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| 1 | Skin fold thickness at abdomen:a simple anthropometric measurement may compliment metabolic syndrome definition in patients with normal waist circumference显示文摘Backgroud and Objectives Previous studies have reported that skin fold thickness (SF) strongly correlated with insulin resistance in the metabolic syndrome (MetS). In this study, we developed a MetS definition by SF at A8 point (SFA8) on Erdheim diagram(MetSSFA8) in essential hypertensive patients. Subjects and Methods Medical records of 268 essential hypertensive patients (126males and 122 females) were analyzed, including 210 non-diabetic patients (NDM group) and 58 patients with diabetes (DM group).The mean age was 61.4 ± 9.9 and 59.0 ± 11.0 years, respectively. The control group consisted of 90 non-diabetic, non-hypertensive patients with a mean age of 58.0 ± 11.3 years. The proposed MetSSFA8 definition included SFA8 specific values ( ≥30 mm in female and ≥27 mm in male) and at least two of the following: raised triglyceride levels ( ≥1.7 mmol/L), or specific treatment for this lipid abnormality; raised blood pressure (SBP≥130 mmHg and/or DBP≥85 mmHg), or treatment of previously diagnosed hypertension;reduced HDL-cholesterol (< 1.03 mmol/L in men, <1.29 mmol/L in women), or specific treatment for this lipid abnormality; raised fasting plasma glucose (≥5.6 mmol/l), or previously diagnosed DM. Metabolic Syndrome by the National Cholesterol Education Program and International Diabetes Federation definitions were determined with abdominal obesity defined by Asia-Pacific criteria for waist circumference (NCEPA and IDFA). Results The percentage of MetS as defined by NCEPA, IDFA and MetSSFA8 in NDM group was lower than that of NCEPA, IDFA and MetSSFA8 in DM group [OR=7.7 (95%CI, 2.9-20.2) and 2.5 (95%CI, 1.4-4.8) and 2.7(95%CI, 1.3-5.6), respectively] and higher than that of the control group [OR=53.3 (95%CI, 16.7-170.6), 5.8 (95%CI, 2.6-13.2) and18.8 (95%CI, 7.3-48.7), respectively]. The percentage of MetS by NCEPA, IDFA and MetSSFA8 in males in NDM group was lower than the percentage of MetS by NCEPA, IDFA and MetSSFA8 in females in NDM group (50.8% and 77.9%, P< 0.001; 15,9% and 67.2%, P< 0.001; 60.3% and 73.8%, P <0.05, respectively). In subjects with normal WC or both normal WC and BMI, the percentage of MetS by SFAS was higher than that the percentage of MetS by NCEPA (36.9% and 50.8%, P< 0.05 and 36.0% and 51.0%, P< 0.05).The sensitivity, specificity, false positive rate, positive predictive value, negative predictive value of MetSSFA8 assessed with NCEPA definitions were 0.87, 0.73, 0.27, 0.79 and 0.82, respectively. There was a close agreement between MetSSFA8 and NCEPA (The coefficient of Kapa was 0.60, P< 0.001). Conclusions The MetSSFA8 definition was developed which may be useful in order to define and manage MetS in patients with normal WC or normal weight. | Toan C Nguyen Thai Q Ngo Son V Nguyen Hieu T Luong Khoa TA Pham Cong D Nguyen | 2006 | Journal of Geriatric Cardiology2006，3，2： | 2 |
| 2 | A 5-GHz direct-conversion CMOS transceiver显示文摘 | ZHANG P F THAI N Y LAM C | 2003 | IEEE J Sol Sta Circ2003，38，12： | 1 |
| 3 | Volatile anesthetics influence blood-brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury 显示文摘 | Thai SC Luh C Schaihle EV et~l | 2012 | PLoS One2012，7，50： | 1 |
| 4 | Realisation of grinding-hardening in workpieces of curved surfaces-partl: plunge cyclindrical grinding显示文摘 | Thai Nguyenl L C Zhang | 2011 | International Journal of Machine Tools & Man- ufacture2011，51，： | 1 |
| 5 | The effect of the degree of hydrolysis of the PVA and the plasticizer concentration on the color,opacity,and thermal and mechanical properties of films based on PVA and gelatin blends显示文摘 | Maria Thais M C Carvalho Rosemary A de Sobral Paulo J A | | 0，，02： | 1 |
| 6 | Analysis of laminated composite plates using higher-order shear deformation plate theory and node-based smoothed discrete shear gap method 显示文摘 | THAI C H TRAN L V TRAN D T NGUYEN-THOI T NGUYEN- XUAN H | 2012 | Applied Mathematical Modelling2012，36，11： | 1 |
| 7 | Pioglitazone reduces secondary brain damage afte~ experimental brain trauma by PPAR-~/-independent mechanisms显示文摘 | Thai S C I-leinetmnn M hth C | 2011 | J Neurotrauma2011，28，6： | 1 |
| 8 | Analysis of functionally graded plates by an efficient finite element method with node-based strain smoothing 显示文摘 | NGUYEN-XUAN H TRAN L V THAI C H NGUYEN-THOI T | 2012 | Thin-Walled Structures2012，54，： | 1 |
| 9 | The cavitation behavior with short length blades in centrifugal pump 显示文摘 | Thai Q Lee C | 2010 | Journal of Mechanical Science and Technology2010，24，10： | 1 |
| 10 | Physical-layer secret key generation with colluding untrusted relays 显示文摘 | THAI C D T LEE J QUEK T Q | 2016 | IEEE Transactions on Wireless Communications2016，15，2： | 1 |
| 11 | Tomato color changes under constant and variable storage temperatures: empirical models 显示文摘 | Thai C N Shewfelt F L Garner J C | 1990 | Transactions of the A SAE1990，33，2： | 1 |
| 12 | MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb 显示文摘 | Xiao C Calado DP Galler G Thai TH Patterson HC Wang J | 2007 | Cell2007，131，1： | 1 |
| 13 | The effect of the degree of hydrolysis of the PVA and the plasticizer con- centmtion on the color, opacity, and thermal and mechanical properties of films based on PVA and gelatin blends 显示文摘 | Maria Thais M C Carvalho Rosemary A de Sobral Paulo J A | 2008 | Journal of Food Engineering2008，87，2： | 1 |
| 14 | Molecular mechanisms by which saturated fatty acids modulate TNF-a expression in mouse macrophage lineage显示文摘 | De Lima-Salgado Thais Martins Alba-Loureiro Tatiana C Do Nascimento Caroline S | 2011 | Cell biochemistry and biophysics2011，59，2： | 1 |
| 15 | Zincfortification of whole rice grain through parboiling process 显示文摘 | Prom - u - thai C Rerkasem B Cakmak I | 2010 | Food Chemistry2010，120，3： | 1 |
| 16 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 17 | All optical discrete Fourier transform processor for 100 Gbit/s OFDM transmis- sion显示文摘 | Lee K Thai C Rhee J | 2008 | Optics Express2008，16，6： | 1 |
| 18 | An edge-based smoothed finite element method (ES-FEM) with stabi- lized discrete shear gap technique for analysis of Reiss- ner--Mindlin plates 显示文摘 | NGUYEN H X LIU G R THAI C H | 2010 | Computer Methods in Applied Mechanics and Engineering2010，，199： | 1 |
| 19 | Development and evaluation of a novel loop-mediate isothermal amplification method for rapid detection of severe acute respiratory syndrome coronavirus显示文摘 | Thai H Le M Vuong C | | 0，，： | 1 |
| 20 | Degradation profiles of east fihns of polyurethane and puly(m'ethane- urea) aqueous dispersions based on hydroxytermi- hated polybutadiene and different diisocyanates显示文摘 | FERNANDA M B COUTINHOA MARCIA C DELPECH THAIS L ALVES | 2003 | Polymer Degra- dation and Stability2003，81，1： | 1 |
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