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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | The temporal price relationship between S&P 500 futures prices and the S&P 500 index显示文摘 | Kawaller Ira G Paul D Koch Timothy W Koch | 1987 | Journal of Finance1987，5，： | 2 |
| 3 | Development and potential role of type-2 sodium-glucose transporter inhibitors for management of type 2 diabetes 显示文摘 | Timothy C H Simon W D | 2011 | Diabetes Ther2011，2，3： | 1 |
| 4 | Evolving space-filling curves to distribute radial basis functions over an inputspace显示文摘 | Timothy D C | 1994 | IEEE Transactions on Neural Networks1994，5，： | 1 |
| 5 | Evolving space filling curves to distribute radial basis functions over an in- put space 显示文摘 | Bruce A W Timothy D C | 1994 | IEEE Transactions on Neural Net- works1994，，5： | 1 |
| 6 | Transparent conducting Nnc oxide thin films doped with aluminum and molybdenum显示文摘 | JOEL N D TIMOTHY A G DAVID M W TERESA M B MATTHEW Y BOBBY T TIMOTHY J C | 2007 | Journal V-acuum Society Technology2007，25，4： | 1 |
| 7 | A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome显示文摘 | Mark E Curran Igor Splawski Katherine W Timothy G.Michael Vincen Eric D Green Mark T Keating | 1995 | Cell1995，，： | 1 |
| 8 | A hierarchical factor analysis of a safety culture survey显示文摘 | Christopher B F Timothy D L Brian W | 2013 | Journal ofSafety Research2013，45，2： | 1 |
| 9 | Holmium:YAG laser lithotripsy for upper urinary tract calculi in 598 patients显示文摘 | James D W Timothy A W | 2002 | J Urol2002，167，： | 1 |
| 10 | Neurobehavioral effects of dietary soy phytoestrogens显示文摘 | Edwin D Lephart Timothy W | 2002 | Neurotoxicology and Teratology2002，24，： | 1 |
| 11 | Constitutive modeling of aluminum nitride for large strain, high-strain rate, and high-pressure applications显示文摘 | Timothy J Holmquist Douglas W Templeton Krishan D Bishnoi | 2001 | International Journal of Impact Engineering2001，，3： | 1 |
| 12 | A Model of Dual Attitudes 显示文摘 | Timothy D W Sammel L etal | 2000 | Psychology Review2000，107，： | 1 |
| 13 | Efficacy of difloxacin in calves experimentally infected with Mannheimia haemolytica显示文摘 | Timothy W J Olchowy D V M phD | 2000 | American Journal of Veterinary Research2000，61，6： | 1 |
| 14 | Cross -boder shopping:A North American perspective显示文摘 | Timothy D J Butler R W | | 0，，01： | 1 |
| 15 | Hippocampal mineralocorticoid, but not glucocorticoid, receptors modulate anxietylike behavior in rats 显示文摘 | Smythe J W Murphy D Timothy C | 1997 | Pharmacol Biochem Behav1997，56，3： | 1 |
| 16 | Heme and iron metabolism: Role in cerebral hemorrhage显示文摘 | KENNETH R W FRANK R S TIMOTHY D A | 2003 | Cerebral Blood Flow & Metabolism2003，23，： | 1 |
| 17 | Dielectric properties of foodsrelevant to RF and microwave pasteurization and sterilization显示文摘 | Yifen Wang Timothy D W | | 0，，03： | 1 |
| 18 | A Model of Dual Attitudes显示文摘 | TIMOTHY D W SAMMELL | 2000 | Psychology Review2000，107，1： | 1 |
| 19 | Effects of participation in a martial arts-based antibullying program in elementary schools 显示文摘 | Stuart W T Bridget K B Timothy D N Eric M V Peter F Stephen W T | 2008 | Psychology in the School2008，45，10： | 1 |
| 20 | Vector field path following for small unmanned air vehicles 显示文摘 | NELSON Derek R BARBER D Blake MCLAIN Timothy W | 2007 | IEEE Transactions on Robotics2007，23，3： | 1 |
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