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| 1 | Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer显示文摘AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai JiaoTong University between October 2009 and October2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms,endoscopic findings and clinicopathological characteristics were evaluated retrospectively.RESULTS: There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage(P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23%were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses.Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography(CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients.CONCLUSION: Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis. | Hao Feng Ai-Guo Lu Xue-Wei Zhao Ding-Pei Han Jing-Kun Zhao Lei Shi Tobias S Schiergens Serene ML Lee Wen-Peng Zhang Wolfgang E Thasler | 2015 | World Journal of Gastroenterology2015，21，23： | 6 |
| 2 | Mstl and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yapl oncogene显示文摘 | Zhou D Conrad C Xia F Park JS Payer B Yin Y Lauwers GY Thasler W Lee JT Avruch J Bardeesy N | 2009 | Cancer Cell2009，16，5： | 1 |
| 3 | Impact of Perioperative Allogeneic Red Blood Cell Transfusion on Recurrence and Overall Survival After Resection of Colorectal Liver Metastases显示文摘 | Tobias S. Schiergens Markus Rentsch Michael S. Kasparek Katharina Frenes Karl-Walter Jauch Wolfgang E. Thasler | 2015 | Diseases of the Colon & Rectum2015，，1： | 1 |
| 4 | Present status and perspectives of cell-based therapies for liver diseases显示文摘 | Andreas Nussler Sarah Konig Michael Ott Etienne Sokal Bruno Christ Wolfgang Thasler Marc Brulport Geredn Gabelein Wiebke Schormann Maren Schulze Ewa Ellis Matthias Kraemer Frank Nocken Wolfgang Fleig Michael Manns Steven C. Strom Jan G. Hengstler | 2006 | Journal of Hepatology2006，，1： | 1 |
| 5 | Porcine hepatocytes for biohybrid artificial liver devices:a comparison of hypothemic storage techniques显示文摘 | PAHERNIK S A THASLER W E | 1996 | Artif Organs1996，20，11： | 1 |
| 6 | Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor,augmenter of liver regeneration显示文摘 | Thasler WE Dayoub R Muhlbauer M | 2006 | J Pharmacol Exp Ther2006，316，： | 1 |
| 7 | Acute pancreatitis:is there a need for surgery? 显示文摘 | Kleespies A Thasler WE SchMer C | 2008 | J Gastroenterol2008，46，8： | 1 |
| 8 | LPS- mediated NFkappaB activation varies between activated human hepatic stellate cells from different donors 显示文摘 | MUHLBAUER M WEISS TS THASLER WE | 2004 | Biochem Biophys Res Commun2004，325，1： | 1 |
| 9 | LPS-mediated Nfkappa B activation varies between activated human hepatic stel- late cells from different donors显示文摘 | Muhlbauer M Weiss TS Thasler WE | 2004 | Biochem Biophys Res Corn-mun2004，325，1： | 1 |
| 10 | Porcine hepatocytes for biohybrid artificial liver devices:a comparison of hypothemic storage technique显示文摘 | Koebe HG Pahernik SA Thasler WE | 1996 | Artifical Organ1996，20，11： | 1 |
| 11 | Effect of suture technique on the occurrence of incisional hernia after elective midline abdominal wall closure: study protocol for a randomized controlled trial显示文摘 | Fortelny RH Baumann P Thasler WE | 2015 | Trials2015，16，1： | 1 |
| 12 | Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro 显示文摘 | Sangspier M Dom C Thasler W E | 2012 | Experimental and Molecular Pathology2012，92，2： | 1 |
| 13 | Surgical options for inguinal hernia repair显示文摘 | Thasler WE | 2011 | MMW Fortschr Med2011，153，4950： | 1 |
| 14 | Insulin decreases inflammatory signal transcription factor expression in primary human liver cells after LPS challenge显示文摘 | Jeschke MG Klein D Thasler WE | 2008 | Mol Med2008，14，12： | 1 |
| 15 | Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor, augmenter of liver regeneration显示文摘 | Thasler W E Dayoub R Muhlbauer M | 2006 | J Pharmacol Exp Ther2006，316，2： | 1 |
| 16 | Hypothetmic storage of pig hepatocytes:influence of different storage solutions and cell density显示文摘 | Pahernik SA Thasler WE Muelle-Hoecker J | 1996 | Cryobiology1996，33，： | 1 |
| 17 | Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma显示文摘 | Thasler WE Schlott T Thelen P | 2005 | Histopathology2005，47，1： | 1 |
| 18 | A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease显示文摘 | Marcus Mühlbauer Anja K Bosserhoff Arndt Hartmann Wolfgang E Thasler Thomas S Weiss Hans Herfarth Guntram Lock Jürgen Sch?lmerich Claus Hellerbrand | 2003 | Gastroenterology2003，，4： | 1 |
| 19 | A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease显示文摘 | Marcus Mühlbauer Anja K Bosserhoff Arndt Hartmann Wolfgang E Thasler Thomas S Weiss Hans Herfarth Guntram Lock Jürgen Sch?lmerich Claus Hellerbrand | 2003 | Gastroenterology2003，，4： | 1 |
| 20 | Porcine hepatocytes for biohybrid artificial liver devices:a comparison of hypothermic storage techniques显示文摘 | Koebe HG Pahernik SA Thasler WE | 1996 | Artif Organs1996，20，11： | 1 |
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