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| 1 | Isolation and Identification of Cancer Stem-Like Cells from Murine Melanoma Cell Lines显示文摘In current study,cancer stem-like cells in the murine melanoma B16F10 cells were investigated.CD phenotypes of the B16F10 cells were analyzed by flow cytometry,and the specific CD phenotype cells from the B16F10 cells were isolated by MACS.Then we used colony formation assay in soft agar media,the cell growth assay in serum-free culture media as well as the tumorigenicity investigation of the specific CD phenotype cells in C57BL/6 mice, respectively,to identify cancer stem-like cells in the B16F10 cells.The results showed that the B16F10 cells could form spherical clones in serum-free culture media,and the rate of clonegenesis of CD133 + ,CD44 + and CD44 + CD133 + cells was higher than that of CD133 - ,CD44 - and CD44 + CD133 - cells in soft agar media,respectively. The tumorigenic potential of CD133 + ,CD44 + ,CD44 + CD133 + cells and CD44 + CD133 + CD24 + cells was stronger than that of CD133 - ,CD44 - ,CD44 + CD133 - cells and CD44 + CD133 + CD24 - cells in mice,respectively.In conclusion,the CD44 + CD133 + CD24 + cells have some biological properties of cancer stem-like cells or are highly similar to the characteristics of cancer stem cells(CSC).These results provide an important method for identifying cancer stem-like cells in B16F10 cells and for further cancer target therapy. | Jun Dou Meng Pan Ping Wen Yating Li Quan Tang Lili Chu Fengshu Zhao Chuilian Jiang Weihua Hu Kai Hu Ning Gu | 2007 | Cellular & Molecular Immunology2007，4，6： | 25 |
| 2 | Chinese urbanization 2050: SD modeling and process simulation显示文摘Is Chinese urbanization going to take a long time, or can its development goal be achieved by the government in a short time? What is the highest stable urbanization level that China can reach? When can China complete its urbanization? To answer these questions, this paper presents a system dynamic(SD) model of Chinese urbanization, and its validity and simulation are justified by a stock-flow test and a sensitivity analysis using real data from 1998 to 2013. Setting the initial conditions of the simulation by referring to the real data of 2013, the multi-scenario analysis from 2013 to 2050 reveals that Chinese urbanization will reach a level higher than 70% in 2035 and then proceed to a slow urbanization stage regardless of the population policy and GDP growth rate settings; in 2050, Chinese urbanization levels will reach approximately 75%, which is a stable and equilibrium level for China. Thus, it can be argued that Chinese urbanization is a long social development process that will require approximately20 years to complete and that the ultimate urbanization level will be 75–80%, which means that in the distant future, 20–25% of China's population will still settle in rural regions of China. | GU ChaoLin GUAN WeiHua LIU HeLin | 2017 | Science China Earth Sciences2017，60，6： | 16 |
| 3 | From intrinsic dielectric loss to geometry patterns: Dual-principles strategy for ultrabroad band microwave absorption显示文摘As electromagnetic absorbers with wide absorption bandwidth are highly pursued in the cutting-edge electronic and telecommunication industries, the traditional dielectric or magnetic bulky absorbers remain concerns of extending the effective absorption bandwidth. In this work, a dual-principle strategy has been proposed to make a better understanding of the impact of utilizing conductive absorption fillers coupled with implementing artificial structures design on the absorption performance. In the comparison based on the microscopic studies, the carbon nanotubes (CNTs)-based absorbers are confined to narrow operating bandwidth and relatively fixed response frequency range, which can not fulfill the ever-growing demands in the application. With subsequent macroscopic structure design based on the CNTs-based dielectric fillers, the artificial patterns show much more broadened absorption bandwidth, covering the majority of C-band, the whole X-band, and Ku-band, due to the tailored electromagnetic parameters and more reflections and scatterings. The results suggest that the combination of developing microscopic powder/bulky absorbers and macroscopic configuration design will fundamentally extend the effective operating bandwidth of microwave. | Bin Quan Weihua Gu Jiaqi Sheng Xinfeng Lv Yuyi Mao Lie Liu Xiaogu Huang Zongjun Tian Guangbin Ji | 2021 | Nano Research2021，14，5： | 13 |
| 4 | Environmentally Friendly and Multifunctional Shaddock Peel-Based Carbon Aerogel for Thermal-Insulation and Microwave Absorption显示文摘Eco-friendly electromagnetic wave absorbing materials with excellent thermal infrared stealth property,heat-insulating ability and compression resistance are highly attractive in practical applications.Meeting the aforesaid requirements simultaneously is a formidable challenge.Herein,ultra-light carbon aerogels were fabricated via fresh shaddock peel by facile freeze-drying method and calcination process,forming porous network architecture.With the heating platform temperature of 70℃,the upper surface temperatures of the as-prepared carbon aerogel present a slow upward trend.The color of the sample surface in thermal infrared images is similar to that of the surroundings.With the maximum compressive stress of 2.435 kPa,the carbon aerogels can provide favorable endurance.The shaddock peel-based carbon aerogels possess the minimum reflection loss value(RLmin)of−29.50 dB in X band.Meanwhile,the effective absorption bandwidth covers 5.80 GHz at a relatively thin thickness of only 1.7 mm.With the detection theta of 0°,the maximum radar cross-sectional(RCS)reduction values of 16.28 dB m^(2) can be achieved.Theoretical simulations of RCS have aroused extensive interest owing to their ingenious design and time-saving feature.This work paves the way for preparing multi-functional microwave absorbers derived from biomass raw materials under the guidance of RCS simulations. | Weihua Gu Jiaqi Sheng Qianqian Huang Gehuan Wang Jiabin Chen Guangbin Ji | 2021 | Nano-Micro Letters2021，13，7： | 11 |
| 5 | Environment-Stable CoxNiy Encapsulation in Stacked Porous Carbon Nanosheets for Enhanced Microwave Absorption显示文摘Magnetic/dielectric@porous carbon composites,derived from metal–organic frameworks(MOFs)with adjustable composition ratio,have attracted wide attention due to their unique magnetoelectric properties.In addition,MOFs-derived porous carbon-based materials can meet the needs of lightweight feature.This paper reports a simple process for synthesizing stacked CoxNiy@C nanosheets derived from CoxNiy-MOFs nanosheets with multiple interfaces,which is good to the microwave response.The CoxNiy@C with controllable composition can be obtained by adjusting the ratio of Co^2+ and Ni^2+.It is supposed that the increased Co content is benefit to the dielectric and magnetic loss.Additionally,the bandwidth of CoNi@C nanosheets can take up almost the whole Ku band.Moreover,this composite has better environmental stability in air,which characteristic provides a sustainable potential for the practical application. | Xiaohui Liang Zengming Man Bin Quan Jing Zheng Weihua Gu Zhu Zhang Guangbin Ji | 2020 | Nano-Micro Letters2020，12，8： | 11 |
| 6 | The point defect and electronic structure of K doped LaCo_(0.9)Fe_(0.1)O_(3)perovskite with enhanced microwave absorbing ability显示文摘ABO_(3)perovskites,owning unique properties,have great research prospect in electromagnetic wave absorption field.Normally,doping can significantly regulate the dielectric loss,whereas the magnetic loss can be ignored.In this work,the crystal structure and electromagnetic properties can be regulated systematically by the K,Fe co-doping for LaCoO_(3)perovskites(LKCFO)under the condition of fixed F content.In addition,the obtained samples show the obvious interfacial polarization effect on accounting to the small size effect,which is conducive to the effective microwave absorption.By analyzing the evolution of the positron annihilation lifetime and the first-principles calculation of the oxygen density of states for the series of LKCFO perovskites,it is found that the charge transport characteristics will be controlled by the point defect generated by allelic doping.The point defect content decreases and then increases as the doping level rises.The prepared perovskite exhibits the lowest defect density and the largest dielectric loss capability,which indicates that the lower point defects promote electron migration and thus enhance the dielectric loss;thus,the electromagnetic wave absorption bandwidth up to 6.2 GHz is reached.In contrast,both insufficient and excessive K doping are detrimental to the enhancement of microwave absorption.Especially,the practical application value was investigated using Computer Simulation Technology(CST)simulations.The LKCFO-2 exhibits the smallest RCS value(below-10 dBm^(2))at almost-90°-90°with a thickness of 2 mm,providing an effective method for study excellent microwave absorption and scattering property. | Fan Wang Weihua Gu Jiabin Chen Yue Wu Ming Zhou Shaolong Tang Xingzhong Cao Peng Zhang Guangbin Ji | 2022 | Nano Research2022，15，4： | 7 |
| 7 | Improved electromagnetic dissipation of Fe doping LaCoO_(3)toward broadband microwave absorption显示文摘Perovskite LaCoO_(3)is of great potential in electromagnetic wave absorption considering its outstanding dielectric loss as well as the existing magnetic response with the magnetic doping.However,the dissipation mechanism of the magnetic doping on the microwave absorption is lack of sufficient investigated.In this paper,LaCo_(1-x)Fe_(x)O_(3)(x=0,0.05,0.1,0.15,0.2,0.25,0.3,LCFOs)perovskites with different Fe doping amounts were prepared successfully by the sol-gel method and subsequent heat treatment in the air atmosphere.The structure characterization carried out by the frst-principles calculations shows the effect of Fe doping on the dielectric and magnetic properties of LCFOs and the strong hybridization of Co/Fe-3d with O-2p in the LCFOs system was successfully demonstrated.Particularly,when x=0.1 and the thickness is only 1.95 mm,the LaCo_(0.9)Fe_(0.1)O_(3)exhibits the best microwave absorption performance with the minimum reflection loss(RL)value of about-41 dB.The typical samples achieve a broad effective absorption bandwidth(EAB)of 5.16 GHz(7.92-13.08 GHz),which covers the total X band(8-12 GHz).Considering that,the especial Fe doping perovskite is promising to be a candidate as efficient microwave absorbers. | Fan Wang Weihua Gu Jiabin Chen Qianqian Huang Mingyang Han Gehuan Wang Guangbin Ji | 2022 | Journal of Materials Science & Technology2022，，10： | 6 |
| 8 | Long-term anodal block stimulation at sacral anterior roots promoted recovery of neurogenic bladder function in a rabbit model of complete spinal cord injury显示文摘A complete spinal cord injury model was established in experimental rabbits using the spinal cord clip compression method.Urodynamic examination was performed 2 weeks later to determine neurogenic bladder status.The rabbits were treated with anodal block stimulation at sacral anterior roots for 4 weeks.Electrical stimulation of sacral anterior roots improved urodynamic parameters of neurogenic bladder in rabbit models of complete spinal cord injury,effectively promoted urinary function,and relieved urinary retention.Immunohistochemistry results showed that a balance was achieved among expression of muscarinic receptor subunits M2,M3,ATP-gated ion channel P2X3 receptors,and β2-adrenergic receptor,and nerve growth factor expression decreased.These results suggested that long-term sacral anterior root stimulation of anodal block could be used to treat neurogenic bladder in a rabbit model of complete spinal cord injury. | Xiaoran Wang Qi Gao Xiaoyu Yang Weihua Wang Xinquan Gu Guifeng Liu Peng Yan Ge Gao Xin Yu Yongjie Wang Jihu Lian Chaoling Shi Yao Wang Li Fan | 2012 | Neural Regeneration Research2012，7，5： | 6 |
| 9 | Interface engineering and heterometal doping Mo-NiS/Ni(OH)_(2)for overall water splitting显示文摘Developing cost-effective,efficient and bifunctional electrocatalysts is vital for both hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)application.The catalytic activity of electrocatalysts could be optimized by reasonable electronic structure regulation and increasing active sites.Herein,we report the design and fabrication of Mo-doped nickel sulfide/hydroxide heterostructures(Mo-NiS/Ni(OH)_(2))as a multisite water splitting catalyst via straightforward solvothermal and in-situ growth strategy.Based on foreign metal doping and interface interaction,the electronic conductivity of heterostructures is improved and the charge transfer kinetics across the interface is promoted,which are demonstrated by the theoretical calculations.Mo-NiS/Ni(OH)_(2)electrocatalyst is endowed with high electrocatalytic performance for water splitting and remarkable durability in alkaline electrolyte.It exhibits the low overpotential of 186 and 74 mV at 10 mA·cm^(-2)for OER and HER,respectively.Importantly,after continuously working for 50 h,the current densities of HER and OER both show negligible degeneration.Even,the resulting Mo-NiS/Ni(OH)_(2)better catalyzes water splitting,yielding a current density of 10 mA·cm^(-2)at a cell voltage of 1.5 V and outperforming Pt/C-IrO2 couple(1.53 V).This result demonstrates that transition metal doping and heterogeneous interface engineering are useful means for conventional catalyst design. | Hua Zhang Baojuan Xi Yu Gu Weihua Chen Shenglin Xiong | 2021 | Nano Research2021，14，10： | 4 |
| 10 | Heterostructure design of Fe^(3)N alloy/porous carbon nanosheet composites for efficient microwave attenuation显示文摘The self-dissipation and attenuation capacity of materials play an important role in realizing efficient electromagnetic absorption,in this case,the roles of macroscopic composition and micro-structure should be emphasized simultaneously in the reasonable design of microwave absorbent.Given that,Fe_(3)N alloy embedded in two-dimensional porous carbon composites were fabricated via facile sol-gel and sacrificial template methods.Satisfactorily,the magnetic/dielectric materials combination and porous structure introduction are conductive to the optimization of impedance matching property,as result of the enhancement of microwave absorption capacity.In addition,sufficient magnetic loss capacity,strong conductivity as well as polarization attenuation bring about the outstanding microwave absorbing performance with an effective absorption bandwidth of 6.76 GHz and a minimum reflection loss value of-65.6 d B.It is believed that this work not only lay a foundation to achieve microwave response materials in a wide frequency range,but also emphasize the significant role of the component selection and structural design. | Weihua Gu Xiaoqing Cui Jing Zheng Jiwen Yu Yue Zhao Guangbin Ji | 2021 | Journal of Materials Science & Technology2021，，8： | 3 |
| 11 | Cu_(3)P nanoparticles confined in nitrogen/phosphorus dual-doped porous carbon nanosheets for efficient potassium storage显示文摘Immobilizing primary electroactive nanomaterials in porous carbon matrix is an effective approach for boosting the electrochemical performance of potassium-ion batteries (PIBs) because of the synergy among functional components. Herein, an integrated hybrid architecture composed of ultrathin Cu_(3)P nanoparticles (~20 nm) confined in porous carbon nanosheets (Cu_(3)P⊂NPCSs) as a new anode material for PIBs is synthesized through a rational self-designed self-templating strategy. Benefiting from the unique structural advantages including more active heterointerfacial sites, intimate and stable electrical contact, effectively relieved volume change, and rapid K^(+) ion migration, the Cu_(3)P⊂NPCSs indicate excellent potassium-storage performance involving high reversible capacity, exceptional rate capability, and cycling stability. Moreover, the strong adsorption of K^(+) ions and fast potassium-ion reaction kinetics in Cu_(3)P⊂NPCSs is verified by the theoretical calculation investigation. Noted, the intercalation mechanism of Cu_(3)P to store potassium ions is, for the first time, clearly confirmed during the electrochemical process by a series of advanced characterization techniques. | Yuanxing Yun Baojuan Xi Yu Gu Fang Tian Weihua Chen Jinkui Feng Yitai Qian Shenglin Xiong | 2022 | Journal of Energy Chemistry2022，31，3： | 2 |
| 12 | Identifying tumor stem-like cells in mouse melanoma cell lines by analyzing the characteristics of side population cells显示文摘 | Jun Dou Ping Wen Weihua Hu Yating Li Yun Wu Chunsheng Liu Fengshu Zhao Kai Hu Jing Wang Chuilian Jiang Xiangfeng He Ning Gu | 2009 | Cell Biology International2009，，8： | 1 |
| 13 | Modification of collagen with a natural derived cross-linker, alginate dialdehyde显示文摘 | Yang Hu Lan Liu Zhipeng Gu Weihua Dan Nianhua Dan Xixun Yu | 2014 | Carbohydrate Polymers2014，，： | 1 |
| 14 | Investigation of inclusion complex of cilnidipine with hydroxypropyl-β-cyclodextrin显示文摘 | Liandong Hu Hailei Zhang Weihua Song Deliang Gu Qiaofeng Hu | 2012 | Carbohydrate Polymers2012，，4： | 1 |
| 15 | Corrosion of, and cellular responses to Mg–Zn–Ca bulk metallic glasses显示文摘 | Xuenan Gu Yufeng Zheng Shengping Zhong Tingfei Xi Junqiang Wang Weihua Wang | 2009 | Biomaterials2009，，6： | 1 |
| 16 | Joint opti- mization of pavement maintenance and resurfacing planning 显示文摘 | Gu Weihua Ouyang Yanfeng Samer M | 2012 | Transportation Research Part B2012，46，4： | 1 |
| 17 | A novel algorithm for transmission image reconstruction of tomographic gamma scaners显示文摘It is difficult to develop image reconstruction algorithms for tomographic gamma scanning based on drummed radioactive residues or wastes.In this paper,a novel reconstruction algorithm of transmission image for tomographic gamma scanning is proposed.It is based on the conventional transmission equation and equivalent gamma-ray track length modified by a Monte Carlo method.The algorithm is implemented by simulating the samples on the established platform.For the verification experiments of the algorithm,several cubic voxel samples were designed and manufactured.Experimental tests were conducted.The tomographic gamma scanning of transmission images is compared with the linear attenuation coefficients by the simulated values and experimental data with the algorithm and the reference values.The results show that the absolute relative errors of the reconstructed images are less than 5%. | ZHANG Quanhu HUI Weihua WANG Dong HE Bin GU Zhongmao LI Ze QIAN Shaojun | 2010 | Nuclear Science and Techniques2010，21，3： | 1 |
| 18 | Adsorption/desorption characteristics and separation of anthocyanins and polyphenols from blueberries using macroporous adsorbent resins显示文摘 | Timothy J. Buran Amandeep K. Sandhu Zheng Li Cheryl R. Rock Weihua W. Yang Liwei Gu | 2014 | Journal of Food Engineering2014，，： | 1 |
| 19 | Butterfly-wing hierarchical metallic glassy nanostructure for surface enhanced Raman scattering显示文摘The surface-enhanced Raman spectroscopy(SERS)is a technique for the detection of analytes on the surface with an ultrahigh sensitivity down to the atomic-scale,yet the fabrication of SERS materials such as nanoparticles or arrays of coinage metals often involve multiple complex steps with the high cost and pollution,largely limiting the application of SERS.Here,we report a complex hierarchical metallic glassy(MG)nanostructure by simply replicating the surface microstructure of butterfly wings through vapor deposition technique.The MG nanostructure displays an excellent SERS effect and moreover,a superhydrophobicity and self-cleaning behavior.The SERS effect of the MG nanostructure is attributed to the intrinsic nanoscale structural heterogeneities on the MG surface,which provides a large number of hotspots for the localized electromagnetic field enhancement affirmed by the finite-difference time-domain(FDTD)simulation.Our works show that the MG could be a new potential SERS material with low cost and good durability,well extending the functional application of this kind of material. | Hongyu Jiang Jing Li Chengrong Cao Xiaozhi Liu Ming Liu Yutian Shen Yanhui Liu Qinghua Zhang Weihua Wang Lin Gu Baoan Sun | 2019 | Nano Research2019，12，11： | 1 |
| 20 | The national multi-center artificial intelligent myopia prevention and control project显示文摘In recent years,the incidence of myopia has increased at an alarming rate among children and adolescents in China.The exploration of an effective prevention and control method for myopia is in urgent need.With the development of information technology in the past decade,artificial intelligence with the Internet of Things technology(AIoT)is characterized by strong computing power,advanced algorithm,continuous monitoring,and accurate prediction of long-term progression.Therefore,big data and artificial intelligence technology have the potential to be applied to data mining of myopia etiology and prediction of myopia occurrence and development.More recently,there has been a growing recognition that myopia study involving AIoT needs to undergo a rigorous evaluation to demonstrate robust results. | Xun Wang Yahan Yang Yuxuan Wu Wenbin Wei Li Dong Yang Li Xingping Tan Hankun Cao Hong Zhang Xiaodan Ma Qin Jiang Yunfan Zhou Weihua Yang Chaoyu Li Yu Gu Lin Ding Yanli Qin Qi Chen Lili Li Mingyue Lian Jin Ma Dongmei Cui Yuanzhou Huang Wenyan Liu Xiao Yang Shuiming Yu Jingjing Chen Dongni Wang Zhenzhe Lin Pisong Yan Haotian Lin Chinese Association of Artificial Intelligence,Medical Artificial Intelligence Branch of Guangdong Medical Association | 2021 | Intelligent Medicine2021，1，2： | 1 |
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