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| 1 | Composition, origin and weathering process of surface sediment in Kumtagh Desert, Northwest China显示文摘Kumtagh 沙漠是在中国的八最大的沙漠之一,但是因为存取的困难,以前糟糕调查我们的学科交差的学习。在这份报纸, 33 件代表性的表面沉积样品从在实验室荒芜、分析的 Kumtagh 被收集获得重矿物质部件和 geochemical 元素内容。结果证明重矿物质的各种各样的类型在这些样品是在场的,与绿帘石和角闪石的高水平。Si 和艾尔收起化学作文的大部分。与上面的大陆人外壳(UCC ) 的 geochemical 元素的平均作文相比,除了 Si 和 Ca,所有元素被弄空到某个度;Fe, Mg, Ca, P, Ti 和 Mn 在他们的内容有高关联系数。矿物质和 Kumtagh 荒芜的沉积的 geochemical 作文在 Altyn Tagh 山脉和 Taklamakan 沙漠的附近与 Altyn Tagh 山脉,和冲积/洪水的扇子的表面沉积的岩石的有类似,显示 Kumtagh 荒芜的沉积的一主要来源位于 Altyn Tagh 山脉。在 Aqik 山谷和 Shule 河的更低的活动范围的冲积沉积物和湖沉积是容易的被侵蚀并且搬运由强壮在东北弯屈进 Kumtagh 沙漠,形成沙漠的另一来源扔。一张 A-CN-K 第三的图证明由 Na 和 K 的损失捱过的弱度化学药品发生在这些沉积,而 A-CNK-FM 第三的图建议 Fe 和 Mg 经历了重要化学区别。物理捱过过程为 mafic 矿物质在好粒子引起容易的侵蚀和丰富,这样粗糙的荒芜的沙粒子能相对在 Fe 和 Mg 被弄空。在经历不太化学的捱过的干旱区域的沉积的矿物质和 geochemical 作文被物理捱过主要影响。 | XU Zhiwei LU Huayu ZHAO Cunfa WANG Xianyan SU Zhizhu WANG Zhenting LIU Hongyi WANG Lixin LU Qi | 2011 | Journal of Geographical Sciences2011，21，6： | 13 |
| 2 | Earth surface processes and their effects on human behavior in monsoonal China during the Pleistocene-Holocene epochs显示文摘There is a wide diversity of landforms in China.The topography of three major terraces,decreasing in height stepwise from west to east,was formed by the early Miocene.With the commencement of the Great Northern Hemisphere Glaciations(GHGs)and the glacial-interglacial cycles in the Pleistocene,thick loess deposits accumulated in north China,and fluvial terraces were formed and lakes expanded and contracted in eastern and central China.The earliest evidence of hominins in China is dated to ~1.7 Ma;they occupied the monsoon-dominated region for a long interval,until the late Pleistocene,~50 ka.In this study,we investigated a large area rich in the relics and artifacts of early man.The results indicate that the early humans occupied riverine areas,especially medium-sized fluvial basins,and lake shores.Even in the relatively recent geological past,the occupation and abandonment of settlements were directly forced by the shifting of sand dune fields in the desert-loess transitional zone,which in turn was closely associated with variations in the monsoon climate and vegetation patterns.Our observations indicate that landforms were one of the main determinants of early human behavior,in that loess tableland,large alluvial plains,desert-Gobi areas,and the Tibetan Plateau,were not suitable environments for early human settlement.We infer that the early humans in China adapted their behavior to specific landforms and landform processes.The monsoon climate,which shapes the large-scale step-like pattern of fluvial landforms,promotes vegetation coverage and dominates soil formation,provides a crucial context for early human adaptation.The adaptation of early humans to earth surface processes in East Asia is investigated for the first time in this study.Future investigations will provide further information that will increase our understanding of the linkage between early human behavior and landform processes in East Asia. | LU Huayu ZHUO Haixin ZHANG Wenchao WANG Shejiang ZHANG Hongyan SUN Xuefeng JIA Xin XU Zhiwei WANG Xianyan | 2017 | Journal of Geographical Sciences2017，27，11： | 12 |
| 3 | Bone tissue regeneration:The role of finely tuned pore architecture of bioactive scaffolds before clinical translation显示文摘Spatial dimension of pores and interconnection in macroporous scaffolds is of particular importance in facilitating endogenous cell migration and bone tissue ingrowth.However,it is still a challenge to widely tune structure parameters of scaffolds by conventional methods because of inevitable pore geometrical deformation and poor pore interconnectivity.Here,the long-term in vivo biological performances of nonstoichiometric bioceramic scaffolds with different pore dimensions were assessed in critical-size femoral bone defect model.The 6%Mg-substituted wollastonite(CSi-Mg6)powders were prepared via wet-chemical precipitation and the scaffolds elaborately printed by ceramic stereolithography,displaying designed constant pore strut and tailorable pore height(200,320,450,600μm),were investigated thoroughly in the bone regeneration process.Together with detailed structural stability and mechanical properties were collaboratively outlined.BothμCT and histological analyses indicated that bone tissue ingrowth was retarded in 200μm scaffolds in the whole stage(2-16 weeks)but the 320μm scaffolds showed appreciable bone tissue in the center of porous constructs at 6-10 weeks and matured bone tissue were uniformly invaded in the whole pore networks at 16 weeks.Interestingly,the neo-tissue ingrowth was facilitated in the 450μm and 600μm scaffolds after 2 weeks and higher extent of bone regeneration and remodeling at the later stage.These new findings provide critical information on how engineered porous architecture impact bone regeneration in vivo.Simultaneously,this study shows important implications for optimizing the porous scaffolds design by advanced additive manufacture technique to match the clinical translation with high performance. | Ronghuan Wu Yifan Li Miaoda Shen Xianyan Yang Lei Zhang Xiurong Ke Guojing Yang Changyou Gao Zhongru Gou Sanzhong Xu | 2021 | Bioactive Materials2021，6，5： | 5 |
| 4 | 3D printing of Mg-substituted wollastonite reinforcing diopside porous bioceramics with enhanced mechanical and biological performances显示文摘Mechanical strength and its long-term stability of bioceramic scaffolds is still a problem to treat the osteonecrosis of the femoral head.Considering the long-term stability of diopside(DIO)ceramic but poor mechanical strength,we developed the DIO-based porous bioceramic composites via dilute magnesium substituted wollastonite reinforcing and three-dimensional(3D)printing.The experimental results showed that the secondary phase(i.e.10%magnesium substituting calcium silicate;CSM10)could readily improve the sintering property of the bioceramic composites(DIO/CSM10-x,x=0-30)with increasing the CSM10 content from 0%to 30%,and the presence of the CSM10 also improved the biomimetic apatite mineralization ability in the pore struts of the scaffolds.Furthermore,the flexible strength(12.5 -30 MPa)and compressive strength(14-37 MPa)of the 3D printed porous bioceramics remarkably increased with increasing CSM10 content,and the compressive strength of DIO/CSM10-30 showed a limited decay(from 37 MPa to 29 MPa)in the Tris buffer solution for a long time stage(8 weeks).These findings suggest that the new CSM10-reinforced diopside porous constructs possess excellent mechanical properties and can potentially be used to the clinic,especially for the treatment of osteonecrosis of the femoral head work as a bioceramic rod. | Dongshuang He Chen Zhuang Sanzhong Xu Xiurong Ke Xianyan Yang Lei Zhang Guojing Yang Xiaoyi Chen Xiaozhou Mou An Liu Zhongru Gou | 2016 | Bioactive Materials2016，1，1： | 5 |
| 5 | An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis显示文摘Localized delivery,comparing to systemic drug administration,offers a unique alternative to enhance efficacy,lower dosage,and minimize systemic tissue toxicity by releasing therapeutics locally and specifically to the site of interests.Herein,a localized drug delivery platform ('plum?pudding'structure) with controlled release and long-acting features is developed through an injectable hydrogel ('pudding') crosslinked via self-assembled triblock polymeric micelles ('plum') to help reduce renal interstitial fibrosis.This strategy achieves controlled and prolonged release of model therapeutics in the kidney for up to three weeks in mice.Following a single injection,local treatments containing either anti-inflammatory small molecule celastrol or anti-TGFb antibody effectively minimize inflammation while alleviating fibrosis via inhibiting NF-k B signaling pathway or neutralizing TGF-b1 locally.Importantly,the micelle-hydrogel hybrid based localized therapy shows enhanced efficacy without local or systemic toxicity,which may represent a clinically relevant delivery platform in the management of renal interstitial fibrosis. | Xianyan Qin Yingying Xu Xu Zhou Tao Gong Zhi-Rong Zhang Yao Fu | 2021 | Acta Pharmaceutica Sinica B2021，11，3： | 2 |
| 6 | Synthesis and characterization of expandable graphite-poly(methyl meth- acrylate) composite particles and their application to flame retardation of rigid polyurethane foams显示文摘 | Ye Ling Meng Xianyan Ji Xu | 2009 | Poly- mer Degradation and Stability2009，94，6： | 1 |
| 7 | Synthesis and char- acterization of expandable graphite-poly (methyl methae- rylate) composite particles and their application to flame retardation of rigid polyurethane foams显示文摘 | Ye Ling Meng Xianyan Ji Xu | 2009 | Polymer Deg- radation and Stability2009，94，6： | 1 |
| 8 | Synthesis and charac- terization of expandable graphite-poly(methyl methacrylate) composite particles and their application to flame retardation of rigid polyurethane foams显示文摘 | Ye Ling Meng Xianyan Xu Ji | 2009 | Polym Degrad Stab2009，，94： | 1 |
| 9 | Study on the distribution of non-point source pollution in the watershed of Miyun reservoir,Beijing,China显示文摘 | Wang Xianyan Li Tin Xu Qian | 2001 | Water Science and Technology2001，44，7： | 1 |
| 10 | Synthesis andcharacterization of expandable graphite-poly ( methyl-methacrylate) composite particles and their applicationto flameretardation of rigid polyurethane foams 显示文摘 | Ye Ling Meng Xianyan Ji Xu | 2009 | Polymer Degradation and Stability2009，94，： | 1 |
| 11 | Synthesis and characterization of expandable graphite-poly(methyl methacrylate) composite particles and their application to flame retardation of rigid polyurethane foams 显示文摘 | Ling Ye Xianyan Meng Xu Ji | 2009 | Polymer Degradation and Stability2009，94，： | 1 |
| 12 | Bioceramic scaffolds with triply periodic minimal surface architectures guide early-stage bone regeneration显示文摘The pore architecture of porous scaffolds is a critical factor in osteogenesis,but it is a challenge to precisely configure strut-based scaffolds because of the inevitable filament corner and pore geometry deformation.This study provides a pore architecture tailoring strategy in which a series of Mg-doped wollastonite scaffolds with fully interconnected pore networks and curved pore architectures called triply periodic minimal surfaces(TPMS),which are similar to cancellous bone,are fabricated by a digital light processing technique.The sheet-TPMS pore geometries(s-Diamond,s-Gyroid)contribute to a 3‒4-fold higher initial compressive strength and 20%-40%faster Mg-ion-release rate compared to the other-TPMS scaffolds,including Diamond,Gyroid,and the Schoen’s I-graph-Wrapped Package(IWP)in vitro.However,we found that Gyroid and Diamond pore scaffolds can significantly induce osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs).Analyses of rabbit experiments in vivo show that the regeneration of bone tissue in the sheet-TPMS pore geometry is delayed;on the other hand,Diamond and Gyroid pore scaffolds show notable neo-bone tissue in the center pore regions during the early stages(3-5 weeks)and the bone tissue uniformly fills the whole porous network after 7 weeks.Collectively,the design methods in this study provide an important perspective for optimizing the pore architecture design of bioceramic scaffolds to accelerate the rate of osteogenesis and promote the clinical translation of bioceramic scaffolds in the repair of bone defects. | Miaoda Shen Yifan Li Fengling Lu Yahui Gou Cheng Zhong Shukun He Chenchen Zhao Guojing Yang Lei Zhang Xianyan Yang Zhongru Gou Sanzhong Xu | 2023 | Bioactive Materials2023，，7： | 1 |
| 13 | Biomaterial coatings by stepwise deposition of silk fibroin 显示文摘 | Wang Xianyan Kim HJ Xu Peng | 2005 | American Chemical Society2005，21，11： | 1 |
| 14 | An overview of cetacean strandings, bycatches and rescues along the western coast of the Taiwan Strait, China: 2010–2015显示文摘The analysis of cetacean strandings can provide fundamental information about species diversity and composition in a particular region. The present study collected and analyzed cetacean strandings, bycatches and rescues along the western coast of the Taiwan Strait, China, from 2010 to 2015. In total, 48 records, including 37 strandings, 8 bycatches and 3 rescues, involving 13 known species were collected. Among them, Indo-Pacific humpback dolphins(Sousa chinensis) and finless porpoises(Neophocaena phocaenoides) were the most common species, consisting of 31.3% and 25%, respectively. Notably, 10 out of the 48(20.8%) records were collected from the Pingtan Island and included 3 species of Mysticeti and 4 species of Odontoceti. Finally, we compared the cetacean species composition between the western and eastern coasts of the Taiwan Strait; 31 cetacean species occurred in the Taiwan Strait, indicating a relatively high cetacean diversity in this region. Systematic field surveys are urgently needed to explore the cetacean species composition, population stock and the related habitat status in the Taiwan Strait, which may improve conservation management in the future. | ZHAO Liyuan ZHU Qian MIAO Xing XU Min WU Fuxing DAI Yufei TAO Cuihua MOU Jianfeng WANG Xianyan | 2017 | Acta Oceanologica Sinica2017，36，12： | 1 |
| 15 | Binding energies and interaction origins between nonclassical single-electron hydrogen,sodium and lithium bonds and neutral boron-containing radicals:a theoretical investigation显示文摘Nonclassical single electron hydrogen,sodium and lithium bonds(SEHBs,SENaBs and SELiBs)between single electron acceptors X–A(A=H,Na,Li;X=CN,HCC,HO,NC,CF3)and neutral radicals BY2(Y=H,OH,CH3)and have been systematically investigated by high level theoretical methods,such as second-order Mφller-Plesset perturbation theory(MP2),spin-component-scaled MφllerPlesset theory(SCS-MP2),the coupled cluster method with perturbative triples(CCSD(T)),and the correlation consistent composite approach(ccCA).Binding energies have been corrected for zero-point vibrational effects and(when applicable)basis set superposition error.The quantum theory of atoms in molecules(AIM)and natural bond orbital(NBO)analyses were also employed to qualitatively characterize the single electron bond interactions.The stabilization energy was partitioned via the localized molecular orbital energy decomposition analysis(LMOEDA)method,and both electrostatic and exchange interactions were seen to be major driving forces for the complex stabilization.Interestingly,the sum of the energy contributors of exchange(EEX),repulsion(EREP),polarization(EPOL),dispersion(EDIS)is close to zero and the changes in the interaction energy follow the trend of the electrostatic energy(EES).We observe several linear relationships among the optimized intermolecular parameters and the interaction energies of the various complexes. | Zhifeng Li Xiaoping Yang Nathan J.DeYonker Xianyan Xu Zhen Guo Cunyuan Zhao | 2014 | Chinese Science Bulletin2014，59，21： | 0 |
| 16 | Integrating pore architectures to evaluate vascularization efficacy in silicate-based bioceramic scaffolds显示文摘Pore architecture in bioceramic scaffolds plays an important role in facilitating vascularization efficiency during bone repair or orbital reconstruction.Many investigations have explored this relationship but lack integrating pore architectural features in a scaffold,hindering optimization of architectural parameters(geometry,size and curvature)to improve vascularization and consequently clinical outcomes.To address this challenge,we have developed an integrating design strategy to fabricate different pore architectures(cube,gyroid and hexagon)with different pore dimensions(-350,500 and 650 lm)in the silicate-based bioceramic scaffolds via digital light processing technique.The sintered scaffolds maintained high-fidelity pore architectures similar to the printing model.The hexagon-and gyroid-pore scaffolds exhibited the highest and lowest compressive strength(from 15 to 55MPa),respectively,but the cube-pore scaffolds showed appreciable elastic modulus.Moreover,the gyroid-pore architecture contributed on a faster ion dissolution and mass decay in vitro.It is interesting that bothμCT and histological analyses indicate vascularization efficiency was challenged even in the 650-μm pore region of hexagon-pore scaffolds within 2weeks in rabbit models,but the gyroid-pore constructs indicated appreciable blood vessel networks even in the 350-μm pore region at 2weeks and high-density blood vessels were uniformly invaded in the 500-and 650-μm pore at 4weeks.Angiogenesis was facilitated in the cube-pore scaffolds in comparison with the hexagon-pore ones within 4weeks.These studies demonstrate that the continuous pore wall curvature feature in gyroid-pore architecture is an important implication for biodegradation,vascular cell migration and vessel ingrowth in porous bioceramic scaffolds. | Fanghui Wu Jun Yang Xiurong Ke Shuo Ye Zhaonan Bao Xianyan Yang Cheng Zhong Miaoda Shen Sanzhong Xu Lei Zhang Zhongru Gou Guojing Yang | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
| 17 | Analysis of echolocation clicks from Indo-Pacific humpback dolphins(Sousa chinensis)and East Asian finless porpoises(Neophocaena asiaeorientalis sunmeri)显示文摘Echolocation clicks of Indo-Pacific humpback dolphins(Sousa chinensis)and East Asian finless porpoises(Neophocaena asiaeorientalis sunmeri)were recorded and analyzed to deepen our understandings on vocalizations variability of these two endangered species.Passive acoustic monitoring was used to record the clicks during boat-based field surveys in the Xiamen waters.Subsequent analyses show clicks emitted by Indo-Pacific humpback dolphins are characterized by short duration,high frequency,and broadband bandwidth.Comparatively,clicks of East Asian finless porpoise have a relatively longer duration,higher peak frequency,and narrower bandwidth.The duration,centroid frequency and-10 dB bandwidth of clicks are significantly different between these two species. | WANG Yueyun WANG Xianyan XU Xiaohui SONG Zhongchang YANG Wuyi ZHANG Yu | 2022 | Chinese Journal of Acoustics2022，41，2： | 0 |
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