran Harris Harry K. Genant Kristine Ensrud Andrea Z. LaCroix Dennis M. Black | 2001 | The American Journal of Medicine2001，，： | 1 |
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