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| 1 | Systematic review of the outcomes of surgical resection for intermediate and advanced Barcelona Clinic Liver Cancer stage hepatocellular carcinoma:A critical appraisal of the evidence显示文摘AIM To perform a systematic review to determine the survival outcomes after curative resection of intermediate and advanced hepatocellular carcinomas(HCC).METHODS A systematic review of the published literature was performed using the PubM ed database from 1 st January 1999 to 31 st Dec 2014 to identify studies that reported outcomes of liver resection as the primary curative treatment for Barcelona Clinic Liver Cancer(BCLC) stage B or C HCC. The primary end point was to determine the overall survival(OS) and disease free survival(DFS) of liver resection of HCC in BCLC stage B or C in patients with adequate liver reserve(i.e., Child's A or B status). The secondary end points were to assess the morbidity and mortality of liver resection in large HCC(defined as lesions larger than 10 cm in diameter) and to compare the OS and DFS after surgical resection of solitary vs multifocal HCC.RESULTS We identified 74 articles which met the inclusion criteria and were analyzed in this systematic review. Analysis of the resection outcomes of the included studies were grouped according to(1) BCLC stage B or C HCC,(2) Size of HCC and(3) multifocal tumors. The median 5-year OS of BCLC stage B was 38.7%(range 10.0-57.0); while the median 5-year OS of BCLC stage C was 20.0%(range 0.0-42.0). The collective median 5-year OS of both stages was 27.9%(0.0-57.0). In examining the morbidity and mortality following liver resection in large HCC, the pooled RR for morbidity [RR(95%CI) = 1.00(0.76-1.31)] and mortality [RR(95%CI) = 1.15(0.73-1.80)] were not significant. Within the spectrum of BCLC B and C lesions, tumors greater than 10 cm were reported to have median 5-year OS of 33.0% and multifocal lesions 54.0%.CONCLUSION Indication for surgical resection should be extended to BCLC stage B lesions in selected patients. Further studies are needed to stratify stage C lesions for resection. | Ye Xin Koh Hwee Leong Tan Weng Kit Lye Juinn Huar Kam Adrian Kah Heng Chiow Siong San Tan Su Pin Choo Alexander Yaw Fui Chung Brian Kim Poh Goh | 2018 | World Journal of Hepatology2018，10，6： | 10 |
| 2 | Distinct beneficial effect of Sn on the corrosion resistance of Cr-Mo low alloy steel显示文摘In this work,the beneficial effect of Sn addition on the corrosion resistance mechanism of Cr-Mo low alloy steel was studied.Results demonstrated that Sn improves the corrosion resistance of the steel matrix mainly by influencing the microstructural transformation.Sn addition and the synergistic effect of Sn,Cr,and Mo promote the formation of α-FeOOH,SnO_(2),SnO,Cr(OH)_(3),and molybdates,lead to the improved protection and stability of the rust layer.This synergistic effect also endows the inner rust layer with cation selectivity,preventing the further penetration of Cl-and inhibiting the localized corrosion of steel. | Meihui Sun Xiaojia Yang Cuiwei Du Zhiyong Liu Yong Li Yumin Wu Hongyu San Xiandong Su Xiaogang Li | 2021 | Journal of Materials Science & Technology2021，，22： | 6 |
| 3 | Predicting Cirrhosis Risk Based on the Level of Circulating Hepatitis B Viral Load显示文摘 | Uchenna H. Iloeje Hwai–I. Yang Jun Su Chin–Lan Jen San–Lin You Chien–Jen Chen | 2006 | Gastroenterology2006，，3： | 4 |
| 4 | Salidroside Reduces PDE2A Expression by Down-regulating p53 in Human Embryonic Lung Fibroblasts显示文摘Salidroside(SAL) is a glucoside of tyrosol and a key constituent of Rhodiola rosea L. The diverse pharmacological activities of SAL include anti-inflammatory, cardioprotective, and neuroprotective effects(1)Our previous investigation showed that the anti-aging effects of SAL involve reductions of the levels of advanced glycation end products in a D-galactose induced mouse model(2)Additionally. | XING Wen Min CHEN Sha Sha WANG San Ying GAO Wen Yan WAN Xiao Qing SU Hui Li YANG Yi ZHANG Jing YAN Jing MAO Gen Xiang | 2019 | Biomedical and Environmental Sciences2019，32，2： | 3 |
| 5 | Changes in Serum Levels of HBV DNA and Alanine Aminotransferase Determine Risk for Hepatocellular Carcinoma显示文摘 | Chuen–Fei Chen Wen–Chung Lee Hwai–I. Yang Hung–Chuen Chang Chin–Lan Jen Uchenna H. Iloeje Jun Su Chuhsing K. Hsiao Li–Yu Wang San–Lin You Sheng–Nan Lu Chien–Jen Chen | 2011 | Gastroenterology2011，，4： | 3 |
| 6 | Association between Vitamin D Levels and the Risk of Metabolic Syndrome in a Rural Chinese Population显示文摘Metabolic syndrome(MS)is a cluster of metabolic abnormalities that include obesity,dyslipidemia,hyperglycemia,and high blood pressure(BP)[1].Previous studies have shown that the prevalence of MS is increasing in both developing and developed countries[2].Currently,about a quarter of the adult population worldwide have MS,which has become a serious global public health problem. | SUN Hua Lei LONG Shao Rong FU San Xian CHEN Gai Yun WANG Ya Juan LIANG Rui WANG Su Fan ZHANG Li Ke ZHOU Li Wei LU Quan Jun LI Wen Jie | 2021 | Biomedical and Environmental Sciences2021，34，4： | 2 |
| 7 | Fe atoms anchored on defective nitrogen doped hollow carbon spheres as efficient electrocatalysts for oxygen reduction reaction显示文摘Defective electrocatalysts,especially for intrinsic defective carbon,have aroused a wide concern owing to high spin and charge densities.However,the designated nitrogen species favorable for creating defects by the removal of nitrogen,and the influence of defects for the coordination structure of active site and oxygen reduction reaction(ORR)activity have not been elucidated.Herein,we designed and synthesized a pair of electrocatalysts,denoted as Fe-N/C and Fe-ND/C for coordination sites of atomic iron-nitrogen and iron-nitrogen/defect configuration embedded in hollow carbon spheres,respectively,through direct pyrolysis of their corresponding hollow carbon spheres adsorbed with Fe(acac)3.The nitrogen defects were fabricated via the evaporation of pyrrolic-N on nitrogen doped hollow carbon spheres.Results of comparative experiments between Fe-N/C and Fe-ND/C reveal that Fe-ND/C shows superior ORR activity with an onset potential of 30 mV higher than that of Fe-N/C.Fe-ND sites are more favorable for the enhancement of ORR activity.Density functional theory(DFT)calculation demonstrates that Fe-ND/C with proposed coordination structure of FeN_(4-x)(0 | Panpan Su Wenjuan Huang Jiangwei Zhang Utsab Guharoy Qinggang Du Qiao Sun Qike Jiang Yi Cheng Jie Yang Xiaoli Zhang Yongsheng Liu San Ping Jiang Jian Liu | 2021 | Nano Research2021，14，4： | 2 |
| 8 | Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death显示文摘 | Jin–De Chen Hwai–I. Yang Uchenna H. Iloeje San–Lin You Sheng–Nan Lu Li–Yu Wang Jun Su Chien–An Sun Yun–Fan Liaw Chien–Jen Chen | 2010 | Gastroenterology2010，，5： | 2 |
| 9 | Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19显示文摘Objective The coronavirus disease 2019(COVID-19) pandemic continues to present a major challenge to public health. Vaccine development requires an understanding of the kinetics of neutralizing antibody(NAb) responses to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods In total, 605 serum samples from 125 COVID-19 patients(from January 1 to March 14, 2020)varying in age, sex, severity of symptoms, and presence of underlying diseases were collected, and antibody titers were measured using a micro-neutralization assay with wild-type SARS-CoV-2.Results NAbs were detectable approximately 10 days post-onset(dpo) of symptoms and peaked at approximately 20 dpo. The NAb levels were slightly higher in young males and severe cases, while no significant difference was observed for the other classifications. In follow-up cases, the NAb titer had increased or stabilized in 18 cases, whereas it had decreased in 26 cases, and in one case NAbs were undetectable at the end of our observation. Although a decreasing trend in NAb titer was observed in many cases, the NAb level was generally still protective.Conclusion We demonstrated that NAb levels vary among all categories of COVID-19 patients. Longterm studies are needed to determine the longevity and protective efficiency of NAbs induced by SARS-CoV-2. | LI Ling Hua TU Hong Wei LIANG Dan WEN Chun Yan LI An An LIN Wei Yin HU Ke Qi HONG Wen Shan LI Yue Ping SU Juan ZHAO San Tao LI Wei YUAN Run Yu ZHOU Ping Ping HU Feng Yu TANG Xiao Ping KE Chang Wen KE Bi Xia CAI Wei Ping | 2021 | Biomedical and Environmental Sciences2021，34，12： | 1 |
| 10 | Design of a capacitive-sensor signal processing system with high accuracy and short conversiontime显示文摘 | Hou Ansang Su San Su Xiaoping | 2005 | Sensors and Actuators A2005，119，： | 1 |
| 11 | Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death显示文摘 | Jin–De Chen Hwai–I. Yang Uchenna H. Iloeje San–Lin You Sheng–Nan Lu Li–Yu Wang Jun Su Chien–An Sun Yun–Fan Liaw Chien–Jen Chen | 2010 | Gastroenterology2010，，5： | 1 |
| 12 | A one-model approach to congestion in data envelopment analysis显示文摘 | W.W.Cooper Hong hui Deng Zhimin M.Huang Su san X.Li | | 0，，04： | 1 |
| 13 | Changes in Serum Levels of HBV DNA and Alanine Aminotransferase Determine Risk for Hepatocellular Carcinoma显示文摘 | Chuen–Fei Chen Wen–Chung Lee Hwai–I. Yang Hung–Chuen Chang Chin–Lan Jen Uchenna H. Iloeje Jun Su Chuhsing K. Hsiao Li–Yu Wang San–Lin You Sheng–Nan Lu Chien–Jen Chen | 2011 | Gastroenterology2011，，4： | 1 |
| 14 | Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death显示文摘 | Jin–De Chen Hwai–I. Yang Uchenna H. Iloeje San–Lin You Sheng–Nan Lu Li–Yu Wang Jun Su Chien–An Sun Yun–Fan Liaw Chien–Jen Chen | 2010 | Gastroenterology2010，，5： | 1 |
| 15 | Terminal care for per- sons with advanced dementia in the nursing home and home care settings 显示文摘 | SU San MITCHELL L Park P S | 2004 | Journal of Palliative Medicine2004，，6： | 1 |
| 16 | Three-Year Outcome of Sirolimus -Eluting Versus Bare-Metal Stents for the Treatment of ST-Segment Elevation Myocardial Infarction (from the MISSION! Intervention Study)显示文摘 | Jael Z. Atary Bas L. van der Hoeven Su San Liem J. Wouter Jukema Johanna G. van der Bom Douwe E. Atsma Marianne Bootsma Katja Zeppenfeld Ernst E. van der Wall Martin J. Schalij | 2010 | The American Journal of Cardiology2010，，1： | 1 |
| 17 | Evaluation of abdominal ultrasonography mass screening for hepatocellular carcinoma in Taiwan显示文摘 | Yen‐Po Yeh Tsung‐Hui Hu Po‐Yuan Cho Hsiu‐Hsi Chen Amy Ming‐Fang Yen Sam Li‐Sheng Chen Sherry Yueh‐Hsia Chiu Jean Ching‐Yuan Fann Wei‐Wen Su Yi‐Jen Fang Shih‐Tien Chen Hsiao‐Ching San Hung‐Pin Chen Chao‐Sheng Liao | 2014 | Hepatology2014，，5： | 1 |
| 18 | A Survey on Sensor Networks显示文摘 | Akyildiz F Su W San Y | 2002 | IEEE Communications Magazine2002，40，8： | 1 |
| 19 | Riesgo de fenómenos tromboembólicos en pacientes con enfermedad inflamatoria intestinal显示文摘 | Cristina Suárez Ferrer María Isabel Vera Mendoza Leticia Amo San Román Yago González Lama Marta Calvo Moya Mercedes García Casas Luis Abreu García | 2012 | Gastroenterologia y Hepatologia2012，，9： | 1 |
| 20 | The Traditional Herbal Medicine, Dangkwisoo-San, Prevents Cerebral Ischemic Injury through Nitric Oxide-Dependent Mechanisms显示文摘 | Ji Hyun Kim Sun Haeng Park Young Whan Kim Jung Min Ha Sun Sik Bae Guem San Lee Su In Cho Byung Tae Choi Hwa Kyoung Shin | 2011 | Evidence-Based Complementary and Alternative Medicine2011，，： | 1 |
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