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502篇 您的检索式:作者名="Wenqi"
    题名 作者 年代 出处 被引量
1Autophagy: a double-edged sword for neuronal survival after cerebral ischemia显示文摘Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether activation of autophagy increases or decreases the rate of neuronal death is still under debate. This review summarizes the potential role and possible signaling pathway of autophagy in neuronal survival after cerebral ischemia and proposes that autophagy has dual effects.Wenqi Chen Yinyi Sun Kangyong Liu Xiaojiang Sun 2014Neural Regeneration Research2014,9,12:57
23RISPR-P 2.0: An Improved CRISPR-Cas9 Too For Genome Editing in Plants显示文摘Hao Liu Yuduan Ding Yanqing Zhou Wenqi Jin Kabin Xie Ling-Ling Chen 2017Molecular Plant2017,10,3:32
3Simultaneous desulfurization and denitrification of sintering flue gas via composite absorbent显示文摘Experiments on simultaneous absorption of SO_2 and NO_X from sintering flue gas via a composite absorbent NaClO_2/NaClO were carried out. The effects of various operating parameters such as NaClO_2 concentration(ms), NaClO concentration(mp), molar ratio of NaClO_2/NaClO(M), solution temperature(TR), initial solution pH, gas flow(Vg) and inlet concentration of SO_2(CS) and NO(CN) on the removal efficiencies of SO_2 and NO were discussed. The optimal experimental conditions were determined to be initial solution pH = 6, TR=55 °C and M = 1.3 under which the average efficiencies of desulfurization and denitrification could reach99.7% and 90.8%, respectively. Moreover, according to the analysis of reaction products, it was found that adding NaClO to NaClO_2 aqueous solution is favorable for the generation of ClO_2 and Cl_2 which have significant effect on desulfurization and denitrification. Finally, engineering experiments were performed and obtained good results demonstrating that this method is practicable and promising.Jie Wang Wenqi Zhong 2016Chinese Journal of Chemical Engineering2016,24,8:27
4Recent progress in mass spectrometry proteomics for biomedical research显示文摘Proteins are the key players in many cellular processes. Their composition, trafficking, and interactions underlie the dynamic processes of life. Furthermore, diseases are frequently accompanied by malfunction of proteins at multiple levels. Understanding how biological processes are regulated at the protein level is critically important to understanding the molecular basis for diseases and often shed light on disease prevention, diagnosis, and treatment. With rapid advances in mass spectrometry(MS)instruments and experimental methodologies, MS-based proteomics has become a reliable and essential tool for elucidating biological processes at the protein level. Over the past decade, we have witnessed great expansion of knowledge of human diseases with the application of MS-based proteomic technologies, which has led to many exciting discoveries. Herein we review the recent progress in MS-based proteomics in biomedical research, including that in establishing disease-related proteomes and interactomes. We also discuss how this progress will benefit biomedical research and clinical diagnosis and treatment of disease.Xu Li Wenqi Wang Junjie Chen 2017Science China(Life Sciences)2017,60,10:24
5Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage显示文摘Berberine 被识别通过低密度脂蛋白(LDL ) 的正式就职在人和仓鼠降低浆液胆固醇水平在肝的房间的受体。在阻止动脉粥样硬化评估它的潜力,在在 apolipoprotein 电子 deficient 的动脉粥样硬化开发的 berberine 的效果(apoE ?/?) 老鼠被调查。在 apoE ?/ ?鼠标,在 vivo 导致的 berberine 泡沫房间形成和支持的动脉粥样硬化开发。berberine 导致的泡沫房间形成也在老鼠 RAW264.7 房间,以及在老鼠和人的主要巨噬细胞被观察。由导致 scavenger 受体 A (SR -- 一) 在巨噬细胞的表示, berberine 增加了修改 LDL (DiO-Ac-LDL ) 的举起。导致 Berberine 的 SR -- 表情也在动脉粥样硬化患者在 vivo 并且在房间在巨噬细胞泡沫房间被观察损害。在 RAW264.7 房间的分析显示 berberine 导致了 SR -- 由压制 PTEN 表示的表情,它导致了持续 Akt 激活。我们的结果建议那在减轻动脉粥样硬化评估减少胆固醇的混合物的潜力,它涉及动脉粥样硬化开发的房间上的效果例如巨噬细胞,应该也被考虑。泡沫房间形成的提升能抵销阴沉的浆液胆固醇的有益的效果。Ke Li Wenqi Yao Xiudan Zheng Kan Liao 2009Cell Research2009,19,8:18
6CFD-DEM simulation of spouting of corn-shaped particles显示文摘Three dimensionally coupled computational fluid dynamics (CFD) and discrete element method (DEM) were used to investigate the flow of corn-shaped particles in a cylindrical spouted bed with a conical base. The particle motion was modeled by the DEM, and the gas motion by the k-ε two-equation turbulent model. A two-way coupling numerical iterative scheme was used to incorporate the effects of gas-particle interactions in terms of momentum exchange. The corn-shaped particles were constructed by a multisphere method. Drag force, contact force, Saffman lift force, Magnus lift force, and gravitational force acting on each individual particle were considered in establishing the mathematical modeling. Calculations were carried out in a cylindrical spouted bed with an inside diameter of 200 mm, a height of 700 mm, and a conical base of 60 . Comparison of simulations with experiments showed the availability of the multi-sphere method in simulating spouting action with corn-shaped particles, but it depended strongly on the number and the arrangement of the spherical elements. Gas-solid flow patterns, pressure drop, particle velocity and particle concentration at various spouting gas velocity were discussed. The results showed that particle velocity reaches a maximum at the axis and then decreases gradually along the radial direction in the whole bed. Particle concentration increases along the radial direction in the spout region but decreases in the fountain region, while it is nearly constant in the annulus region. Increasing spouting gas velocity leads to larger pressure drop, remarkably increased speed of particle moving upward or downward, but decreased particle concentration.Bing Ren Wenqi Zhong Yu Chen Xi Chen Baosheng Jin Zhulin Yuan Yong Lu 2012Particuology2012,10,5:17
7Macropinocytosis contributes to the macrophage foam cell formation in RAW264.7 cells显示文摘在动脉粥样硬化发展的关键事件是由巨噬细胞和在 subendothelial 的泡沫房间的形成的类脂化合物举起动脉的空间。除由 scavenger 的修改低密度的脂蛋白(LDL ) 的举起以外调停受体的 endocytosis,巨噬细胞拥有组成的 macropinocytosis,它能够收起溶质的大数量。巨噬细胞泡沫房间形成能被在文化媒介增加浆液集中在 RAW264.7 房间导致。浆液导致的泡沫房间形成能被 phosphoinositide 3-kinase 禁止者, LY294002 或 wortmannin 堵住,它禁止了 macropinocytosis 然而并非调停受体的 endocytosis。进一步的分析显示 macropinocytosis 发生在充实 gangliosides 的膜区域。由没有影响 scavenger 的 -methylcyclodextrin-blocked macropinocytosis 的胆固醇弄空修改 LDL 的调停受体的 endocytosis。这些结果建议 macropinocytosis 可能是为在巨噬细胞的类脂化合物举起的重要机制之一。并且它做了重要贡献到类脂化合物累积和泡沫房间形成。Wenqi Yao Ke Li Kan Liao 2009Acta Biochimica et Biophysica Sinica2009,41,9:16
8Recent Progress Using High-throughput Sequencing Technologies in Plant Molecular Breeding显示文摘High-throughput sequencing is a revolutionary technological innovation in DNA sequencing.This technology has an ultra-low cost per base of sequencing and an overwhelmingly high data output.High-throughput sequencing has brought novel research methods and solutions to the research fields of genomics and post-genomics.Furthermore,this technology is leading to a new molecular breeding revolution that has landmark significance for scientific research and enables us to launch multi-level,multi-faceted,and multi-extent studies in the fields of crop genetics,genomics,and crop breeding.In this paper,we review progress in the application of high-throughput sequencing technologies to plant molecular breeding studies.Qiang Gao Guidong Yue Wenqi Li Junyi Wang Jiaohui Xu Ye Yin 2012Journal of Integrative Plant Biology2012,54,4:15
9Magnetoresistance enhancement and temperature stability of magnetoresistance in La_(1-x)(Sr_(1-y)Na_y)_xMnO_3显示文摘A series of the samples La_(1-x)(Sr_(1-y)Na_y)_xMnO_3(y=0.0,0.2,0.4,0.6,0.8,1.0) were prepared by the solid-state reaction method.Magnetoresistance enhancement and temperature stability of magnetoresistance in the system La_(1-x)(Sr_(1-y)Na_y)_xMnO_3 with unchanged Mn^(3+)/Mn^(4+) ratio through the doping of both monovalent and divalent elements at A site were studied through the measurements of X-ray diffraction(XRD) patterns,resistivity-temperature(ρ-T) curves and magnetoresistance-temperature(MR-T) curves.The results indicate that with the increase of Na doping amount,the peak value of MR increases,and it increases from 12.4% for y=0.2 to 50.6% for y=1.0 in the magnetic field B=0.8 T;ρ-T curves exhibit the double-peak phenomenon,which comes from the competition between the resistivity of surface phase and that of body phase;for the sample of y=0.8,MR increases slowly from 8.3% to 9.4% in the temperature range from 259 to 179 K,and MR is so stable in such a wide temperature range,which provides reference for the research on the temperature stability of MR.Wang, Guiying Yan, Guoqing Yang, Jie Wang, Wenqi Tang, Yonggang Song, Qixiang Zhang, Mingyu Peng, Zhensheng 2012Rare Metals2012,31,4:13
10Pediatric reference intervals in China(PRINCE):design and rationale for a large,multicenter collaborative cross-sectional study显示文摘There is a lack of accurate pediatric reference intervals(RIs) in China, with most commonly used RIs established without consideration of the effect of age and gender. The Pediatric Reference Intervals in China(PRINCE) project aims to establish and verify pediatric RIs for 31 common laboratory measurands.The project will be a large, multicenter cross-sectional study:14,490 healthy children and adolescents aged up to 19 years will be surveyed by 10 children's hospitals and one pediatric department of a university hospital. To evaluate the feasibility and efficiency of the study methods, 602 children were surveyed in the pilot phase of the PRINCE study in April 2017: it found that some measurands were distinctly age dependent and that there were differences between values for males and females. The results of the pilot study affirmed the necessity of the PRINCE project for Chinese pediatrics. The pilot also indicated potential difficulties in the full survey, e.g., difficulties in recruiting children aged under 3 years and insufficient collection of blood samples from infants. The operation of the PRINCE project has been modified based on the findings in the pilot study toward improving the validity of the PRINCE project and promoting its openness and transparency.Xin Ni Wenqi Song Xiaoxia Peng Ying Shen Yaguang Peng Qiliang Li Yan Wang Lixin Hu Yanying Cai Hong Shang Min Zhao Hong Jiang Yaoguo Huang Runqing Mu Wenxiang Chen Mingting Peng Chuanbao Zhang Jie Zeng Chenbin Li Hongling Yang Yongmei Jiang Jin Xu Guixia Li Hongbing Chen Yun Xiang Sancheng Cao Zhenxin Guo Dapeng Chen 2018Science Bulletin2018,63,24:12
11Low-loss metasurface optics down to the deep ultraviolet region显示文摘Shrinking conventional optical systems to chip-scale dimensions will benefit custom applications in imaging,displaying,sensing,spectroscopy,and metrology.Towards this goal,metasurfaces-planar arrays of subwavelength electromagnetic structures that collectively mimic the functionality of thicker conventional optical elements-have been exploited at frequencies ranging from the microwave range up to the visible range.Here,we demonstrate highperformance metasurface optical components that operate at ultraviolet wavelengths,including wavelengths down to the record-short deep ultraviolet range,and perform representative wavefront shaping functions,namely,highnumerical-aperture lensing,accelerating beam generation,and hologram projection.The constituent nanostructured elements of the metasurfaces are formed of hafnium oxide-a loss-less,high-refractive-index dielectric material deposited using low-temperature atomic layer deposition and patterned using high-aspect-ratio Damascene lithography.This study opens the way towards low-form factor,multifunctional ultraviolet nanophotonic platforms based on flat optical components,enabling diverse applications including lithography,imaging,spectroscopy,and quantum information processing.Cheng Zhang Shawn Divitt Qingbin Fan Wenqi Zhu Amit Agrawal Yanqing Lu Ting Xu Henri J.Lezec 2020Light(Science & Applications)2020,9,1:11
12Preparation of cross-linked magnetic chitosan with quaternary ammonium and its application for Cr(Ⅵ) and P(Ⅴ) removal显示文摘Pollutants that exist in anionic species are issues of concern in water treatment.Compared to cationic pollutants,the removal of anionic pollutants by adsorption is more difficult because most adsorbents carry predominantly negative charges in neutral and alkaline environments.In this study,a cross-linked chitosan derivative with quaternary ammonium and magnetic properties(QM-chitosan)was prepared and employed to remove chromium(VI)and phosphorus(V)(Cr(VI)and P(V))from aqueous environments.The QM-chitosan was characterized by Fourier transform infrared spectrometry(FT-IR),thermogravimetric analysis(TGA),energy dispersive X-ray(SEM-EDX)and zeta potential.Batch experiments show that QM-chitosan can effectively remove Cr(VI)and P(V),and the main mechanism was believed to be electrostatic interaction.A pseudosecond-order model was fitted to describe the kinetic processes of Cr(VI)and P(V)removal.The adsorption isotherms of both Cr(VI)and P(V)on the QM-chitosan were well fitted by the Langmuir isotherm equation.The saturated adsorption capacity of P(V)(2.783 mmol/g)was found to be higher than that of Cr(VI)(2.323 mmol/g),resulting from the size of the H2PO-4ions being smaller than that of the HCr O-4ions.However,the theoretical calculation and experimental results showed that QM-chitosan had a stronger affinity for Cr(VI)than P(V).The adsorption–desorption of the QM-chitosan was evaluated,and high regeneration rates were demonstrated.Wei Yao Pinhua Rao Irene M.C.Lo Wenqi Zhang Wenrui Zheng 2014Journal of Environmental Sciences2014,26,12:9
13Gold nanorods core/AgPt alloy nanodots shell: A novel potent antibacterial nanostructure显示文摘根据银 nanoparticles (Ag NP ) 的当前的问题以抗菌剂性能,我们与取向附生地作为一个潜在的抗菌剂代理人在金 nanorods (Au@PtAg NR ) 上种的 AgPt 合金 nanodots 设计了新奇 trimetallic 核心 / 壳 nanostructure。两 Escherichia coli (E。coli ) 并且葡萄球菌 aureus (S。aureus ) 被学习。抗菌剂活动展出明显的作文依赖。在在合金壳增加 Ag 部分直到 80% 以后,抗菌剂活动逐渐地增加,表明一个灵活方法调节这项活动。在 80% Ag,抗菌剂活动比纯 Ag 壳的好。改进抗菌剂能力主要由于点形态学在壳表面上源于银的高暴露。当为基于 Ag 的 nanomaterials 保留高化学的稳定性时,我们因此证明形成合金是改进抗菌剂活动的一个有效方法。而且,由于悦耳的局部性的表面 plasmonic 反应在在红外线附近(NIR ) 光谱区域,对把 lightsuch 用作杀死的 photothermal 和 phototriggered 银离子 releaseis 的抗菌剂活动的另外的控制期望。作为示范,高度提高了抗菌剂活动被利用 nanostructures 的 NIR photothermal 效果显示出。我们的结果显示如此的定制的 nanostructures 将在对细菌的未来战斗发现一个角色,包括 multidrug 抵抗的增加的严厉的挑战。Xiaona Hu Yuyun Zhao Zhijian Hu Aditya Saran Shuai Hou Tao Wen Wenqi Liu Yinglu Ji Xingyu Jiang Xiaochun Wu 2013Nano Research2013,6,11:9
14Research and Development of Supercritical Carbon Dioxide Coal-Fired Power Systems显示文摘Using supercritical carbon dioxide(S-CO2)Brayton cycle instead of the traditional steam Rankine cycle is a promising technique to enhance the coal-fired power generation efficiency.Researchers from all over the world are actively designing and exploring efficient S-CO2 coal-fired power plants in recent years with great efforts made to overcome the significant technical challenges in the cycle layouts of S-CO2 and its specific thermal integration with coal-fired heat resources.This paper provides a detailed review of the research progress on the coal-fired power generation using S-CO2 Brayton cycles.The basic knowledge of S-CO2 properties,the promising S-CO2 power cycles and the conceptual designs for S-CO2 coal-fired power plants are comprehensively summarized,with some key issues in the constructing process and the corresponding engineering solutions being emphatically discussed.Based on the current achievements,the overall technical and economic evaluations on the S-CO2 coal-fired power system are figured out.Furthermore,the specific integration applications of S-CO2 cycles with different coal firing devices and modes including pulverized coal combustion,circulating fluidized bed combustion,oxy-coal combustion,pressurized fluidized bed combustion,chemical looping combustion are discussed.Finally,the main challenges requiring further studies are highlighted.LI Zhaozhi LIU Xuejiao SHAO Yingjuan ZHONG Wenqi 2020Journal of Thermal Science2020,29,3:9
15A pure quasi-human algorithm for solving the cuboid packing problem显示文摘We excavate the wisdom from an old Chinese proverb 'gold corner, silver side and strawy void', and further improve it into 'maximum value in diamond cave' for solving the NP-hard cuboid packing problem. We extract, integrate and formalize the idea by west modern mathematical tools, and propose a pure quasi-human algorithm. The performance of the algorithm is evaluated on two sets of public benchmarks. For 100 strongly heterogeneous difficult benchmarks, experiments show an average packing utilization of 87.31%, which surpasses current best record reported in the literature by 1.83%. For 47 difficult benchmarks without orientation constraint, experiments show an average volume utilization of 92.05%, which improves current best record reported in the literature by 1.05%.HUANG WenQi HE Kun 2009Science in China(Series F)2009,52,1:8
16Prognostic value of programmed death.1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1.4N+M0 gastric adenocarcinoma显示文摘Background: Anti-programmed death-1/programmed death-ligand 1(PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of patients with gastric cancer to anti-PD-1/PD-L1 immunotherapy is controversial. Some studies suggested that intra-and inter-tumoral heterogeneity of PD-L1 expression might explain the controversy.This study aimed to analyze the expression of PD-L1, PD-L2, and PD-1 as well as CD8(+) T-cell density in primary tumors and lymph nodes from patients with stage T1-4 N+M0 gastric adenocarcinoma to explore the heterogeneity of PD-1 signaling pathway molecules.Methods: In primary tumors and metastatic as well as non-metastatic lymph nodes from patients with stage T1-4 N+M0 gastric adenocarcinoma, we detected PD-L1 and PD-L2 expression with immunohistochemistry. CD8(+)T-cell density in primary tumors and PD-1 expression on CD8(+)T cells were detected with immunofluorescence. Univariate analysis was used to determine the prognostic values of them. Cox proportional hazard regression model was used to identify independent risk factors that affect patients' overall survival and disease-free survival.Results: Among 119 eligible patients who had undergone surgical resection, the positive rate of PD-L1 was higher in metastatic lymph nodes than in primary tumors(45.4% vs. 38.7%, P = 0.005); the positive rate of PD-1 on CD8(+)T cells was significantly higher in primary tumors and metastatic lymph nodes than in tumor-free lymph nodes(both P < 0.001). The intensity of PD-1 expression on CD8(+) T cells in primary tumors and in metastatic lymph nodes were stronger than that in tumor-free lymph nodes from the same patient. Beside, the positive rate of PD-L2 did not show any differences between primary tumors and metastatic lymph nodes. In multivariate analysis, PD-L1 expression,PD-L2 expression, a low density of CD8(+) T cells in primary tumors, and PD-1 expression on CD8(+) T cells in primary tumors were associated with poor prognosis.Conclusion: The expression of PD-L1 is heterogeneous in primary tumors and in metastatic lymph nodes from patients with stageT1-4 N+M0 gastric adenocarcinoma, which might explain the inconsistent results in assessing the prognostic value of PD-L1 expression in previous studies.Yuan Gao Su Li Dazhi Xu Shangxiang Chen Yuchen Cai Wenqi Jiang Xinke Zhang Jin Sun Kefeng Wang Boyang Chang Fenghua Wang Minghuang Hong 2017Chinese Journal of Cancer2017,36,11:8
17Multifunctional metasurfaces enabled by simultaneous and independent control of phase and amplitude for orthogonal polarization states显示文摘Monochromatic light can be characterized by its three fun dame ntal properties:amplitude,phase,and polarization.In this work,we propose a versatile,transmission-mode all-dielectric metasurface platform that can independently manipulate the phase and amplitude for two orthogonal states of polarization in the visible frequency range.For proof-o仁concept experimental demonstration,various single-layer metasurfaces composed of subwavelength-spaced titanium-dioxide nanopillars are designed,fabricated,and characterized to exhibit the ability of polarization-switchable multidimensional light-field manipulation,including polarization-switchable grayscale nanoprinting,nonuniform cylindrical lensing,and complex-amplitude holography.We envision the metasurface platform dem on strated here to open new possibilities toward creating compact multifunctional optical devices for applications in polarization optics,information encoding,optical data storage,and security.Mingze Liu Wenqi Zhu Pengcheng Huo Lei Feng Maowen Song Cheng Zhang Lu Chen Henri JLezec Yanqing Lu Amit Agrawal Ting Xu 2021Light(Science & Applications)2021,10,6:8
18Virtual simulation analysis and verification of seed-filling mechanism for dipper hill-drop precision direct rice seeder显示文摘In order to improve the seeder’seed-filling ability of the dipper hill-drop precision direct rice seeder,and to meet the mechanization requirement of high speed operation,the self-designed seeder was taken as the objective to explore its seed-filling mechanism and the movement status of rice seed in seed box from the perspective of mechanics.The force models of seed-filling process by dipper were established,and the influential regularity of its rotation speed to compressive resistance of seed population was analyzed as well.The image processing Module-Clipping of discrete element simulation software EDEM was used in the virtual simulation analysis for the process of the seed filling into the dipper,and the velocity relation curve and the force changing curve between rotation speed and seeds were obtained.According to the virtual experiment,the composite filling force of seeds,i.e.the qualified rate on filled rice seed amounts was the largest when rotation speed was at 40 r/min.The performance test bed of seeder was used to verify the simulation results,in which the qualified rate on scooped rice seed amounts was taken as the index,and six rotation speeds of seed-filling dipper were also selected for analysis of seed-filling ability of the device.The results are as follows:with the increase of working speed,the qualified rate on filled rice seed amounts fluctuated with a trend of cosine curve,the largest value was 94.16%occurred when the rotation speed of seed-filling dipper was at 40 r/min.The variation trend of simulation value was approximately consistent with that of verification value.The study can provide a reference for the research and development of mechanical seeder.Wang Jinwu Zhou Wenqi Tian Liquan Li Shuwei Zhang Zhao 2017International Journal of Agricultural and Biological Engineering2017,10,6:7
19Elucidating Variations in Nitrogen Requirement According to Yield, Variety and Cropping System for Chinese Rice Production显示文摘Better understanding of the factors that influence crop nitrogen(N) requirement plays an important role in improving regional N recommendations for rice(Oryza sativa L.) production. We collected data from 1 280 plot-level measurements in different reaches of the Yangtze River, China to determine which factors contributed to variability in N requirement in rice. Yield, variety, and cropping system were significantly related to N requirement. The N requirement remained consistent at about 18.6 kg N Mg^(-1)grain as grain yield increased from 7 to 9 Mg ha^(-1), then decreased to 18.1, 16.9, and 15.9 kg N Mg^(-1)grain as yield increased to 9–10, 10–11, and > 11 Mg ha^(-1), respectively. The decreased requirement for N with increasing yield was attributable to declining N concentrations in grain and straw and increased harvest index. Super rice variety had lower N requirement(17.7 kg N Mg^(-1)grain) than ordinary inbred and hybrid varieties(18.5 and 18.3 kg N Mg^(-1)grain, respectively), which was a result of lower grain and straw N concentrations of super rice. The N requirements were 19.2, 17.8, and 17.5 kg N Mg^(-1)grain for early, middle, and late rice cropping systems, respectively. In conclusion, the rice N requirement was affected by multiple factors, including yield, variety, and cropping system, all of which should be considered when planning for optimal N management.ZHANG Yi CHEN Xinping MA Wenqi CUI Zhenling 2017Pedosphere2017,27,2:7
20Deep-learning-based ciphertext-only attack on optical double random phase encryption显示文摘Optical cryptanalysis is essential to the further investigation of more secure optical cryptosystems.Learning-based at-tack of optical encryption eliminates the need for the retrieval of random phase keys of optical encryption systems but it is limited for practical applications since it requires a large set of plaintext-ciphertext pairs for the cryptosystem to be at-tacked.Here,we propose a two-step deep learning strategy for ciphertext-only attack(COA)on the classical double ran-dom phase encryption(DRPE).Specifically,we construct a virtual DRPE system to gather the training data.Besides,we divide the inverse problem in COA into two more specific inverse problems and employ two deep neural networks(DNNs)to respectively learn the removal of speckle noise in the autocorrelation domain and the de-correlation operation to retrieve the plaintext image.With these two trained DNNs at hand,we show that the plaintext can be predicted in real-time from an unknown ciphertext alone.The proposed learning-based COA method dispenses with not only the retrieval of random phase keys but also the invasive data acquisition of plaintext-ciphertext pairs in the DPRE system.Numerical simulations and optical experiments demonstrate the feasibility and effectiveness of the proposed learning-based COA method.Meihua Liao Shanshan Zheng Shuixin Pan Dajiang Lu Wenqi He Guohai Situ Xiang Peng 2021Opto-Electronic Advances2021,4,5:7
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