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| 1 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021,31,4: | 16 |
| 2 | On comparison of modified ADRCs for nonlinear uncertain systems with time delay显示文摘To tackle systems with both uncertainties and time delays, several modified active disturbance rejection control(ADRC) methods, including delayed designed ADRC(DD-ADRC), polynomial based predictive ADRC(PP-ADRC), Smith predictor based ADRC(SP-ADRC) and predictor observer based ADRC(PO-ADRC), have been proposed in the past years. This paper is aimed at rigorously investigating the performance of these modified ADRCs, such that the improvements of each method can be demonstrated.The capability to tackle time delay, the necessity of stable open loop and the performance of rejecting uncertainties for these methods are fully studied and compared. It is proven that large time delay cannot be tolerated for the stability of the closed-loop systems based on DD-ADRC and PP-ADRC. Moreover, stable open loop is shown to be necessary for stabilizing the closed-loop systems based on SP-ADRC. Furthermore,the performance of rejecting the 'total disturbance' at low frequency for these modified ADRCs is evaluated and quantitatively discussed. Finally, the simulations of a boiler turbine system illustrate the theoretical results. | Sen CHEN Wenchao XUE Sheng ZHONG Yi HUANG | 2018 | Science China(Information Sciences)2018,61,7: | 16 |
| 3 | Tuning of Sampled-Data ADRC for Nonlinear Uncertain Systems显示文摘This paper concerns with the parameters tuning of active disturbance rejection control(ADRC) for a class of nonlinear systems with sampling rate not fast enough. The theoretical results show the quantitative relationship between the sampling rate, the parameters of ADRC, the size of uncertainties in system and the properties of the closed-loop system. Furthermore, the capability of the sampled-data ADRC under given sampling rate is quantitatively discussed. | XUE Wenchao HUANG Yi | 2016 | Journal of Systems Science & Complexity2016,29,5: | 8 |
| 4 | Analysis on gust factor of tropical cyclone strong wind over different underlying surfaces显示文摘Based on one year gradient wind data and the wind data of a strong typhoon observed by three meteorological towers located on the coast and at the inshore sea,the underlying surfaces of the meteorological towers were classified and the roughness lengths were calculated quantitatively.On the basis of strong wind characteristic representative assessment and sample selection on the wind data of strong typhoon Hagupit,the gust factor variation characteristics of tropical cyclones under different underlying surfaces were analyzed.The observed fact and variation rule were found as follows:1) The roughness lengths under neutral atmospheric condition which were calculated using logarithmic wind profile fitting based on the observation data can describe the slight change of the underlying surface objectively.2) The gust factor of strong typhoon wind didn't have variation trends with wind speed.But the variation amplitude of the gust factor was rather large over rough underlying surface which had pronounced effect on the numerical design of structural engineering.3) The variation of the gust factor with height satisfied power law or logarithmic law.The power law fitting was more suitable for smooth underlying surface while the logarithmic fitting was better over rough underlying surface.4) The observation data also suggested that the relationship between gust factor and roughness length can be described by power or linear equation.5) The gust factor observed in this typhoon case was different from the gust factor recommended by WMO:The gust factor of the offshore wind came from rough underlying surface was higher than the value recommended by WMO while the gust factor of the onshore wind came from smooth underlying surface is less than the WMO recommended value. | CHEN WenChao SONG LiLi ZHI ShiQun HUANG HaoHui QIN Peng | 2011 | Science China(Technological Sciences)2011,54,10: | 7 |
| 5 | On extended state based Kalman filter design for a class of nonlinear time-varying uncertain systems显示文摘This paper considers the filtering problem for a class of multi-input multi-output systems with nonlinear time-varying uncertain dynamics, random process and measurement noise. An extended state based Kalman filter, with the idea of timely estimating the unknown dynamics, is proposed for better robustness and higher estimation precision. The stability of the proposed filter is rigorously proved for nonlinear timevarying uncertain system with weaker stability condition than the extended Kalman filter, i.e., the initial estimation error, the uncertain dynamics and the noises are only required to be bounded rather than small enough. Moreover, quantitative precision of the proposed filter is theoretically evaluated. The proposed algorithm is proved to be the asymptotic unbiased minimum variance filter for constant uncertainty. The simulation results of some benchmark examples demonstrate the feasibility and effectiveness of the method. | Wenyan BAI Wenchao XUE Yi HUANG Haitao FANG | 2018 | Science China(Information Sciences)2018,61,4: | 7 |
| 6 | On Designing Consistent Extended Kalman Filter显示文摘This paper studies the consistency of the extended Kalman filter(EKF) for a kind of nonlinear systems. Based on the EKF algorithm, the authors propose the quasi-consistent EKF(QCEKF)as well as the tuning law for its parameters. The quasi-consistency of the proposed algorithm is proved.Finally, the feasibility of the algorithm is illustrated by the numerical simulation on an orbit determination example. | JIANG Yanguang HUANG Yi XUE Wenchao FANG Haitao | 2017 | Journal of Systems Science & Complexity2017,30,4: | 7 |
| 7 | Personalized Privacy-Preserving Trajectory Data Publishing显示文摘Due to the popularity of mobile internet and location-aware devices,there is an explosion of location and tra jectory data of moving objects.A few proposals have been proposed for privacy preserving tra jectory data publishing,and most of them assume the attacks with the same adversarial background knowledge.In practice,different users have different privacy requirements.Such non-personalized privacy assumption does not meet the personalized privacy requirements,meanwhile,it looses the chance to achieve better utility by taking advantage of differences of users' privacy requirements.We study the personalized tra jectory k-anonymity criterion for trajectory data publication.Specifically,we explore and propose an overall framework which provides privacy preserving services based on users' personal privacy requests,including tra jectory clustering,editing and publication.We demonstrate the efficiency and effectiveness of our scheme through experiments on real world dataset. | LU Qiwei WANG Caimei XIONG Yan XIA Huihua HUANG Wenchao GONG Xudong | 2017 | Chinese Journal of Electronics2017,26,2: | 6 |
| 8 | On ADRC for non-minimum phase systems: canonical form selection and stability conditions显示文摘活跃骚乱拒绝控制(ADRC ) 由韩静清教授求婚了首先把植物动力学归结为它的正规形式,通常在串联综合者,标准控制器能为被采用遇见设计说明形式。这份报纸为非最小的阶段系统与正规形式的选择担心。特别地,由采用众所周知的可控制的正规形式,如此的系统的无常能在输出隧道在州的空格模型,在控制隧道的模型和其它被划分成二项条款,这被显示出。必要、足够的条件与建议正规形式和 ADRC 为靠近环的系统的稳定性被获得。另外,由显示出扩大系统的 detectability 以及系统的某些信息的必要性零,我们在场为非最小的阶段的设计 ADRC 的基本指南不明确的系统。 | Wenchao XUE Yi HUANG Zhiqiang GAO | 2016 | Control Theory and Technology2016,14,3: | 6 |
| 9 | Combining User-Based and Item-Based Models for Collaborative Filtering Using Stacked Regression显示文摘Collaborative filtering can be classified into user-based or item-based methods according to different assumptions. Our experiment results show that both userbased and item-based methods can reach a certain degree of accuracy, but the recommendation coverage of these two methods is significantly different. This paper qualitatively analyzes the advantages and disadvantages of such two methods, and found that user-based methods advantage in recommending popular items while item-based methods perform better at suggesting long tail items. Based on this analysis, we proposes a novel machine learning framework to systematically combine both. We train a model for each user-item pair for discovering the local preference of the user or item over both methods, and effectively combine user-based and item-based predictions using the preference information. Experiment results show that our approach can significantly improve the recommendation quality, and to a certain extend, alleviate the data sparsity problem. | LIU Qingwen XIONG Yan HUANG Wenchao | 2014 | Chinese Journal of Electronics2014,23,4: | 5 |
| 10 | A Trusted Ad Hoc Routing Protocol Based on Fuzzy Mathematics显示文摘 | GONG Xudong XIONG Yan LU Qiwei MIAO Puyou HUANG Wenchao | 2013 | Chinese Journal of Electronics2013,22,1: | 5 |
| 11 | Tribological and anti-corrosion performance of epoxy resin composite coatings reinforced with differently sized cubic boron nitride(CBN)particles显示文摘A series of high solid content(30 wt%)epoxy resin(EP)composite coatings reinforced with differently sized cubic boron nitride(CBN)particles were fabricated successfully on 304 L stainless steel.Polydopamine(PDA)was used to improve the dispersibility of CBN particles in EP.The structural and morphological features of the CBN particles and the composite coatings were characterized by Raman spectroscopy,scanning electron microscopy(SEM),and transmission electron microscopy(TEM).Moreover,a UMT-3 tribometer and surface profiler were used to investigate the tribological behaviors of the as-prepared composite coatings.Electrochemical impedance spectroscopy(EIS)and Tafel analysis were used to investigate the coatings'anti-corrosion performance.The results demonstrated that the CBN fillers could effectively enhance the tribological and anti-corrosion properties of the EP composite coatings.In addition,when the additive proportion of the microsized(5μm)and nanosized(550 nm)CBN particles was 1:1,the tribological property of the EP composite coatings was optimal for dry sliding,which was attributed to the load carrying capability of the microsized CBN particles and the toughening effect of the nanosized CBN particles.However,when the additive proportion of the microsized and nanosized CBN particles was 2:1,the tribology and corrosion resistance performance were optimal in seawater conditions.We ascribed this to the load-carrying capacity of the microparticles,which played a more important role under the seawater lubrication condition,and the more compact structure,which improved the electrolyte barrier ability for the composite coatings. | Zhiping HUANG Wenjie ZHAO Wenchao ZHAO Xiaojing CI Wentao LI | 2021 | Friction2021,9,1: | 5 |
| 12 | The occurrence of diffuse axonal injury in the brain:associated with the accumulation and clearance of myelin debris显示文摘The accumulation of myelin debris may be a major contributor to the inflammatory response after diffuse axonal injury. In this study, we examined the accumulation and clearance of myelin debris in a rat model of diffuse axonal injury. Oil Red O staining was performed on sections from the cerebral cortex, hippocampus and brain stem to identify the myelin debris. Seven days after diffuse axonal injury, many Oil Red O-stained particles were observed in the cerebral cortex, hippocampus and brain stem. In the cerebral cortex and hippocampus, the amount of myelin debris peaked at 14 days after injury, and decreased significantly at 28 days. In the brain stem, the amount of myelin debris peaked at 7 days after injury, and decreased significantly at 14 and 28 days. In the cortex and hippocampus, some myelin debris could still be observed at 28 days after diffuse axonal injury. Our findings suggest that myelin debris may persist in the rat central nervous system after diffuse axonal injury, which would hinder recovery. | Liang Wen Jun Xu Tianxiang Zhan Hao Wang Xin Huang Wenchao Liu Xiaofeng Yang Renya Zhan | 2014 | Neural Regeneration Research2014,9,21: | 4 |
| 13 | New Zircon U-Pb Age of the Babu Ophiolites in Southeast Yunnan,China and Constrains of Plate Subduction Time显示文摘Objective The Babu ophiolite in Malipo County of southeastern Yunnan is interpreted as remanant ocean crust and represents a possible branch of Paleo-Tethyan Ocean in South China.It consists mainly of mafic and ultramafic rocks.These rocks are very important to understand the evolution of the Paleo-Tethyan Ocean.However,the Babu ophiolite is still disputed and the mafic and ultramafic rocks have been inferred to be part of the Emeishan large igneous province(LIP)by some researchers.In this paper,we present zircon U-Pb data on the metabasalts in | HUANG Hu DU Yuansheng YANG Jianghai YU Wenchao | 2017 | Acta Geologica Sinica(English Edition)2017,91,3: | 4 |
| 14 | Geochemistry of the Late Paleozoic cherts in the Youjiang Basin:Implications for the basin evolution显示文摘We analyzed the major and rare earth element compositions of siliceous deposits from the Upper Devonian Liujiang Formation,Lower Carboniferous Luzhai Formation,Lower-Middle Permian Sidazhai Formation and Tapi Formation,which are widely distributed as bedded cherts in the interplatform basinal successions of the Youjiang Basin.The Liujiang Formation and Luzhai Formation cherts generally have high Al/(Al+Fe+Mn) values(0.38-0.94) and are non-hydrothermal cherts.These cherts are generally characterized by moderately negative Ce anomalies and high Y/Ho values relatived to PAAS,indicating that the Youjiang Basin might have evolved into an open rift basin during the Late Devonian-Early Carboniferous.The Sidazhai Formation cherts from Ziyun generally have high Al/(Al+Fe+Mn) values(0.60-0.78),suggesting negligible contribution from a hydrothermal component.The Sidazhai Formation cherts from Hechi and the Tapi Formation cherts from Malipo generally have low Al/(Al+Fe+Mn) values(0.09-0.41),indicating an intense hydrothermal input.Relatived to the Sidazhai Formation cherts,the Tapi Formation cherts have higher Ce/Ce*values(0.68±0.19) and lower Y/Ho values(41.83±13.27),which may be affected by the terrigenous input from the Vietnam Block.The Sidazhai Formation cherts from Ziyun and Hechi exhibit negative Ce anomalies(0.43±0.12,0.33±0.17,respectively) with high Y/Ho values(57.44±16.20,46.02±4.27,respectively),resembling the geochemical characteristics of open-ocean basin cherts.These cherts were deposited on a passive continental margin adjacent to the Babu branch ocean,which may have contributed to upwelling.Detailed spatial studies on geochemical characteristics of the Late Paleozoic cherts can unravel the evolution of the Youjiang Basin. | Huang Hu Du Yuansheng Yang Jianghai Huang Hongwei Tao Ping Huang Zhiqiang Yu Wenchao Guo Hua | 2013 | Journal of Palaeogeography2013,2,4: | 4 |
| 15 | Excitation-emission matrix (EEM) fluorescence spectroscopy for characterization of organic matter in membrane bioreactors: Principles, methods and applications显示文摘The membrane bioreactor(MBR)technology is a rising star for wastewater treatment.The pollutant elimination and membrane fouling performances of MBRs are essentially related to the dissolved organic matter(DOM)in the system.Three-dimensional excitation-emission matrix(3D-EEM)fluorescence spectroscopy,a powerful tool for the rapid and sensitive characterization of DOM,has been extensively applied in MBR studies;however,only a limited portion of the EEM fingerprinting information was utilized.This paper revisits the principles and methods of fluorescence EEM,and reviews the recent progress in applying EEM to characterize DOM in MBR studies.We systematically introduced the information extracted from EEM by considering the fluorescence peak location/intensity,wavelength regional distribution,and spectral deconvolution(giving fluorescent component loadings/scores),and discussed how to use the information to interpret the chemical compositions,physiochemical properties,biological activities,membrane retention/fouling behaviors,and migration/transformation fates of DOM in MBR systems.In addition to conventional EEM indicators,novel fluorescent parameters are summarized for potential use,including quantum yield,Stokes shift,excited energy state,and fluorescence lifetime.The current limitations of EEM-based DOM characterization are also discussed,with possible measures proposed to improve applications in MBR monitoring. | Jinlan Yu Kang Xiao Wenchao Xue Yue-xiao Shen Jihua Tan Shuai Liang Yanfen Wang Xia Huang | 2020 | Frontiers of Environmental Science & Engineering2020,14,2: | 3 |
| 16 | Similar Time Series Retrieval Using Only Important Segments显示文摘Similar time series searching plays an important role in applications such as time series classification and outlier detection. We observe that different segment of a time series may have different significance, thus propose to assign different weight to each segment, and extract those segments with highest weights for distance computation. Since these segments are more representative, we can achieve high accuracy of similarity search with much lower computation overhead. The result of experiments on both real world and synthetic data sets demonstrates that we can achieve comparable or even higher accuracy while largely reduce the computation overhead, if we use only those important segments rather than the whole time series while performing similarity search. | GONG Xudong WANG Caimei XIONG Yan HUANG Wenchao | 2017 | Chinese Journal of Electronics2017,26,1: | 3 |
| 17 | A cynomolgus monkey with naturally occurring Parkinson’s disease显示文摘Evidence for the existence of monkeys with spontaneous Parkinson’s disease(PD)has been lacking.Here,we screened macaque colonies at the Kunming Primate Research Center(Association for Assessment and Accreditation of Laboratory Animal Care(AAALAC)accredited),Kunming Institute of Zoology,Chinese Academy of Sciences,which has a large population of monkeys(>2400),to identify naturally occurring PD monkeys. | Hao Li Ling-Yan Su Lixin Yang Min Li Qianjin Liu Zhenhui Li Yan Hu Hongwei Li Shihao Wu Wenchao Wang Yingzhou Hu Zhengbo Wang Joshua DRizak Baihui Huang Min Xu Jing Wu Long-Bao Lv Christoph W.Turck Yong Yin Yong-Gang Yao Bing Su Xintian Hu | 2021 | National Science Review2021,8,3: | 3 |
| 18 | In-situ growth of MAX phase coatings on carbonised wood and their terahertz shielding properties显示文摘Electromagnetic interference(EMI)shielding materials have received considerable attention in recent years.The EMI shielding effectiveness(SE)of materials depends on not only their composition but also their microstructures.Among various microstructure prototypes,porous structures provide the advantages of low density and high terahertz wave absorption.In this study,by using carbonised wood(CW)as a template,1-mm-thick MAX@CW composites(Ti2AlC@CW,V2A1C@CW,and Cr2AlC@CW)with a porous structure were fabricated through the molten salt method.The MAX@CW composites led to the formation of a conductive network and multilayer interface,which resulted in improved EMI SE.The average EMI SE values of the three MAX@CW composites were>45 dB in the frequency of 0.6-1.6 THz.Among the composites,V2A1C@CW exhibited the highest average EMI SE of 55 dB. | Jiaxuan HUANG Hujie WAN Mian LI Yiming ZHANG Jianfeng ZHU Xuelin LI Wenchao SHUI Yao LI Xiaomeng FAN Qiye WEN Xu XIAO Qing HUANG | 2021 | Journal of Advanced Ceramics2021,10,6: | 2 |
| 19 | Stable perovskite solar cells with efficiency of 22.6%via quinoxaline-based polymeric hole transport material显示文摘Poor stability of spiro-OMe TAD hole transport materials(HTMs)with dopant is a major obstacle for the commercialization of perovskite solar cells(pero-SCs).Herein,we demonstrate a series of quinoxaline-based D-A copolymers PBQ5,PBQ6 and PBQ10 as the dopant-free polymer HTMs for high performance pero-SCs.The D-A copolymers are composed of fluorothienyl benzodithiophene(BDTT)as D-unit,difluoroquinoxaline(DFQ)with different side chains as A-unit,and thiophene asπ-bridge,where the side chains on the DFQ unit are bi-alkyl for PBQ5,bi-alkyl-fluorothienyl for PBQ6,and alkoxyl for PBQ10.All the three copolymers are adopted as the dopant-free HTM in the pero-SCs.The planar n-i-p structured pero-SCs based on(FAPb I_(3))_(0.98)(MAPb Br_(3))_(0.02)with PBQ6 HTM demonstrated the high power conversion efficiency(PCE)of 22.6%with Vocof1.13 V and FF of 80.8%,which is benefitted from the suitable energy level and high hole mobility of PBQ6.The PCE of 22.6%is the highest efficiency reported in the n-i-p structured pero-SCs based on dopant-free D-A copolymer HTM.In addition,the peroSCs show significantly enhanced ambient,thermal and light-soaking stability compared with the devices with traditional spiroOMe TAD HTM. | Chenxing Lu Can Zhu Lei Meng Chenkai Sun Wenbin Lai Shucheng Qin Jinyuan Zhang Wenchao Huang Jiaqi Du Yiyang Wang Yongfang Li | 2021 | Science China Chemistry2021,64,11: | 2 |
| 20 | Stress dependence of the creep behaviors and mechanisms of a third-generation Ni-based single crystal superalloy显示文摘Elevated temperature creep behaviors at 1100℃ over a wide stress regime of 120-174 MPa of a thirdgeneration Ni-based single crystal superalloy were studied. With a reduced stress from 174 to 120 MPa, the creep life increased by a factor of 10.5, from 87 h to 907 h, presenting a strong stress dependence. A splitting phenomenon of the close-(about 100 nm) and sparse-(above 120 nm) spaced dislocation networks became more obvious with increasing stress. Simultaneously, ao<010> superdislocations with low mobil让ies were frequently observed under a lower stress to pass through γ precipitates by a combined slip and climb of two ao<110> superpartials or pure climb. However, ao<110> superdislocations with higher mobility were widely found under a higher stress, which directly sheared into y precipitates. Based on the calculated critical resolved shear stresses for various creep mechanisms, the favorable creep mechanism was systematically analyzed. Furthermore, combined with the microstructural evolutions during different creep stages, the dominant creep mechanism changed from the dislocation climbing to Orowan looping and precipitates shearing under a stress regime of 137-174MPa, while the dislocation dim bing mechanism was operative throughout the whole creep stage un der a stress of 120 MPa, resulting a superior creep performanee. | Quanzhao Yue Lin Liu Wenchao Yang Chuang He Dejian Sun Taiwen Huang Jun Zhang Hengzhi Fu | 2019 | Journal of Materials Science & Technology2019,35,5: | 2 |