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| 1 | Hypoxla inducible factor 1 (HIF-1) and cardioprotection显示文摘 | Demet TEKIN Ali D DURSUN Lei XI | 2010 | Acta Pharmacologica Sinica2010，31，9： | 62 |
| 2 | The incidence of Mirizzi syndrome in patients undergoing endoscopic retrograde cholangiopancreatography显示文摘BACKGROUND:Mirizzi syndrome is a rare complication of cholelithiasis,characterized by the narrowing of the common hepatic duct as a result of mechanical compression and/or inflammation due to biliary calculus impacted in the infundibula of the gallbladder or in the cystic duct.In this study,we aimed to describe the clinical presentations,investigations,operative details,and complications of seven patients who underwent endoscopic retrograde cholangiopancreatography and were finally diagnosed with Mirizzi syndrome in our center. METHOD:We performed a retrospective analysis of the records of 7 patients with Mirizzi syndrome who underwent endoscopic retrograde cholangiopancreatography. RESULTS:The incidence of Mirizzi syndrome was 1.07% of 656 patients given endoscopic retrograde cholangiopan- creatography.Ultrasonography was able to diagnose one case.Endoscopic retrograde cholangiopancreatography suggested the diagnosis in five cases and helped further in the management of these patients.Four patients had cholecystectomy and T-tube placement,and two had cholecystectomy and choledochoduodenostomy.One patient with typeⅠMirizzi syndrome according to the Csendes classification successfully underwent laparoscopic cholecystectomy. CONCLUSIONS:In the study,the incidence of Mirizzi syndrome was 1.07%of patients who underwent endoscopic retrograde cholangiopancreatography. Preoperative diagnosis of Mirizzi syndrome by endoscopicretrograde cholangiopancreatography is important to prevent complications. | Nadir Yonetci Ufuk Kutluana Mustafa Yilmaz Ugur Sungurtekin Koray Tekin | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，5： | 30 |
| 3 | Cataract in diabetes mellitus显示文摘Diabetes mellitus (DM) is a chronic systemic disease that has increases in prevalence over time. DM can affect all ocular structures, with cataract being the most common ocular complication. Cataract is the leading cause of blindness worldwide. Due to several mechanisms, there is an increased incidence of cataract formation in the diabetic population. Advancements in technology have now made cataract surgery a common and safe procedure. However, the diabetic population is still at risk of vision-threatening complications, such as diabetic macular edema (ME), postoperative ME, diabetic retinopathy progression, and posterior capsular opacification. | Hasan Kiziltoprak Kemal Tekin Merve Inanc Yasin Sakir Goker | 2019 | World Journal of Diabetes2019，10，3： | 24 |
| 4 | Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis显示文摘瞄准:为了调查外长的 erythro-poietin (EPO ) 的效果,在钠 taurodeoxycholate- 的一个试验性的模型的尖锐的肺损害(ALI ) 上的管理导致了尖锐引起坏死胰腺炎(ANP ) 。方法:47 只男 Wistar 白鼠随机被划分成 7 个组:假冒的组(n = 5 ) , 3 个 ANP 组(n = 7 各个) 并且 3 个 EPO 组(n = 7 各个) 。ANP 被导致由后退进胆总管的 5% 钠 taurodeoxycholate 的注入。在 EPO 组的老鼠收到了 1000 U/kg 肌内的 EPO 立即在 ANP 的正式就职以后。在 ANP 组的老鼠相反被给 1 mL 生理盐水。所有动物被牺牲在手术后 24 h, 48 h 和 72 h。浆液 amilase, IL-2, IL-6 和肺织物 malondialdehyde (MDA ) 被测量。胸膜渗漏体积和肺 / 身体重量(LW/BW ) 比率是计算的。TNF-alpha, IL-2 和 IL-6 的织物层次组织化学地是屏蔽免疫。另外, ox-LDL 累积与免疫者荧光灯的染色被估计。在肺的组织病理学说的改变也被获得。结果:吝啬的胸膜渗漏体积,计算 LW/BW 比率,浆液 IL-6 和肺织物 MDA 层次比在 ANP 组在 EPO 组是显著地更低的。不,统计上,有效差量在这些组之中在浆液或 IL-2 的织物价值被观察。当时, ox-LDL 的肿瘤坏死 factor-alpha (TNF-alpha ) 和 IL-6 和累积的水平在 ANP 组的肺纸巾是明显的与 EPO 组相比,特别地在 72 h。组织病理学说的评估在外长的 EPO 管理以后在肺损害参数证实了改进,特别地在 48 h 和 72 h。结论:EPO 管理由禁止 polymorphonuclear (PMNL ) 在 ALI 参数导致重要减少累积,减少专业版的层次在每氧化的循环,保存微脉管的内皮房间正直和减少的氧化联系压力的类脂化合物的煽动性的 cytokines 并且因此,能在导致 ANP 的 ALI 被认为是一个 cytoprotective 代理人。 | Oge Tascilar Güldeniz Karadeniz Cakmak Ishak Ozel Tekin Ali Ugur Emre Bulent Hamdi Ucan Burak Bahadir Serefden Acikgoz Oktay Irkorucu Kemal Karakaya Hakan Balbaloglu Gürkan Kertis Handan Ankarali Mustafa Comert | 2007 | World Journal of Gastroenterology2007，13，46： | 8 |
| 5 | Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution显示文摘In this paper,an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing.The samples are illuminated by a nearly coherent illumination system,where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor.To increase the resolution,a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene,with small planar displacements.Displacements are resolved by a hybrid approach:(i)alignment of the LR images by a fast feature-based registration method,and(ii)fine adjustment of the sub-pixel information using a continuous optimization approach designed to find the global optimum solution.Numerical method for phase-retrieval is applied to decode the signal and reconstruct the morphological details of the analyzed sample.The presented approach was evaluated with various biological samples including sperm and platelets,whose dimensions are in the order of a few microns.The obtained results demonstrate a spatial resolution of 1.55 μm on a field-of-view of<30 mm^(2). | Antonio C Sobieranski Fatih Inci H Cumhur Tekin Mehmet Yuksekkaya Eros Comunello Daniel Cobra Aldo von Wangenheim Utkan Demirci | 2015 | Light(Science & Applications)2015，4，1： | 7 |
| 6 | New parameter in diagnosis of acute appendicitis:Platelet distribution width显示文摘AIM:To investigate the diagnostic accuracy of the mean platelet volume and platelet distribution width in acute appendicitis.METHODS:This retrospective,case-controlled study compared 295 patients with acute appendicitis(Group?Ⅰ),100 patients with other intra-abdominal infections(GroupⅡ),and 100 healthy individuals(GroupⅢ)between January 2012 and January 2013.The age,gender,and white blood cell count,neutrophil percentage,mean platelet volume,and platelet distribution width values from blood samples were compared among the groups.Statistical analyses were performed using SPSS for Windows 21.0 software.In addition,the sensitivity,specificity,positive and negative predictive values and likelihood ratios,and diagnostic accuracy were calculated.RESULTS:The mean ages of patients were 29.9±12.0years for Group?Ⅰ,31.5±14.0 years for GroupⅡ,and30.4±13.0 years for GroupⅢ.Demographic features such as age and gender were not significantly different among the groups.White blood cell count,neutrophil percentage and platelet distribution width were significantly higher in Group?Ⅰ?compared to groupsⅡandⅢ(P<0.05).Diagnostically,the sensitivity,specificity and diagnostic accuracy were 73.1%,94.0%,and 78%for white blood cell count,70.0%,96.0%,and 76.0%for neutrophil percentage,29.5%,49.0%,and 34.0%for mean platelet volume,and 97.1%,93.0%,and 96.0%for platelet distribution width,respectively.The highest diagnostic accuracy detected was for platelet distribution width between Group?Ⅰ?and GroupⅢ(P<0.01).CONCLUSION:Platelet distribution width analysis can be used for diagnosis of acute appendicitis without requiring additional tests,thus reducing the cost and loss of time. | Bulent Dinc Alten Oskay Selcan Enver Dinc Bilge Bas Sabri Tekin | 2015 | World Journal of Gastroenterology2015，21，6： | 5 |
| 7 | Laboratory evaluation in rheumatic diseases显示文摘Autoantibodies can help clinicians to allow early detection of autoimmune diseases and their clinical manifestations, to determine effective monitoring of prognosis and the treatment response. From this point, they have a high impact in rheumatic disease management. When usedcarefully they allow rapid diagnosis and appropriate treatment. However, as they may be present in healthy population they may cause confusion for interpreting the situation. False positive test results may lead to wrong treatment and unnecessary anxiety for patients. Autoantibody positivity alone does not make a diagnosis. Similarly, the absence of autoantibodies alone does not exclude diagnosis. The success of the test is closely related to sensitivity, specificity and likelihood ratios. So, interpretation of these is very important for a proper laboratory evaluation. In conclusion, in spite of the remarkable advances in science and technology, a deeply investigated anamnesis and comprehensive physical examination still continue to be the best diagnostic method. The most correct approach is that clinicians apply laboratory tests to confirm or exclude preliminary diagnosis based on anamnesis and physical examination. This review will discuss these issues. | Murat Birtane Sel?uk Yavuz Nurettin Ta?tekin | 2017 | World Journal of Methodology2017，7，1： | 3 |
| 8 | Three-to-one internal resonance in multiple stepped beam systems显示文摘In this study, the vibrations of multiple stepped beams with cubic nonlinearities are considered. A three-to-one internal resonance case is investigated for the system. A general approximate solution to the problem is found using the method of multiple scales (a perturbation technique). The modulation equations of the amplitudes and the phases are derived for two modes. These equations are utilized to determine steady state solutions and their stabilities. It is assumed that the external forcing frequency is close to the lower frequency. For the numeric part of the study, the three-to-one ratio in natural frequencies is investigated. These values are observed to be between the first and second natural frequencies in the cases of the clamped-clamped and clamped-pinned supports, and between the second and third natural frequencies in the case of the pinned-pinned support. Finally, a numeric algorithm is used to solve the three-to-one internal resonance. The first mode is externally excited for the clamped-clamped and clamped-pinned sup- ports, and the second mode is externally excited for the pinned-pinned support. Then, the amplitudes of the first and second modes are investigated when the first mode is externally excited. The amplitudes of the second and third modes are investigated when the second mode is externally excited. The force-response, damping-response, and frequencyresponse curves are plotted for the internal resonance modes of vibrations. The stability analysis is carried out for these plots. | A. Tekin E. zkaya S. M. Bagdatlh | 2009 | Applied Mathematics and Mechanics(English Edition)2009，30，9： | 3 |
| 9 | Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats显示文摘象 Glucagon 一样 peptide-2 (GLP-2 ) 有有势力反煽动性完成并且免于试验性的 ischemia/reperfusion (I/R ) 在肺、肠、心肌的织物的损害。然而,它对在肝的 I/R 损害的保护的能力是未知的。我们在老鼠在肝的 I/R 损害上调查了 GLP-2 预告的处理的潜在的角色。24 只老鼠的一个总数随机被划分成三个组(n = 8 ) 。第一个组是控制组;第二个组是对待车辆的肝的 ischemia/reperfusion (HIR,车辆盐对待) 组;并且第三个组是 GLP-2 pretreated I/R (GLP2 红外) 组。在第三个组的每只老鼠 intraperitoneally 被管理 5 ????? ???? 溜吗?? | Naci Topaloglu Adem Kucuk Sule Yildirm Mustafa Tekin Havva Erdem Mustafa Deniz | 2015 | Frontiers of Medicine2015，9，3： | 2 |
| 10 | Investigation of performance and emission characteristics of waste cooking oil as biodiesel in a diesel engine显示文摘Biodiesel is one of the most popular prospective alternative fuels and can be obtained from a variety of sources. Waste frying oil is one such source along with the various raw vegetable oils. However, some specific technical treatments are required to improve certain fuel properties such as viscosity and calorific value of the biodiesel being obtained from waste cooking oil methyl ester(WCOME). Various treatments are applied depending on the source and therefore the composition of the cooking oil. This research investigated the performance of WCOME as an alternative biofuel in a four-stroke direct injection diesel engine. An 8-mode test was undertaken with diesel fuel and five WCOME blends. The best compromise blend in terms of performance and emissions was identified. Results showed that energy utilization factors of the blends were similar within the range of the operational parameters(speed, load and WCOME content). Increasing biodiesel content produced slightly more smoke and NOx for a great majority of test points, while the CO and THC emissions were lower. | Yahya Ulusoy Rldvan Arslan Yucel Tekin Ali Surmen Alper Bolat Remzi Sahin | 2018 | Petroleum Science2018，15，2： | 2 |
| 11 | Behavioral symptoms in mild cognitive impairment显示文摘 | H. Feldman P. Scheltens E. Scarpini N. Hermann P. Mesenbrink L. Mancione S. Tekin R. Lane S. Ferris | 2004 | Neurology2004，，7： | 2 |
| 12 | Cost of illness among patients with diabetic foot ulcer in Turkey显示文摘AIM To evaluate the annual cost of patients with Wagner grade 3-4-5 diabetic foot ulcer(DFU) from the public payer's perspective in Turkey.METHODS This study was conducted focused on a time frame of one year from the public payer's perspective. Cost-ofillness(COI) methodology, which was developed by the World Health Organization, was used in the generation of cost data. By following a clinical path with the COI method, the main total expenses were reached by multiplying the number of uses of each expense item, the percentage of cases that used them and unit costs. Clinical guidelines and real data specific to Turkey were used in the calculation of the direct costs. Monte Carlo Simulation was used in the study as a sensitivity analysis.RESULTS The following were calculated in DFU treatment from the public payer's perspective: The annual average per patient outpatient costs $579.5(4.1%), imaging test costs $283.2(2.0%), laboratory test costs $284.8(2.0%), annual average per patient cost of intervention, rehabilitation and trainings $2291.7(16.0%), annual average per patient cost of drugs used $2545.8(17.8%)and annual average per patient cost of medical materials used in DFU treatment $735.0(5.1%). The average annual per patient cost for hospital admission is $7357.4(51.5%). The average per patient complication cost for DFU is $210.3(1.5%). The average annual per patient cost of DFU treatment in Turkey is $14287.70. As a result of the sensitivity analysis, the standard deviation of the analysis was $5706.60(n = 5000, mean = $14146.8, 95%CI: $13988.6-$14304.9). CONCLUSION The health expenses per person are $-PPP 1045 in 2014 in Turkey and the average annual per patient cost for DFU is 14-fold of said amount. The total health expense in 2014 in Turkey is $-PPP 80.3 billion and the total DFU cost has a 3% share in the total annual health expenses for Turkey. Hospital costs are the highest component in DFU disease costs. In order to prevent DFU, training of the patients at risk and raising consciousness in patients with diabetes mellitus(DM) will provide benefits in terms of economy. Appropriate and efficient treatment of DM is a health intervention that can prevent complications. | Ergun Oksuz Simten Malhan Bilge Sonmez Rukiye Numanoglu Tekin | 2016 | World Journal of Diabetes2016，7，18： | 2 |
| 13 | Frontal-subcortical neuronal circuits and clinical neuropsychiatry:an update显示文摘 | Tekin S Cummings JL | 2002 | J Psychosom Res2002，53，： | 1 |
| 14 | Energymanagement strategy for embedded fuel-cell systems using fuzzy logic显示文摘 | Tekin M Hissel D Pera M C | 2007 | IEEE Transactions on lndustrialElectronics2007，54，1： | 1 |
| 15 | Influence of proanthocyanidin on blunt traumatized lungs after nitrogen mustard exposure显示文摘 | YUCEL O SARGIN A K TEKINER A | 2009 | Gulhane Tip Dergisi2009，51，： | 1 |
| 16 | Periodontal healing after intentional auto--alloplastic reimplantation of injured immature upper front teeth 显示文摘 | Pohl Y Filippi A Tekin U | 2000 | J Clin Periodontol2000，27，3： | 1 |
| 17 | Apoptosis and necrosis in the circumventricular organs after experimental subarachnoid hemorrhage as detected with annexin V and caspase 3 immunostaining显示文摘 | Edebali N Tekin I O Acikgoz B | 2014 | Neurol Res2014，36，12： | 1 |
| 18 | Kineticis of the reduction of MnO2 with Fe^2+ ions in acidic solutions显示文摘 | Tekin T Bayramoglu M | 1993 | Hydrometallurgy1993，32，： | 1 |
| 19 | Use of Fenton oxidation to improve the biodegradability of a pharmaceutical wastewater显示文摘 | Huseyin Tekin Okan Bilkay Selale S Ataberk et ol | 2006 | Hazardous Materials2006，136，2： | 1 |
| 20 | De novo inverted tandem duplication of the short ann of chromosome 12 in a patient with microblepharon显示文摘 | Tekin M Jackson-Cook C Pandya A | 2001 | Am J Med Genet2001，104，1： | 1 |
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