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| 1 | Base-Editing-Mediated Artificial Evolution of OsALS1 In Planta to Develop Novel Herbicide-Tolerant Rice Germplasms显示文摘Recently developed CRISPR-mediated base editors,which enable the generation of num erous nucleotide changes in target genomic regions,have been widely adopted for gene correction and generation of crop germ plasms containing im portant gain-of-function genetic variations.How ever,to engineer target genes with unknown functional SNPs remains challenging.To address this issue,we present here abase-e diting-mediated gene evolution(BEMGE)m ethod,employing both Cas9n-based cytosine and adenine base editors as well as a single-guide RNA(sgRNA)library tiling the full-length coding region,for developing novel rice germ plasm swith mutations in any endogenous gene.To this end,OsALS1 was artificially evolved in rice cells using BEMGE through both Agrobacterium-mediated and particle-bom bardment-mediated transform ation.Four different types of amino acid substitutions in the evolved OsALS1,derived from two sites that have never been targeted by natural or human selection during rice dom estication,were identified,conferring varying levels of tolerance to the herbicide bispyribac-sodium.Furtherm ore,the P171F substitution identified in a strong OsALS1 allele was quickly introduced into the commercial rice cultivar Nangeng 46 through precise base editing w ith the corresponding base editor and sgRNA.Collectively,these data indicate great potential of BEMGE in creating important genetic variants of target genes for crop improvement. | Yongjie Kuang Shaofang Li Bin Ren Fang Yan Carl Spetz Xiangju Li Xueping Zhou Huanbin Zhou | 2020 | Molecular Plant2020，13，4： | 37 |
| 2 | Path planning for taxi of carrier aircraft launching显示文摘Launching efficiency is an important index to measure the fighting capacity of an aircraft carrier. The study on path planning for taxi of carrier aircraft is of great significance for enhancing the launching efficiency. Considering the launching efficiency and the safety in operation of carrier aircraft launching and taking into account the carrier aircraft maneuver performance, deck environment and feature of mission, we proposed a conceptual model which contains the key elements of path planning for taxi of carrier aircraft. Subsequently, the objective function for the path planning problem and its mathematical model containing various constraints were established. With the A * search algorithm, a dynamic weight heuristic function was designed. According to the characteristic of path planning model for taxi of carrier aircraft, a simple and effective detection method was introduced. Finally, a feasible path for taxi of carrier aircraft, which meets the constraints, was presented. Taking the Nimitz-class aircraft carrier as an example, the paths for taxi of carrier aircraft launching from elevators to catapults were planned. Simulation results demonstrated the rationality of the model and the effectiveness of the algorithm. | WU Yu QU XiangJu | 2013 | Science China(Technological Sciences)2013，56，6： | 19 |
| 3 | Obstacle avoidance and path planning for carrier aircraft launching显示文摘Launching safety and efficiency are important indexes to measure the fighting capacity of carrier.The study on path planning for taxi of carrier aircraft launching under actual deck environment is of great significance.In actual deck scheduling,manual command is applied to taxi of carrier aircraft,which has negative effects on the safety of staff and carrier aircraft launching.In consideration of both the safety and efficiency of carrier aircraft launching,the key elements of the problem are abstracted based on the analysis of deck environment,carrier aircraft maneuver performance and task requirements.According to the problem description,the mathematical model is established including various constraints.The carrier aircraft and the obstacles are reasonably simplified as circle and polygons respectively.What’s more,the proposed collision detection model reduces the calculations.Aimed at the features of model,the theory of model predictive control(MPC)is applied to the path search.Then a dynamic weight heuristic function is designed and a dynamic multistep optimization algorithm is proposed.Taking the Nimitz-class aircraft carrier as an example,the paths from parking place to catapult are planned,which indicate the rationality of the model and the effectiveness of the algorithm by comparing the planning results under different simulation environments.The main contribution of research is the establishment of obstacle avoidance and path planning model.In addition,it provides the solution of model and technological foundations for comprehensive command and real-time decision-making of the carrier aircraft. | Wu Yu Qu Xiangju | 2015 | Chinese Journal of Aeronautics2015，28，3： | 18 |
| 4 | Study of Multi-objective Fuzzy Optimization for Path Planning显示文摘在路径计划期间,满足多重目的要求是必要的。多客观的合成基于飞行使命的需要和决策人的主观倾斜。然而,决策人为理解多重目的和主观倾斜的要求有不清不楚。为在多客观的路径计划描述决策人的不清不楚开发一个合理费用表演索引是重要的。为计划的路径基于 Voronoi 图方法,这份报纸学习多客观的费用表演索引的合成方法。根据到基于 Voronoi 图方法计划的路径的费用性能索引的应用程序,这份报纸分析目前被指了的费用性能索引。分析目前显示出费用表演索引的不足,即,综合是困难的因为次目标功能的大不同,次目标工作。因此,一条新途径被开发与多客观的模糊优化策略优化费用性能索引,并且一个改进性能索引被建立它能协调次目标函数的重量冲突。最后,试验性的结果显示出建议途径的有效性。 | WANG Yanyang WEI Tietao QU Xiangju | 2012 | Chinese Journal of Aeronautics2012，25，1： | 12 |
| 5 | Enhanced aromatic selectivity by the sheet-like ZSM-5 in syngas conversion显示文摘Aromatics are important basic chemicals. However, direct conversion of syngas via the conventional Fischer-Tropsch synthesis produces little aromatics. We presented herein that a bifunctional composite of ZSM-5 in combination with Zn Cr Oxcatalyzes syngas conversion to aromatics. Particularly, ZSM-5 crystals with a sheet-like morphology can enhance significantly the aromatization activity. The lower length ratio of the b/a axes of the crystals, the more aromatics form but without influencing the selectivity of small molecules such as CH4 and C2–C4. Since the acid properties and the Al chemical environment were not altered while the morphology changed, the enhanced aromatic selectivity is likely attributed to the favored diffusion of aromatics in these sheet-like crystals. | Junhao Yang Ke Gong Dengyun Miao Feng Jiao Xiulian Pan Xiangju Meng Fengshou Xiao Xinhe Bao | 2019 | Journal of Energy Chemistry2019，28，8： | 10 |
| 6 | Selective catalytic reduction of NO_(x) with NH_(3):opportunities and challenges of Cu-based small-pore zeolites显示文摘Zeolites,as efficient and stable catalysts,are widely used in the environmental catalysis field.Typically,Cu-SSZ-13 with small-pore structure shows excellent catalytic activity for selective catalytic reduction of NO_(x) with ammonia(NH_(3)-SCR)as well as high hydrothermal stability.This review summarizes major advances in Cu-SSZ-13 applied to the NH_(3)-SCR reaction,including the state of copper species,standard and fast SCR reaction mechanism,hydrothermal deactivation mechanism,poisoning resistance and synthetic methodology.The review gives a valuable summary of new insights into the matching between SCR catalyst design principles and the characteristics of Cu^(2+)-exchanged zeolitic catalysts,highlighting the significant opportunity presented by zeolite-based catalysts.Principles for designing zeolites with excellent NH_(3)-SCR performance and hydrothermal stability are proposed.On the basis of these principles,more hydrothermally stable Cu-AEI and Cu-LTA zeolites are elaborated as well as other alternative zeolites applied to NH_(3)-SCR.Finally,we call attention to the challenges facing Cu-based small-pore zeolites that still need to be addressed. | Yulong Shan Jinpeng Du Yan Zhang Wenpo Shan Xiaoyan Shi Yunbo Yu Runduo Zhang Xiangju Meng Feng-Shou Xiao Hong He | 2021 | National Science Review2021，8，10： | 9 |
| 7 | Mesoporous zeolites as efficient catalysts for oil refining and natural gas conversion显示文摘 | Jie ZHU Xiangju MENG Fengshou XIAO | 2013 | Frontiers of Chemical Science and Engineering2013，7，2： | 8 |
| 8 | Selective conversion of syngas to propane over ZnCrO_x-SSZ-39 OX-ZEO catalysts显示文摘Oxide-Zeolite(OX-ZEO) bifunctional catalyst design concept has been exemplified in several processes to direct conversion syngas to value-added chemicals and fuels such as mixed light olefins, ethylene, aromatics and gasoline.Herein we demonstrate that the product can be steered toward liquefied petroleum gas(LPG) with a selectivity up to 89% in hydrocarbons especially propane selectivity reaching 80% at CO conversion of 63% using ZnCrOx-H-SSZ-39 catalyst.Interestingly, the quantity of the acid sites of SSZ-39 does not influence obviously the hydrocarbon distribution but the strength is crucial for selective formation of propane.This finding provides an alternative route of LPG synthesis from a variety of carbon resources via syngas. | Gen Li Feng Jiao Dengyun Miao Yong Wang Xiulian Pan Toshiyuki Yokoi Xiangju Meng Feng-Shou Xiao Andrei-Nicolae Parvulescu Ulrich Müller Xinhe Bao | 2019 | Journal of Energy Chemistry2019，28，9： | 6 |
| 9 | A Novel CdS/g-C3N4 Composite Photocatalyst: Preparation, Characterization and Photocatalytic Performance with Different Reaction Solvents under Visible Light Irradiation显示文摘 | Xiangju Ye Xia Dai Sugang Meng Xianliang Fu Shifu Chen | 2017 | Chinese Journal of Chemistry2017，35，2： | 6 |
| 10 | Exploring mission planning method for a team of carrier aircraft launching显示文摘High-level efficiency and safety are of great significance for improving the fighting capability of an aircraft carrier. One way to enhance efficiency and safety level is to organize the carrier aircraft into combat effectively. This paper studies the mission planning problem for a team of carrier aircraft launching, and a novel distributed mission planning architecture is proposed. The architecture is hierarchical and is comprised of four levels, namely, the input level, the coordination level,the path planning level and the execution level. Realistic constraints in each level of the distributed architecture, such as the vortex flow effect, the crowd effect and the motion of aircraft, are considered in the model. To solve this problem, a distributed path planning algorithm based on the asynchronous planning strategy is developed. The proposed Mission Planning Approach for Carrier Aircraft Launching(MPACAL) is validated using the setups of the Nimitz-class aircraft carrier.Compared to the isolated planning architecture and the centralized planning architecture, the proposed distributed planning architecture has advantages in coordinating the launch tasks not only belonging to the same catapult but also when all different catapults are considered. The proposed MPACAL provides a modeling method for the flight deck operation on aircraft carrier. | Yu WU Yanyang WANG Xiangju QU Liguo SUN | 2019 | Chinese Journal of Aeronautics2019，32，5： | 6 |
| 11 | Solvent-free synthesis of zeolite catalysts显示文摘The most used method for preparation of zeolites is hydrothermal synthesis from silicate or aluminosilicate gels at temperatures in the range of 60–200°C.Excess water used in the industrial process results in several issues,including high autogeneous pressure,low efficiency,pollution,etc.To solve these problems,several strategies have been developed.This review describes the solvent-free synthesis of zeolites.The combination of solvent-free synthesis and organotemplate-free synthesis can open the pathway to a highly sustainable zeolite synthesis protocol in industry. | Xiangju Meng Qinming Wu Fang Chen Feng-Shou Xiao | 2015 | Science China Chemistry2015，58，1： | 5 |
| 12 | Correlation between podocyte excretion and proteinuria in diabetic nephropathy patients显示文摘Objective:To observe the podocyte injury in diabetic nephropathy(DN) patients by identifying the urinary podocytes and the situation of detached podocytes in glomeruli and to demonstrate the correlation between podocyte excretion and proteinuria,blood glucose,serum creatinine in different phases in DN patients.Methods:Urinary podocytes and the podocalyxin(PCX) expression state of podocytes in glomeruli were identified and observed by indirect immunofluorescent method.The DN patients were divided into three groups according to the volume of proteinuria,namely small,medium and large volume proteinuria groups.The podocytes in the urine of every group were calculated.The DN patients were divided into five groups according to the chronic kidney disease(CKD) phases,then the positive podocytes in urine were calculated.Meanwhile,the 24-hour protein in urine,fasting blood glucose(FBG) and the serum creatinine of DN patients were tested.The correlations among the proteinuria,serum creatinine,FBG and the number of positive podocytes in the urine of DN patients were statistically analyzed.Results:Urinary positive podocytes were found in 88% of the patients with DN,whereas podocytes were found in 0% of patients with minimal changed disease(MCD) and healthy cases.The expression of PCX was absent in DN patients.In contrast,PCX was expressed integrally in MCD patients.The positive podocytes was 1.49±0.95/ml in small-volume proteinuria group,2.15±0.70/ml in the medium-volume proteinuria group,and 3.48±1.27/ml in the large-volume proteinuria group.There was no significant difference between the small-and medium-volume proteinuria groups,and there were significant differences between other groups(P<0.05).The positive podocyte number tended to increase as proteinuria was increased.By Pearson analysis,the correlation between podocyte number and proteinuria was positive statistically.The difference of the number of positive podocytes in urine from different groups of DN patients,CKD Ⅰ-Ⅴ group was significant statistically.The correlation between serum creatinine of CKD Ⅰ-Ⅲ group and positive podocytes in urine was positive statistically.The correlation between serum creatinine of CKD Ⅳ-Ⅴ group and positive podocytes in urine was not significant statistically.The correlation between FBG and positive podocytes in urine was not significant either.Conclusion:The mechanism of the podocyte injury in DN patients is present.The podocyte injury in DN may positively correlate to proteinuria and serum creatinine of CKD Ⅰ-Ⅲ DN patients,but not to the FBG and serum creatinine of CKD Ⅳ-Ⅴ patients. | Long Xiangju Lin Shan Zhang Xin Shang Wenya | 2010 | Journal of Medical Colleges of PLA(China)2010，25，3： | 4 |
| 13 | Multi-body dynamic system simulation of carrier-based aircraft ski-jump takeoff显示文摘The flight safety is threatened by the special flight conditions and the low speed of carrier-based aircraft ski-jump takeoff. The aircraft carrier motion, aircraft dynamics, landing gears and wind field of sea state are comprehensively considered to dispose this multidiscipline intersection problem. According to the particular naval operating environment of the carrier-based aircraft ski-jump takeoff, the integrated dynamic simulation models of multi-body system are developed, which involves the movement entities of the carrier, the aircraft and the landing gears, and involves takeoff instruction, control system and the deck wind disturbance. Based on Matlab/Simulink environment, the multi-body system simulation is realized. The validity of the model and the rationality of the result are verified by an example simulation of carrier-based aircraft ski-jump takeoff. The simulation model and the software are suitable for the study of the multidiscipline intersection problems which are involved in the performance, flight quality and safety of carrier-based aircraft takeoff, the effects of landing gear loads, parameters of carrier deck, etc. | Wang Yangang Wang Weijun Qu Xiangju | 2013 | Chinese Journal of Aeronautics2013，26，1： | 4 |
| 14 | Effect of intermittent aeration mode on nitrogen concentration in the water column and sediment pore water of aquaculture ponds显示文摘Nitrogen in pond sediments is a major water quality concern and can impact the productivity of aquaculture.Dissolved oxygen is an important factor for improving water quality and boosting fish growth in aquaculture ponds,and plays an important role in the conversion of ammonium-nitrogen(NH4-N)to nitrite-nitrogen(NO2--N)and eventually nitrate-nitrogen(NO3--N).A central goal of the study was to identify the best aeration method and strategy for improving water quality in aquaculture ponds.We conducted an experiment with six tanks,each with a different aeration mode to simulate the behavior of aquaculture ponds.The results show that a 36 hr aeration interval(Tc=36 hr:36 hr)and no aeration resulted in high concentrations of NH4-N in the water column.Using a 12 hr interval time(Tc=12 hr:12 hr)resulted in higher NO2--N and NO3--N concentrations than any other aeration mode.Results from an 8 hr interval time(Tc=8 hr:8 hr)and 24 hr interval time(Tc=24 hr:24 hr)were comparable with those of continuous aeration,and had the benefit of being in use for only half of the time,consequently reducing energy consumption. | Dantong Zhu Xiangju Cheng David J.Sample Mohammad Nayeb Yazdi | 2020 | Journal of Environmental Sciences2020，32，4： | 4 |
| 15 | Time-varying linear control for tiltrotor aircraft显示文摘Tiltrotor aircraft have three flight modes: helicopter mode, airplane mode, and transition mode. A tiltrotor has characteristics of highly nonlinear, time-varying flight dynamics and inertial/-control couplings in its transition mode. It can transit from the helicopter mode to the airplane mode by tilting its nacelles, and an effective controller is crucial to accomplish tilting transition missions. Longitudinal dynamic characteristics of the tiltrotor are described by a nonlinear Lagrangeform model, which takes into account inertial/control couplings and aerodynamic interferences.Reference commands for airspeed velocity and attitude in the transition mode are calculated dynamically by visiting a command library which is founded in advance by analyzing the flight envelope of the tiltrotor. A Time-Varying Linear(TVL) model is obtained using a Taylorexpansion based online linearization technique from the nonlinear model. Subsequently, based on an optimal control concept, an online optimization based control method with input constraints considered is proposed. To validate the proposed control method, three typical tilting transition missions are simulated using the nonlinear model of XV-15 tiltrotor aircraft. Simulation results show that the controller can be used to control the tiltrotor throughout its operating envelop which includes a transition flight, and can also deal with vertical gust disturbances. | Jing ZHANG Liguo SUN Xiangju QU Liuping WANG | 2018 | Chinese Journal of Aeronautics2018，31，4： | 4 |
| 16 | Efficient conversion of fructose to 5-hydroxymethylfurfural over sulfated porous carbon catalyst显示文摘Sulfated porous carbon (PC-SO3H) catalyst was successfully synthesized from one-pot treatment of porous polydivinylbenzene in H2SO4 at 250 C, which exhibited very good catalytic performances in the production of 5-hydroxymethylfurfural from fructose. | Liang Wang Jian Zhang Longfeng Zhu Xiangju Meng Feng-Shou Xiao | 2013 | Journal of Energy Chemistry2013，22，2： | 4 |
| 17 | Prediction of nonlinear pilot-induced oscillation using an intelligent human pilot model显示文摘This paper proposes a method to predict nonlinear Pilot-Induced Oscillation(PIO)using an intelligent human pilot model.This method is based on a scalogram-based PIO metric,which uses wavelet transforms to analyze the nonlinear characteristics of a time-varying system.The intelligent human pilot model includes three modules:perception module,decision and adaptive module,and execution module.Intelligent and adaptive features,including a neural network receptor,fuzzy decision and adaptation,are also introduced into the human pilot model to describe the behavior of the human pilot accommodating the nonlinear events.Furthermore,an algorithm is proposed to describe the procedure of the PIO prediction method with nonlinear evaluation cases.The prediction results obtained by numerical simulation are compared with the assessments of flight test data to validate the utility of the method.The flight test data were generated in the evaluation of the Smart-Cue/Smart-Gain,which is capable of reducing the PIO tendencies considerably.The results show that the method can be applied to predict the nonlinear PIO events by human pilot model simulation. | Shuting XU Wenqian TAN Xiangju QU Cheng ZHANG | 2019 | Chinese Journal of Aeronautics2019，32，12： | 3 |
| 18 | Sustainable Synthesis of Core-Shell Structured ZSM-5@Silicalite-1 Zeolite显示文摘Core-shell structured ZSM-5@Silicalite-1 zeolite could effectively hinder the deactivation of catalyst surface. Currently, organic structure directing agents(OSDAs) are necessary in the conventional route for the synthesis of this core-shell zeolite under hydrothermal conditions, which is costly and environmental-unfriendly. In this research, a synthesis of the core-shell structured ZSM-5@Silicalite-1 zeolite with a strategy of alcohol filling and zeolite seeding without any organic template or solvent is exhibited. The obtained products are well characterized by X-ray powder diffractometer(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM), N2 sorption isotherms, solid magic angle spinning(MAS) NMR, temperature-programmed-desorption of ammonia(NH3-TPD), and X-ray photoelectron spectroscopy(XPS) techniques, in order to confirm the core-shell structure. More importantly, the core-shell structured ZSM-5@Silicalite-1 zeolite exhibits a long lifetime and a high p-xylene selectivity in the alkylation of toluene with methanol, compared with the conventional ZSM-5 catalyst. | LUAN Huimin WU Qinming ZHANG Jian WANG Yeqing MENG Xiangju XIAO Feng-Shou | 2022 | Chemical Research in Chinese Universities2022，38，1： | 3 |
| 19 | A new phosphidation route for the synthesis of NiPx and their cocatalytic performances for photocatalytic hydrogen evolution over g-C3N4显示文摘Ni-based phosphides(NiPx)composed of earth-abundant elements are promising cocatalysts to replace noble metals for photocatalytic H2 evolution reaction(HER).A safe,energy-saving,and compositioncontrollable synthesis of NiPx is still highly desired.A facile and mild solvothermal process was developed for the first time for selective synthesis of a series of NiPx,including Ni,Ni12P5,Ni2P/Ni12P5,Ni/Ni2P and Ni2P,through controlling the dosage of NaBH4 and NaH2PO2.The phosphidation process was mainly composed of(1)a sequential reduction of Ni2+to Nj0 and(H2PO2)-to P(around the formed Ni0)triggered by NaBH4,and(2)a final phosphidation between Nj0 and the in situ generated P atoms.The photocatalytic HER performance of g-C3N4 can be substantially improved with the decoration of NiPx(3 wt%)as the separation of photoinduced charge carriers can be promoted and some active sites with low over-potential for HER can be introduced.The cocatalytic efficiency of NiPx is mainly determined by P content.Ni2P with a high ratio of P consequently exhibits the highest HER performance(215.1 umol g-1 h-1),which is almost six times higher than that of the pristine g-C3N4(35.6 umol g-1 h-1).Thus,as for the cocatalyst based on Ni phosphides,Ni2P is the preferable crystal phase and more efforts should be devoted to Ni2P to further optimize its structure,texture,and morphology in future works. | Ziqun Wang Longfeng Li Mingzhu Liu Tifang Miao Xiangju Ye Sugang Meng Shifu Chen Xianliang Fu | 2020 | Journal of Energy Chemistry2020，29，9： | 2 |
| 20 | Acetolactate synthase proline (197) mutations confer tribenuron-methyl resistance in Capsella bursa-pastoris populations from China显示文摘 | Hai lan Cui Xiangju Li Guiqi Wang Jianping Wang Shouhui Wei Hongyu Cao | 2012 | Pesticide Biochemistry and Physiology2012，，3： | 2 |
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