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| 1 | Steps Toward Industry 5.0:Building“6S”Parallel Industries With Cyber-Physical-Social Intelligence显示文摘Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus on why and what is Industry 5.0 yet.In this paper,we define Industry 5.0from its philosophical and historical origin and evolution,emphasize its new thinking on virtual-real duality and human-machine interaction,and introduce its new theory and technology based on parallel intelligence(PI),artificial societies,computational experiments,and parallel execution(the ACP method),and cyber-physical-social systems(CPSS).Case studies and applications of Industry 5.0 over the last decade have been briefly summarized and analyzed with suggestions for its future development.We believe that Industry 5.0 of virtual-real interactive parallel industries has great potentials and is critical for building smart societies.Steps are outlined to ensure a roadmap that would lead to a smooth transition from CPS-based Industry 4.0 to CPSS-based Industry 5.0 for a better world which is Safe in physical spaces,S ecure in cyberspaces,Sustainable in ecology,Sensitive in individual privacy and rights,Service for all,and Smartness of all. | Xingxia Wang Jing Yang Yutong Wang Qinghai Miao Fei-Yue Wang Aijun Zhao Jian-Ling Deng Lingxi Li Xiaoxiang Na Ljubo Vlacic | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，8： | 4 |
| 2 | Single nucleotide polymorphism analysis of the encoding region of EX-FABP gene and its association with fattiness trait in chicken显示文摘Fattiness is an important parameter to estimate meat quality, which has high heritability. In this experiment, F2 chickens derived from Broilers crossing to Silky were used to study the effect of extracellular fatty acid inding protein (EX-FABP) gene on abdominal fat accumulation. Five exons and partial introns of the gene were amplified by six pairs of primers, and then single nucleotide polymorphisms (SNPs) were detected by single strand conformation polymorphism (SSCP) and subsequently confirmed by sequencing. There were four nucleotides variations found, T-C at 659, C-T at 924, CA-TG at 968 and C-T at 1985 respectively. The result of least square analysis suggests that the chickens with HH genotype defined by the third pair of primers have a lower abdominal fat weight and abdominal fat percentage than the chickens with other genotypes (GG, GI, GH and II). It implies that extracellular fatty acid binding protein gene could be a candidate locus or linked to a major gene that significantly affects abdominal fat traits in chicken. | WANG Qigui, LI Ning, HU Xiaoxiang, DENG Xuemei, LIAN Zhengxing,LI Hui and WU Changxin( National Laboratory for Agribiotechnology, China Agricultural University, Beijing 100094, China College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China College of Animal Science and Technology, China Agricultural University, Beijing 100094, China) | 2002 | Progress in Natural Science:Materials International2002，12，3： | 3 |
| 3 | Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China显示文摘Background:Although the incidence and clinical manifestations of pituitary apoplexy were reported by a few researches,the results are not consistent.This study aimed to explore the risk factors associated with an incidence of apoplexy in pituitary adenomas.Methods:The clinical information of 843 patients with pituitary adenoma from the Department of Neurological Surgery,1st Affiliated Hospital of Kunming Medical University,was reviewed.The incidence,clinical manifestation,and potential risk factors for pituitary apoplexy were analyzed by a case-control study.Results:In total,121 patients(14.4%)with macroadenoma were suffered from pituitary apoplexy.Headache,vomiting,and visual impairment are the top 3 symptoms for the pituitary apoplexy.Logistic regression results showed that the hypertension(hypertension vs non-hypertension OR=2.765,95%CI:1.41~5.416),tumor type(negative staining vs.positive staining,OR=1.501,95%CI:1.248~5.235),and tumor size(diameter>2 cm vs.diameter≤2 cm,OR=3.952,95%CI:2.211~7.053)are independent factors associated with pituitary apoplexy.Conclusion:Our results indicate that the risk factors for the incidence of pituitary apoplexy depend mainly on properties of the tumor itself(tumor size and pathologic type)and the blood pressure of patients. | Yao Li Yuan Qian Yisheng Qiao Xiaoxiang Chen Jiaotian Xu Chao Zhang Wei Wang Junjun Li Xingli Deng | 2020 | Chinese Neurosurgical Journal2020，6，4： | 3 |
| 4 | Dynamic monitoring of changes in endothelial cell-substrate adhesiveness during leukocyte adhesion by microelectrical impedance assay显示文摘到在发炎过程的 endothelial 房间的白血球的粘附导致 endothelial 房间底层粘着性的变化,并且这的理解变化将向我们提供发炎过程的重要信息。在这研究,我们使用了叫作在 endothelial 房间底层粘着性监视变化的电子传感器(RT-CES ) 系统以一种动态、量的方式由人的 monoblastic 房间线 U937 房间粘附导致了的即时房间的一个非侵略的生物传感器系统。这试金,基于房间底层阻抗读出,能由于 U937 房间粘附在房间底层粘着性监视短暂变化。对 endothelial 房间的 U937 房间粘附被 lipopolysaccharide (LPS ) 以一种剂量依赖者方式导致。尽管到 endothelial 房间的支持者 U937 房间的数字被标准试金验证,在 U937 房间的增加以后的 endothelial 房间的粘着性被 RT-CES 系统监视。而且,在 endothelial 房间的焦点的粘附 kinase 蛋白质减少和 F 肌动朊重新整理在 U937 房间的增加以后被观察。我们的结果显示到对待 LPS 的 endothelial 房间的 U937 房间的粘附把房间粘着性归结为底层,和如此的减小可能便于白血球的渗入。 | Yakun Ge Tongle Deng Xiaoxiang Zheng | 2009 | Acta Biochimica et Biophysica Sinica2009，41，3： | 2 |
| 5 | DOA estimation of incoherently distributed sources using importance sampling maximum likelihood显示文摘In this paper, an importance sampling maximum likelihood(ISML) estimator for direction-of-arrival(DOA) of incoherently distributed(ID) sources is proposed. Starting from the maximum likelihood estimation description of the uniform linear array(ULA), a decoupled concentrated likelihood function(CLF) is presented. A new objective function based on CLF which can obtain a closed-form solution of global maximum is constructed according to Pincus theorem. To obtain the optimal value of the objective function which is a complex high-dimensional integral,we propose an importance sampling approach based on Monte Carlo random calculation. Next, an importance function is derived, which can simplify the problem of generating random vector from a high-dimensional probability density function(PDF) to generate random variable from a one-dimensional PDF. Compared with the existing maximum likelihood(ML) algorithms for DOA estimation of ID sources, the proposed algorithm does not require initial estimates, and its performance is closer to CramerRao lower bound(CRLB). The proposed algorithm performs better than the existing methods when the interval between sources to be estimated is small and in low signal to noise ratio(SNR)scenarios. | WU Tao DENG Zhenghong HU Xiaoxiang LI Ao XU Jiwei | 2022 | Journal of Systems Engineering and Electronics2022，33，4： | 1 |
| 6 | Molecular Cloning and Single Nucleotide Polymorphism Detection of Buffalo DGAT1 Gene显示文摘 | Jing Yuan Jun Zhou Xuemei Deng Xiaoxiang Hu Ning Li | 2007 | Biochemical Genetics (-)2007，，7： | 1 |
| 7 | Overexpressing cellular repressor of E1A-stimulated genes protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt显示文摘 | Jie Deng Yaling Han Chenhui Yan XIaoxiang Tian Jie Tao Jian Kang Shaohua Li | 2010 | Apoptosis2010，，4： | 1 |
| 8 | Immunosuppressive therapy selectively modulates B-cell responses in patients with rheumatic and musculoskeletal diseases receiving the inactivated COVID-19 vaccine显示文摘Background:Immunosuppressive medication reduces the immunogenicity of the coronavirus disease 2019(COVID-19)vaccines in patients with rheumatic and musculoskeletal diseases(RMDs).However,the underlying mechanism remains unclear.The primary aim of our study was to dissect the impact of immunosuppressive medication on cellular and humoral immune responses in RMD patients receiving the inactivated COVID-19 vaccine.Methods:A total of 28 RMD patients and five healthy controls(HCs)receiving two doses of the inactivated COVID-19 vaccine(Sinovac-CoronaVac)were prospectively enrolled.Blood samples were collected before the primary vaccination(Week 0)and one week after the second vaccination(Week 5).Neutralizing antibody(nAb)titers and autoantibody titers were measured by a pseudovirus-based neutralization assay and enzyme-linked immunosorbent assay,respectively.CD4^(+)T-cell and CD19^(+)B-cell subsets and serum cytokines were analyzed by flow cytometry.Results:The inactivated COVID-19 vaccine was immunogenic in RMD patients and HCs after the second vaccination,but the nAb titers were lower in RMD patients than those in HCs.Only patients with systemic lupus erythematosus(SLE)had notably increased nAb titers.Remarkably,IgG^(+)CD27^(+),IgG^(+)IgG1^(+),and IgG^(+)IgG1^(−)B cells were reduced,whereas IgG−IgG1^(+)B cells,and total IgA and IgG titers were markedly increased.However,Tfh cell and Tfr cell subsets and cytokines produced by Tfh cells were not increased.The flare rate was low in RMD patients with comparable autoantibody titers,unchanged CD4^(+)T cell subsets and serum proinflammatory cytokines(interleukin[IL]-6,IL-17,interferon-γ,and tumor necrosis factor-α)after the second vaccination.Conclusions:Immunosuppressive therapy decreased the immunogenicity of the vaccine and maintained a low flare rate by selectively modulating B cell but not CD4^(+)T cell responses in RMD patients receiving the inactivated COVID-19 vaccine.Optimization of the treatment regimen might ensure a durable and robust COVID-19 vaccination response. | Rui Li Ruru Guo Jia Li Bing Zheng Ronghao Xu Xiaoyue Jiang Yingying Chen Guo Tang Qianqian Li Yixuan Li Jiaqi Feng Xiaoxiang Chen Ying Wang Shuang Ye Fang Du Liangjing Lu Jun Deng | 2023 | Rheumatology & Autoimmunity2023，3，2： | 0 |
| 9 | Chicken QTL mapping by multiplex PCR | HUANG Yinhua HU Xiaoxiang DENG Xuemei XU Weizhuo LI Ning FENG Jidong SUN Han WU Changxin | 2002 | Progress in Natural Science:Materials International2002，12，1： | 0 |
| 10 | A NOVEL ULTRA WIDEBAND MONOPOLE ANTENNA WITH BAND-NOTCHED CHARACTERISTICS显示文摘A simple and compact microstrip-fed Ultra WideBand(UWB) printed monopole antenna with band-notched characteristic is proposed in this paper.The antenna is composed of a square ring with a small strip bar,so that the antenna occupies about 7.69 GHz bandwidth covering 3.11~10.8 GHz with expected band rejection from 5.12 GHz to 5.87 GHz.A quasi-omnidirectional and quasi-sym-metrical radiation pattern is also obtained.This kind of band-notched UWB antenna requires no ex-ternal filters and thus greatly simplifies the system design of UWB wireless communication. | Deng Hongwei He Xiaoxiang Yao Binyan Zhou Yonggang | 2009 | Journal of Electronics(China)2009，26，2： | 0 |
| 11 | The gain of hydrogen peroxide resistance benefits growth fitness in mycobacteria under stress显示文摘 | Xiaojing Li Jun Tao Jiao Han Xinling Hu YulingChen Haiteng Deng Guangchun Zhang Xiaoxiang Hu Kaixia Mi | 2014 | Protein & Cell2014，5，3： | 0 |
| 12 | Approaches for Preventing the Male Sterility Fluctuation of Photo-thermo-sensitive Genie Male Sterile Lines in Rice显示文摘The male sterility fluctuation of photo-thermo-sensitive genic male sterile[P(T) GMS] lines induced by low air temperature is a key problem troubling the application of two-line system hybrid rice. The paper suggests to solve this problem by the breeding approaches, i. e, de-veloping low sterile critical temperauare P(T)GMS lines, herbicide resistant restorer lines, herbi-cide sensitive P(T)GMS lines and tetracycline- conditioned P(T)GMS lines to ensure the hybrid purity; and by the hybrid seed production techniques, i. e, taking the correct procedure of foun-dation seed production, the suitable district and season for hybrid seed production and the deep ir-rigation method against cold weather in high summer. | Xiao Guoying,Tang Li,Deng Xiaoxiang,and Yuan Longping China National Hybrid Rice Research and Development Center,Changsha,Hunan 410125 | 2001 | Hunan Agricultural Science & Technology Newsletter2001，2，1： | 0 |
| 13 | ICMPTend: Internet Control Message Protocol Covert Tunnel Attack Intent Detector显示文摘The Internet Control Message Protocol(ICMP)covert tunnel refers to a network attack that encapsulates malicious data in the data part of the ICMP protocol for transmission.Its concealment is stronger and it is not easy to be discovered.Most detection methods are detecting the existence of channels instead of clarifying specific attack intentions.In this paper,we propose an ICMP covert tunnel attack intent detection framework ICMPTend,which includes five steps:data collection,feature dictionary construction,data preprocessing,model construction,and attack intent prediction.ICMPTend can detect a variety of attack intentions,such as shell attacks,sensitive directory access,communication protocol traffic theft,filling tunnel reserved words,and other common network attacks.We extract features from five types of attack intent found in ICMP channels.We build a multi-dimensional dictionary of malicious features,including shell attacks,sensitive directory access,communication protocol traffic theft,filling tunnel reserved words,and other common network attack keywords.For the high-dimensional and independent characteristics of ICMP traffic,we use a support vector machine(SVM)as a multi-class classifier.The experimental results show that the average accuracy of ICMPTend is 92%,training ICMPTend only takes 55 s,and the prediction time is only 2 s,which can effectively identify the attack intention of ICMP. | Tengfei Tu Wei Yin Hua Zhang Xingyu Zeng Xiaoxiang Deng Yuchen Zhou Xu Liu | 2022 | Computers, Materials & Continua2022，，5： | 0 |
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