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| 1 | Surface current field and seasonal variability in the Kuroshio and adjacent regions derived from satellite-tracked drifter data显示文摘The multiyear averaged surface current field and seasonal variability in the Kuroshio and adjacent regions are studied.The data used are trajectories and(1/4)° latitude by(1/4)° longitude mean currents derived from 323 Argos drifters deployed by Chinese institutions and world ocean circulation experiment from 1979 to 2003.The results show that the Kuroshio surface path adapts well to the western boundary topography and exhibits six great turnings.The branching occurs frequently near anticyclonic turnings rather than near cyclonic ones.In the Luzon Strait,the surface water intrusion into the South China Sea occurs only in fall and winter.The Kuroshio surface path east of Taiwan,China appears nearly as straight lines in summer,fall,and winter,when anticyclonic eddies coexist on its right side;while the path may cyclonically turning in spring when no eddy exists.The Kuroshio intrusion northeast of Taiwan often occurs in fall and winter,but not in summer.The running direction,width and velocity of the middle segment of the Kuroshio surface currents in the East China Sea vary seasonally.The northward intrusion of the Kuroshio surface water southwest of Kyushu occurs in spring and fall,but not in summer.The northmost position of the Kuroshio surface path southwest of Kyushu occurs in fall,but never goes beyond 31°N.The northward surface current east of the Ryukyu Islands exists only along Okinawa-Amami Islands from spring to fall.In particular,it appears as an arm of an anticyclonic eddy in fall. | HU Xiaomin XIONG Xuejun QIAO Fangli GUO Binghuo LIN Xiaopei | 2008 | Acta Oceanologica Sinica2008，27，3： | 23 |
| 2 | Improving Plant Genome Editing with High-Fidelity xCas9 and Non-canonical PAM-Targeting Cas9-NG显示文摘Two recently engineered SpCas9 variants, namely xCas9 and Cas9-NG, show promising potential in improving targeting specificity and broadening the targeting range. In this study, we evaluated these Cas9 variants in the model and crop plant, rice. We first tested xCas9-3.7, the most effective xCas9 variant in mammalian cells, for targeted mutagenesis at 16 possible NGN PAM (protospacer adjacent motif) combinations in duplicates. xCas9 exhibited nearly equivalent editing efficiency to wild-type Cas9 (Cas9-WT) at most canonical NGG PAM sites tested, whereas it showed limited activity at non-canonical NGH (H = A, C, T) PAM sites. High editing efficiency of xCas9 at NGG PAMs was further demonstrated with C to T base editing by both rAPOBECI and PmCDAI cytidine deaminases. With mismatched sgRNAs, we found that xCas9 had improved targeting specificity over the Cas9-WT. Furthermore, we tested two Cas9-NG variants, Cas9-NGv1 and Cas9-NG, for targeting NGN PAMs. Both Cas9-NG variants showed higher editing efficiency at most non-canonical NG PAM sites tested, and enabled much more efficient editing than xCas9 at AT-rich PAM sites such as GAT, GAA, and CAA. Nevertheless, we found that Cas9-NG variants showed significant reduced activity at the canonical NGG PAM sites. In stable transgenic rice lines, we demonstrated that Cas9-NG had much higher editing efficiency than Cas9-NGv1 and xCas9 at NG PAM sites. To expand the base-editing scope, we developed an efficient C to T base-editing system by making fusion of Cas9-NG nickase (D10A version), PmCDAI, and UGI. Taken together, our work benchmarked xCas9 as a high-fidelity nuclease for targeting canonical NGG PAMs and Cas9-NG as a preferred variant for targeting relaxed PAMs for plant genome editing. | Zhaohui Zhong Simon Sretenovic Qiurong Ren Lijia Yang Yu Bao Caiyan Qi Mingzhu Yuan Yao He Shishi Liu Xiaopei Liu Jiaheng Wang Lan Huang Yan Wang Dibin Baby David Wang Tao Zhang Yiping Qi Yong Zhang | 2019 | Molecular Plant2019，12，7： | 13 |
| 3 | Relationship Between Producer Services Developing Level and Urban Hierarchy——A Case Study of Zhujiang River Delta显示文摘As the Central Place Theory indicates, the centricity of a central city can influence the extension of its ser- vice. Since the service industry in the theory is mostly consumer services, it is worth studying the relationship between the producer services and the centricity of the city in the service society with producer services becoming a more im- portant part of the service industry. The paper takes the case of the Zhujiang (Pearl) River Delta (PRD), a developed region in China, to study the relationship between the developing level of producer services and the urban hierarchy. Based on the analysis about the spatial difference of the producer services in the nine cities of the PRD, and the divi- sion of the nine cities according to some economic indices, it is shown that there is a correlation between the develop- ing level of producer services and the urban hierarchy. Furthermore, two deductions about the future status of the pro- ducer services in the city and the location of the producer services in a large region can be made from this correlation between the developing level of producer services and the urban hierarchy. | ZHONG Yun YAN Xiaopei | 2008 | Chinese Geographical Science2008，18，1： | 11 |
| 4 | Analysis on the influencing factors of mechanical characteristics of jointless turnout group in ballasted track of high-speed railway显示文摘Turnouts are in close proximity to each other in the stations of high-speed railway.The stress and deformation of those turnouts which are laid nearby are influenced mutually and therefore those turnouts should be considered together.On the basis of finite element method,according to No.18 jointless turnout with swing nose frog in the ballasted track of high-speed railway,a finite element calculating model of jointless turnout group coupling the longitudinal,lateral and vertical directions is established.The influencing factors,for instance the number of turnouts,connection form,length of intermediate straight line and ballast bed longitudinal resistance,on the mechanical characteristics of turnout,transverse deformation of switch rail and range of rail temperature for laying turnout are analyzed in this paper.The results show that more turnouts result in more obvious interaction between them when the lengths of intermediate straight line are the same;more significant influence between the turnouts with the connection form of head-to-head is produced compared to that of head-to-end;from the perspective of statics,influence between turnouts could be ignored basically if the intermediate straight line is over 50 m;bigger longitudinal resistance of ballast bed leads to less influence between the turnouts. | GAO Liang QU Cun QIAO ShenLu CAI XiaoPei LIU Wei | 2013 | Science China(Technological Sciences)2013，56，2： | 10 |
| 5 | Plant Genome Editing Using FnCpfl and LbCpf Nucleases at Redefined and Altered PAM-Sites显示文摘 | ZhaohuiZhong Yingxiao Zhang Qi You XU Tang Qiurong Ren Shishi Liu Lijia Yang Yan Wang Xiaopei Liu Binglin Liu Tao Zhang Xuelian Zheng Ysa Le Yong Zhang Yiping Qi | 2018 | Molecular Plant2018，11，7： | 10 |
| 6 | Elastic-plastic seismic response of CRTS II slab ballastless track system on high-speed railway bridges显示文摘China railways track structure II (CRTS II) slab ballastless track on bridge is one kind of track structures unique to China. Its main bearing component of longitudinal force is the continuous base plate rather than rail. And the track-bridge interaction is weakened by the sliding layer installed between base plate and bridge deck. In order to study the dynamic response of CRTS II slab ballastless track on bridge under seismic action, a 3D nonlinear dynamic model for simply-supported bridges and CRTS II track was established, which considered structures such as steel rail, fasteners, track plate, mortar layer, base plate, sliding layer, bridge, consolidation, anchors, stoppers, etc. Then its force and deformation features under different intensities of seismic excitation were studied. As revealed, the seismic response of the system increases with the increase of seismic intensity. The peak stresses of rail, track plate and base plate all occur at the abutment or anchors. Both track plate and base plate are about to crack. Besides, the rapid relative displacement between base plate and bridge deck due to the small friction coefficient of sliding layer is beneficial to improve the seismic performance of the system. During the earthquake, a large vertical displacement appears in base plate which leads to frequent collisions between stoppers and base plate, as a result, stoppers may be damaged. | YAN Bin LIU Shi PU Hao DAI GongLian CAI XiaoPei | 2017 | Science China(Technological Sciences)2017，60，6： | 9 |
| 7 | Comparison of screening strategies for Lynch syndrome in patients with newly diagnosed endometrial cancer:a prospective cohort study in China显示文摘Background: The prevalence of Lynch syndrome and screening strategies for this disorder in Chinese patients with endometrial cancer have seldom been investigated. Such data would be essential for the screening, prevention, genetic counseling, and treatment of Lynch syndrome. The purpose of this prospective study was to determine the accuracy of the mismatch repair (MMR) protein immunohistochemistry (IHC), microsatellite instability (MSI) test, and clinical diagnostic criteria in screening for Lynch syndrome-associated endometrial cancer (LS-EC) in a prospective Chinese cohort. Methods: All patients with newly diagnosed endometrial cancer (EC) were evaluated using clinical diagnostic criteria (Amsterdam II criteria and the revised Bethesda guidelines), MSI test, and IHC of MMR proteins in tumor tissues. For all patients, the screening results were compared with results of germline sequencing for pathogenic variants of MMR genes. Results: Between December 2017 and August 2018, a total of 111 unselected patients with newly diagnosed EC were enrolled. Six patients (5.4%) harbored a pathogenic germline mutation of MMR genes: 1 had a mutation in MutL homolog 1 (MLH1), 2 in MutS homolog 2 (MSH2), and 3 in MutS homolog 6 (MSH6). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for identifying LS-EC were 33.3%, 88.6%, 14.3%, and 95.9%, for the clinical criteria, 66.7%, 75.0%, 14.3%, and 97.3% for IHC of MMR proteins, 100%, 89.9%, 33.3%, and 100% for MSI test, and 100%, 72.4%, 20.0% and 100% for combined IHC and MSI test, respectively. The combination of IHC and MSI test had higher sensitivity and PPV than the clinical criteria (p = 0.030). MSI test and IHC were highly concordant for LS-EC screening (73/77, 94.8%). Conclusion: The accuracy of the combination of IHC of MMR proteins and MSI test for screening LS among Chinese patients with EC was superior to that of the clinical criteria. | Xiaopei Chao Lei Li Ming Wu Shuiqing Ma Xianjie Tan Sen Zhong Yalan Bi Jinghe Lang | 2019 | Cancer Communications2019，39，1： | 8 |
| 8 | The seismic CT method in measuring rock bodies显示文摘地震计算断层摄影术(CT ) 方法从节扫描首先在医药科学使用了的 X 光检查的基本原则被导出。方法在分开的地上凿穿记录在射击和接收装置之间的 P 波浪到达。用从 2D 的速度信息地震 P 波浪到达倒置,我们能在岩石和土壤身体中决定速度的分发。这篇论文介绍使用地震 CT 方法为隧道工程并且到检测岩石的结构的一个实际盒子为做第一到达时间反复的倒置利用 SIRT 算法。与另外的探索方法相比,它更有效、精确。 | Du Lizhi Zhang Xiaopei Niu Jianjun Wang Xuege Feng Guolei | 2006 | Applied Geophysics2006，3，3： | 8 |
| 9 | 为细菌的房间的一个非凡的紧、敏感的光可切换的基因表达式系统显示文摘 | Chen, Xianjun Liu, Renmei Ma, Zhengcai Xu, Xiaopei Zhang, Haoqian Xu, Jianhe Ouyang, Qi Yang, Yi | 2016 | Cell Research2016，26，7： | 7 |
| 10 | Conductive grease synthesized using nanometer ATO as an additive显示文摘A new conductive grease was synthesized using a nanometer powder,i.e.,Sb doped SnO2(ATO),as an additive.The typical properties of this new conductive grease were investigated in detail.The results indicate that ATO can dramatically improve the dropping point and reduce contact resistance.The tribological properties of the new conductive grease were investigated using the MFT-R4000 reciprocating friction and wear tester.The tribol-test results indicate that ATO can dramatically improve the tribological properties of the grease.When the ATO concentration is 0.1wt%,the grease demonstrates the best friction reduction properties;when the concentration is 0.5wt%,the grease demonstrates the best anti-wear properties.The worn surfaces were observed and analyzed by scanning electron microscopy and energy-dispersive X-ray spectroscopy,and the friction mechanisms for the new conductive grease are proposed.The excellent tribological properties of the new conductive grease are attributed to the mechanical effect of ATO,and the film formed by Sn and Sb elements or metallic oxide deposited on worn surfaces during the friction process. | Xiangyu GE Yanqiu XIA Zongying SHU Xiaopei ZHAO | 2015 | Friction2015，3，1： | 6 |
| 11 | Scientific progress regarding neural regeneration in the Web of Science A 10-year bibliometric analysis显示文摘BACKGROUND:Neural regeneration following nerve injury is an emerging field that attracts extending interests all over the world.OBJECTIVE:To use bibliometric indexes to track studies focusing on neural regeneration,and to investigate the relationships among geographic origin,countries and institutes,keywords in the published articles,and especially focus on the region distribution,institution distribution,as well as collaborations in Chinese papers indexed in the Web of Science.METHODS:A list of neural regeneration studies was generated by searching the database of the Web of Science-Expanded using the term'Neural Regenera*'.Inclusive criteria:(1)articles in the field of neural regeneration;(2)fundamental research on animals,clinical trials and case reports;(3)article types:article,review,proceedings paper,note,letter,editorial material,discussion,book chapter;(4)year of publication:2003–2012;and(5)citation database:Science Citation Index-Expanded.Exclusive criteria:(1)articles requiring manual searching or with access only by telephone;(2)unpublished articles;and(3)corrections.RESULTS:A total of 4 893 papers were retrieved from the Web of Science published between 2003and 2012.The papers covered 65 countries or regions,of which the United States ranked first with1 691 papers.The most relevant papers were in the neurosciences and cell biology,and the keyword'stem cell'was the most frequent.In recent years,China showed a great increase in the number of papers.Over the entire 10 years,there were 922 Chinese papers,with Jilin University ranking first with 58 articles.Chinese papers were published in connection with many countries,including the United States,Japan,and the United Kingdom.Among the connections,the papers published by the Chinese and the American are 107,with the highest rate.With regard to funding,689 articles were funded from various projects,occupying 74.72%of the total amount.In these projects,National Foundation and Science and Technology programs were the majority.CONCLUSION:Our bibliometric analysis provides a historical perspective on the progress of neural regeneration research.At present,the number of articles addressing neural regeneration is increasing rapidly;however,through analysis of citations it is clear that there is a long way to go to improve the academic quality. | Yuntao Pan Yuhua Zhang Xiaopei Gao Jia Jia Jiping Gao Zheng Ma | 2013 | Neural Regeneration Research2013，8，36： | 5 |
| 12 | 胃食管反流病:内镜评估与治疗方面的革新显示文摘内镜技术的创新为胃食管反流病(GERD)的诊治带来了巨大进步。作为世界上最常见的胃肠疾病之一,GERD一直是内镜介入治疗的前沿。目前,GERD的初步诊断是基于症状和质子泵抑制剂(PPI)初期治疗有效,但这对治疗策略的指导价值有限。然而,内镜检查和病理活检可直接观察和判断食管的异常结构和病理生理损伤;同时,内镜治疗的出现给PPI治疗依从性较差或治疗反应不佳以及不适合行胃底折叠抗反流手术的患者提供了新的治疗选择。本综述对内镜检查和活检在经过恰当的抗反流药物治疗后持续存在GERD相关临床表现的患者中的应用情况进行了概述,并介绍了目前内镜治疗GERD的各项新技术及其优缺点。今后的研究需要对GERD患者进行分层研究,并力图阐明该疾病的主要病理生理机制。 | Sheng Chen Feng Du Changqing Zhong Caifang Liu Xiaoying Wang Yan Chen Gang Wang Xiaopei Gao Lu Zhang Lianyong Li Wei Wu | 2021 | Gastroenterology Report2021，9，5： | 4 |
| 13 | Prognostic value of interim ^(18)F-FDG PET/CT in diffuse large B-cell lymphoma显示文摘Objective: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease. The prognostic factor currently used is not accurate enough to predict the outcomes of patients with DLBCL. The prognostic significance of interim PET/CT in DLBCL remains controversial. The aim of this study is to determine the predictive value of interim 18F-FDG PET/CT after first-line treatment in patients with DLBCL. Methods: Thirty-two patients with DLBCL underwent baseline, interim and post-treatment 18F-FDG PET/CT scans. Imaging results were analyzed for the survival of patients via software SPSS 13.0, retrospectively. Results: Thirty-one of the 32 patients were treated with R-CHOP regimen, and interim 18F-FDG PET/CT of 24 patients was performed after 2 cycles of treatment. After a median follow-up period of 16.7 months, the 2-year progression-free survival (PFS) rates were significantly different between the groups above and below SUV max cut-off value of 2.5 (P=0.039). No significant differences were found in the 2-year PFS rates if SUV max cut-off values were set as 2.0 and 3.0, respectively (P=0.360; P=0.113). Conclusions: Interim PET/CT could predict the prognosis of DLBCL patients with the SUV max cut-off value of 2.5, but more clinical data should be concluded to confirm this conclusion. | Zhitao Ying Xuejuan Wang Yuqin Song Wen Zheng Xiaopei Wang Yan Xie Ningjing Lin Meifeng Tu Lingyan Ping Weiping Liu Lijuan Deng Chen Zhang Zhi Yang Jun Zhu | 2013 | Chinese Journal of Cancer Research2013，25，1： | 4 |
| 14 | Analysis of interprovincial trade embodied carbon emissions in Beijing-Tianjin-Hebei and surrounding provinces: based on constructed MRIO Model显示文摘The interprovincial trade embodied carbon emissions plays an important role in the national emission reduction target among China's provinces. Furthermore, it will affect the smooth start-up of the national carbon trade market as well as the implementation of targets in 2030 for dealing with the climate change. Based on constructed MRIO model, this paper analyzes the embodied carbon emission trade flows among Beijing, Tianjin, Hebei and surrounding regions such as Shanxi, Shaanxi, and Inner Mongolia. The results indicate that six provinces have formed different patterns of carbon trade balance, where Beijing, Tianjin, and Hebei provinces are in a deficit position, while the other three provinces are in a surplus position.Beijing, Tianjin, and Hebei have transferred part of the carbon emissions to the other three provinces, which shows greater heterogeneity among various provinces and provincial different sectors. On basis of the conclusions, this paper puts forward some suggestions on provincial decomposition, responsibility distribution, and provincial collaborative reduction for national emission reduction targets. | Jianhui Cong Qingyan Liu Jidong Kang Wenju Li Xiaopei Wang Man Li | 2017 | Chinese Journal of Population,Resources and Environment2017，15，1： | 4 |
| 15 | A recursive calculating algorithm for higher-order cumulants over sliding window and its application in speech endpoint detection显示文摘Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases,a recursive calculating algorithm for higher-order cumulants over a sliding window is proposed.Then it is applied to the speech endpoint detection.Furthermore,endpoint detection is carried out with the feature of energy.Experimental results show that both the computational efficiency and the robustness against noise of the proposed algorithm are improved remarkably compared with traditional algorithm.The average probability of correct point detection(Pc-point) of the proposed voice activity detection(VAD) is6.07%higher than that of G.729 b VAD in different noisy at different signal-noise ratios(SNRs)environments. | LUO Yaqin WU Xiaopei L Zhao PENG Kui GUI Yajun | 2015 | Chinese Journal of Acoustics2015，34，4： | 4 |
| 16 | Sea Experiments of the Underway Conductivity-Temperature-Depth Prototype Made in China显示文摘A new instrument for upper ocean survey, namely the UCTD (Underway Conductivity-Temperature-Depth), which combines some of the advantages of other underway instruments, is introduced in this paper. The Introduction section presents a description of the construction and function of the UCTD, and the experiments conducted in the South China Sea on board the R/V Dong Fang Hong 2 in July 2007 and August 2008. The UCTD system, with pressure and temperature sensors in the probe, is con- veniently portable, cost-effective and environment-friendly. It is hopefully suitable for future cruises. An intercomparison based on regressing with the experiment temperature data from both SeaBird plus911 CTD and the UCTD showed that the standard deviation is 0.88℃ and the correlation coefficient is 0.96, achieving the goals set for the current oceanography uses. In the hydrodynamic experiments, the descending velocities and depths were calculated for different ship speeds. A pulling test was designed with a tensiometer to measure the magnitude of the pull. The maximal tension of the line was found to be 66.2 kg, which is far lower than the bearing limit of the Hollow Spectra line. Finally, some improvement suggestions are put forward for future experiments and production. | SONG Xiangzhou LI Hui LIN Xiaopei CHEN Xueen GUO Xinshun TIAN Jiwei | 2009 | Journal of Ocean University of China2009，8，4： | 4 |
| 17 | Preparation and Structural Investigation of CuCl_2 Graphite Intercalation Compounds显示文摘特级的石墨粉末被在行星的球 milling 系统包含无水的 CuCI2 的球工厂 exfoliated 石墨准备。Nano 规模 CuCl2 石墨置闰混合物被加热无水的 CuCl2 和石墨 nanosheets 的混合物综合。扫描电子显微镜学,精力散的 X 光检查光谱学和高分辨率的传播电子显微镜学被执行描绘 stage-1 nano 规模 CuCI2 石墨置闰混合物的微观结构。在 nano 规模 CuCl2 石墨置闰混合物的领域墙和核心的结构和部件被描述。结果证明在混合的 CuCl2 的内容在 nano 规模 CuCl2 石墨置闰混合物的尺寸起一个关键作用。 | BIN Xiaopei CHEN Jiazang CAO Hong MA Enbao WANG Xuehua YUAN Jizhu | 2008 | Acta Geologica Sinica(English Edition)2008，82，5： | 4 |
| 18 | An Examination of the Predictability of Tropical Cyclone Genesis in High-Resolution Coupled Models with Dynamically Downscaled Coupled Data Assimilation Initialization显示文摘Predicting tropical cyclone(TC)genesis is of great societal importance but scientifically challenging.It requires fineresolution coupled models that properly represent air−sea interactions in the atmospheric responses to local warm sea surface temperatures and feedbacks,with aid from coherent coupled initialization.This study uses three sets of highresolution regional coupled models(RCMs)covering the Asia−Pacific(AP)region initialized with local observations and dynamically downscaled coupled data assimilation to evaluate the predictability of TC genesis in the West Pacific.The APRCMs consist of three sets of high-resolution configurations of the Weather Research and Forecasting−Regional Ocean Model System(WRF-ROMS):27-km WRF with 9-km ROMS,and 9-km WRF with 3-km ROMS.In this study,a 9-km WRF with 9-km ROMS coupled model system is also used in a case test for the predictability of TC genesis.Since the local sea surface temperatures and wind shear conditions that favor TC formation are better resolved,the enhanced-resolution coupled model tends to improve the predictability of TC genesis,which could be further improved by improving planetary boundary layer physics,thus resolving better air−sea and air−land interactions. | Mingkui LI Shaoqing ZHANG Lixin WU Xiaopei LIN Ping CHANG Gohkan DANABASOGLU Zhiqiang WEI Xiaolin YU Huiqin HU Xiaohui MA Weiwei MA Haoran ZHAO Dongning JIA Xin LIU Kai MAO Youwei MA Yingjing JIANG Xue WANG Guangliang LIU Yuhu CHEN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 4 |
| 19 | Prognostic value of pre-and post-transplantation 18F-fluorodeoxyglucose positron emission tomography results in non-Hodgkin lymphoma patients receiving autologous stem cell transplantation显示文摘Objective: High-dose chemotherapy(HDC) followed by autologous stem cell transplantation(ASCT) is the standard of care in the upfront or relapsed/refractory setting in some patients with non-Hodgkin lymphoma(NHL).However,a proportion of patients do not respond to ASCT.^(18)F-fluorodeoxyglucose(FDG) positron emission tomography(PET)/computed tomography(CT) has been widely used for staging,response evaluation,and prognosis prediction.Here,we investigated the prognostic role of PET/CT in NHL patients before and after ASCT.Methods: A retrospective study was conducted at Peking University Cancer Hospital.All NHL patients who underwent ASCT between March 2010 and July 2016 were identified.Patients who had PET/CT scan before and after ASCT were included.Deauville criteria(5-point scale) were used to interpret PET scans.Univariate and multivariate survival analyses were performed using Cox regression.The predictive value of PET scanning was estimated by comparing the area under the receiver operating characteristic(ROC) curve.Results: In total,79 patients were enrolled in this study.In univariate analysis,pre-and post-ASCT PET result was identified as prognostic factors for 3-year progression-free survival(PFS) and overall survival(OS).Patients with negative pre-ASCT PET result demonstrated significantly better PFS(84.2% vs.54.2%) and OS(89.2% vs.63.6%) than patients with positive pre-ASCT PET result.PFS(91.6% vs.25.3%) and OS(96.5% vs.36.8%) were also significantly different between patients with negative and positive post-ASCT PET result.Multivariate analysis also showed a significant association between survival and post-ASCT PET result.ROC analysis revealed that the predictive value of post-ASCT PET result was superior to that of pre-ASCT PET result alone.Combined pre-and post-ASCT PET result is better for predicting outcomes in patients with NHL receiving transplantation.Deauville criteria score >3 was identified as the best cutoff value for post-ASCT PET.Conclusions: Post-ASCT PET result was more important than pre-ASCT PET result in predicting outcomes for NHL patients who underwent ASCT.The prognostic significance can be improved when combining preASCT PET result with post-ASCT PET result.Deauville criteria can be used for interpreting PET scans in this scenario. | Zhitao Ying Lan Mi Xuejuan Wang Yuewei Zhang Zhi Yang Yuqin Song Xiaopei Wang WenZheng Ningjing Lin Meifeng Tu Yan Xie Lingyan Ping Chen Zhang Weiping Liu LijuanDeng Jun Zhu | 2017 | Chinese Journal of Cancer Research2017，29，6： | 3 |
| 20 | The investigation of internal solitary waves over a continental shelf-slope显示文摘Internal solitary waves(ISWs)always happen in marginal seas,where stable stratification exists.ISWs may carry large energy when they propagate and affect marine engineering constructions such as marine drilling platforms.Previous studies,including a large number of mooring observations and laboratory experiments,show the speed of ISWs will change when they pass by shelf slopes.Korteweg-de Vries(KdV)theory explain this phenomenon.In the paper,we use a laboratory experiment and a numerical model experiment to verify this theory.In the laboratory experiment,we injected two layers of water of different densities in a tank to simulate marine stratification and make ISWs.We use a CCD camera to record the whole process.The camera can take 16 photos per second.In the numerical experiment,we input the same original conditions as the laboratory one.The results of 18 different original conditions show the dimensionless factorδplays a key role in deciding the amplitudes and shapes of ISWs.The main conclusion also contains that small-amplitude waves match well with KdV theory while mKdV is better for largeamplitude waves.Whether the laboratory experiment or numerical experiment shows results with a high agreement.In future studies,we may use a numerical model with higher resolution to get analysis about phase speed and energy of ISWs. | MA Qian YUAN Chunxin LIN Xiaopei CHEN Xue’en | 2020 | Journal of Oceanology and Limnology2020，38，3： | 3 |
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