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| 1 | Review on the Research and Practice of Deep Learning and Reinforcement Learning in Smart Grids显示文摘Smart grids are the developmental trend of power systems and they have attracted much attention all over the world.Due to their complexities,and the uncertainty of the smart grid and high volume of information being collected,artificial intelligence techniques represent some of the enabling technologies for its future development and success.Owing to the decreasing cost of computing power,the profusion of data,and better algorithms,AI has entered into its new develop-mental stage and AI 2.0 is developing rapidly.Deep learning(DL),reinforcement learning(RL)and their combination-deep reinforcement learning(DRL)are representative methods and relatively mature methods in the family of AI 2.0.This article introduces the concept and status quo of the above three methods,summarizes their potential for application in smart grids,and provides an overview of the research work on their application in smart grids. | Dongxia Zhang Xiaoqing Han Chunyu Deng | 2018 | CSEE Journal of Power and Energy Systems2018，4，3： | 44 |
| 2 | Design strategies for two-dimensional material photodetectors to enhance device performance显示文摘Two-dimensional(2D)materials are intensively attractive for fabricating high sensitive photodetectors in terms of atomically thin flexible and ultrafast charge transport feature.Due to their atomically thin body,designing high performance detector requires new physical mechanisms and device structures.In this review,we classify design strategies and device structures into four categories depending on their physical mechanisms(photovoltaic effect,photoconductive effect,photothermoelectric effect or photobolometric effect,and surface plasma-wave-assisted effect),and summarize the device performances.Finally,future prospects and development direction for 2D material photodetectors are described.Those design strategies descriptions about photoelectronic detector provide a reference for high responsivity and fast response speed photodetector at broadband sensing in the future. | Jun Wang Jiayue Han Xiaoqing Chen Xinran Wang | 2019 | InfoMat2019，1，1： | 16 |
| 3 | Development of pyrF-based gene knockout systems for genome-wide manipulation of the archaea Haloferax mediterranei and Haloarcula hispanica显示文摘haloarchaea Haloferax mediterranei 和 Haloarcula hispanica 两个都是在领域 Archaea 的 polyhydroxyalkanoate 制片人,并且他们由于他们的唯一的基因、新陈代谢的特征为研究和生物工学正在变得逐渐地漂亮。加速他们的染色体级的基因、新陈代谢的分析,我们为这二 haloarchaea 开发了特定、高度有效的基因大美人系统。这些基因大美人系统作为选择标记和 uracil 与 pyrF 基因由自杀 plasmid 向量组成营养缺陷型的 haloarchaeon (pyrF ) 作为主人。为目标基因的在里面框架删除,带目标基因的 flanking 区域的自杀 plasmid 被变成相应 pyrF 主人。在没有双转线路的 uracil 和 counterselection 中等的 AS-168SY 上的单个转线路的集成 recombinants (突然发生在里面) 的积极选择以后有 5-fluoroorotic 酸(5-FOA ) 的切除 pyrF 的 recombinants (突然发生外面) ,目标基因大美人异种被 PCR 和南部的污点分析证实。我们由击倒把 phytoene synthase 编码为这些 haloarchaea 的 crtB 基因表明了这些系统的有效性。在结论,这些开发得好的猛烈系统将极大地加速这些 halophilic archaea 的功能的 genomic 研究。 | Hailong Liu Jing Han Xiaoqing Liu Jian Zhou Hua Xiang | 2011 | Journal of Genetics and Genomics2011，38，6： | 14 |
| 4 | Modeling experimental study on weathering-leaching of Emeishan basalt and its relation with metallogenesis显示文摘The Emeishan basalt has a high Cu background value (170×10-6 on average), and thus provides a ore-forming material source for copper ores. The collected samples were exposed in basalt lavas of the third segment of the Emeishan basalt eruptive cycle. By using a set of automatically cycling glass apparatuses, weathering-leaching experiments by three kinds of rainwater on the collected samples were carried out in the open system (at normal temperature and normal pressure). The analysis results showed that the most intensive export of Cu occurred under acidic rainwater-induced weathering-leaching conditions, almost 2-3 orders of magnitude the export of Cu by mod-ern air rainwater, and 1-2 orders of magnitude higher than the export of Cu by CO2 rainwater. In addition, the total amount of Zn, Cu, U, Ni and Sr exported by acidic rainwater are greater than 1%. All this indicates that copper in the Emeishan basalt provided the copper source for Cu mineralization at the contact between the basalt and the Maokou Formation limestone at the bottom. | WANG Fudong ZHU Xiaoqing HAN Tao LI Zengsheng | 2010 | Chinese Journal Of Geochemistry2010，29，2： | 6 |
| 5 | Unraveling a genetic roadmap for improved taste in the domesticated apple显示文摘Although taste is an important aspect of fruit quality, an understanding of its genetic control remains elusive in apple and other fruit crops. In this study, we conducted genomic sequence analysis of 497 Malus accessions and revealed erosion of genetic diversity caused by apple breeding and possible independent domestication events of dessert and cider apples. Signatures of selection for fruit acidity and size, but not for fruit sugar content, were detected during the processes of both domestication and improvement. Furthermore, we found that single mutations in major genes affecting fruit taste, including Ma1, MdTDT, and MdSOT2, dramatically decrease malate, citrate, and sorbitol accumulation, respectively, and correspond to important domestication events. Interestingly, Ma1 was identified to have pleiotropic effects on both organic acid content and sugar:acid ratio, suggesting that it plays a vital role in determining fruit taste. Fruit taste is unlikely to have been negatively affected by linkage drag associated with selection for larger fruit that resulted from the pyramiding of multiple genes with minor effects on fruit size. Collectively, our study provides new insights into the genetic basis of fruit quality and its evolutionary roadmap during apple domestication, pinpointing several candidate genes for genetic manipulation of fruit taste in apple. | Liao Liao Weihan Zhang Bo Zhang Ting Fang Xiao-Fei Wang Yarning Cai Collins Ogutu Lei Gao Gang Chen Xiaoqing Nie Jinsheng Xu Quanyan Zhang Yiran Ren Jianqiang Yu Chukun Wang Cecilia H.Deng Baiquan Ma Beibei Zheng Chun-Xiang You Da-Gang Hu Richard Espley Kui Lin-Wang Jia-Long Yao Andrew C.Allan Awais Khan Schuyler S.Korban Zhangjun Fei Ray Ming Yu-Jin Hao Li Li Yuepeng Han | 2021 | Molecular Plant2021，14，9： | 5 |
| 6 | Nitrogen and Sulfur Co-doped Porous Carbon Derived from ZIF-8 as Oxygen Reduction Reaction Catalyst for Microbial Fuel Cells显示文摘Nitrogen and sulfur co-doped porous nanocarbon (ZIF-C-N-S) catalyst was successfully synthesized derived from ZIF-8 and thiourea precursors.The electrochemical measurements indicate that the as-obtained ZIF-C-N-S catalyst exhibits higher electrocatalytic activity for oxygen reduction reaction (ORR) in alkaline electrolyte and superior durability-longer than commercial Pt/C catalyst.The enhancment of electrocatalytic activity mainly be come from the open pore structure,large specific surface area as well as the synergistic effect resulted from the co-doping of N and S atoms.In addition,the ZIF-C-N-S catalyst is also used as the air cathode catalyst in the microbial fuel cell (MFC) device.The maximum power density and stable output voltage of ZIF-C-N-S based MFC are 1315 mW/m2 and 0.48 V,respectively,which is better than that of Pt/C based MFC. | HAN Wuli YAN Xuemin JIANG Yu PING Mei DENG Xiaoqing ZHANG Yan | 2020 | Journal of Wuhan University of Technology(Materials Science)2020，35，2： | 4 |
| 7 | Distinct contribution of PD-L1 suppression by spatial expression of PD-L1 on tumor and non-tumor cells显示文摘Programmed cell death receptor 1(PD-1)and its ligand,PD-L1,are important immune checkpoint proteins.Although antibodies that block PD-1/PD-L1 have shown promising clinical efficacy in a subset of cancer patients,the detailed cellular and molecular mechanisms behind anti-PD-1 and anti-PD-L1 immunotherapy are not well defined.Specifically,the way in which PD-L1 contributes to immune suppression on tumor and non-tumor cells remains controversial.By selectively blocking PD-L1 on either tumor or non-tumor cells,we demonstrated that PD-L1 from both sources suppressed the anti-tumor T-cell response.Blocking PD-L1 on either tumor cells or non-tumor cells inhibited tumor growth and enhanced immune cell infiltration,as well as the tumor-specific T-cell response.Further,simultaneously blocking tumor-and non-tumor-derived PD-L1 maximized anti-tumor T-cell responses and demonstrated synergy.In addition,the relative contribution of PD-L1 on tumor and non-tumor cells to immune suppression depended on the PD-L1 expression level.Lastly,we found that the F4/80 receptor was involved in the anti-tumor effect of PD-L1 blockade.Taken together,our data indicate that PD-L1 on both tumor and non-tumor cells is critical for T-cell inhibition,which provides new directions for the optimization of PD-L1-blocking antibodies and the development of clinical biomarker strategies. | Xiaoqing Zhang Chen Cheng Jiyan Hou Xinyue Qi Xin Wang Ping Han Xuanming Yang | 2019 | Cellular & Molecular Immunology2019，16，4： | 3 |
| 8 | A post-GWAS confirming the genetic effects and functional polymorphisms of AGPAT3 gene on milk fatty acids in dairy cattle显示文摘Background: People are paying more attention to the healthy and balanced diet with the improvement of their living standards. Milk fatty acids(FAs) have been reported that they were related to some atherosclerosis and coronary heart diseases in human. In our previous genome-wide association study(GWAS) on milk FAs in dairy cattle, 83 genomewide significant single nucleotide polymorphisms(SNPs) were detected. Among them, two SNPs, ARS-BFGL-NGS-109493 and BTA-56389-no-rs associated with C18 index(P = 0.0459), were located in the upstream of 1-acylglycerol-3-phosphate O-acyltransferase 3(AGPAT3) gene. AGPAT3 is involved in glycerol-lipid, glycerol-phospholipid metabolism and phospholipase D signaling pathways. Hence, it was inferred as a candidate gene for milk FAs. The aim of this study was to further confirm the genetic effects of the AGPAT3 gene on milk FA traits in dairy cattle.Results: Through re-sequencing the complete coding region, and 3000 bp of 5′ and 3′ regulatory regions of the AGPA T3 gene, a total of 17 SNPs were identified, including four in 5′ regulatory region, one in 5′ untranslated region(UTR),three in introns, one in 3′ UTR, and eight in 3′ regulatory region. By the linkage disequilibrium(LD) analysis with Haploview4.1 software, two haplotype blocks were observed that were formed by four and 12 identified SNPs,respectively. Using SAS9.2, we performed single locus-based and haplotype-based association analysis on 24 milk FAs in 1065 Chinese Holstein cows, and discovered that all the SNPs and the haplotype blocks were significantly associated with C6:0, C8:0 and C10:0(P < 0.0001–0.0384). Further, with Genomatix, we predicted that four SNPs in 5′ regulatory region(g.146702957 G > A, g.146704373 A > G, g.146704618 A > G and g.146704699 G > A) changed the transcription factor binding sites(TFBSs) for transcription factors SMARCA3, REX1, VMYB, BRACH, NKX26, ZBED4, SP1, USF1, ARNT and FOXA1. Out of them, two SNPs were validated to impact transcriptional activity by performing luciferase assay that the alleles A of both SNPs, g.146704373 A > G and g.146704618 A > G, increased the transcriptional activities of AGPAT3 promoter compared with alleles G(P = 0.0004).Conclusions: In conclusion, our findings first demonstrated the significant genetic associations of the AGPAT3 gene with milk FAs in dairy cattle, and two potential causal mutations were detected. | Lijun Shi Xin Wu Yuze Yang Zhu Ma Xiaoqing Lv Lin Liu Yanhua Li Feng Zhao Bo Han Dongxiao Sun | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 3 |
| 9 | Sustainable management of Chinese grasslands—issues and knowledge显示文摘China has almost 400 Mhm^2 of grasslands,90% of which is considered degraded to varying degrees,on which 16 million herders depend for their livelihoods and many more indirectly, along the value-adding chain.Since 1950, average stocking rates across China have increased 4-fold. National policies have focused over recent decades on finding ways to rehabilitate the degraded grasslands, to sustain livestock production from them, and to improve the livelihoods of herder households, who are among the poorest people in China. A large collaborative program commenced in the early 2000 s to help find solutions to the sustainable management of grasslands.This paper summarizes key findings of many research projects, identifies where knowledge is weak and argues that the successful rehabilitation of grasslands will also require policies that provide incentives and support for herders as they move from a focus on survival to a focus on production of higher quality products, for which consumers are increasingly willing to pay. A key focus is to emphasize the improvement of animal production per head. When this is done, it naturally leads to lower stocking rates, which in turn provides the opportunities for grasslands to recover. Across a range of experiments, farm demonstrations and analyses using models, in Inner Mongolia and Gansu, a consistent result has been that a 50% reduction in stocking rates, improves net household income and starts the process of grassland rehabilitation.Rather than focusing on stocking rates, better management of grasslands could be achieved by maintaining the grasslands above critical values for herbage mass, values that help optimize botanical composition, reduce soil erosion, optimize animal growth rates and aid ecosystem functions. Managing to critical values for herbage mass is likely to be more effective than efforts to calculate sustainable stocking rates. An early summer rest is valuable for aiding grassland rehabilitation and summer productivity, but a total grazing ban(typically for 5 years)may not achieve its aims as evidence shows it may take 10–15 years to achieve a better grassland state. Lessdesirable plant species often increase in degraded grasslands that are rested and grazing can help manage those species. Surveys of herders indicate they have very mixed views on the benefits of total grazing bans that are unlikely to rehabilitate grasslands to an ideal botanical composition.The current objective is to work with grasslands that herders now have and optimize the existing composition.Grazing grasslands in winter results primarily in weight loss by animals and there is now evidence of how winter grazing reduces grassland growth in the next summer. It is better to keep animals in well-built sheds and feed them better, improved feeding through the cold months is required. In addition to the application of results from national programs designed to improve grasslands, it will be important to train herders as they move from survival to production, to foster the development of better markets for their livestock products, to devise better financial support for herder businesses and to revise land tenure arrangements so that herders can expand the area of land they graze on better terms than apply at present. | David KEMP Guodong HAN Fujiang HOU Xiangyang HOU Zhiguo LI Yi SUN Zhongwu WANG Jianping WU Xiaoqing ZHANG Yingjun ZHANG Xuyin GONG | 2018 | Frontiers of Agricultural Science and Engineering2018，5，1： | 3 |
| 10 | Ultra-stable silica-coated chiral Au-nanorod assemblies: Core-shell nanostructures with enhanced chiroptical properties显示文摘 | Bing Han Lin Shi Xiaoqing Gao Jun Guo Ke Hou Yonglong Zheng Zhiyong Tang | 2016 | Nano Research2016，9，2： | 3 |
| 11 | The LTR of endogenous retrovirus ev21 retains promoter activity and exhibits tissue specific transcription in chicken显示文摘Endogenous viruses integrate into the host genome and influence the expression of neighboring genes through their long terminal repeats (LTRs). In this study, we analyzed the promoter, enhancer and transcriptional activities of the chicken endogenous retrovirus ev21 LTR. The LTR was cloned into pGL3-basic and pGL3-promoter luciferase vectors in forward and reverse orientation separately. The luciferase activities were detected respectively in chicken embryonic fibroblast cell, human embryonic kidney cell line, human lung carcinoma cell line, Chinese hamster ovary cell line, and murine melanoma cell line. Relative luciferase activity analysis indicated that the ev21 LTR retained bi-directional promoter activity but no detectable enhancer activity in these cells. The constructs containing the LTR and F1 region show stronger promoter activity than the constructs containing only LTR. The transcriptional pattern of ev21 LTR varied in tissues of late feathering White Leghorn chicken at post-hatch day one. Skin exhibits the highest expression in the tissues examed. Collectively, our results indicate that the ev21 LTR exhibits tissue-type specific expression in White Leghorn chicken, and it also have regulatory potential. | LU XiaoQing HAN JinRun LIU XiaoFang LIN TongHui LI YuLin HU XiaoXiang LI Ning | 2009 | Chinese Science Bulletin2009，54，24： | 3 |
| 12 | Simulating experiment on the enrichment of precious metals in Lower Cambrian black shale series of Hunan and Guizhou provinces显示文摘Adsorption experiments were made at room temperature and neutral pH value on different types of min-erals associated with the Lower Cambrian black shale series polymetallic layers in Hunan and Guizhou provinces on nanometer-sized Pt colloids and PtCl42--bearing ionic solutions with an attempt to constrain the relationship between the different types of minerals in the polymetallic layers and the enrichment of platinum group elements (PGEs). Experimental results showed that the different types of minerals show strong selectivity to the adsorption of nano-meter-sized Pt colloids and PtCl42--bearing ionic solutions. Metallic sulfides, organic matter and clay minerals are the strong adsorbents of PGEs, while quartz, albite, muscovite and other silicate minerals show a week adsorbility to both of them. This phenomenon is well consistent with the geological fact that metallic sulfides, organic matter and clay minerals in the polymetallic layers of the black shale series are the major carrier minerals of PGEs, giving a thorough explanation to the mechanism of enrichment of previous metal elements. Adsorption may be a principal mechanism of enrichment of precious metal elements under lower temperature conditions. The presence of the aforementioned strong adsorbents is the good geochemical barriers for the enrichment of PGEs. | HAN Tao ZHU Xiaoqing LI Zengsheng | 2011 | Chinese Journal Of Geochemistry2011，30，3： | 2 |
| 13 | The Derivation Algebra and Automorphism Group of the Twisted N = 2 Superconformal Algebra显示文摘在这份报纸,推导代数学和扭曲的 N=2 superconformal 代数学的自守组是完全坚定的。 | Huanxia Fa Jianzhi Han Xiaoqing Yue | 2016 | Algebra Colloquium2016，23，3： | 2 |
| 14 | Metallogenic Model of Bauxite in Central Guizhou Province:an Example of Lindai Deposit显示文摘The bauxites in central Guizhou are hosted by the Lower Carboniferous Jiujialu Formation.Geochemistrial characteristics of the Lindai bauxite deposit indicate that the underlying Shilengshui Formation dolomite is the precursor rock of mineral resources.Weathering simulation experiments show that Si is most likely to migrate with groundwater,the migration rate of which is several magnitude higher than Al and Fe under nature conditions(pH=3–9).The neutral and acid non-reducing condition is the most conducive to the Al rich and Si removal,while the acid reducing conditions is the most conducive to the Al rich and Fe removal.In the process of bauxite formation,coal beds overlying the Al-bearing rock series or other rock formation rich in organic materials can produce acid reducing groundwater,which are important for the bauxite formation.Finally,propose the metallogenic model of the bauxite in central Guizhou Province and put forward three new words which are'original bauxite material','bauxite material'and'original bauxite'. | LING Kunyue ZHU Xiaoqing WANG Zhonggang HAN Tao TANG Haoshu CHEN Wenyi | 2013 | Acta Geologica Sinica(English Edition)2013，87，6： | 2 |
| 15 | Risk analysis of power systems for both real and reactive power显示文摘With the high penetration of renewable energy sources,the reliability of power systems becomes more vulnerable than ever because of the greater uncertainty and intermittence in power generation.Reactive power plays an important role in the power system reliability,because it is closely related to the system voltage stability and voltage collapse.However,reactive power-related reliability issues are seldom emphasized in conventional power reliability evaluations.This article investigates power system reliability of real and reactive power.Real and reactive power shortages and the associated voltage violations due to system failures are considered on reliability evaluation of power systems.A three-stage load-shedding technique for post contingencies is implemented to determine the contributions of real and reactive power on the system reliability and to find an optimal way to release network violation.The results provide the detailed information on power system planning and operation for system planners and operators from real and reactive power aspects. | Wenping QIN Peng WANG Xiaoqing HAN Fanhua MENG | 2013 | Journal of Modern Power Systems and Clean Energy2013，1，2： | 1 |
| 16 | Encapsulation of food ingredients 显示文摘 | Fereidoon Shahidi Han Xiaoqing | 1993 | Critical Review in Food Science and Nutrition1993，33，6： | 1 |
| 17 | Production and characteristics of protein hydrolysates from capelin (Mallo'tu villosus)显示文摘 | SHAHIDI F HAN Xiaoqing SYNOWIECKI J | | 0，，03： | 1 |
| 18 | Characterization of the immunogenicity and pathogenicity of malate dehydrogenase in Brucella abortus显示文摘 | Xiangan Han Yongliang Tong Mingxing Tian Xiaoqing Sun Shaohui Wang Chan Ding Shengqing Yu | 2014 | World Journal of Microbiology and Biotechnology2014，，7： | 1 |
| 19 | Effect of pH on rheology of aqueous Al_(2)O_(3)/SiC colloidal system显示文摘The rheological behavior of aqueous Al_(2)O_(3)/SiC suspensions at different pH values was investigated by rheological measurement.Experimental results showed that at pH=3-6,Al_(2)O_(3) and SiC particles have opposite surface charges,and the binary suspensions have lower viscosity than the unary suspensions at shear rates of 0-300 s^(-1).Furthermore,at pH=3-12,the stability of the Al_(2)O_(3) component seemed to dominate the overall rheological behavior of the Al_(2)O_(3)/SiC binary suspensions.The tendency mentioned above showed little variations in various ionic strengths,particle diameters and component fractions. | Xiaoqing ZHANG Yanli ZHANG Han CHEN Lucun GUO | 2014 | Journal of Advanced Ceramics2014，3，2： | 1 |
| 20 | A survey on wireless sensor network infrastructure for agriculture 显示文摘 | Yu Xiaoqing Wu Pute Han Wenting | 2013 | Computer Standards & Interfaces2013，35，1： | 1 |
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