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| 1 | Occurrence and distribution of hydroxylated isoprenoid glycerol dialkyl glycerol tetraethers(OH-GDGTs) in the Han River system, South Korea显示文摘We investigated the occurrence and distribution of terrestrial-derived hydroxylated isoprenoid glycerol dialkyl glycerol tetraethers(OH-GDGTs) in the Han River system and their potential impact on the application of the ring index of OH-GDGTs(RI-OH) as a sea surface temperature(SST) proxy in the eastern Yellow Sea. Thereby, we analyzed various samples collected along the Han River and from its surrounding areas(South Korea, n = 34). The OHGDGTs were found in all samples investigated. OH-GDGT-0 was the dominant OH-GDGT component in the estuary and marine samples while OH-GDGT-2 was generally dominant in the soils, the lake sediments and the river suspended particulate matter(SPM). Our results thus suggests a possible warm bias of the RI-OH-derived summer SSTs in the coastal zone to which a large amount of terrestrial organic matter is being supplied. Further studies are necessary to better assess the applicability of the RI-OH proxy in the eastern Yellow Sea. | Sujin Kang Kyoung-Hoon Shin Jung-Hyun Kim | 2017 | Acta Geochimica2017，36，3： | 3 |
| 2 | In situ observation of hydroxyapatite nanocrystal formation from amorphous calcium phosphate in calcium - rich solutions 显示文摘 | Kim Sujin Ryu Hyun -Seung Shin Hyunho | 2005 | Materials Chemistry and Physics2005，91，23： | 1 |
| 3 | In situ observation of hydroxyapatite nanocrystal formation from amorphous calcium phosphate in calcium -rich solutions显示文摘 | Sujin Kim Hyun-Seung Ryu Hyunho Shin | 2005 | Materials Chemistry and Physics2005，91，： | 1 |
| 4 | 在 colorectal 癌症的维生素 D 的新兴的角色显示文摘 Colorectal cancer is a common cancer and the fourth leading cause of death in Korea. The incidence and mortality of colorectal cancer varies according to risk factors, such as age, family history, genetic history, food habits, and physical activities. Some studies have focused on the association between vitamin D and colorectal cancer. Today, there is growing evidence that high vitamin D intake and a plasma level of 25(OH)D3 reduce the incidence of colorectal cancer by modifying cancer angiogenesis, cell apoptosis, differentiation, and proliferation. Taken together, these results suggest that vitamin D supplementation alone, or in combination with anti-cancer agents, might reduce the incidence of colorectal cancer. In this review, we discuss the function and mechanism of vitamin D including the effect of vitamin D on colorectal cancer. | Wonmo Kang Sujin Lee Eunyi Jeon Kook-Hyun Kim Jun-Hyeog Jang | 2011 | World Journal of Gastrointestinal Oncology2011，3，8： | 1 |
| 5 | Identification of ROS1 rearrangement in gastric adenocarcinoma显示文摘 | Jeeyun Lee Seung Eun Lee So Young Kang In‐Gu Do Sujin Lee Sang Yun Ha Jeonghee Cho Won Ki Kang Jiryeon Jang Sai‐Hong Ignatius Ou Kyoung‐Mee Kim | 2013 | Cancer2013，，9： | 1 |
| 6 | Osteopontin splice variants differentially modulate the migratory activityof hepatocellular carcinoma cell lines显示文摘 | Sujin Chae Hyoung-Oh Jun Eun Lee Suk-Jin Yang Dong Lee Joon Jung Kyung Park Young Yeom Kyu-Won Kim | 2009 | International Journal of Oncology2009，，6： | 1 |
| 7 | Design of fibronectin type III domains fused to an elastin-like polypeptide for the osteogenic differentiation of human mesenchymal stem cells显示文摘Extracellular matrix(ECM)including fibronectin(FN)and elastin plays a pivotal role in providing a microenvironment to support tissue regeneration in stem cell therapy.To develop a novel biomimetic ECM for stem cell differentiation,we engineered FN type III 9 and 10 domains fused to elastin-like polypeptides(FN-ELPs).The recombinant FN-ELP fusion protein was expressed in Escherichia coli and purified by inverse transition cycling.Human mesenchymal stem cells(hMSCs)cultured on plates coated with FN-ELP had significantly greater adhesion activity and proliferation than cells grown on non-coated plates.FN-ELP induced the osteogenic differentiation by elevating alkaline phosphatase(ALP)and mineralization activity of hMSCs.Furthermore,the osteogenic marker gene expressions of ALP,collagen type I(Col I),osteopontin(OPN),and transcriptional coactivator with a PDZ-binding motif(TAZ)were increased in hMSCs cultured on plates coated with FN-ELP.We reported a novel biomimetic ECM with potential for bone regeneration that promotes the osteogenic differentiation of hMSCs. | Sujin Lee Ji-Eun Kim Hye-Jin Seo Jun-Hyeog Jang | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 1 |
| 8 | The protective mechanism of antioxidants in cadmium-induced ototoxicity in vitro and in vivo 显示文摘 | KIM Sujin JEONG Hyunja MYUNG Nohyil | 2008 | Environmental Health Perspect2008，116，： | 1 |
| 9 | An optimization model for natural gas supply portfolios of a power generation company显示文摘 | Panida Jirutitijaroen Sujin Kim Oran Kittithreerapronchai José Prina | 2013 | Applied Energy2013，，： | 1 |
| 10 | Sac-0601 prevents retinal vascular leakage in a mouse model of diabetic retinopathy显示文摘 | Sony Maharjan Sujin Lee Vijayendra Agrawal Hyun-Jung Choi Yong-Sun Maeng Kyeojin Kim Nam-Jung Kim Young-Ger Suh Young-Guen Kwon | 2011 | European Journal of Pharmacology2011，，1： | 1 |
| 11 | Differences in predictors of traditional and cyberbullying:a 2-year longitudinal study in Korean school children显示文摘 | YANG Sujin STEWART R KIM J M | 2013 | Child Adolesc Psychiatry2013，22，5： | 1 |
| 12 | SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence显示文摘Abstinence from prolonged psychostimulant use prompts stimulant withdrawal syndrome.Molecular adaptations within the dorsal striatum have been considered the main hallmark of stimulant abstinence. Here we explored striatal miRNA-target interaction and its impact on circulating miRNA marker as well as behavioral dysfunctions in methamphetamine(MA) abstinence. We conducted miRNA sequencing and profiling in the nonhuman primate model of MA abstinence, followed by miRNA qPCR,LC-MS/MS proteomics, immunoassays, and behavior tests in mice. In nonhuman primates, MA abstinence triggered a lasting upregulation of miR-137 in the dorsal striatum but a simultaneous downregulation of circulating miR-137. In mice, aberrant increase in striatal miR-137-dependent inhibition of SYNCRIP essentially mediated the MA abstinence-induced reduction of circulating miR-137. Pathway modeling through experimental deduction illustrated that the MA abstinence-mediated downregulation of circulating miR-137 was caused by reduction of SYNCRIP-dependent miRNA sorting into the exosomes in the dorsal striatum. Furthermore, diminished SYNCRIP in the dorsal striatum was necessary for MA abstinence-induced behavioral bias towards egocentric spatial learning. Taken together, our data revealed circulating miR-137 as a potential blood-based marker that could reflect MA abstinence-dependent changes in striatal miR-137/SYNCRIP axis, and striatal SYNCRIP as a potential therapeutic target for striatum-associated cognitive dysfunction by MA withdrawal syndrome. | Baeksun Kim Sung Hyun Tag Eunjoo Nam Suji Ham Sujin Ahn Juhwan Kim Doo-Wan Cho Sangjoon Lee Young-Su Yang Seung Eun Lee Yong Sik Kim Il-Joo Cho Kwang Pyo Kim Su-Cheol Han Heh-In Im | 2022 | Acta Pharmaceutica Sinica B2022，12，8： | 1 |
| 13 | Administration of growth factors for bone regeneration显示文摘 | Ye-Rang Yun Jun Hyeog Jang Eunyi Jeon Wonmo Kang Sujin Lee Jong-Eun Won Hae Won Kim Ivan Wall | 2012 | Regen Med2012，，3： | 1 |
| 14 | Fibroblast growth factor 2-functionalized collagen matrices for skeletal muscle tissue engineering显示文摘 | Ye-Rang Yun Sujin Lee Eunyi Jeon Wonmo Kang Kook-Hyun Kim Hae-Won Kim Jun-Hyeog Jang | 2012 | Biotechnology Letters2012，，4： | 1 |
| 15 | The time between paraquat ingestion and a negative dithioniteurine test in an independent risk factor for death and organ failure in acute paraquat intoxication显示文摘 | Sujin S Kim Y H Gil H W | 2012 | J Korean Med Sci2012，27，： | 1 |
| 16 | Complete Genome Sequence of Bacteriophage SSU5 Specific for Salmonella enterica serovar Typhimurium Rough Strains显示文摘 | Minsik Kim Sujin Kim Sangryeol Ryu | 2012 | Journal of Virology2012，，19： | 1 |
| 17 | Microstructural Investigation of Alloy 617 Creep-ruptured at High Temperature in a Helium Environment显示文摘A very high temperature reactor (VHTR) is one of the next-generation nuclear reactors chosen by the Generation IV International Forum.A Ni-base superalloy,Alloy 617,is considered as a primary candidate material for an intermediate heat exchanger(IHX)and hot gas duct (HGD) of the VHTR because of the superior creep resistance at a high temperature above 850 C.In this study,the microstructures of the specimens creepruptured at high temperatures in a helium environment were investigated.The decrease in rupture time was more pronounced with increasing creep temperature.In the specimens crept at 950 C,the external Cr-oxide layer of the specimens increased in thickness with increasing creep rupture time,and delaminated after a long-time creep.The high creep stress induced a deep penetration of carbide depletion along the grain boundaries at the early stage of the creep test.The creep temperature enhanced the growth rate of the decarburized zone depth clearly,but the temperature effect on the growth of the external oxide and internal oxide was not well understood as the surface reaction and creep stress affected the microstructures complexly. | Gyeong-Geun Lee Sujin Jung Jae-Young Park Woo-Gon Kim Sung-Deok Hong Yong-Wan Kim | 2013 | Journal of Materials Science & Technology2013，29，12： | 0 |
| 18 | 4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions显示文摘Many approaches to neurodegenerative diseases that focus on amyloid-βclearance and gene therapy have not been successful.Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases,including mitochondrial dysfunction.Plasma membrane(PM)redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction.Neurohormetic phytochemicals are known to induce the expression of detoxifying enzymes under stress conditions.In this study,mechanisms of neuroprotective effects of 4-hydroxycinnamic acid(HCA)were examined by analyzing cell survival,levels of abnormal proteins,and mitochondrial functions in two different neuronal cells.HCA protected two neuronal cells exhibited high expression of PM redox enzymes and the consequent increase in the NAD^(+)/NADH ratio.Cells cultured with HCA showed delayed apoptosis and decreased oxidative/nitrative damage accompanied by decreased ROS production in the mitochondria.HCA increased the mitochondrial complexes I and II activities and ATP production.Also,HCA increased mitochondrial fusion and decreased mitochondrial fission.Overall,HCA maintains redox homeostasis and energy metabolism under oxidative/metabolic stress conditions.These findings suggest that HCA could be a promising therapeutic approach for neurodegenerative diseases. | Sujin Park YoonA Kim Jaewang Lee Hyunsoo Seo Sang-Jip Nam Dong-Gyu Jo Dong-Hoon Hyun | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 19 | An insert in the Hpy region of hscp in Hefiothis virescens (Lepidoptera: Noctuidae) reveals a possible CORE-SINE of insects显示文摘抽象 A 新通常认为的 transposon 在烟草芽虫被识别, Heliothis virescens。这 transposon 作为一根完整的长度核心正弦被描绘(“核心”的 65 bp 特定的核苷酸突然散布了的核心元素) 那从三另外的 lepidopterans 和人类似于序列。特别地,这个序列的 A 盒子和 B 盒子区域最仔细从广泛地分叉的种类遵循了核心正弦的签名。这根核心正弦在基因 hscp 的一个亢奋的可变区域表现为多型性,它在神经轴突是 pyrethroid 杀虫药剂和另外的 xenobiotics 的目标。我们在 noctuid 蛾由于它的存在把这新通常认为的 transposon 描述了为 Noct-1。这是对有 A 盒子, B 盒子,目标地点复制,和从一只昆虫的候选人核心领域的一根全身的核心正弦的第一描述。 | Sujin Park Thomas M. Brown Sam-Kyu Kim Chunkeun Lim Jang Hyun Hur Yong Chul Park Saeyoull Cho | 2009 | Insect Science2009，16，3： | 0 |
| 20 | Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease:pathologic roles and therapeutic implications显示文摘Alzheimer's disease(AD)is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline.Failures in the development of therapeutics targeting amyloid-β(Aβ)and tau;principal proteins inducing pathology in AD,suggest a paradigm shift towards the development of new therapeutic targets.The gram-negative bacteria and lipopolysaccharides(LPS)are attractive new targets for AD treatment.Surprisingly,an altered distribution of gram-negative bacteria and their LPS has been reported in AD patients.Moreover,gram-negative bacteria and their LPS have been shown to affect a variety of AD-related pathologies,such as Aβ homeostasis,tau pathology,neuroinflammation,and neurodegeneration.Moreover,therapeutic approaches targeting gram-negative bacteria or gram-negative bacterial molecules have significantly alleviated AD-related pathology and cognitive dysfunction.Despite multiple evidence showing that the gram-negative bacteria and their LPS play a crucial role in AD pathogenesis,the pathogenic mechanisms of gram-negative bacteria and their LPS have not been clarified.Here,we summarize the roles and pathomechanisms of gram-negative bacteria and LPS in AD.Furthermore,we discuss the possibility of using gram-negative bacteria and gram-negative bacterial molecules as novel therapeutic targets and new pathological characteristics for AD. | Hyeon soo Kim Sujin Kim Soo Jung Shin Yong Ho Park Yunkwon Nam Chae won Kim Kang won Lee Sung-Min Kim In Duk Jung Hyun Duk Yang Yeong-Min Park Minho Moon | 2021 | Translational Neurodegeneration2021，10，4： | 0 |
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