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| 1 | 新型农村合作医疗对农民卫生服务可及性影响的研究——福建省罗源县、柘荣县新农合定性研究显示文摘目的:为研究新型农村合作医疗(新农合,NCMS)的实施对农民卫生服务可及性的影响。方法:使用定性研究方法,包括半结构式访谈、关键人物访谈、专题小组讨论及矩阵排序(Matrix Ranking)对罗源、柘荣两个县55名农民、12名县及乡镇医疗机构管理人员和4名卫生行政部门管理人员进行访谈。结果:三方均认为新型农村合作医疗的实施使农民的卫生服务可及性得到改善,农民认为补偿比例的提高、门诊可报销和老年人特殊补偿政策是矩阵排序的前3个优先关注的问题。结论:新型农村合作医疗提高农民卫生服务的可及性,一定程度降低农民医疗经济负担。 | 陈烈平 赖爱华 黄渊清 刘秋燕 Corinna Blume | 2008 | 中国农村卫生事业管理2008，28，5： | 15 |
| 2 | Support-Vector Networks显示文摘 | Corinna Cortes Vladimir Vapnik | 1995 | Machine Learning1995，，3： | 13 |
| 3 | Repression of the Arabidopsis thaliana Jasmonic Acid/Ethylene-Induced Defense Pathway by TGA-Interacting Glutaredoxins Depends on Their C-Terminal ALWL Motif显示文摘Glutaredoxins 是小热马厩 oxidoreductases 从谷胱甘肽(GSH ) 的转移电子到氧化半胱氨酸残余,从而贡献蛋白质正直和规定。在 Arabidopsis thaliana,花的 glutaredoxins ROXY1 和 ROXY2 和导致病原体的 ROXY19/GRX480 与 TGACG (TGA ) 主题绑定家庭的 bZIP 抄写因素交往。ROXY1, ROXY2,和 TGA 因素 PERIANTHIA, TGA9,和 TGA10 在花的开发起必要作用。相反,宫外地否定地表示了 ROXY19/GRX480 调整 /ethylene (et ) 导致了的 jasmonic 酸(JA ) 的表示通过要求 clade II 抄写因素 TGA2, TGA5,或 TGA6 的未知机制的防卫基因。这里,我们报导 21 中的至少 17 个打编码为 Arabidopsis 染色体的植物特定的 glutaredoxins 在一个 yeast-two-hybrid 系统与 TGA2 交往。调查他们的能力防碍 JA/ET-induced 基因的表示,我们开发了一个短暂表示系统。ORA59 (OCTADECANOID 应答的 ARABIDOPSIS AP2/ERF-domain 蛋白质 59 ) 的激活由抄写因素 EIN3 (乙烯 INSENSITVE 3 ) 的倡导者被共同表示的 ROXY19/GRX480 镇压。抑制在 ROXY19/GRX480 的 C 终点取决于 L **LL 主题。这个通常认为的蛋白质相互作用领域最近被描述为为 TGA/ROXY 相互作用是必要的。17 测试 ROXY 蛋白质中的十个压制了 ORA59 倡导者活动,它与 C 终端 ALWL 主题的存在相关,它为在花开发的 ROXY1 功能是必要的。ROXY19/GRX480-mediated 压抑取决于 GSH 有约束力的地点,建议 TGA 因素或迄今为止未知的目标蛋白质的那氧化还原作用修正为 ORA59 的抑制是重要的倡导者活动。 | Mark Zander Shuxia Chen Julia Imkampe Corinna Thurow Christiane Gatz | 2012 | Molecular Plant2012，5，4： | 11 |
| 4 | Arrhythmogenic ventricular cardiomyopathy:A paradigm shift from right to biventricular disease显示文摘Arrhythmogenic ventricular cardiomyopathy(AVC) isgenerally referred to as arrhythmogenic right ventricu-lar(RV) cardiomyopathy/dysplasia and constitutesan inherited cardiomyopathy.Affected patients maysuccumb to sudden cardiac death(SCD),ventriculartachyarrhythmias(VTA) and heart failure.Geneticstudies have identified causative mutations in genesencoding proteins of the intercalated disk that lead toreduced myocardial electro-mechanical stability.Theterm arrhythmogenic RV cardiomyopathy is somewhatmisleading as biventricular involvement or isolated leftventricular(LV) involvement may be present and thus abroader term such as AVC should be preferred.The di-agnosis is established on a point score basis accordingto the revised 2010 task force criteria utilizing imagingmodalities,demonstrating fibrous replacement throughbiopsy,electrocardiographic abnormalities,ventricu-lar arrhythmias and a positive family history includingidentification of genetic mutations.Although severarisk factors for SCD such as previous cardiac arrest,syncope,documented VTA,severe RV/LV dysfunctionand young age at manifestation have been identified,risk stratification still needs improvement,especially inasymptomatic family members.Particularly,the roleof genetic testing and environmental factors has to befurther elucidated.Therapeutic interventions include re-striction from physical exercise,beta-blockers,sotalol,amiodarone,implantable cardioverter-defibrillators andcatheter ablation.Life-long follow-up is warranted insymptomatic patients,but also asymptomatic carriersof pathogenic mutations. | Ardan M Saguner Corinna Brunckhorst Firat Duru | 2014 | World Journal of Cardiology2014，6，4： | 10 |
| 5 | Support-Vector Networks显示文摘 | Corinna Cortes Vladimir Vapnik | | Machine Learning0，，： | 10 |
| 6 | 人类免疫缺陷病毒感染者抑郁障碍、自杀风险和日常生活能力的研究显示文摘目的研究人类免疫缺陷病毒(H IV)感染者抑郁症和自杀观念的流行情况及其与日常生活能力改变的关联。方法对28例H IV阳性者及23例H IV阴性者,用复合性国际诊断用检查提纲中文版调查抑郁症的总发生率和自杀史,用贝克抑郁问卷(BD I)评估当前抑郁障碍及自杀风险的严重程度,用日常生活能力问卷(ADL)评估H IV感染对日常生活能力的影响。结果(1)H IV阳性组和H IV阴性组中分别有22例(79%)和1例(4%)符合抑郁症的诊断标准(P<0.001);H IV阳性组BD I总分[(22.4±12.7)分]高于H IV阴性组[(6.6±7.8)分;P<0.001]。(2)H IV阳性组和H IV阴性组中分别有18例(64%)和2例(9%)有过自杀观念。(3)H IV阳性组ADL总分[(17.1±5.2)分]高于H IV阴性组[(14.0±0.0)分;P<0.001]。(4)BD I与H IV状况的交互作用是有显著贡献(F=23.95,P<0.001)的自变量,抑郁障碍与H IV状况的相互作用是有意义(F=13.29,P=0.001)的预测因子。结论H IV感染的人群中抑郁症的发生率及自杀风险均较高,抑郁的严重程度和日常生活能力受损有显著相关性。 | 于欣 石川 金华 J.Hampton Atkinson Robert Heaton Thomas Marcotte Corinna Young Joseph Sadek 吴尊友 Igor Grant | 2006 | 中华精神科杂志2006，39，2： | 8 |
| 7 | 参加新型农村合作医疗农民就医行为影响因素的定性研究显示文摘[目的]对参加新型农村合作医疗(参合)农民就医行为的定性研究,分析参合农民就医行为变化,了解农民就医行为的异同及主要影响因素。[方法]在罗源和柘荣县,采用半结构式访谈、关键人物访谈和专题小组讨论等定性调查方法,访谈了两县71名农民、卫生服务提供者和卫生管理人员。[结果]调查发现这两县参合农民就医行为的变化不尽一致,柘荣县参合农民的就医行为变化不大,罗源县越来越多的参合农民前往就近乡镇卫生院就医,乡镇卫生院就医条件等成为差别的主要因素。[结论]要继续加大政府投入,加强卫生院的建设,提高乡镇卫生人员的技能和素质,改善农村地区道路交通等基础设施,以促进新农合开展。 | 陈烈平 赖爱华 黄渊清 刘秋艳 Corinna B 吴晨曦 郑鹤 林淑周 | 2008 | 海峡预防医学杂志2008，14，6： | 8 |
| 8 | New spinal robotic technologies显示文摘Robotic systems in surgery have developed rapidly. Installations of the da Vinci Surgical System® (Intuitive Surgical, Sunnyvale, CA,, USA), widely used in urological and gynecological procedures, have nearly doubled in the United States from 2010 to 2017. Robotics systems in spine surgery have been adopted more slowly;however, users are enthusiastic about their applications in this subspecialty. Spinal surgery often requires fine manipulation of vital structures that must be accessed via limited surgical corridors and can require repetitive tasks over lengthy periods of time — issues for which robotic assistance is well-positioned to complement human ability. To date, the United States Food and Drug Administration (FDA) has approved 7 robotic systems across 4 companies for use in spinal surgery. The available clinical data evaluating their efficacy have generally demonstrated these systems to be accurate and safe. A critical next step in the broader adoption of surgical robotics in spine surgery is the design and implementation of rigorous comparative studies to interrogate the utility of robotic assistance. Here we discuss current applications of robotics in spine surgery, review robotic systems FDA-approved for use in spine surgery, summarize randomized controlled trials involving robotics in spine surgery, and comment on prospects of robotic-assisted spine surgery. | Bowen Jiang Tej DAzad Ethan Cottrill Corinna CZygourakis Alex MZhu Neil Crawford Nicholas Theodore | 2019 | Frontiers of Medicine2019，13，6： | 5 |
| 9 | Effects of supplementation of green tea extract on the milk performance of peripartal dairy cows and the expression of stress response genes in the liver显示文摘Background: We hypothesised that supplementation of green tea extract(GTE) in dairy cows during the transition period can attenuate proinflammatory conditions and prevent endoplasmic reticulum(ER) stress in the liver of these cows. Thirty Holstein cows with an average parity of 3.06(± 1.31, SD) were divided into a control group and a group that received a daily amount of 10 g of GTE from d 7 before the calving day and a daily amount of 20 g of GTE from the day of calving until d 7 of lactation.Results: Cows supplemented with GTE did not show differences in energy intake or milk yield in weeks 2–7 of lactation. However, these cows had a lower milk fat concentration and a lower energy corrected milk yield than the control cows and showed a trend of improved energy balance. The relative m RNA concentrations of proinflammatory genes, genes involved in the acute phase reaction and antioxidant genes in the liver in weeks 1, 4 and 7 of lactation were not different between the two groups of cows. The concentrations of α-tocopherol and the Trolox equivalent antioxidant capacity in plasma were not different between the two groups. However, the group supplemented with GTE showed significant reductions of some genes of the unfolded protein response(UPR) in week 1 and a trend of lower liver triacylglycerol(TAG) concentrations in the liver compared to the control group.Conclusions: This study shows that supplementation of GTE in dairy cows lowers the fat concentration in the milk but overall has no effect on the expression of inflammatory genes and the antioxidative status in dairy cows during early lactation. The finding of reduced m RNA levels of genes involved in the UPR at week 1, however, supports other results showing that supplementation of polyphenols could prevent the development of ER stress in the liver of cows during early lactation. The finding of a tendency towards a reduced TAG concentration in the liver of cows supplemented with GTE might be due to an improved energy balance in these cows. | Denise K.Gessner Corinna Brock Lena M.Hof Erika Most Christian Koch Klaus Eder | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 5 |
| 10 | First report of splenic rupture following deep enteroscopy显示文摘Splenic rupture is a rare complication of diagnostic and therapeutic gastrointestinal endoscopy procedures.Herein,we report for the first time a case of splenic rupture following therapeutic retrograde double-balloon enteroscopy,which occurred in an 85-year-old man who was treated for recurrent mid-intestinal bleeding that resulted from ileal angioectasia.This patient promptly underwent an operation and eventually recovered. | Carlo Maria Girelli Roberta Pometta Corinna Facciotto Roberto Mella Giordano Bernasconi | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，9： | 3 |
| 11 | Fulminant sepsis after liver biopsy:A long forgotten complication?显示文摘We report on a 74-year-old patient with recurrent cholangitis and a large juxtapapillary duodenal diverticulum. Despite drainage of the common bile duct by an endoscopically placed stent, the elevated liver enzymes normalized only partially. To rule out other possible causes of liver injury, a percutaneous liver biopsy was done. After the liver biopsy the patient developed fulminant septic shock and died within 24 h. We discuss the possible causes of the septic shock following percutaneous liver biopsy in our patient and give a concise overview of the literature. | Corinna Claudi Martin Henschel Jürgen Vogel Michael Schepke Erwin Biecker | 2013 | World Journal of Clinical Cases2013，1，1： | 2 |
| 12 | Patterns and Timing in Expression of Early Auxin-Induced Genes Imply Involvement of Phospholipases A (pPLAs) in the Regulation of Auxin Responses显示文摘当 patatin 相关的 phospholipase A (pPLA ) 活动被植物生长素很快在 3min 以内激活,这被知道时,任何东西几乎不这个信号怎么影响象早导致植物生长素的基因的抄写一样的下游的回答或另外的生理的回答被知道。我们为与植物生长素有关的分子、生理的显型在 pPLA 基因家庭的成员与 T-DNA 插入屏蔽了异种。仅仅在九 Arabidopsis thaliana ppla 的击倒的异种显示了明显的组成的植物生长素相关的显型。比作野类型, ppla-III 异种幼苗减少了主要的根长度和增加的侧面的根数字。我们在九 ppla 异种为主要分子的植物生长素回答作为分子的读出测试了导致植物生长素的基因表示并且他们在所有发现植物生长素应答的基因表示的起来规定推迟。在植物生长素处理以后的三十分钟,多达 40% 导致植物生长素的基因的起来规定在变异的幼苗被推迟。我们在 ppla 异种与过分敏感的导致植物生长素的基因表示观察了仅仅一些盒子。当时在三 ppla 异种,它详细被调查,快速的起来规定(象在植物生长素刺激以后的 10min 一样早) 调整植物生长素的基因,被损害的、迟了的 transcriptional 回答是 wild-type-like。这规章或动态的显型一致地与经常影响了一样的基因的推迟的起来规定在不同 ppla 异种被观察。这个缺点没被仍然保持不变的 pPLA 抄本层次影响。这作为到植物生长素发信号的 pPLAs 的一个功能的连接显示 posttranslational 机制。对没有采用抄写规定,触发植物生长素回答的受体的需要被讨论。 | Corinna Labusch Maria Shishova Yunus Effendi Maoyin Li Xuemin Wang Gunther RE. Scherera | 2013 | Molecular Plant2013，6，5： | 2 |
| 13 | Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations:A case report and review of the literature显示文摘Hepatitis B represents a global health threat because its chronic course and sequelae contribute to a high morbidity and mortality. Hepatitis B virus(HBV) infection can be controlled by vaccines, antiviral treatment, and by interrupting transmission. Rare vaccine escape mutants are serious because they eliminate vaccine protection. Here, we present a 74-year-old vaccinated patient with HBV reactivation 11 years after kidney transplantation. The patient was HBV-positive but HBs Ag-negative prior to vaccination 6 years before transplantation. The reactivated virus was HBV genotype F3 with vaccine escape mutations G145 R, P120 Q, and Q129 P. The patient was successfully treated with entecavir. The epidemiological reasons for this subgenotype, which is extremely rare in Western Europe, were unclear. This case illustrates that second-generation vaccines are not always effective in a specific group of patients. | Stefan Schlabe Kathrin van Bremen Souhaib Aldabbagh Dieter Glebe Corinna M Bremer Tobias Marsen Walter Mellin Veronica Di Cristanziano Anna M Eis-Hübinger Ulrich Spengler | 2018 | World Journal of Hepatology2018，10，7： | 2 |
| 14 | Gallstone disease is associated with rectal cancer: a meta-analysis显示文摘 | Corinna Chiong Michael R. Cox Guy D. Eslick | 2012 | Scandinavian Journal of Gastroenterology2012，，5： | 2 |
| 15 | Oxidized LDL Inhibits Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration by an Inhibitory Effect on the Akt/Endothelial Nitric Oxide Synthase Pathway显示文摘 | Emmanouil Chavakis Elisabeth Dernbach Corinna Hermann Ulrich F. Mondorf Andreas M. Zeiher Stefanie Dimmeler | 2001 | Circulation: Journal of the American Heart Association2001，，16： | 2 |
| 16 | A novel method for the in vivo isolation of circulating tumor cellsfrom peripheral blood of cancer patients using a functionalized and structuredmedical wire显示文摘 | Nadia Saucedo-Zeni Steffi Mewes Robert Niestroj Lukasz Gasiorowski David Murawa Piotr Nowaczyk Tatiana Tomasi Ekkehard Weber Grzegorz Dworacki Nils Morgenthaler Heike Jansen Corinna Propping Karolina Sterzynska Wojciech Dyszkiewicz Maciej Zabel Marion Kie | 2012 | International Journal of Oncology2012，，4： | 2 |
| 17 | Chronic pancreatitis and the heart disease:Still terra incognita?显示文摘BACKGROUND It has been suggested that chronic pancreatitis(CP)may be an independent risk factor for development of cardiovascular disease(CVD).At the same time,it seems that congestive heart failure(CHF)and CP share the responsibility for the development of important clinical conditions such as sarcopenia,cachexia and malnutrition due to development of cardiac cachexia and pancreatic exocrine insufficiency(PEI),respectively.AIM To explore the evidence regarding the association of CP and heart disease,more specifically CVD and CHF.METHODS A systematic search of MEDLINE,Web of Science and Google Scholar was performed by two independent investigators to identify eligible studies where the connection between CP and CVD was investigated.The search was limited to articles in the English language.The last search was run on the 1st of May 2019.The primary outcomes were:(1)Incidence of cardiovascular event[acute coronary syndrome(ACS),chronic coronary disease,peripheral arterial lesions]in patients with established CP;and(2)Incidence of PEI in patients with CHF.RESULTS Out of 1166 studies,only 8 were eligible for this review.Studies regarding PEI and CHF showed an important incidence of PEI as well as associated malabsorption of nutritional markers(vitamin D,selenium,phosphorus,zinc,folic acid,and prealbumin)in patients with CHF.However,after substitution of pancreatic enzymes,it seems that,at least,loss of appetite was attenuated.On the other side,studies investigating cardiovascular events in patients with CP showed that,in CP cohort,there was a 2.5-fold higher incidence of ACS.In another study,patients with alcohol–induced CP with concomitant type 3c diabetes had statistically significant higher incidence of carotid atherosclerotic plaques in comparison to patients with diabetes mellitus of other etiologies.Earlier studies demonstrated a marked correlation between the clinical symptoms in CP and chronic coronary insufficiency.Also,statistically significant higher incidence of arterial lesions was found in patients with CP compared to the control group with the same risk factors for atherosclerosis(hypertension,smoking,dyslipidemia).Moreover,one recent study showed that PEI is significantly associated with the risk of cardiovascular events in patients with CP.CONCLUSION Current evidence implicates a possible association between PEI and malnutrition in patients with CHF.Chronic pancreatic tissue hypoxic injury driven by prolonged splanchnic hypoperfusion is likely to contribute to malnutrition and cachexia in patients with CHF.On the other hand,CP and PEI seem to be an independent risk factor associated with an increased risk of cardiovascular events. | Sara Nikolic Ana Dugic Corinna Steiner Apostolos V Tsolakis Ida Marie Haugen Lofman J-Matthias Lohr Miroslav Vujasinovic | 2019 | World Journal of Gastroenterology2019，25，44： | 2 |
| 18 | The Internet and the Public:Online and Offline Political Participation in theUnited Kingdom显示文摘 | Corinna di Gennaro William Dutton | | 0，，02： | 1 |
| 19 | Feedback on household electricity consumption: a tool for saving energy?显示文摘 | Corinna Fischer | 2008 | Energy Efficiency2008，，1： | 1 |
| 20 | The Yersinia Ser/Thr protein kinase YpkA/YopO directly interacts with the small GTPases RhoA and Rac-1显示文摘 | Corinna Barz Thomas N Abahji Konrad Trülzsch Jürgen Heesemann | 2000 | FEBS Letters2000，，： | 1 |
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