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116篇 您的检索式:作者名="Thomas KE"
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1Variations in carbon isotopic composition in the subcontinental lithospheric mantle beneath the Yangtze and North China Cratons:Evidence from in-situ analysis of diamonds using SIMS显示文摘The components and evolution of subcontinental lithospheric mantle beneath the North China Craton and the Yangtze Craton is a current topic in the geological study of China and the carbon isotopic composition of diamond is one of the most direct probes into cratonic lithospheric mantle processes.In this paper,in-situ SIMS(Secondary Ion Mass Spectrometry) techniques were used to analyze the carbon isotope compositions at different internal growth zones of diamonds from Shandong and Liaoning in the North China Craton and Hunan in the Yangtze Craton.It was found that the carbon isotopic range of diamonds from the North China Craton are rather distinct from those of the Yangtze Craton;the former has a range of 6.0‰ to 2.0‰(relative to VPDB) with an average value of 3.0‰ in their core areas,which is consistent with global peridotitic diamonds;the diamonds from the Yangtze Craton,however,have a carbon isotopic range from 8.6‰ to 3.0‰ with an average value of 7.4‰ in their core areas,being more consistent with global eclogitic diamonds.The variations of carbon isotope ratios between different internal growth zones in individual diamonds were different in the three diamond localities studied.There was a clear correlation between changes in carbon isotopic composition and phases of diamond dissolution and new growth,while no correlation was observed between δ13C and internal inclusions.The variations suggest that the carbon isotopic compositions of mantle fluids were changing during the process of diamond crystallization,and that the heterogeneity of the carbon isotopic composition in mantle carbon reservoirs was a more important factor than carbon isotope fractionation in controlling the carbon isotopic compositions and their variation in diamonds.In addition,the preliminary results of in-situ nitrogen analyses demonstrated that the variation of carbon isotopic compositions between the core and outer growth zones does not correlate with nitrogen abundances,implying either that diamonds crystallized in an open environment or that the carbon isotopic composition and nitrogen contents in mantle fluids were controlled by other,not yet understood factors.The experimental results provide hints that the isotopic composition of carbon and its original sources were different in metasomatic fluids controlling diamond formation in the mantle beneath the North China Craton and the Yangtze Craton.CHEN Hua QIU ZhiLi LU TaiJin STERN Richard STACHEL Thomas SUN Yuan ZHANG Jian KE Jie PENG ShuYi QIN SheCai 2013Chinese Science Bulletin2013,58,1:7
2Evolutionary Optimization: Pitfalls and Booby Traps显示文摘Evolutionary computation (EC), a collective name for a range of metaheuristic black-box optimization algorithms, is one of the fastest-growing areas in computer science. Many manuals and 'how-to's on the use of different EC methods as well as a variety of free or commercial software libraries are widely available nowadays. However, when one of these methods is applied to a real-world task, there can be many pitfalls and booby traps lurking - certain aspects of the optimization problem that may lead to unsatisfactory results even if the algorithm appears to be correctly implemented and executed. These include the convergence issues, ruggedness, deceptiveness, and neutrality in the fitness landscape, epistasis, non-separability, noise leading to the need for robustness, as well as dimensionality and scalability issues, among others. In this article, we systematically discuss these related hindrances and present some possible remedies. The goal is to equip practitioners and researchers alike with a clear picture and understanding of what kind of problems can render EC applications unsuccessful and how to avoid them from the start.Thomas Weise Raymond Chiong Ke Tang 2012Journal of Computer Science & Technology2012,27,5:5
3Nanoscale inhibition of polymorphic and ambidextrous lAPP amyloid aggregation with small molecules显示文摘Aleksandr Kakinen Jozef Adamcik Bo Wang Xinwei Ge Raffaele Mezzenga Thomas P. Davis Feng Ding Pu Chun Ke 2018Nano Research2018,11,7:4
4Wafer-scale MOCVD growth of monolayer M0S2 on sapphire and SiO2显示文摘High-quality and large-scale growth of monolayer molybdenum disulfide(MoS2)has caught intensive attention because of its potential in many applications due to unique electronic properties.Here,we report the wafer-scale growth of high-quality mono layer MoS2 on singlecrystalline sapphire and also on SiO2 substrates by a facile metal-organic chemical vapor deposit!on(MOCVD)method.Prior to growth,an aqueous solution of sodium molybdate(Na2MoO4)is spun onto the substrates as the molybdenum precursor and diethyl sulfide((C2H5)2S)is used as the sulfur precursor duri ng the growth.The grown MoS2 films exhibit crystal I i nity,good electrical performa nee(electro n mobility of 22 cm2·V^-1·s^-1)and structural continuity maintained over the entire wafer.The sapphire substrates are reusable for subsequent growth.The same method is applied for the synthesis of tungsten disulfide(WS2).Our work provides a facile,reproducible and cost-efficient method for the scalable fabricati on of high-quality mono layer MoS2 for versatile applicati ons,such as electro nic and optoelectr onic devices as well as the membranes for desalination and power generation.Huanyao Cun Michal Macha HoKwon Kim Ke Liu Yanfei Zhao Thomas LaGrange Andras Kis Aleksa ndra Radeno vic 2019Nano Research2019,12,10:3
5DNA barcoding of East Asian Amentotaxus (Taxaceae): Potential new species and implications for conservation显示文摘DNA barcoding 是为用标准化 genomic DNA 碎片的种类鉴定的一个有用工具。类 Amentotaxus,由五或六种组成,被限制到华南,东北印度,老挝,和越南。所有种类是被估计了全球性或全国地威胁了。然而,关于包含的种类的数字有无常,特别在南部的中国,北越南,和老挝的边阶区域。我们选择了五 DNA barcodes (rbcL, matK, trnH-psbA, trnL-F,和内部抄录分隔符(它的)) 在这个类评估他们的辨别能力,并且调查 Amentotaxus 的当前的分类。我们的结果显示所有选择 barcoding 区域为 PCR 显示出普遍性的高水平并且定序。当六种被认出时,原子 ribosomal DNA 区域它叶绿体 DNA 区域 trnL-F 在他们的自己上使用了的 and 提供了最高的鉴定成功(60%) 。也包括了它的 or trnL-F 的二 barcode 联合有一样的种类辨别能力。用另外的 barcodes 的联合没改进种类鉴定成功。五种什么时候仅仅被认出,与 A。hatuyenensis T. H。当作 A 的一个同义词的 Nguyen。yunnanensis H.L. 李,辨别率升起到 100% 。我们的结果也显示从云南省,中国,老挝人的蔡省,越南,和老挝的最近的集合可以代表潜在的新种。从这研究的调查结果将为为在公民和 trans 边界区域的威胁的 Amentotaxus 种类的适当保存策略的明确的表达是很有用的。Lian-Ming Gao Yan Li Loc Ke Phan Li-Jun Yan Philip Thomas Long Ke Phan Michael Mbller De-Zhu Li 2017Journal of Systematics and Evolution2017,55,1:2
6Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier显示文摘Nicola F. Fletcher Garrick K. Wilson Jacinta Murray Ke Hu Andrew Lewis Gary M. Reynolds Zania Stamataki Luke W. Meredith Ian A. Rowe Guangxiang Luo Miguel A. Lopez–Ramirez Thomas F. Baumert Babette Weksler Pierre–Olivier Couraud Kwang Sik Kim Ignacio A. R 2012Gastroenterology2012,,3:2
7Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds.Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan 2017Science China(Physics,Mechanics & Astronomy)2017,60,6:2
8Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide显示文摘The amyloid aggregation of peptides and proteins is a hallmark of neurological disorders and type 2 diabetes.Human islet amyloid polypeptide(IAPP),co-secreted with insulin by pancreaticβ-cells,plays dual roles in both glycemic control and the pathology of type 2 diabetes.While IAPP can activate the NLRP3 inflammasome and modulate cellular autophagy,apoptosis and extracellular matrix metabolism,no data is available concerning intracellular protein expression upon exposure to the polypeptide.More surprisingly,how intracellular protein expression is modulated by nanoparticle inhibitors of protein aggregation remains entirely unknown.In this study,we first examined the changing proteomes ofβTC6,a pancreaticβ-cell line,upon exposure to monomeric,oligomeric and fibrillar IAPP,and detailed cellular protein expression rescued by graphene quantum dots(GQDs),an IAPP inhibitor.We found that 29 proteins were significantly dysregulated by the IAPP species,while majority of these proteins were nucleotide-binding proteins.Collectively,our liquid chromatography tandem-mass spectrometry,fluorescence quenching,helium ion microscopy,cytotoxicity and discreet molecular dynamics simulations data revealed a remarkable capacity of GQDs in regulating aberrant protein expression through H-bonding and hydrophobic interactions,pointing to nanomedicine as a new frontier against human amyloid diseases.Ava Faridi Yunxiang Sun Monika Mortimer Ritchlynn R.Aranha Aparna Nandakumar Yuhuan Li Ibrahim Javed Aleksandr Kakinen Qingqing Fan Anthony W.Purcell Thomas P.Davis Feng Ding Pouya Faridi Pu Chun Ke 2019Nano Research2019,12,11:2
9Utility of left subclavian artery revascularization in association with endoluminal repair of acute and chronic thoracic aortic pathology显示文摘Brain GP Mark KE Thomas GG 2006J Vase Surg2006,43,:1
10Incidence of traumatic brain injury in the United States, 2003显示文摘Rutland--Brown W Langlois JA Thomas KE 2006J Head Trauma Rehabil2006,21,:1
11Optical performance monitoring using artificial neural network trained with asynchronous amplitude histograms 显示文摘Thomas Shun Rong Shen Ke Meng Alan Pak Tao Lau 20101EEE Photonics Technology Letters2010,22,22:1
12Age- specific effective doses for pediatric MSCT examinations at a large children's hospital using DLP conversion coefficients: a simple estimation method显示文摘Thomas KE Wang B 2008Pediatr Radiol2008,38,6:1
13Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn’s disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis显示文摘Julia Seiderer Fabian Schnitzler Stephan Brand Tanja Staudinger Simone Pfennig Karin Herrmann Katrin Hofbauer Julia Dambacher Cornelia Tillack Michael Sackmann Burkhard G?ke Peter Lohse Thomas Ochsenkühn 2006Scandinavian Journal of Gastroenterology2006,,12:1
14Scapular dyskine- sis is detrimental to shoulder tendon properties and joint me- chanics in a rat model显示文摘Reuther KE Thomas S J Tucker J J 2014J Orthop Res2014,32,11:1
15Reciprocal interaction of human immu- nodefieieney virus and hepatitis C virus infections显示文摘Nelson KE Thomas DL 2001Clin Diagn Lab Immunol2001,8,5:1
16Induction of early inflammatory gene expression in a murine model of nonresuscitated,fixed-volume hemorrhage显示文摘Rajnik M Salkowski CA Thomas KE 2002Shock2002,17,4:1
17Effect of return to overuse activity following an isolated supraspinatus tendon tear on adjacent intact tendons and glenoid cartilage in a rat model显示文摘Reuther KE Thomas SJ Sarver JJ 2013J Orthop Res2013,31,5:1
18Chronic haloperidol treatment results in a decrease in the expression of myelin/olgodendrocyte-related genes in the mouse brain显示文摘Narrayan S Kass KE Thomas EA 0,,04:1
19BK virus in the kidney transplant patient显示文摘Kuppachi S Thomas B Kokko KE 2013Am J Med Sci2013,345,6:1
20Virtual reality forstroke rehabilitation 显示文摘Laver KE George S Thomas S et M 2011Cochrane Database Syst Rev2011,,00:1
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