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| 1 | Low dose oral curcumin is not effective in induction of remission in mild to moderate ulcerative colitis: Results from a randomized double blind placebo controlled trial显示文摘AIM To evaluate the role of oral curcumin in inducing clinical remission in patients with mild to moderate ulcerative colitis(UC).METHODS A prospective randomized double-blind placebo-controlled trial comparing the remission inducing effect of oral curcumin and mesalamine 2.4 g with placebo and mesalamine 2.4 g in patients of ulcerative colitis with mild to moderate severity was conducted from January 2003 to March 2005. The included patients received 1 capsule thrice a day of placebo or curcumin(150 mg) for 8 wk. Patients were evaluated clinically and endoscopically at 0,4 and 8 wk. The primary outcome was clinical remission at 8 wk and secondary outcomes were clinical response, mucosal healing and treatment failure at 8 wk. The primary analysis was intention to treat worst case scenario(ITT-WCS).RESULTS Of 300 patients with UC, 62 patients(curcumin: 29, placebo: 33) fulfilled the inclusion criteria and were randomized at baseline. Of these, 21 patients did not complete the trial, 41 patients(curcumin: 16, placebo: 25) finally completed 8 wk. There was no significant difference in rates of clinical remission(31.3% vs 27.3%, P = 0.75), clinical response(20.7% vs 36.4%, P = 0.18), mucosal healing(34.5% vs 30.3%, P = 0.72), and treatment failure(25% vs 18.5%, P = 0.59) between curcumin and placebo at 8 wk.CONCLUSION Low dose oral curcumin at a dose of 450 mg/d was ineffective in inducing remission in mild to moderate cases of UC. | Saurabh Kedia Vikram Bhatia Sandeep Thareja Sushil Garg Venigalla Pratap Mouli Sawan Bopanna Veena Tiwari Govind Makharia Vineet Ahuja | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，2： | 2 |
| 2 | Inflatable rock bolt bond strength versus rock mass rating (RMR): A comparative analysis of pull-out testing data from underground mines in Nevada显示文摘The purpose of this paper is to establish confidence in anticipated minimum bond strength for inflatable rock bolts by comparing the bond strength to variable geotechnical conditions using the rock mass rating(RMR) system. To investigate a correlation between these parameters,the minimum bond strength of pull-out tested inflatable rock bolts was compared to the RMR of the rock in which these bolts were placed. Bond strength vs. RMR plots indicate that expected minimum bond strength is positively correlated with RMR; however,the correlation is not strong. Cumulative percent graphs indicate that 97% of pull-out tests result in a minimum bond strength of 3.3 and 1.7 ton/m in RMR P 45 and <45,respectively.Although lower bond strengths are more commonly encountered in low RMR ground,high bond strengths are possible as well,yielding higher variability in bond strengths in low RMR ground. Bond strength of friction bolts relies on contact between the rock bolt and drill hole. Experience in Nevada indicates that RMR is known to affect both the quality and consistency of drill holes which likely affects bond strength. Drilling and bolting in low RMR ground is more sensitive to drilling and bolting practices,and strategies for maximizing bond strength in these conditions are discussed. | Barnard Chase Kallu Raj R. Warren Sean Thareja Rahul | 2016 | International Journal of Mining Science and Technology2016，26，1： | 2 |
| 3 | High n-type antimony dopant activation in germanium using laser annealing for n+/p junction diode显示文摘 | THAREJA G CHOPARA S ADAMS B | 2011 | IEEE Electron Device Letters2011，32，7： | 1 |
| 4 | High frequency of parasitic and viral stool pathogens in patients with active ulcerative colitis: Report from a tropical country显示文摘 | Debabrata Banerjee Rachana Deb Lalit Dar Bijay R. Mirdha Sunil K. Pati Sandeep Thareja Sushil Falodia Vineet Ahuja | 2009 | Scandinavian Journal of Gastroenterology2009，，3： | 1 |
| 5 | Electrical characteristics of germanium n+/p junctions obtained using rapid thermal annealing of coimplanted P and Sb显示文摘 | THAREJA G CHENG S KAMINS T | 2011 | IEEE Electron Device Letters2011，32，5： | 1 |
| 6 | Plume dynamics of laser - produced aluminum plasma in ambient nitrogen 显示文摘 | Sharma A K Thareja R K | 2005 | Applied Surface Science2005，243，： | 1 |
| 7 | Micronutrient antioxidant intake in patients with chronic pancreatitis 显示文摘 | Bhardwaj P Thareja S Prakash S | 2004 | Trop Gastroenterol2004，25，2： | 1 |
| 8 | Simulation of cluster formation in laser-ablated silicon plumes显示文摘 | Franklin S R Thareja R K | 2005 | Journal of Applied Physics2005，97，12： | 1 |
| 9 | An overview on 5alpha-reductase inhibitors显示文摘 | Aggarwal S Thareja S Verma A | 2010 | Steroids2010，75，2： | 1 |
| 10 | An overview on 5al-pha-reductase inhibitors显示文摘 | Aggarwal S Thareja S Verma A | 2010 | Steroids2010，75，2： | 1 |
| 11 | In vitro degradation of wheat straw by anaerobic fungi from small ruminants 显示文摘 | THAREJA A PUNIYA A K GOEL G | 2006 | Arch Anita Nutr2006，60，5： | 1 |
| 12 | An overview on 5α-reductase inhibitors显示文摘 | Saurabh Aggarwal Suresh Thareja Abhilasha Verma Tilak Raj Bhardwaj Manoj Kumar | 2009 | Steroids2009，，2： | 1 |
| 13 | An overview on 5alpha-reduuctase inhibitors 显示文摘 | Aggartwal S Thareja S Verma A | 2010 | Steroids2010，75，2： | 1 |
| 14 | Photoluminescence and ultraviolet laser emission from nanocrystalline ZnO thin films 显示文摘 | Mitra A Thareja R K | 2001 | J Appl Phys2001，89，4： | 1 |
| 15 | Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD) 显示文摘 | MADAN K BHARDWAI P THAREJA S | 2006 | J Clin Gastroenterol2006，40，10： | 1 |
| 16 | Comparatiw: redox status in alcoholic liver disease and nonalcoholic fatty liver disease 显示文摘 | Bhardwaj P Madan K Thareja S | 2008 | Hepatology International2008，2，2： | 1 |
| 17 | Protein tyrosine phosphatase 1B inhibitors: A molecular level legitimate ap- proach for the management of diabetes mellitus 显示文摘 | Thareja S Aggarwal S Bhardwaj T R | 2010 | Med Res Rev2010，，2： | 1 |
| 18 | 查看详情显示文摘 | Thareja P Velankar S | | 0，，03： | 1 |
| 19 | Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD) 显示文摘 | Madan K Bhardwaj P Thareja S | 2006 | J Clin Gastroenterol2006，40，10： | 1 |
| 20 | 显示文摘 | Mitra A Thareja R K Ganesan V | 2001 | Applied Surface Science2001，174，34： | 1 |
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