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| 1 | LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration显示文摘新兴的研究在少些在染色质水平,但是相对调整基因表示记录长非编码的 RNA (LncRNAs ) 的角色被知道他们怎么调整 DNA methylation。这里,我们识别 lncRNA, Dum (发展联系 pluripotency 2 (Dppa2 ) 在上游的有约束力的肌肉 lncRNA ) 在骨胳的 myoblast 房间。Dum 的表示动态地在 vitro 并且在 vivo 在 myogenesis 期间被调整。它被在 myoblast 区别之上有约束力的 MyoD transcriptionally 也导致。功能的分析证明它支持 myoblast 区别和导致损坏的肌肉新生。机械学地, Dum 被发现它的附近的基因到沉默, Dppa2,在通过招募的 cis Dnmt1, Dnmt3a 和 Dnmt3b。而且, intrachromosomal 在 Dum 地点和 Dppa2 倡导者之间循环为 Dum/Dppa2 相互作用是必要的。一起,我们识别了与 Dnmts 交往调整 myogenesis 的新奇 lncRNA。 | Lijun Wang Yu Zhao Xichen Bao Xihua Zhu Yvonne Ka-yin Kwok Kun Sun Xiaona Chen Yongheng Huang Ralf Jauch Miguel A Esteban Hao Sun Huating Wang | 2015 | Cell Research2015，25，3： | 34 |
| 2 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 3 | 美国油气管道维抢修应急响应程序显示文摘美国油气管道维抢修应急响应体系完备,主要体现在由联邦、州、地方政府机构、油气管道行业、公共安全以及其他组织机构的协调运行管理。介绍了建立管道维抢修应急响应程序遵循的主要法律法规和与之相关的立法机构。基于国家事故管理系统,国土安全部建立了管道维抢修应急响应程序,为具有不同事故原因、规模、地理位置或复杂性的事故提供了体系化处理方法,并基于社区规模、地理位置或自愿组织机构等进行人员和设备配置。以阿拉斯加州管道维抢修应急响应系统为例,详细介绍了应急响应队伍和人员的配置特点,应急反应资源的配备方式、影响因素和分布情况,可为国内油气管道维抢修应急响应工作的开展提供借鉴。 | 石蕾 郝建斌 郭正虹 He Xihua Li Jinwu Feng Maoqi | 2010 | 油气储运2010，29，12： | 18 |
| 4 | EXTENSION OF THE TOPSIS METHOD BASED ON PROSPECT THEORY AND TRAPEZOIDAL INTUITIONISTIC FUZZY NUMBERS FOR GROUP DECISION MAKING显示文摘Considering the decision maker's risk psychological factors and information ambiguity under uncertainty,a novel TOPSIS based on prospect theory(PT)and trapezoidal intuitionistic fuzzy numbers(nlFNs)for group decision making is investigated,in which the criteria values and the criteria weights take the form of TrIFNs.and weights of decision makers are unknown.Firstly,distance measures for TrIFNs ale used to induce value function under trapezoidal intuitionistic fuzzy environment.Secondly,the concepts of distance measures and trapezoidal intuitionistic fuzzy weighted averaging operator are employed to induce the weights of decision makers and thus the decision makers'options can be aggregated.Then the PT-based separation measures and relative closeness coefficient are defined and an algorithm for ranking alternatives under trapezoidal intuitionistic fuzzy environment is proposed.Finally,a numerical example further illustrates the practicality and effectiveness of the proposed TOPSIS method. | Xihua LI Xiaohong CHEN | 2014 | Journal of Systems Science and Systems Engineering2014，23，2： | 10 |
| 5 | Accurate studies on dissociation energies of diatomic molecules显示文摘The molecular dissociation energies of some electronic states of hydride and N2 molecules were studied using a parameter-free analytical formula suggested in this study and the algebraic method (AM) proposed recently. The results show that the accurate AM dissociation energies DeAM agree excellently with experimental dissociation energies Deexpt, and that the dissociation energy of an electronic state such as the 23Δg state of 7Li2 whose experimental value is not available can be predicted using the new formula. | SUN WeiGuo1, FAN QunChao1 & REN WeiYi1,2 1 Institute of Physics, Sichuan University, Chengdu 610065, China 2 Institute of Theoretical Physics, Xihua Normal University, Nanchong 637002, China | 2007 | Science China(Physics,Mechanics & Astronomy)2007，50，5： | 10 |
| 6 | 单肺通气在新生儿胸腔镜手术中的应用显示文摘目的探讨单肺通气在新生儿胸腔镜手术中的应用效果。方法择期行胸腔镜下食道重建术的先天性食道闭锁患儿60例,ASAⅡ或Ⅲ级,男31例,女29例,出生1-28d。随机均分为气管内插管组(A组)和支气管内插管组(B组)。麻醉诱导后,A组患儿在喉镜明视下完成气管插管,B组患儿在超纤细支气管内窥镜(Φ2.4mm)引导下完成普通气管导管的支气管内插管,其中左位主动脉弓者行左主支气管插管,反之,右位主动脉弓者行右主支气管插管,并于侧卧位后再次检查确认气管导管位置。记录两组患儿气管插管后5min(T_0)和人工气胸后5min(T_1)、10min(T_2)、30min(T_3)的HR、MAP、SpO_2、PETCO_2、RR、Pinsp、PEEP,并于上述各时点行动脉血气分析测得儿动脉血pH值、PaO_2、PaCO_2;评估两组患儿人工气胸后5min(T_1)、10min(T_2)的肺萎陷和手术野情况。结果 T_1-T_2时B组患儿SpO_2、PaO_2、肺萎陷和手术野评分均明显高于A组(P<0.05)。T_3时两组患儿SpO_2和PaO_2差异无统计学意义。T_0-T_3时两组患儿HR、MAP、PETCO_2、RR、Pinsp、PEEP、动脉血pH值、PaCO_2差异均无统计学意义。结论单肺通气用于新生儿胸腔镜手术,不仅安全可行,还可有效改善氧合,提高肺萎陷和手术野暴露程度。 | 胡华琨 李强 PENG Xihua XIAO Yu CHENG Liqun SHEN Shihui | 2017 | 江西医药2017，52，1： | 8 |
| 7 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 8 | Superatomic Aub clusters ligated by different N-heterocyclic carbenes and their ligand-dependent catalysis, photoluminescence, and proton sensitivity显示文摘We report herein a class of superatomic AU13 clusters stabilized by different N-heterocyclic carbenes(NHCs).The clusters show diverse metal surface structures,properties and functions as exemplified by:(1)the first anionic AU13 cluster[Au1g(NHC-1)sBr6],which has bulky NHC-1 ligands that lead to a rather open metal surface contributing to its high catalytic activity;(2)the tricationic cluster[Au13(NHC-2)sBr2]+which has bidentate,benzyl-rich NHC-2 ligands that make it ultra-stable and highly-luminescent,suitable for bio-imaging;and(3)by bearing two pyridyl groups on NHC-3,the dicationic cluster[Au:a(NHC-3)gClg]f+exhibits reversible and stable visible absorption and solubility responses to protonation/deprotonation cycles,making it a potential pH sensor(NHC-1=1,3-disopropylbenzimidazolin-ylidene;NHC-2=1,3-bis(1-benzyl-1H-benzimidazol-1-ium-yl)propane;NHC-3=1,3-bis(icolyI)benzimidazolin-ylidene).The study nicely demonstrates the importance of ligands in designing metal nanoclusters with desired functionalities. | Hui Shen Sijin Xiang Zhen Xu Chen Liu Xihua Li Cunfa Sun Shuichao Lin Boon K.Teo Nanfeng Zheng | 2020 | Nano Research2020，13，7： | 6 |
| 9 | Reduced Graphene Oxide/Carbon Nanofiber Based Composite Fabrics with Spider Web‑like Structure for Microwave Absorbing Applications显示文摘Composite fabrics with excellent microwave absorbing performance are highly desired.Herein,reduced graphene oxide/carbon nanofiber(rGO/CNF)based composite fabrics with spider web-like structure were successfully synthesized by electrostatic spinning technique.The spider web-like structure in the composite fabrics provides a connected network for efficient conductive loss of microwave energies.Magnetic loss benefits from the deposited nickel nanoparticles(Ni NPs)anchored in the carbon nanofibers.Meanwhile,the deposited thin polypyrrole(PPy)layers on the conductive network acts as a protective layer for Ni NPs as well as provides abundant interfaces for dissipating electromagnetic energies,which endow the composite fabrics stable microwave absorbing performance.Due to the synergistic effect of microwave absorb-ing mechanism,the maximum reflection loss(RL_(max))of the composite fabric at 6.72 GHz is-46.15 dB,and the effective absorption bandwidth(EAB)is as wide as 8.63 GHz(from 9.37 to 18 GHz).What's more,favorable mechanical and heat insulation properties of the composite fabrics reveal its multifunctional advantages.This rGO/CNF based composite fabric demonstrates a new direction for multifunctional and flexible microwave absorbing materials(MAMs). | Xihua Wang Jing Qin Jin Cui Li Huang Ye Yuan Yibin Li | 2022 | Advanced Fiber Materials2022，4，5： | 4 |
| 10 | Accurate studies on the full vibrational energy spectra and molecular dissociation energies for some electronic states of N_(2)molecule显示文摘It is usually very difficult to directly obtain molecular dissociation energy De and all accurate high-lying vibrational energies for most diatomic electronic states using modern experimental techniques or quantum theories, and it is also very difficult to give accurate analytical expression for diatomic molecular dissociation energy. This study proposes a new analytical formula for obtaining accurate molecular dissociation energy based on the LeRoy and Bernstein’s energy expression in dissociation limit. A set of full vibrational energy spectra for some electronic states of N2 molecule are studied using the algebraic method (AM) suggested recently, and the corresponding accurate molecular dissociation energies are evaluated using the proposed new formula and high-lying AM vibrational energies. The results show that the AM spectra and the new theoretical dissociation energies agree excellently with experimental data, and thereby providing a new physical approach to generating accurate dissociation energies for electronic states of diatomic molecules. | REN Weiyi1,2, SUN Weiguo1, HOU Shilin3 & FENG Hao4 1. Institute of Physics, College of Chemical Engineering, Sichuan University, Chengdu 610065, China 2. Institute of Theoretical Physics, Xihua Normal University, Nanchong 637002, China 3. Department of Physics, China Oceanography University, Qingdao 266003, China 4. College of Physics, Sichuan University, Chengdu 610065, China | 2005 | Science China(Physics,Mechanics & Astronomy)2005，48，4： | 4 |
| 11 | Analysis of Coupling between Soil and Water Conservation and Economic-social Development显示文摘The coupling relation exists in water and soil conser-vation and economic-social development. The article analyses the relation of soil and water conservation and economic-social development stages as well as the coupling analytical method. Then calculates the expecting income by dispersing Markov decision and calculates the correlation coefficient and the re-lationship degree. The article obtains the relationship of soil and water conservation investments and all kinds of incomes. Finally, it analyzes the important meaning in socio-economic development of water and soil conservation. | Sun Xihua Zhang Daimin Wan Han Chen Tingting Yan Fujiang | 2009 | Chinese Journal of Population,Resources and Environment2009，7，1： | 4 |
| 12 | Effects of ammonium and nitrate on encystment and growth of Scrippsiella trochoidea显示文摘To avoid unfavorable environmental conditions, Scrippsiella trochoidea is capable of forming a resting cyst in the process of growth. In the present study,we investigated the effects of nitrate and ammonium on the growth and encystment of S. trochoidea. We incubated S.trochoidea in modified f/2 media without nitrogen and silicate in flasks. The flasks were divided into two groups.Nitrate was added as a nitrogen source in the first group,and ammonium was added in the second group. The concentrations of the nitrogen compounds were 0, 10, 30, 60,and 90 lmol/L. The results indicate that NO3--N favors cell growth, and the cultures with a higher concentration of NO3--N were ineffective at forming cysts. In contrast,NH4--N promoted cell growth and cyst formation. At similar concentrations as NO3--N, NH4--N had a toxic effect on cell growth and increased the cyst formation ratio.Thus, the NH4--N concentration is an important factor for controlling encystment. We believe that the impact of NH4--N in inducing cyst formation may be a useful feedback mechanism in ecological systems. | Zhifu Wang Zhiming Yu Xiuxian Song Xihua Cao Yue Zhang | 2014 | Chinese Science Bulletin2014，59，33： | 4 |
| 13 | 鼓膜实验法测试薄膜基体界面结合强度的进展显示文摘评述了用鼓膜实验方法测试薄膜与基体界面结合强度的现状和最新进展,分析了该方法针对圆孔、膜内无残余应力柔性膜试样和矩形孔或圆孔、膜内有残余应力试样(薄膜为柔性膜或刚性膜)所用解析解力学模型建立的薄膜力学性能假设前提条件、能量平衡思路和推导过程.介绍了用硅微技术制备Si基体试样的过程,指出了制备方法和解析解力学模型的特点及所存在的问题.给出了该实验方法的应用实例,指出了需要解决非硅基体的制样和薄膜塑性变形阶段力学模型等问题. | 任凤章 郑茂盛 刘平 贾淑果 JU Xihua 马战红 祝要民 | 2006 | 材料研究学报2006，20，4： | 3 |
| 14 | Optical Waveguide Switches Employing Total-Internal-Reflection (TIR) Effect (Invited Paper)显示文摘In this paper, our recent research work on the total-internal-reflection optical switch is presented. The thermo-optic effect of polymeric materials and the photon-induced carrier effect of GaAlAs/GaAs are used in our devices. | Minghua Wang, Jianyi Yang, Xiaoqing Jiang, Xihua Li (Dept. of Information & Electronics Engineering, Zhejiang University, Hangzhou 310027, China) | 2003 | 光学学报2003，23，S1： | 3 |
| 15 | Prediction on dispersion in elastoplastic unsaturated granular media显示文摘This study focuses on the propagation of the plane wave in the elastoplastic unsaturated granular media,and the wave equations and dispersion equations are derived for the media under the framework of Cosserat theory.Due to symmetry,five different wave modes are considered and predicted for the elastoplastic unsaturated granular media based on the Cosserat theory,including two longitudinal waves,one rotational longitudinal wave and two coupled transverse–rotational transverse waves.The correspondence is discussed between these Cosserat wave modes and the classical wave modes.Based on the dispersion equations,the dispersion behaviors are obtained for the five Cosserat wave modes.The results indicated that the different stress-strain stages,including the elastic,hardening and softening stages,have obvious effect on the dispersion behaviors of the Cosserat wave modes. | Chenxi Xiu Xihua Chu Jiao Wang | 2020 | Theoretical & Applied Mechanics Letters2020，10，2： | 3 |
| 16 | Nano-and microphytoplankton community characteristics in brown tide bloom-prone waters of the Qinhuangdao coast,Bohai Sea, China显示文摘Since 2009, the newly recorded species Aureococcus anophagefferens has successively induced brown tides in the Qinhuangdao coastal waters of the Bohai Sea. Here, we focus on the phytoplankton community structure in this region and try to point out the biological background characteristics of the outbreaks of successive brown tides. We analyzed species composition,cell abundance, diversity indices and size-fractionated chlorophyll a(Chl-a) concentration monthly from March 2013 to January2014. The phytoplankton community, as observed by microscopy, underwent succession from nano-celled chained diatoms to dinoflagellates in the spring and summer, and then to micro-celled diatoms and nano-celled chained diatoms as the most prominent groups in the subsequent autumn and winter. Canonical correspondence analysis revealed that changes in the abundance of diatoms were related to nutrient availability, especially of nitrogen, while water temperature was the crucial factor influencing the abundance of dinoflagellates and A. anophagefferens. Considering the contribution of nano-celled chained species to the micro-sized Chl-a,small phytoplankton(<20 μm) composed the majority of total Chl-a and were generally abundant during our study. Abundant and diverse small phytoplankton seemed to serve as a background or seedbank for the formation of blooms of A. anophagefferens and other small-celled algae. | XU Xin YU ZhiMing HE LiYan CHENG FangJin CAO XiHua SONG XiuXian | 2017 | Science China Earth Sciences2017，60，6： | 3 |
| 17 | Improved method for zero-energy mode suppression in peridynamic correspondence model显示文摘The peridynamic correspondence model provides a general formulation to incorporate the classical local model and,therefore,helps to solve mechanical problems with discontinuities easily.But it suffers from zero-energy mode instability in numerical implementation due to the approximation of deformation gradient tensor.To suppress zero-energy modes,previous stabilized methods were generally more based on adding a supplemental force state derived from bond-based peridynamic theory,which requires a bond-based peridynamic micro-modulus.In this work,we present an improved stabilized method where the stabilization force state is derived directly from the peridynamic correspondence model.Hence,the bond-based peridynamic micro-modulus is abandoned.This improved method needs no extra constant to control the magnitude of stabilization force state and it is suitable for either isotropic or anisotropic materials.Several examples are presented to demonstrate its performance in simulating crack propagation,and numerical results show its efficiency and effectiveness. | Ji Wan Zhuang Chen Xihua Chu Hui Liu | 2019 | Acta Mechanica Sinica2019，35，5： | 3 |
| 18 | Covert wireless communication using massive optical comb channels for deep denoising显示文摘Covert wireless communications are unprecedentedly vital for security and privacy of individuals,government,and military bodies.Besides encryption,hiding signal transmission deeply under noise background highly proliferates the covertness in the physical layer.A deep signal hiding leads to a low interception probability at the interceptor but a poor data recovery at the receiver.To ensure both high covertness and high-fidelity recovery,massive and dense optical comb channels are utilized for deep denoising through the analog spectrum convolution.Using an external modulation-based optical frequency comb(OFC)and a single detection branch,the available optical comb channels can sustainably scale up by breaking or greatly mitigating physical bottlenecks on immense hardware and spectrum requirements.Thus,a striking signal-to-noise ratio(SNR)rise can be achieved for deep denoising.Combination of 1024 comb channels(the first parallel comb channel number beyond 1000)and the analog spectrum convolution enable a record SNR enhancement of 29 dB for a microwave signal with a 10.24 GHz bandwidth and a 10 Mbit/s data rate,which is deeply hidden below the in-band noises by 18 dB or even 30 dB in both the frequency and time domains.This method opens a new avenue for covert communications. | XIANGLEI YAN XIHUA ZOU PEIXUAN LI WEI PAN LIANSHAN YAN | 2021 | Photonics Research2021，9，6： | 3 |
| 19 | Rock slope stability evaluation in static and seismic conditions for left bank of Jinsha River Bridge along Lijiang-Xamgyi'nyilha railway, China显示文摘Jinsha River Bridge is located along the Lijiang-Xamgyi'nyilha railway on the southeastern Tibet plateau; it is an area with a high prevalence of earthquakes. The bridge abutments were designed to be constructed in river bank slopes, where rocks are controlled by two sets of joint planes that significantly influence the stability of the left bank slope. According to the engineering-geological conditions and the characteristics of discontinuities, strength properties of the rock mass were obtained based on Barton model and direct shear test. Numerical analyses were performed using FLAC3D software to examine the slope's response to seismic loading. Then in order to evaluate the damage trends of the rock mass under the different loading conditions, a calculation model based on the geological parameters and slope stability was simulated and analyzed using the discrete element numerical simulation program UDEC (Universal Distinct Element Code), and the effect of degradation of discontinuities on the slope stability was investigated. The results show that the destruction of rock mass under the gravity, bridge foundation, and seismic load are mainly concentrated within 30 m depth of slope, and the slope under loading may slide along joint planes. In addition, the dynamic analysis by amplification of the input loading indicates that instability occurs to the bank slope at a height of about 200 m, and rock blocks will fail under seismic load. Therefore, to prevent the slope from deformation under the engineering loading and strong earthquakes, the bridge foundation should be strengthened. | Zhiming ZHAO Guang WU Esamaldeen ALI Xihua WANG Chuan KOU | 2012 | Journal of Modern Transportation2012，20，3： | 3 |
| 20 | A New Method of Establishing Orthotopic Bladder Transplantable Tumor in Mice显示文摘<正>Objective The present study aims to find a convenient,rapid,and stable method to establish bladder tumor in mice. Methods Female Balb/C-nu-nu nude mice(or female T739 mice) were narcotized by sodium pentobarbital at a dosage of 60 mg/ kg.The stylet of the 24# venous retention needles was bent in a 5°to 7°angle at a distance of 15 mm from the needlepoint to form a circle with 2.61 mm to 3.66 mm radius when the stylet is rotated.The pipe casing was lubricated with liquid paraffin,and inserted into the bladder cavity.The drift angle stylet was inserted into the pipe casing slowly,rotated for five times,and then pulled out.A cell suspension(0.1 mL) of approximately 1×10~6 T24 cells(or BTT cells) was then injected immediately. Results A total of 60 T739 mice and 60 Balb/C-nu-nu nude mice were inoculated with BTT cells and T24 cells,respectively.The bladder tumor incidence and the average survival time of the tumor-bearing mice were 100%and(26.69±9.24) d and 100%and (34.59±9.8) d for the T739 mice and Balb/C-nu-nu nude mice,respectively. Conclusions Using the drift angle stylet to injure the mucous membrane of the urinary bladder can establish a stable bladder transplantable tumor model in mice. | Xi-hua Yang Lian-sheng Ren Guo-ping Wang Li-li Zhao Hong Zhang Zhen-guo Mi Xihua Bai | 2012 | Clinical oncology and cancer resexreh2012，9，4： | 3 |
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