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| 1 | Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review显示文摘Background:The coronavirus disease(COVID-19)has been identified as the cause of an outbreak of respiratory illness in Wuhan,Hubei Province,China beginning in December 2019.As of 31 January 2020,this epidemic had spread to 19 countries with 11791 confirmed cases,including 213 deaths.The World Health Organization has declared it a Public Health Emergency of International Concern.Methods:A scoping review was conducted following the methodological framework suggested by Arksey and O'Malley.In this scoping review,65 research articles published before 31 January 2020 were analyzed and discussed to better understand the epidemiology,causes,clinical diagnosis,prevention and control of this virus.The research domains,dates of publication,journal language,authors'affiliations,and methodological characteristics were included in the analysis.All the findings and statements in this review regarding the outbreak are based on published information as listed in the references.Results:Most of the publications were written using the English language(89.2%).The largest proportion of published articles were related to causes(38.5%)and a majority(67.7%)were published by Chinese scholars.Research articles initially focused on causes,but over time there was an increase of the articles related to prevention and control.Studies thus far have shown that the virus7 origination is in connection to a seafood market in Wuhan,but specific animal associations have not been confirmed.Reported symptoms include fever,cough,fatigue,pneumonia,headache,diarrhea,hemoptysis,and dyspnea.Preventive measures such as masks,hand hygiene practices,avoidance of public contact,case detection,contact tracing,and quarantines have been discussed as ways to reduce transmission.To date,no specific antiviral treatment has proven effective;hence,infected people primarily rely on symptomatic treatment and supportive care.Conclusions:There has been a rapid surge in research in response to the outbreak of COVID-19.During this early period,published research primarily explored the epidemiology,causes,clinical manifestation and diagnosis,as well as prevention and control of the novel coronavirus.Although these studies are relevant to control the current public emergency,more high-quality research is needed to provide valid and reliable ways to manage this kind of public health emergency in both the short-and long-term. | Sasmita Poudel Adhikari Sha Meng Yu-Ju Wu Yu-Ping Mao Rui-Xue Ye Qing-Zhi Wang Chang Sun Sean Sylvia Scott Rozelle Hein Raat Huan Zhou | 2020 | Infectious Diseases of Poverty2020，9，2： | 28 |
| 2 | 含氟牙膏对离体脱矿恒牙再矿化作用的实验研究显示文摘目的评价含氟牙膏促进离体脱矿恒牙再矿化的作用。方法选取和制作牙体硬度170KHN左右的16颗离体年轻脱矿恒牙标本,随机分成A、B两组(P>0.05)。A组用无氟Crest牙膏作再矿化处理,B组用含氟的Crest牙膏作再矿化处理,同时将A、B组标本浸泡于人唾液中。用微硬度测量仪测定并记录每个牙标本的硬度。结果A组脱矿牙的硬度平均值为151.9±38.3,而再矿化后牙齿的硬度平均值为143.4±18.8,两组比较P>0.05。B组脱矿牙的硬度平均值为160.1±16.5,而再矿化后牙齿的硬度平均值为200.5±21.3,两组比较P<0.05。再矿化后AB两组的硬度值比较P<0.001。结论含氟牙膏对离体脱矿恒牙有较明显的再矿化作用。 | 陈宏 丁熙 张秀华 ZHANG Wu LI Yi-min Sean S. LEE | 2008 | 口腔医学2008，28，10： | 7 |
| 3 | Therapeutic effect of Guijiajiao (Colla Carapacis et Plastri) on bone regeneration in rats and zebrafish显示文摘OBJECTIVE:To investigate the effect of Guijiajiao(Colla Carapacis et Plastri, CCP), the glue of tortoise shell, on bone regeneration in zebrafish and male Wistar rats.METHODS: In this study, we applied in vitro and in vivo models, tissue section analysis, and quantitative polymerase chain reaction to assess the effects of CCP on bone repair. MG-63 cells were used in alkaline phosphatase(ALP) activity and mineralization assays. Zebrafish and male Wistar rats were used to evaluate the effects of CCP on bone repair in vivo.RESULTS: A simple preparation of CCP promoted osteogenesis in vivo and in vitro, and promoted MG-63 cell proliferation as well as ALP activity and mineralization. In addition, CCP activated Akt and extracellular signaling-regulated kinase pathways and significantly increased the expression of ossification-related genes and proteins such as runt-related transcription factor-2, osteocalcin, and osteopontin. The in vivo results revealed promotion of osteogenesis by immersing zebrafish in CCP for 72 h.An oral dose of 1.25 g/kg CCP significantly improved skull defects in rats, which was accompanied by an increase in serum ALP levels.CONCLUSION: One of the ingredients of Guilu Erxianjiao(tortoise shell and deer horn formula) pro-vides a practical alternative therapy for bone regeneration. | Su Weiyang Feng Chienwei Tseng Chungchih Hung Hanchun Chen Zhicheng Lee Hsinpai Jean Yenhsuan Wu Shingyi Sean Wen Zhihong | 2018 | Journal of Traditional Chinese Medicine2018，38，2： | 3 |
| 4 | Incidents relating to the intra-hospital transfer of critically ill patients显示文摘 | Ursula Beckmann Donna M. Gillies Sean M. Berenholtz Albert W. Wu Peter Pronovost | 2004 | Intensive Care Medicine2004，，8： | 3 |
| 5 | DC field dependence of dielectric constant and loss factor of Al2O3-doped barium strontium titanate for application in phased array antennas显示文摘 | Long Wu Sean Wu Feng-Chih Chang Yu-Tang Shen Yih-Chien Chen | 2000 | Journal of Materials Science2000，，23： | 1 |
| 6 | Preferential Expression and Function of Voltage-Gated, O2-Sensitive K+ Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction: Ionic Diversity in Smooth Muscle Cells显示文摘 | Stephen L. Archer Xi-Chen Wu Bernard Thébaud Ali Nsair Sebastien Bonnet Ben Tyrrell M Sean McMurtry Kyoko Hashimoto Gwyneth Harry Evangelos D. Michelakis | 2004 | Circulation Research2004，，3： | 1 |
| 7 | Influence of sputtering pressure on physical structure of AlN films prepared on Y-128° LiNbO3 by rf magnetron sputtering显示文摘 | Wu Long Wu Sean Song Hongtie | 2001 | J Vac Sci Technol A2001，19，1： | 1 |
| 8 | The effect of Eu 3+ -activated InVO 4 phosphors prepared by sol–gel method显示文摘 | Yee-Shin Chang Zhao-Rong Shi Yeou-Yih Tsai Sean Wu Hao-Long Chen | 2010 | Optical Materials2010，，3： | 1 |
| 9 | Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor beta signaling显示文摘 | Susann Weissmueller Eusebio Manchado Michael Saborowski John P. Morris Elvin Wagenblast Carrie A. Davis Sung-Hwan Moon Neil T. Pfister Darjus F. Tschaharganeh Thomas Kitzing Daniela Aust Elke K. Markert Jianmin Wu Sean M. Grimmond Christian Pilarsky Carol | 2014 | Cell2014，，： | 1 |
| 10 | Noise analysis of automotive alternators显示文摘 | Sean F Wu Eugene Rivin and Michael Disalvo | 1999 | SAE1999，，： | 1 |
| 11 | Meta-Analysis of Stem Cell Therapy in Chronic Ischemic Cardiomyopathy显示文摘 | Jagdesh Kandala Gaurav A. Upadhyay Evgeny Pokushalov Sean Wu Douglas E. Drachman Jagmeet P. Singh | 2013 | The American Journal of Cardiology2013，，2： | 1 |
| 12 | Effect of H2 on the etch profile of InP/InGaAsP alloys in Cl2/Ar/H2 inductively coupled plasma reactive ion etching chemistries for photonic device fabrication 显示文摘 | Sean L Rommel Jae- Hyung Jang Wu Lu | 2002 | J Vac Sci Technol2002，20，4： | 1 |
| 13 | 环境光和邻牙对前牙接触式测色仪测色结果的影响显示文摘目的探讨外源性环境光和邻牙对接触式测色仪测量牙齿颜色结果的影响。方法将10颗离体上颌中切牙固定,MI-150光源从牙齿的唇面(切缘朝下)3点钟和12点钟上方45°入射,入射强度分别为0、50、75、100、125、150W,在有邻牙和无邻牙时分别测量10颗离体中切牙中1/3正中点的CIEL﹡a﹡b﹡值,测量结果采用SPSS11.5软件进行统计分析。结果不同强度和方向的入射光及邻牙存在与否对颜色测量结果均没有明显影响(P>0.05)。结论环境光源和邻牙对接触式测色仪的测色结果没有影响,临床上在牙椅外源辅助灯光下可以采用接触式测色仪直接测色。 | 王思钱 Sean S. Lee Wu Zhang Yiming Li 麻健丰 | 2007 | 华西口腔医学杂志2007，25，5： | 1 |
| 14 | Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo显示文摘 | Patric Glynn Hassan Musa Xiangqiong Wu Sathya D. Unudurthi Sean Little Lan Qian Patrick J. Wright Przemyslaw B. Radwanski Sandor Gyorke Peter J. Mohler Thomas J. Hund | 2015 | Circulation2015，，7： | 1 |
| 15 | Developmental Origin of a Bipotential Myocardial and Smooth Muscle Cell Precursor in the Mammalian Heart显示文摘 | Sean M. Wu Yuko Fujiwara Susan M. Cibulsky David E. Clapham Ching-ling Lien Thomas M. Schultheiss Stuart H. Orkin | 2006 | Cell2006，，6： | 1 |
| 16 | DC field dependence of dielectric constant and loss factor of Al2O3-doped barium strontium titanate for application in phased array antennas显示文摘 | Long Wu Sean Wu Feng-Chih Chang Yu-Tang Shen Yih-Chien Chen | 2000 | Journal of Materials Science2000，，23： | 1 |
| 17 | metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters显示文摘 | Wu Dongying Sean C Daugherty Susan E Van Aken | | 0，，06： | 1 |
| 18 | The impedance-matchingdesign and simulation on high power elctro-acoustical transducer 显示文摘 | Chen Yeong-Chin Wu Sean Chen Ping-Cheng | 2004 | Sensors and Actuators : Physical2004，115，1： | 1 |
| 19 | Effects of small additions of Ag, Al, and Ga on the structure and properties of the Sn-9Zn eutectic alloy 显示文摘 | Chen K I Cheng S C Wu Sean | 2006 | Journal of Alloys and Compounds2006，416，12： | 1 |
| 20 | IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program显示文摘 | Sean E. Doyle Sagar A. Vaidya Ryan O’Connell Hajir Dadgostar Paul W. Dempsey Ting-Ting Wu Govinda Rao Ren Sun Margaret E. Haberland Robert L. Modlin Genhong Cheng | 2002 | Immunity2002，，3： | 1 |
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