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| 1 | Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease显示文摘 | Tang B Xiong H Sun P Zhang Y Wang D Hu Z Zhu Z Ma H Pan Q Xia JH Xia K Zhang Z | 2006 | 中国生物学文摘2006，20，8： | 30 |
| 2 | Association of elevated hs-CRP and multiple infarctions with outcomes of minor stroke or TIA: subgroup analysis of CHANCE randomised clinical trial显示文摘Background and purpose The relationship of high-sensitive C-reactive protein(hs-CRP)levels and infarction numbers with the prognosis of stroke is uncertain.This study evaluated the association of different hs-CRP levels and infarction numbers with the prognosis of acute minor ischaemic stroke or transient ischaemic attack(TIA).Methods A subset of 807 patients with both hs-CRP measurement and baseline MRI was included from the Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events trial.The primary efficacy outcome was the occurrence of an ischaemic stroke at the 1-year follow-up.Infarction numbers were classified as multiple acute infarctions(MAIs),single acute infarction and no acute infarction(NAI).The association between different hs-CRP levels with different infarction numbers and the risk of any outcome was analysed using multivariable Cox regression models.Results Among the 807 patients,84(10.4%)patients had a recurrent ischaemic stroke within 1 year.After adjustment for conventional confounding factors,patients with both elevated hs-CRP levels and MAIs were associated with approximately 4.7-fold of risk of ischaemic stroke within 1 year(16.7% vs 3.5%,HR 4.68,95% CI 1.54 to 14.23,p=0.007),compared with those with non-elevated hs-CRP levels and NAI.Similar results were observed for the composite events.Conclusions Combined elevated hs-CRP levels and MAIs may increase 1-year stroke risk stratification efficiency in patients with minor ischaemic stroke or TIA compared with using those markers alone,which indicated that the combination of inflammatory and imaging markers might improve the effectiveness of risk stratification concerning minor ischaemic stroke or TIA. | Guangyao Wang Jing Jing Jiejie Li Yuesong Pan Hongyi Yan Xia Meng Xingquan Zhao Liping Liu Hao Li David Z Wang Yongjun Wang Yilong Wang | 2021 | Stroke & Vascular Neurology2021，6，1： | 11 |
| 3 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 4 | Magnetic and transport properties in polycrystalline La2/3Ca1/3MnO3 显示文摘 | Yuan S L Zhao A Y Xia Z C | 2003 | Solid State Commun2003，125，： | 2 |
| 5 | Effect of solution composition and electrochemical potential on stress corrosion cracking of X-52 pipeline steel 显示文摘 | Rebak R B Xia Z Safruddin R | 1996 | Corrosion1996，52，5： | 2 |
| 6 | Natural Convective Boiling in Vertical Rectangular Narrow Channels 显示文摘 | Xia C Hu W Guo Z Y | 1996 | Experimental Thermal and Fluid Science1996，12，： | 2 |
| 7 | Chimeric calcium/calmodulin-dependent protein kinase in tobacco: differential regulation by calmodulin isoforms显示文摘 | LIU Z XIA M POOVAIAH B W | 1998 | Plant Molecular Biology1998，38，： | 1 |
| 8 | Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease显示文摘 | Xia Z Gu J Ansley D M | 2003 | J Thorac Cardiovasc Surg2003，126，： | 1 |
| 9 | Effects of Electric Field on the Electronic Structure and Optical Properties of Quantum Rods with Wurtzite Structure 显示文摘 | LI X Z XIA J B | 2003 | Phys Rev B2003，68，16： | 1 |
| 10 | 8-Hydroxyquinoline-chloroform single drop microextraction and electrothermal vaporization ICP-MS for the fractionation of aluminium in natural waters and drinks显示文摘 | Xia L B Hu B Jiang Z C | 2005 | Journal of Analytical Atomic Spectrometry2005，20，5： | 1 |
| 11 | Wave-induced mixing in the Yellow Sea 显示文摘 | YANG Y Z QIAO F L XIA C S | 2004 | Chin J Oceano Limnol2004，22，3： | 1 |
| 12 | Layered double hydroxides as supports for intercalation and sustained release of antihypertensive drugs 显示文摘 | XIA S J NI Z M XU Q | 2008 | J Solid State Chem2008，181，： | 1 |
| 13 | Electrical Properties of Gado-linium-Europium Ziroonate Ceramics显示文摘 | Xia X L Ouyang J H Liu Z G | 2010 | Journal of American Ceramic Society2010，93，4： | 1 |
| 14 | DAMBE: software package for data analysis in molecular biology and evolution显示文摘 | Xia X Xie Z | 2001 | Journal of Heredity2001，92，4： | 1 |
| 15 | Oscillation of second order neutral differential equations显示文摘 | Xia Y and Xu Z | 2006 | Southeast Asia Ball Math2006，，30： | 1 |
| 16 | Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis 显示文摘 | Xia Z Dickens M Raingeaud J | 1995 | Scienee1995，270，5240： | 1 |
| 17 | Assessment of protoxin composition of Bacillus thuringiensis strains by use of polyacrylamide gel block and mass spectrometry显示文摘 | Fu Z J Sun Y J Xia L Q | 2008 | Applied Microbiology and Biotechnology2008，79，5： | 1 |
| 18 | An Adaptive Adjusting Mechanism for Agent Distributed Blackboard Architecture显示文摘 | Jiang Y C Xia Z Y | 2005 | Microprocessors and Microsystems2005，29，1： | 1 |
| 19 | QSAR study on N-containing corrosion inhibitors:Quantum chemical approach assisted by topological index显示文摘 | S G Zhang W Lei M Z Xia | 2005 | Journal of Molecular Structure:THEOCHEM2005，732，： | 1 |
| 20 | Opposing effects of ERK and JNK- p38 MAP kinse on apoptosis 显示文摘 | Xia Z Dickens M Raingeaud J | 1995 | Science1995，270，24： | 1 |
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