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| 1 | CONVERGENCE OF CASCADE ALGORITHMS AND SMOOTHNESS OF REFINABLE DISTRIBUTIONS显示文摘In this paper, the author at first develops a method to study convergence of the cascadealgorithm in a Banach space without stable assumption on the initial (see Theorem 2.1), andthen applies the previous result on the convergence to characterizing compactly supportedrefinable distributions in fractional Sobolev spaces and Holder continuous spaces (see Theorems3.1, 3.3, and 3.4). Finally the author applies the above characterization to choosing appropriateinitial to guarantee the convergence of the cascade algorithm (see Theorem 4.2). | SUN QIYU Department of Mathematics, University of Houston, Houston, TX 77204, USA. Department of Mathematics, National University of Singapore, 10 Kent Ridge Crescent, 119260, Singapore. | 2003 | Chinese Annals of Mathematics,Series B2003，24，3： | 3 |
| 2 | CARMA3: A novel scaffold protein in regulation of NF-κB activation and diseases显示文摘CARD recruited membrane associated protein 3 (CARMA3) is a novel scaffold protein. It belongs to the CARMA protein family, and is known to activate nuclear factor (NF)- κB. However, it is still unknown which receptor functions upstream of CARMA3 to trigger NF-κB activation. Recently, several studies have demonstrated that CARMA3 serves as an indispensable adaptor protein in NF-κB signaling under some G protein-coupled receptors (GP- CRs), such as lysophosphatidic acid (LPA) receptor and angiotensin (Ang) Ⅱ receptor. Mechanistically, CARMA3 recruits its essential downstream molecules Bcl10 and MALT1 to form the CBM (CARMA3-Bcl10-MALT1) signalosome whereby it triggers NF-κB activation. GPCRs and NF-κB play pivotal roles in the regulation of various cellular functions, therefore, aberrant regulation of the GPCR/NF-κB signaling axis leads to the development of many types of diseases, such as cancer and atherogenesis. Recently, the GPCR/CARMA3/NF-κB signaling axis has been confirmed in these specific diseases and it plays crucial roles in the pathogenesis of disease progression. In ovarian cancer cell lines, knockdown of CARMA3 abolishes LPA receptor-induced NF-κB activation, and reduces LPA-induced ovarian cancer invasion. In vascular smooth cells, downregulation of CARMA3 substantially impairs Ang-Ⅱ-receptor-induced NF-κB activation, and in vivo studies have confirmed that Bcl10- deficient mice are protected from developing Ang-Ⅱ-receptor-induced atherosclerosis and aortic aneurysms. In this review, we summarize the biology of CARMA3, describe the role of the GPCR/CARMA3/NF-κB signaling axis in ovarian cancer and atherogenesis, and speculate about the potential roles of this signaling axis in other types of cancer and diseases. With a significant increase in the identification of LPA- and Ang-Ⅱ-like ligands, such as endothelin-1, which also activates NF-κB via CARMA3 and contributes to the development of many diseases, CARMA3 is emerging as a novel therapeutic target for various types of cancer and other diseases. | Jiyuan Sun, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, TX 77030, United States | 2010 | World Journal of Biological Chemistry2010，1，12： | 2 |
| 3 | Outsmarting cancer:an international brainstorm in Guangzhou显示文摘Cancer is the most deadly disease in the United States.In developing countries such as China, cancer is increasingly prevalent as a cause of death.The “war against cancer” that was initially declared in the United States has become a global war that requires an alliance of world-wide cancer researchers.As part of such an effort, the Second Guangzhou International Symposium on Oncology was held on May 20-22, 2011, in Guangzhou, China. | Chao-Nan Qian 1,2 and Wei Zhang 31 Laboratory of Cancer and Developmental Cell Biology,Van Andel Research Institute,Grand Rapids,MI 49503,USA 2 State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center,Guangzhou,Guangdong 510060,P.R.China 3 Department of Pathology,University of Texas MD Anderson Cancer Center,Huston,TX 77030,USA. | 2011 | Chinese Journal of Cancer2011，30，8： | 2 |
| 4 | Myelin activates FAK/Akt/NF-kappa B pathways and provokes CR3-dependent inflammatory response in murine system显示文摘 | Sun X Wang X Chen TX | 2010 | Plos One2010，5，2： | 1 |
| 5 | An ultrametastatic model of human coIon cancer in nude mice显示文摘 | Sun TX Sasson AR Jiang P | 1999 | Clin Exp Metastasis1999，17，1： | 1 |
| 6 | Myelin activates FAK/Akt/NF-kB pathways and provokes CR3-dependent inflammatory response in murine system显示文摘 | Sun X Wang X Chen TX | 2010 | PLoS ONE2010，5，2： | 1 |
| 7 | Remarks on the paper 显示文摘 | HAN ZL LI TX SUN S R etal | 2010 | Applied Mathematics and Computation2010，215，： | 1 |
| 8 | The study on regulation for the distribution of metastatic cervical lymph nodes of nasopharyngeal carcinoma 显示文摘 | Sun Y Lu TX Ma J | 2005 | Int J Radiation Oncology Biol Phys2005，63，2： | 1 |
| 9 | Conformational and functional differences between recombinant human lens alphaA-and alphaB-crystallin显示文摘 | Sun TX Das BK | 1997 | J Biol Chem1997，272，10： | 1 |
| 10 | Effects of oxide additives on sheet resistance of W thick film conductor显示文摘 | Liang TX Sun WZ Wang XH | 1996 | J Mater Sci1996，31，： | 1 |
| 11 | Conformational and functional differences between recombinant human lens alpha A- and alpha B-crystallin显示文摘 | Sun TX Das BK Liang JJ | 1997 | J Biol Chem1997，272，10： | 1 |
| 12 | Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking显示文摘 | Lu HA Sun TX Matsuzaki T | 2007 | J Biol Chem2007，282，28： | 1 |
| 13 | Identification of Biological Wort Turbidity Caused by Microbial Contamination of Gairdner Barley 显示文摘 | Zhang TX Xu P Sun J | 2009 | Joumal of the American Society of Brewing Chemists2009，67，1： | 1 |
| 14 | The synthesis and microstructure of morph-genetic TiC/C ceramics显示文摘 | Sun BH Fan TX Zhang D etal | 2004 | Carbon2004，42，： | 1 |
| 15 | Dynamics of the max-type difference equation Xn+1= max{1/Xn-m,An/Xn-1}显示文摘 | Sun TX Xi HJ Han CH | | 0，，1： | 1 |
| 16 | Intermolecular exchange and stabilization of recombinant human αA-and αB-Crystallin显示文摘 | Sun TX Liang JN | 1998 | J Biol Chem1998，273，： | 1 |
| 17 | Analyses of complication after ventriculoperitoneal shunt显示文摘 | Sun LZ Zhou J Shen TX | 2000 | J North Chin CoalMed2000，2，5： | 1 |
| 18 | The synthesis and microstructure of morph-genetic TiC/C ceramies显示文摘 | FAN TX ZHANG D OKABE T | 2004 | Carbon2004，42，： | 1 |
| 19 | An unwelcome guest in China: a pine - feeding mealybug 显示文摘 | Sun JH DeBarr GL Liu TX | 1996 | Journal of Forestry1996，，94： | 1 |
| 20 | Analyses of complication after ventriculoperitoneal shunt显示文摘 | Sun LZ Zhou J Shen TX | 2000 | J North Chin Coal Med2000，2，5： | 1 |
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