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| 1 | Evaluation of a 3dVAR system for the South China Sea显示文摘The authors evaluate a three-dimensional variational (3dVAR) system for the South China Sea (SCS) in this study. The assimilation method applied in the system takes into consideration error correlation along each ground track and uses recursive lter for optimiza- tion. Data from three R/V cruises during the spring and summer of 1998 and the summer of 2000 are used to evaluate the system. The root-mean-square error and bias are reduced signi cantly and when the altimeter data are assimilated, the distribution of the error is much closer to the Gaussian distribution. Precipitation and river discharge in the southwestern SCS are reproduced, and the variability of sea surface height is e ciently transferred to the subsurface. The 3dVAR system performs well for each of the three cruises, suggesting that it is steady for routine usage. | Xianjun Xiao Dongxiao Wang Changxiang Yan Jiang Zhu | 2008 | Progress in Natural Science:Materials International2008，18，5： | 19 |
| 2 | The assimilation experimentin the southwestern South China Sea in summer 2000显示文摘We performed an assimilation experiment of the southern South China Sea in summer 2000, and the altimeter data were assimilated into Princeton Ocean Model (POM). The result was evaluated with the in situ data. There were obvious improvements of the currents in the southern South China Sea, and the modeling uncertainty coming from the error of wind stress forcing was reduced. This experiment provides us a new idea about improving the modeling of the ocean currents. | XIAO Xianjun WANG Dongxiao XU Jianjun | 2006 | Chinese Science Bulletin2006，51，B12： | 13 |
| 3 | Progress of regional oceanography study associated with western boundary current in the South China Sea显示文摘Recent progress of physical oceanography in the South China Sea (SCS) associated with the western boundary current (WBC) and eddies is reviewed in this paper. It includes Argo observations of the WBC, eddy detection in the WBC based on satellite images, cross-continental shelf exchange in the WBC, eddy-current interaction, interannual variability of the WBC, air-sea interaction, the SCS throughflow (SCSTF), among others. The WBC in the SCS is strong, and its structure, variability and dynamic processes on seasonal and interannual time scales are yet to be fully understood. In this paper, we summarize progresses on the variability of the WBC, eddy-current interaction, air-sea interaction, and the SCSTF achieved in the past few years. Firstly, using the drifting buoy observations, we point out that the WBC becomes stronger and narrower after it reaches the central Vietnam coast. The possible mechanisms influencing the ocean circulation in the northern SCS are discussed, and the dynamic mechanisms that induce the countercurrent in the region of northern branch of WBC in winter are also studied quantitatively using momentum balance. The geostropic component of the WBC was diagnosed using the ship observation along 18°N, and we found that the WBC changed significantly on interannual time scale. Secondly, using the ship observations, two anti-cyclonic eddies in the winter of 2003/2004 in the northern SCS, and three anti-cyclonic eddies in the summer of 2007 along 18°N were studied. The results show that the two anti-cyclonic eddies can propagate southwestward along the continental shelf at the speed of first Rossby wave (~0.1 ms-1 ) in winter, and the interaction between the three anti-cyclonic eddies in summer and the WBC in the SCS is preliminarily revealed. Eddies on the continental shelf of northern SCS propagated southeastward with a maximum speed of 0.09 ms-1 , and those to the east of Vietnam coast had the largest kinetic energy, both of which imply strong interaction between eddy activity and WBC in the SCS. Thirdly, strong intraseasonal variability (ISV) of sea surface temperature (SST) near the WBC regions was found, and the ISV signal of SST in winter weakens the ISV signal of latent heat flux by 20%. Fourthly, the long-term change of SCSTF volume transport and its connection with the ocean circulation in the Pacific were discussed. | WANG DongXiao LIU QinYan XIE Qiang HE ZhiGang ZHUANG Wei SHU YeQiang XIAO XianJun HONG Bo WU XiangYu SUI DanDan | 2013 | Chinese Science Bulletin2013，58，11： | 10 |
| 4 | Preliminary results of a new global ocean reanalysis显示文摘Using a new global ocean reanalysis of the second generation Global Ocean Data Assimilation System of the Beijing Climate Center(BCC_GODAS2.0) spanning the period 1990-2009,we firstly quantify the accuracy of BCC_GODAS2.0 in representing the temperature and salinity by comparing with OISST and SODA data.The results show that the assimilation system may effectively improve the estimations of temperature and salinity by assimilating all kinds of observations,especially in the equatorial eastern Pacific.Moreover,the root mean square errors of monthly temperature and salinity are respectively reduced by 0.53℃ and 0.28 psu,compared with the model control simulation results.Then,the applicability of this ocean reanalysis for sea surface temperature(SST) anomaly variability in the tropical Pacific is evaluated with the observational HadISST data.The NINO3 index of the new reanalysis shows a good agreement with that of HadISST,with a correlation of 93.6%.Variations in SST from BCC_GODAS2.0 are similar to those obtained from HadISST data along the equator,showing the major large zonal-scale features such as the strong magnitude of seasonal cycle.The amplitude of SST anomaly standard deviation in the equatorial eastern Pacific is also closer to observations(HadISST) than NCEP GODAS does.Besides,the first two leading empirical orthogonal function(EOF) modes of the monthly SST anomalies over the tropical Pacific region are explored.The EOF1 pattern of BCC_GODAS2.0 captures a traditional El Ni o pattern,which improves magnitudes of the positive SST anomaly in the cold tongue of the eastern Pacific.The EOF2 pattern exhibits a El Ni o Modoki pattern.Comparatively,the EOF2 pattern of BCC_GODAS2.0 extends more strongly toward the subtropics.It also overcomes the problem that negative loadings are confined in the narrow equatorial eastern Pacific.Consequently,the magnitude and spatial distribution of the leading EOF patterns of BCC_GODAS2.0 are well consistent with those of HadISST. | WANG DongXiao QIN YingHao XIAO XianJun ZHANG ZuQiang WU FengMin | 2012 | Chinese Science Bulletin2012，57，26： | 4 |
| 5 | Applying accurate gradients of seismic wave reflection coefficients (SWRC) to the inversion of seismic wave velocities显示文摘Through solving the Zoeppritz's partial derivative equations, we have obtained accurate partial derivatives of reflected coefficients of seismic wave with respect to Pand S-wave velocities.With those partial derivatives, a multi-angle inversion is developed for seismic wave velocities.Numerical examples of different formation models show that if the number of iterations goes over 10, the relative error of inversion results is less than 1%, whether or not there is interference among the reflection waves.When we only have the reflected seismograms of P-wave, and only invert for velocities of P-wave, the multi-angle inversion is able to obtain a high computation precision.When we have the reflected seismograms of both P-wave and VS-wave, and simultaneously invert for the velocities of P-wave and VS-wave, the computation precisions of VS-wave velocities improves gradually with the increase of the number of angles, but the computation precision of P-wave velocities becomes worse.No matter whether the reflected seismic waves from the different reflection interface are coherent or non-coherent, this method is able to achieve a higher computation precision.Because it is based on the accurate solution of the gradient of SWRCs without any additional restriction, the multi-angle inversion method can be applied to seismic inversion of total angles.By removing the difficulties caused by simplified Zoeppritz formulas that the conventional AVO technology struggles with, the multiangle inversion method extended the application range of AVO technology and improved the computation precision and speed of inversion of seismic wave velocities. | LIU FuPing MENG XianJun XIAO JiaQi WANG YuMei SHEN GuoQiang | 2012 | Science China Earth Sciences2012，55，12： | 3 |
| 6 | Impacts of a wind stress and a buoyancy flux on the seasonal variation of mixing layer depth in the South China Sea显示文摘The seasonal variation of mixing layer depth(MLD) in the ocean is determined by a wind stress and a buoyance flux.A South China Sea(SCS) ocean data assimilation system is used to analyze the seasonal cycle of its MLD.It is found that the variability of MLD in the SCS is shallow in summer and deep in winter,as is the case in general.Owing to local atmosphere forcing and ocean dynamics,the seasonal variability shows a regional characteristic in the SCS.In the northern SCS,the MLD is shallow in summer and deep in winter,affected coherently by the wind stress and the buoyance flux.The variation of MLD in the west is close to that in the central SCS,influenced by the advection of strong western boundary currents.The eastern SCS presents an annual cycle,which is deep in summer and shallow in winter,primarily impacted by a heat flux on the air-sea interface.So regional characteristic needs to be cared in the analysis about the MLD of SCS. | XIAO Xianjun WANG Dongxiao ZHOU Wen ZHANG Zuqiang QIN Yinghao HE Na ZENG Lili | 2013 | Acta Oceanologica Sinica2013，32，9： | 3 |
| 7 | Myelin Deficits Caused by Olig2 Deficiency Lead to Cognitive Dysfunction and Increase Vulnerability to Social Withdrawal in Adult Mice显示文摘Oligodendrocyte (OL) and myelin development are crucial for network integration and are associated with higher brain functions. Accumulating evidence has demonstrated structural and functional impairment of OLs and myelin in serious mental illnesses. However, whether these deficits contribute to the brain dysfunction or pathogenesis of such diseases still lacks direct evidence. In this study, we conditionally deleted Olig2 in oligodendroglial lineage cells (Olig2 cKO) and screened the behavioral changes in adult mice. We found that Olig2 ablation impaired myelin development, which further resulted in severe hypomyelination in the anterior cingulate cortex. Strikingly, Olig2 cKO mice exhibited an anxious phenotype, aberrant responses to stress, and cognitive deficits. Moreover, Olig2 cKO mice showed increased vulnerability to social avoidance under the mild stress of social isolation. Together,these results indicate that developmental deficits in OL and myelin lead to cognitive impairment and increase the risk of phenotypes reminiscent of mental illnesses. | Xianjun Chen Fei Wang Jingli Gan Zhonghua Zhang Xuejun Liang Tao Li Nanxin Huang Xiaofeng Zhao Feng Mei Lan Xiao | 2020 | Neuroscience Bulletin2020，36，4： | 3 |
| 8 | Cancer statistics: Current diagnosis and treatment of pancreatic cancer in Shanghai, China显示文摘 | Jiang Long Guo-pei Luo Zhi-wen Xiao Zu-qiang Liu Meng Guo Liang Liu Chen Liu Jin Xu Yu-tang Gao Ying Zheng Chunxiao Wu Quan-xing Ni Min Li Xianjun Yu | 2014 | Cancer Letters2014，，： | 2 |
| 9 | The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis显示文摘The endoplasmic reticulum(ER) membrane protein complex(EMC) regulates the synthesis and quality control of membrane proteins with multiple transmembrane domains. One of the membrane spanning subunits, EMC3, is a core member of the EMC complex that provides essential hydrophilic vestibule for substrate insertion. Here, we show that the EMC subunit Emc3 plays critical roles in the retinal vascular angiogenesis by regulating Norrin/Wnt signaling. Postnatal endothelial cell(EC)-specific deletion of Emc3 led to retarded retinal vascular development with a hyperpruned vascular network, the appearance of bluntended, aneurysm-like tip endothelial cells(ECs) with reduced numbers of filopodia and leakage of erythrocytes at the vascular front. Diminished tube formation and cell proliferation were also observed in EMC3 depleted human retinal endothelial cells(HRECs). We then discovered a critical role for EMC3 in expression of FZD4 receptor of β-catenin signaling using RNA sequencing, real-time quantitative PCR(RT-q PCR) and luciferase reporter assay. Moreover, augmentation of Wnt activity via lithium chloride(Li Cl) treatment remarkably enhanced β-catenin signaling and cell proliferation of HRECs. Additionally, Li Cl partially reversed the angiogenesis defects in Emc3-c KO mice. Our data reveal that Emc3 plays essential roles in angiogenesis through direct control of FZD4 expression and Norrin/β-catenin signaling. | Mu Yang Shujin Li Wenjing Liu† Xiao Li Yunqi He Yeming Yang Kuanxiang Sun Lin Zhang Wanli Tian Lixin Duan Huafu Chen Dezhong Yao Zhenglin Yang Xianjun Zhu | 2021 | Science China(Life Sciences)2021，64，11： | 2 |
| 10 | Hydrogen-rich gas from catalytic steam gasification of municipal solid waste (MSW): influence of catalyst and temperature on yield and product composition 显示文摘 | He Maoyun Hu Zhiquan Xiao Bo Li Jianfen Guo Xianjun Luo Siyi Yang Fan Feng Yu Yang Guangjun Liu Shiming | 2009 | International Journal of Hydrogen Energy2009，34，1： | 1 |
| 11 | NaOH and Ba(OH)_2 Compound Catalyzed PhenolResorcinol-Formaldehyde Copolycondensation Resin Adhesive for Recombined Bamboo显示文摘In order to reduce the curing temperature, shorten the curing time of phenol-formaldehyde(PF) resin adhesive, and ensure the good water-solubility, NaOH and Ba(OH)_2 were used as compound catalysts. The influences of the adding time of Ba(OH)_2, the adding amount of NaOH, Ba(OH)_2 and resorcinol on the properties of adhesives were studied. The properties of NaOH catalyzed phenol-formaldehyde(PF) adhesive, NaOH and Ba(OH)_2 compound catalyzed PF adhesive, NaOH and Ba(OH)_2 compound catalyzed phenol-resorcinol-formaldehyde(PRF) adhesive, and the prepared recombinant bamboo with three kinds of adhesives were compared. The experimental results show that NaOH and Ba(OH)_2 compound catalyst not only shortens the curing time of PF adhesive, but also guarantees the suitable water solubility of adhesive. After copolycondensation with resorcinol, the curing time of adhesive is further shortened, the water solubility is improved obviously, and the highest bonding strength is obtained. Infrared spectrum analysis shows that the reaction activity point of NaOH and Ba(OH)_2 compound catalyzed PRF adhesive will increase, so that both the curing temperature and curing enthalpy decrease. | 左迎峰 LIU Wenjie XIAO Junhua LI Xianjun ZHAO Xing 吴义强 | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，2： | 1 |
| 12 | Gasification characteristics of biomass micron fuel (BMF) : Study on steam gasification for hydrogen-rich gas products 显示文摘 | Guo Xianjun Xiao Bo Hu Zhiquan | 2008 | Fresenius environmental bulletin2008，17，5： | 1 |
| 13 | The Goos-Hnchen shift of wide-angle seismic reflection wave显示文摘The partial derivative equations of Zoeppritz equations are established and the derivatives of each matrix entry with respect to wave vectors are derived in this paper.By solving the partial derivative equations we obtained the partial derivatives of seismic wave reflection coefficients with respect to wave vectors,and computed the Goos-Hnchen shift for reflected P-and VS-waves.By plotting the curves of Goos-Hnchen shift,we gained some new insight into the lateral shift of seismic reflection wave.The lateral shifts are very large for glancing wave or the wave of the incidence angle near the critical angle,meaning that the seismic wave propagates a long distance along the reflection interface before returning to the first medium.For the reflection waves of incidence angles away from the critical angle,the lateral shift is in the same order of magnitude as the wavelength.The lateral shift varies significantly with different reflection interfaces.For example,the reflected P-wave has a negative shift at the reflection interface between mudstone and sandstone.The reflected VS-wave has a large lateral shift at or near the critical angle.The lateral shift of the reflected VS-wave tends to be zero when the incidence angle approaches 90°.These observations suggest that Goos-Hnchen effect has a great influence on the reflection wave of wide-angles.The correction for the error caused by Goos-Hnchen effect,therefore,should be made before seismic data processing,such as the depth migration and the normal-moveout correction.With the theoretical foundation established in this paper,we can further study the correction of Goos-Hnchen effect for the reflection wave of large incidence angle. | LIU FuPing MENG XianJun XIAO JiaQi WANG AnLing YANG ChangChun | 2012 | Science China Earth Sciences2012，55，5： | 1 |
| 14 | Hydrogen-rich gas from catalytic steam gasification of biomass in a asf fixed bed reactor: Influence of particle size on gasification performance显示文摘 | Luo Siyi Xiao Bo Guo Xianjun | 2009 | International Journal of Hydrogen Energy2009，34，3： | 1 |
| 15 | Syngas production from pyrolysis of municipal solid waste (MSW) with dolomite as downstream catalysts显示文摘 | Maoyun He Bo Xiao Shiming Liu Zhiquan Hu Xianjun Guo Siyi Luo Fan Yang | 2010 | Journal of Analytical and Applied Pyrolysis2010，，2： | 1 |
| 16 | Blood Neutrophil–Lymphocyte Ratio Predicts Survival in Patients with Advanced Pancreatic Cancer Treated with Chemotherapy显示文摘 | Guopei Luo Meng Guo Zuqiang Liu Zhiwen Xiao Kaizhou Jin Jiang Long Liang Liu Chen Liu Jin Xu Quanxing Ni Xianjun Yu | 2015 | Annals of Surgical Oncology2015，，： | 1 |
| 17 | Gasifica- micron fuel (BMF)-study on steam gasification for hydrogen-rich gas products 显示文摘 | Guo Xianjun Xiao Bo tion characteristics of biomass Hu Zhiquan | 2008 | Frese- nius Environmental Bulletin2008，17，5： | 1 |
| 18 | Hydrogen-rich gas from catalytic steam gasification of biomass in a fixed bed reactor: influence of particle size on gasification performance 显示文摘 | LUO Siyi XIAO Bo GUO Xianjun | 2009 | International Journal of Hydrogen Energy2009，34，3： | 1 |
| 19 | Molecular Mechanism Underlying Lymphatic Metastasis in Pancreatic Cancer显示文摘 | Zhiwen Xiao Guopei Luo Chen Liu Chuntao Wu Liang Liu Zuqiang Liu Quanxing Ni Jiang Long Xianjun Yu Sonshin Takao | 2014 | BioMed Research International2014，，： | 1 |
| 20 | Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy显示文摘Familial exudative vitreoretinopathy(FEVR),an inherited eye disease,is characterized by abnormal retinal vascular development,such as neovascularization,vitreous hemorrhage,exudation,and retinal detachment(Criswick and Schepens,1969;Robitaille et al.,2002).FEVR is inherited as autosomal dominant,autosomal recessive,and X-linked patterns(de Crecchio et al.,1998). | Shujin Li Mu Yang Yunqi He Xiaoyan Jiang Rulian Zhao Wenjing Liu Lulin Huang Yi Shi Xiao Li Kuanxiang Sun Yeming Yang Periasamy Sundaresan Peiquan Zhao Zhenglin Yang Xianjun Zhu | 2022 | Journal of Genetics and Genomics2022，49，6： | 1 |
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