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| 1 | Almost Periodic Solutions for Nonlinear Duffing Equations | Zeng Weiyao (Department of Mathematics,Changsha Railway University,Changsha 410075,China) | 1997 | Acta Mathematica Sinica,English Series1997，13，3： | 9 |
| 2 | On the characteristics of ADRC:a PID interpretation显示文摘Dear editor,This study reports the discovery of active disturbance rejection control(ADRC).Second-order linear ADRC(LADRC),the basic and most popular ADRC,can be interpreted as a modified proportional-integral-derivative(PID)control.LADRC filters the PID feedback compensator with a second-order low-pass filter;it also adds a pre-filter. | Huiyu JIN Jingchao SONG Weiyao LAN Zhiqiang GAO | 2020 | Science China(Information Sciences)2020，63，10： | 9 |
| 3 | Efficacy of platinum in advanced triple-negative breast cancer with germline BRCA mutation determined by next generation sequencing显示文摘Objective:To compare the efficacy of platinum-and non-platinum-based regimens as first-line treatment for advanced triple-negative breast cancer(TNBC)and analyze the relationship between their efficacy and BRCA gene status.Methods:Retrospectively analyze clinical data of 220 patients diagnosed pathologically with advanced TNBC and treated at the Department of Breast Oncology,Peking University Cancer Hospital from 2013 to 2018 and evaluate the efficacy of chemotherapy.A total of 114 patients had BRCA1/2 gene tested by next generation sequencing(NGS)using peripheral blood,and we analyzed the correlation between their efficacy and BRCA1/2 gene status.Results:Non-platinum-based chemotherapy(NPCT)was administered to 129 and platinum-based chemotherapy(PBCT)to 91 study patients.The clinical benefit rate(CBR)and median progression-free survival(PFS)were not statistically different between NPCT and PBCT groups.The median overall survival(OS)was 30.0 and 22.5 months for PBCT and NPCT group,respectively[P=0.090,hazard ratios(HR)=0.703].BRCA status was assessed in 114 patients,14 of whom had deleterious germline BRCA1/2(g BRCA)mutations(seven in each group).In PBCT group,the CBR was 85.7%and 35.1%for patients with and without deleterious g BRCA mutations,respectively(P=0.039).The median PFS were 14.9 and 5.3 months and median OS were 26.5 and 15.5 months for patients with and without deleterious g BRCA mutations,respectively(P=0.001,P=0.161,respectively).Patients in PBCT group had significantly greater rates of grade 3-4 anemia(5.5%vs.0%)and thrombocytopenia(8.8%vs.0%),whereas palmar-plantar erythrodysesthesia(12.4%vs.0%)and peripheral neuropathy(8.6%vs.1.1%)occurred more frequently in NPCT group.Conclusions:Platinum-based regimens are more effective in patients with deleterious g BRCA mutations,but no difference in patients without BRCA gene mutations,so non-platinum is an option in patients without BRCA gene mutations considering the toxicity and side effect.And we recommend that patients with advanced TNBC should have BRCA gene test. | Nan Wang Kun Li Wenfa Huang Weiyao Kong Xiaoran Liu Weijie Shi Feng Xie Hanfang Jiang Guohong Song Lijun Di Quanren Wang Jianjun Yu Huiping Li | 2020 | Chinese Journal of Cancer Research2020，32，2： | 7 |
| 4 | The R2R3-type MYB transcription factor MdMYB90-like is responsible for the enhanced skin color of an apple bud sport mutant显示文摘The anthocyanin content in apple skin determines its red coloration,as seen in a Fuji apple mutant.Comparative RNA-seq analysis was performed to determine differentially expressed genes at different fruit development stages between the wild-type and the skin color mutant.A novel R2R3-MYB transcription factor,MdMYB90-like,was uncovered as the key regulatory gene for enhanced coloration in the mutant.The expression of MdMYB90-like was 21.3 times higher in the mutant.MdMYB90-like regulates anthocyanin biosynthesis directly through the activation of anthocyanin biosynthesis genes and indirectly through the activation of other transcription factors that activate anthocyanin biosynthesis.MdMYB90-like bound to the promoters of both structural genes(MdCHS and MdUFGT)and other transcription factor genes(MdMYB1 and MdbHLH3)in the yeast one-hybrid system,electrophoretic mobility shift assay,and dual-luciferase assay.Transgenic analysis showed that MdMYB90-like was localized in the nucleus,and its overexpression induced the expression of other anthocyanin-related genes,including MdCHS,MdCHI,MdANS,MdUFGT,MdbHLH3,and MdMYB1.The mutant had reduced levels of DNA methylation in two regions(−1183 to−988 and−2018 to−1778)of the MdMYB90-like gene promoter,which might explain the enhanced expression of the gene and the increased anthocyanin content in the mutant apple skin. | Chao Sun Chunming Wang Wang Zhang Shuai Liu Weiyao Wang Xinyi Yu Tao Song Maxwell Yu Weichang Yu Shenchun Qu | 2021 | Horticulture Research2021，8，1： | 6 |
| 5 | Flavone Content and Bioactivity of Aqueous-Ethanolic Extracts of Phellinus Fruit Bodies显示文摘The flavone content of aqueous ethanolic extracts of Phellinus fruit bodies obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the seven Phellinus samples generated very similar HPLC profiles in qualitative terms although the areas of several peaks varied according to the sample type indicating quantitative differences in the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content. | HAO Ruixia ZHOU Shuai YANG Yan XI Junzhe LI Weiyao TANG Qingjiu WANG Chenguang | 2008 | 食用菌学报2008，15，2： | 6 |
| 6 | Spatial integration of oasis city group around the western margins of the Tarim Basin显示文摘In this paper,the oasis cities in Kashgar Prefecture and Kizilsu Kirgiz Autonomous Prefecture are taken as an example,through the factor analysis,spatial attraction interaction model and location quotient methods,urban hierarchy system,the intensity of urban economic ties,economic subordination degree,and structure of city functions were analyzed. The results indicated:(1) The urban hierarchy system takes Kashgar city as the main center,Artux city,Yarkant county and Maralbexi county as the sub-centers; (2) The intensity of economic ties among Kashgar city and each county is much higher than others. The interaction of Kashgar city,Shufu county and Shule county are the strongest,and the economic ties of Yarkant,Kagilik,Poskam counties are relatively close; All cities in the study area are economically subordinate to Kashgar city. (3) Three cities of Kashgar city,Shufu county and Shule county should connect strongly,with Kashgar city as the core. The cities and towns along the Southern Xinjiang Railway and along National Road 315 should be regarded as two strips,and the two city strips along the border,and the city strip along Provincial Road 215 should be treated as three axes. The ring structure strategy of 'core ring,closer ring and radiated ring' was proposed. (4) It was proposed to build Kashgar city group in the north,and Yarkant city group in the south,Maralbexi city group in the southeast,and Taxkorgan border city group with four inner groups' development strategy. | Yang, Yu Zhang, XiaoLei Lei, Jun Dong, Wen Zeng, WeiYao Gao, Chao | 2010 | Journal of Arid Land2010，2，3： | 4 |
| 7 | Combined peripheral natural killer cell and circulating tumor cell enumeration enhance prognostic efficiency in patients with metastatic triple-negative breast cancer显示文摘Objective:Triple-negative breast cancer(TNBC)is a heterogeneous disease with poor prognosis.Circulating tumor cells(CTCs)are a promising predictor for breast cancer prognoses but their reliability regarding progression-free survival(PFS)is controversial.We aim to verify their predictive value in TNBC.Methods:In present prospective cohort study,we used the Pep@MNPs method to enumerate CTCs in baseline blood samples from 75 patients with TNBC(taken at inclusion in this study)and analyzed correlations between CTC numbers and outcomes and other clinical parameters.Results:Median PFS was 6.0(range:1.0–25.0)months for the entire cohort,in whom we found no correlations between baseline CTC status and initial tumor stage(P=0.167),tumor grade(P=0.783)or histological type(P=0.084).However,among those getting first-line treatment,baseline CTC status was positively correlated with ratio of peripheral natural killer(NK)cells(P=0.032),presence of lung metastasis(P=0.034)and number of visceral metastatic site(P=0.037).Baseline CTC status was predictive for PFS in first-line TNBC(P=0.033),but not for the cohort as a whole(P=0.118).This prognostic limitation of CTC could be ameliorated by combining CTC and NK cell enumeration(P=0.049).Conclusions:Baseline CTC status was predictive of lung metastasis,peripheral NK cell ratio and PFS in TNBC patients undergoing first-line treatment.We have developed a combined CTC-NK enumeration strategy that allows us to predict PFS in TNBC without any preconditions. | Xiaoran Liu Ran Ran Bin Shao Hope S.Rugo Yanlian Yang Zhiyuan Hu Zewen Wei Fengling Wan Weiyao Kong Guohong Song Hanfang Jiang Xu Liang Ruyan Zhang Ying Yan Guobing Xu Huiping Li | 2018 | Chinese Journal of Cancer Research2018，30，3： | 4 |
| 8 | Magnetic plasmon resonances in nanostructured topological insulators for strongly enhanced light-MoS_(2) interactions显示文摘Magnetic resonances not only play crucial roles in artificial magnetic materials but also offer a promising way for light control and interaction with matter.Recently,magnetic resonance effects have attracted special attention in plasmonic systems for overcoming magnetic response saturation at high frequencies and realizing high-performance optical functionalities.As novel states of matter,topological insulators(TIs)present topologically protected conducting surfaces and insulating bulks in a broad optical range,providing new building blocks for plasmonics.However,until now,high-frequency(e.g.visible range)magnetic resonances and related applications have not been demonstrated in TI systems.Herein,we report for the first time,to our knowledge,a kind of visible range magnetic plasmon resonances(MPRs)in TI structures composed of nanofabricated Sb_(2)Te_(3) nanogrooves.The experimental results show that the MPR response can be tailored by adjusting the nanogroove height,width,and pitch,which agrees well with the simulations and theoretical calculations.Moreover,we innovatively integrated monolayer MoS_(2) onto a TI nanostructure and observed strongly reinforced light-MoS_(2) interactions induced by a significant MPR-induced electric field enhancement,remarkable compared with TI-based electric plasmon resonances(EPRs).The MoS_(2) photoluminescence can be flexibly tuned by controlling the incident light polarization.These results enrich TI optical physics and applications in highly efficient optical functionalities as well as artificial magnetic materials at high frequencies. | Hua Lu Zengji Yue Yangwu Li Yinan Zhang Mingwen Zhang Wei Zeng Xuetao Gan Dong Mao Fajun Xiao Ting Mei Weiyao Zhao Xiaolin Wang Min Gu Jianlin Zhao | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 9 | Rigid-Flexible Coupling Dynamic Analysis of Sub-Launched Vehicle During the Vertical Tube-Exit Stage显示文摘During the launching stage,hydrodynamic pressure and adapters' reaction loads can influence the vehicle's rigid motion as well as cause its structural vibration,which is a typical rigid-flexible coupling dynamic problem. This paper presents a 2-D rigid-flexible coupling model to calculate the vehicle's dynamic responses in that period.The vehicle was equivalent to a flexure beam with axial deformation. Hybrid coordinate and modal superposition methods were used to describe its large rigid displacement and small deformation. By the second Lagrange equation,the vehicle centroid's displacements,rotational angle and modal coordinates were chosen as generalized coordinates and then the vehicle 's rigid-flexible coupling dynamic equations were obtained. By numerical simulation,the results of vehicle's motion parameters and transverse internal loads were acquired.The calculation results showed that differences of the vehicle's motion parameters between the rigid-flexible coupling model and the rigid body assumption are noticeable and the peak magnitude of the vehicle's transverse internal loads in the rigid-flexible coupling model is higher remarkably than that in the rigid body assumption. | Weiyao Zhang Jingbo Gao Cong Wang | 2015 | Journal of Harbin Institute of Technology(New Series)2015，22，2： | 3 |
| 10 | Composite nonlinear feedback control for output regulation problem of linear discrete-time systems with input saturation显示文摘Transient performance for output regulation problems of linear discrete-time systems with input saturation is addressed by using the composite nonlinear feedback(CNF) control technique. The regulator is designed to be an additive combination of a linear regulator part and a nonlinear feedback part. The linear regulator part solves the regulation problem independently which produces a quick output response but large oscillations. The nonlinear feedback part with well-tuned parameters is introduced to improve the transient performance by smoothing the oscillatory convergence. It is shown that the introduction of the nonlinear feedback part does not change the solvability conditions of the linear discrete-time output regulation problem. The effectiveness of transient improvement is illustrated by a numeric example. | Chongwen Wang Xing Chu Weiyao Lan | 2014 | Journal of Systems Engineering and Electronics2014，25，6： | 2 |
| 11 | Collective rotations of fission isomers in actinide nuclei显示文摘Using the total-Routhian-surface(TRS)method,the rotational behaviors of fission isomers in the second well of actinide nuclei234 242U,236 244Pu and238 246Cm were investigated.The pairing-deformation-frequency self-consistent TRS calculations reproduced reasonably the experimental moments of inertia extracted from spectroscopic data.It is calculated that,in these largelyelongated(β2≈0.65 andβ4≈0.03)fission isomers,theν12[981]neutron andπ12+[651]proton align simultaneously at rotational frequencyω≈0.4 0.6 MeV(corresponding to spin I≈80),which leads to clear upbending in moments of inertia(MoI’s).Our calculations have indicated that the hexadecapole deformationβ4influenced significantly the frequency of the rotational alignment of the proton12+[651]orbit. | XIE KePing KE WeiYao LIANG WuYang FU XiMing JIAO ChangFeng PEI JunChen XU FuRong | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，2： | 2 |
| 12 | Transient Performance Improvement in Tracking Control for a Class of Nonlinear Systems with Input Saturation显示文摘这份报纸探讨合成非线性的反馈(CNF ) 为有输入浸透的单个产量的非线性的系统与好短暂性能指向追踪改变引用的一时间的 singleinput 的一个类的控制。CNF 控制法律由一条追踪的控制法律和一个表演赔偿者组成。追踪的控制法律被设计驱使系统的输出追踪很快改变引用目标的时间,当性能赔偿者被用来减少追踪的控制法律引起的 overshoot 时。靠近环的系统的稳定性被建立。设计过程和靠近环的系统的短暂性能的改进与一个数字例子和控制凡·德尔·波尔振荡器被说明。 | LU Tao LAN Weiyao LI Zhibin | 2018 | Journal of Systems Science & Complexity2018，31，1： | 2 |
| 13 | Preparation and properties of hollow silica tubes/bismaleimide/diallylbisphenol A composites with improved toughness, dielectric properties, and flame retardancy显示文摘 | WeiYao AijuanGu GuozhengLiang DongxianZhuo LiYuan | 2012 | Technol2012，，3： | 1 |
| 14 | RNA interference targeting VP1 inbihits Foot-and-Mouth disease virus replication in BHK-21 and Suckling mice显示文摘 | Weizao Chen Weiyao Yan Qingyun Du | 2004 | Virology2004，78，13： | 1 |
| 15 | Exponential dichotomies and transversal homoclinic orbits in degenerate cases显示文摘 | Weiyao Zeng | 1995 | Journal of Dynamics and Differential Equations1995，，4： | 1 |
| 16 | The influence of friction on contouring accuracy of a Cartesian guided tripod machine tool显示文摘 | CHEN Jenqshyong KUO Yaohung HSU Weiyao | 2006 | International Journal of Advanced Manufacturing Technology2006，30，5： | 1 |
| 17 | Periodic solution and almost periodic solution of differential equation in critical case显示文摘 | Zeng Weiyao | 1987 | Ann of Diff Eqs1987，3，4： | 1 |
| 18 | Characterization of 18 polymorphie microsatellite loci in the red - crowned crane ( Grus japonensis), an endangered bird 显示文摘 | Hongfei Zou Haiyan Dong Weiyao kong | 2010 | Animal Science Journal2010，81，4： | 1 |
| 19 | Deployment and Exploration of a Gas Storage Well Pattern Based on the Threshold Radius显示文摘To tackle the problem that wells that are deployed in a specific pattern based on the requirements of gas reservoir development are not suitable for gas storage,we have conducted concentrically circular injection and production simulation experiments for gas storage,discovered the existence of a threshold radius,denoted by Rt,and derived the expression for Rt.Based on the analysis and discussion results,we propose a strategy for deploying gas storage wells in specific patterns.The expression for Rt shows that it is affected by factors such as the gas storage gas production/injection time,the upper pressure limit,the lower pressure limit,the bottomhole flow pressure at the ends of injection and production,the and permeability.The analysis and discussion results show that the Rt of a gas storage facility is much smaller than the Rt for gas reservoir development.In the gas storage facilities in China,the Rt for gas production is less than the Rt for the gas injection,and Rt increases with the difference in the operating pressure and with permeability K.Based on the characteristics of Rt,we propose three suggestions for gas storage well pattern deployment:(1)calculate Rt according to the designed functions of the gas storage facility and deploy the well pattern according to Rt;(2)deploy sparser,large-wellbore patterns in high-permeability areas and denser,small-wellbore patterns in high-permeability areas;and(3)achieve the gas injection well pattern by new drilling,and the gas production well pattern through a combination of the gas injection well pattern and old wells.By assessing a gas storage facility with a perfect well pattern after a number of adjustments,we found that the Rt of the 12 wells calculated in this paper is basically close to the corresponding actual radius,which validates our method.The results of this study provide a methodological basis for well pattern deployment in new gas storage construction. | TANG Ligen ZHU Weiyao ZHU Huayin SUN Chunhui YANG Fenglai WANG Yan Li Xiaorui Li Haiming CHU Guangzhen WANG Jieming KONG Debin YUE Ming LIU Yuwei HUANG Kun | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 20 | Periodic solution and almost periodic solution of differential in critical case显示文摘 | Zeng Weiyao | 1987 | Ann of Diff Eqs1987，3，4： | 1 |
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