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| 1 | Preparation and visible photocatalytic dye degradation of Mn-TiO2/sepiolite photocatalysts显示文摘The performance of Mn-TiO2/sepiolite photocatalysts prepared by the solgel method and calcinated at different temperatures was studied in the photocatalytic degradation of direct fast emerald green dye under visible light irradiation,and a series of analytical techniques such as XRD,SEM,FTIR,TG-DSC,XPS,UV-vis-DRS and Raman spectroscopy were used to characterize the morphology,structure and optical properties of the photocatalysts.It is found that the anatase TiO2 was formed in all photocatalysts.Mn4+might incorporate into the lattice structure of TiO2 and partially replace Ti4+,thus causing the defects in the crystal structure and the broadening of the spectral response range of TiO2.At the same time,TiO2 particles were dispersed on the surface of the sepiolite,which immobilized TiO2 particles with sepiolite via the bond of Ti-O-Si.Mn-TiO2/sepiolite calcined at 400°C exhibits the highest photocatalytic activity and the degradation rate of direct fast emerald green is up to 98.13%.Meanwhile,it also shows good stability and universality. | Pengfei Zhu Zhihao Ren Ruoxu Wang Ming Duan Lisi Xie Jing Xu Yujing Tian | 2020 | Frontiers of Materials Science2020，14，1： | 6 |
| 2 | Verification of Bacteroidales 16S rRNA markers as a complementary tool for detecting swine fecal pollution in the Yangtze Delta显示文摘To correctly assess and properly manage the public health risks associated with exposure to contaminated water,it is necessary to identify the source of fecal pollution in a watershed.In this study,we evaluated the efficacy of our two previously developed real time-quantitative PCR(qPCR)assays for the detection of swine-associated Bacteroidales genetic markers(gene 1-38,gene 3-53)in the Yangtze Delta watershed of southeastern China.The results indicated that the gene 1-38 and 3-53 markers exhibited high accuracy(92.5%,91.7%conditional probability,respectively)in detecting Bacteroidales spp.in water samples.According to binary logistic regression(BLR),these two swine-associated markers were well correlated(P<0.05)with fecal indicators(Escherichia coli and Enterococci spp.)and zoonotic pathogens(E.coli O157:H7,Salmonella spp.and Campylobacter spp.)in water samples.In contrast,concentrations of conventional fecal indicator bacteria(FIB)were not correlated with zoonotic pathogens,suggesting that they are noneffective at detecting fecal pollution events.Collectively,the results obtained in this study demonstrated that a swinetargeted qPCR assay based on two Bacteroidales genes markers(gene 1-38,gene 3-53)could be a useful tool in determining the swine-associated impacts of fecal contamination in a watershed. | Lihua Fan Xiaofeng Zhang Ruoxue Zeng Suhua Wang Chenchen Jin Yongqiang He Jiangbing Shuai | 2020 | Journal of Environmental Sciences2020，32，4： | 1 |
| 3 | Carbohydrate-based drugs launched during 2000-2021显示文摘Carbohydrates are fundamental molecules involved in nearly all aspects of lives,such as being involved in formating the genetic and energy materials,supporting the structure of organisms,constituting invasion and host defense systems,and forming antibiotics secondary metabolites.The naturally occurring carbohydrates and their derivatives have been extensively studied as therapeutic agents for the treatment of various diseases.During 2000 to 2021,totally 54 carbohydrate-based drugs which contain carbohydrate moities as the major structural units have been approved as drugs or diagnostic agents.Here we provide a comprehensive review on the chemical structures,activities,and clinical trial results of these carbohydrate-based drugs,which are categorized by their indications into antiviral drugs,antibacterial/antiparasitic drugs,anticancer drugs,antidiabetics drugs,cardiovascular drugs,nervous system drugs,and other agents. | Xin Cao Xiaojing Du Heng Jiao Quanlin An Ruoxue Chen Pengfei Fang Jing Wang Biao Yu | 2022 | Acta Pharmaceutica Sinica B2022，12，10： | 1 |
| 4 | 淋巴细胞密度及分布与直肠癌新辅助治疗反应的关系显示文摘背景:研究认为,淋巴细胞密度与直肠癌预后相关;但新辅助治疗前淋巴细胞分布模式对预后的影响尚不清楚。本研究旨在评估淋巴细胞的分布及密度与直肠癌新辅助治疗反应的关系。方法:对前瞻性队列中接受新辅助治疗的134例直肠癌患者进行回顾性分析。对新辅助治疗前活检标本进行免疫组化染色(CD4和CD8)。评估瘤内腺体周围淋巴细胞(IPL)和肿瘤浸润淋巴细胞(TIL)的密度。采用logistic回归模型(包括临床病理特征、分子特征及治疗方案)评估不同淋巴细胞的密度与肿瘤退缩分级(TRG)的关系。结果:CD8^(+)TIL密度高的患者接受新辅助治疗后获得了更佳的TRG(OR=0.23,95%CI:0.07-0.76,P<0.001)。而CD8^(+)IPL(P=0.033)、CD4^(+)IPL(P=0.156)和CD4^(+)TIL(P=0.170)则与TRG无明显相关性。敏感性分析未发现CD8^(+)TIL与新辅助放疗(P_(相互作用)=0.831)或化疗(P_(交互作用)=0.879)对TRG的影响存在交互作用。结论:本研究结果显示,CD8^(+)TIL而不是CD8^(+)IPL,可独立影响直肠癌新辅助治疗反应,这种影响不受放疗或化疗方案的干扰。 | Sicong Lai Xiaoying Lou Xinjuan Fan Weipeng Sun Yanhong Deng Jianping Wang Yan Huang Ruoxu Dou | 2020 | Gastroenterology Report2020，8，6： | 1 |
| 5 | 6-4 Development of a Slow Tuner for the 162.5 MHz Superconducting Half-wave Resonator in IMP显示文摘China-ADS project, a continuous wave (CW) proton accelerator and aims to design and build an ADS demonstration facility has been proposed and launched actively in China. HWR ( =0.10) superconducting cavity with frequency of 162.5 MHz is applied to one of the parallel injectors prompted by Institute of Modern Physics (IMP)[1]. | Liu Lubei Zhang Bin He Yuan Zhang Shenghu Wang Ruoxu | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 6 | 6-7 Dual-windows Coupler R&D in IMP显示文摘IMP hosts the project of high intensity Heavy Ion Accelerator Facility (HIAF). High power input couplers are needed for the SRF cavities. In order to assemble cryo-module easily and run the machine safely, new TTF-III like demountable dual-ceramic coupler is developed. This paper will present some results of the 162.5 MHz coupler for the tapper HWR cavity. | Li Yongming Wang Ruoxu Zhang Shenghu Jiang Tiancai Sun Guozhen Liu Lubei He Yuan Zhao Hongwei | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 7 | 直肠癌指南对比:例外反证规则?显示文摘临床实践指南正在全球范围内推动着早期或局部进展期直肠癌的治疗规范,但不同指南间的巨大差异也造成了认识上的混乱。我们比较了5个来自专业协会/机构的最新临床实践指南:美国国立综合癌症网络(NCCN)、美国结直肠外科医师学会(ASCRS)、欧洲肿瘤内科学会(ESMO)、中国国家卫生健康委员会(NHC)及中国临床肿瘤学会(CSCO)。本文对一些造成差异的关键证据进行了梳理,以帮助读者更好地理解一些看似矛盾的指南推荐。 | Ruoxu Dou Siqi He Yanhong Deng Jianping Wang | 2021 | Gastroenterology Report2021，9，4： | 0 |
| 8 | Mutation inε-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice显示文摘Myoclonus dystonia syndrome(MDS)is an inherited movement disorder,and most MDS-related mutations have so far been found in theε-sarcoglycan(SGCE)coding gene.By generating SGCE-knockout(KO)and human 237 C>T mutation knock-in(KI)mice,we showed here that both KO and KI mice exerted typical movement defects similar to those of MDS patients.SGCE promoted filopodia development in vitro and inhibited excitatory synapse formation both in vivo and in vitro.Loss of function of SGCE leading to excessive excitatory synapses that may ultimately contribute to MDS pathology.Indeed,using a zebrafish MDS model,we found that among 1700 screened chemical compounds,Vigabatrin was the most potent in readily reversing MDS symptoms of mouse disease models.Our study strengthens the notion that mutations of SGCE lead to MDS and most likely,SGCE functions to brake synaptogenesis in the CNS. | Jiao Li Yiqiong Liu Qin Li Xiaolin Huang Dingxi Zhou Hanjian Xu Feng Zhao Xiaoxiao Mi Ruoxu Wang Fan Jia Fuqiang Xu Jing Yang Dong Liu Xuliang Deng Yan Zhang | 2021 | Neuroscience Bulletin2021，37，3： | 0 |
| 9 | 耦合器测试系统的改进显示文摘The 162.5 MHz HWR010 and HWR015 superconducting cavities have been used in the Chinese ADS 25 MeV demo SRF Linac.Each cavity is feed with RF power by one high power coupler.The maximum design coupler power is 20 kW in traveling mode.Prior to assembly,couplers need to be tested and conditioned at room temperature.And the characteristics of conditioning phenomenon can also be thoroughly studied during the conditioning process.Figure 1 presents the block diagram of the test stand system.However,the previous test system is ineligible because of its sundry problems lying in its LLRF control system and its test stand.To overcome the defects of the previous test system,a series of improvements were performed. | Jiang Tiancai Chen Long Wang Ruoxu Li Chunlong | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
| 10 | Development of RF Cavities at the Department of RF Cavity in 2019显示文摘The cavity design including RF design and multi-physics analysis of the RFQ for the CAFe(Chinese Accelerator Facility for super-heavy Elements)project have been completed by the end of 2019. | Zhang Zhouli Yue Weiming Li Chenxing Li Chunlong Huang Yulu Wang Ruoxu Xu Xianbo Zhang Shengxue Zhang Shenghu He Tao Yang Lei Xing Chaochao Lin Zeqiang | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 11 | 650 MHz Elliptical Cavities Development in IMP for CiADS显示文摘Multicell superconducting radio frequency(SRF)elliptical cavities are proposed for efficient acceleration of proton beam in the Chinese initiative Accelerator Driven Subcritical System(CiADS). | Huang Yulu Wang Ruoxu Liu Lubei Jiang Tiancai Zhang Shengxue Liu Shuhui Tan Teng Guo Hao Li Chunlong Yue Weiming Zhang Zhouli Wang Zhijun Zhang Shenghu He Yuan | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 12 | Design of an RFQ for the CAfe Project at IMP显示文摘An RFQ has been designed for the CAFe(Chinese Accelerator Facility for super-heavy Elements)project at IMP.The RFQ,which works at 162.5 MHz and whose design current is 20 pμA. | Li Chengxing Xu Xianbo Zhang Zhouli Huang Yulu Zhang Shengxue Wang Ruoxu | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 13 | 6-5 Operation of HWRs for C-ADS Injector显示文摘There are two types of HWR cavities have been developed in IMP for C-ADS Injector.HWR010s have been used to accelerate proton from 2.1 MeV to 10 MeV.There are 12 HWR010s assembled in two CMs.The taper type HWR015s have been used to accelerate proton from 10MeV to 18.5 MeV.There are 5 HWRs assembled in the third CM.Proton beam has been accelerated to 26 MeV by HWR010,HWR015 and Spoke021 in June 2017.The beam has been accelerated to 18.5 MeV by HWR010 and HWR015.The CMs in the tunnel are shown in Fig.1. | Yue Weiming Zhang Shenghu Li Yongming Chang Wei Jiang Tiancai Zhang Shengxue Gao Zheng Wang Ruoxue Huang Shichun Pan Feng Chen Long Li Chunlong Song Yukun Guo Hao Xiong Pingran Cong Zhang Tan Teng Wan Yuqin Niu Xiaofei Bai Feng Hu Chuanfei Zhang Peng Liu Lubei Huang Yulu Zhao Yugang Guo Xiaohong You Zhiming Zhang Junhui Huang Guirong He Yuan | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 14 | 6-10 Evaluation of Power Loss on the NC QWR Cavity of a New Room-temperature Test Stand for Couplers显示文摘Room-temperature test with high power is an essential step before couplers are installed on superconducting cavities.A new room-temperature test stand is being designed at IMP.The new stand will be assembled with a NC(normal-conducting)QWR cavity.The power loss on the cavity when couplers are conditioned in traveling-wave mode has to be thoroughly evaluated.Fig.1 demonstrates the power flow in traveling-wave conditioning mode.Pe1 and Pe2 represent the power that is extracted by couplers.Pf and Pre denote the forward power and reflected power,respectively. | Chen Long Li Yongming Zhang Shenghu Jiang Tiancai Li Chunlong Wang Ruoxu He Yuan | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 15 | 6-11 SRF Power Input Coupler for HWR010 at IMP显示文摘The high power superconducting radiofrequency(SRF)input coupler is the connecting part between the SRF cavity and the RF transmission line.With the RF power transferred through the coupler,the SRF cavity can built up the electromagnetic field and then accelerate the beams.In addition to this RF transmission function,it also has to serve as a vacuum barrier for the SRF cavity vacuum.The HWR010 coupler which designed by IHEP is a single ceramic window coupler. | Li Yongming Jiang Tiancai Wang Ruoxu Zhang Shenghu Yue Weiming Xiong Pingran Li Chunlong Liu Lubei Zhang Shengxue Song Yukun He Yuan | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 16 | 6-12 Design of a Double Spoke Cavity for CADS显示文摘Spoke cavities have been developed and have apparent advantages for high current proton accelerator based on Fig.1(color online)The electromagnetic field distribution.superconductivity at low and medium energy region.As the research and the technical reserve,Institute of Modern Physics(IMP)has started the R&D program of a double spoke cavity(operating frequency 325 MHz, 0=0.52),within the framework of China Accelerator Driven System(C-ADS)project.The RF design and mechanical structure design have been finished,and two prototype cavities were manufactured in Harbin. | Jiang Tiancai Zhang Shenghu Li Yongming Yue Weiming Xiong Pingran Li Chunlong Liu Lubei Zhang Shengxue Wang Ruoxu Song Yukun Guo Hao Huang Yulu You Zhiming He Yuan | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
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