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| 1 | Dispersion stability of thermal nanofluids显示文摘Thermal nanofluids, the engineered fluids with dispersed functional nanoparticles, have exhibited extraordinary thermophysical properties and added functionalities, and thus have enabled a broad range of important applications. The poor dispersion stability of thermal nanofluids, however, has been considered as a longexisting issue that limits their further development and practical application. This review overviews the recent efforts and progresses in improving the dispersion stability of thermal nanofluids such as mechanistic understanding of dispersion behavior of nanofluids, examples of both water-based and oil-based nanofluids,strategies to stabilize nanofluids, and characterization techniques for dispersion behavior of nanofluids. Finally,on-going research needs, and possible solutions to research challenges and future research directions in exploring stably dispersed thermal nanofluids are discussed. | Fan Yu Yingying Chen Xingbo Liang Jiale Xu Chiahsun Lee Qi Liang Peng Tao Tao Deng | 2017 | Progress in Natural Science:Materials International2017，27，5： | 5 |
| 2 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 3 | Dual-specificity phosphatase 6 (Dusp6), a negative regulator of FGF2/ERK1/2 signaling, enhances 17β-estrodial-induced cell growth in endometrial adenocarcinoma cell显示文摘 | Hui Zhang Qiufen Guo Chong Wang Lei Yan Yibing Fu Mingjun Fan Xingbo Zhao Mingjiang Li | 2013 | Molecular and Cellular Endocrinology (-)2013，，1： | 1 |
| 4 | Dual-specificity phosphatase 6 (Dusp6), a negative regulator of FGF2/ERK1/2 signaling, enhances 17β-estrodial-induced cell growth in endometrial adenocarcinoma cell显示文摘 | Hui Zhang Qiufen Guo Chong Wang Lei Yan Yibing Fu Mingjun Fan Xingbo Zhao Mingjiang Li | 2013 | Molecular and Cellular Endocrinology (-)2013，，1： | 1 |
| 5 | Preparation and Optimization of Mix ratio for C50T Girder Manufactured Sand and Concrete显示文摘Considering actual construction conditions of Binchuan-Heqing Highway,this paper provides the C50 mix ratio conforming to engineering requirements by strictly controlling the quality of raw materials,optimizing the design of mix ratio scientifically,preparing superior C50 concrete 0 with manufactured sand,and optimizing the concrete mix ratio based on the adjustment of fly ash replacement,water-cement ratio,polycarboxylate-type water reducer mixing amount,sand ratio,etc.The result indicates that,the water-cement ratio has a great influence on the concrete strength,and if the ratio of coal ash is high in the binding material,the early compressive strength of the concrete will increase slowly. | Honghong Ye Delin Zeng Yong Yang Xingbo Fan Wei Wang Pingbo Zao Zhusheng Yang | 2021 | Frontiers Research of Architecture and Engineering2021，4，2： | 0 |
| 6 | High-quality genome assembly and pan-genome studies facilitate genetic discovery in mung bean and its improvement显示文摘Mung bean is an economically important legume crop species that is used as a food,consumed as a vegetable,and used as an ingredient and even as a medicine.To explore the genomic diversity of mung bean,we assembled a high-quality reference genome(Vrad_JL7)that was479.35 Mb in size,with a contig N50 length of 10.34 Mb.A total of 40,125 protein-coding genes were annotated,representing96.9%of the genetic region.We also sequenced 217 accessions,mainly landraces and cultivars from China,and identified 2,229,343 high-quality single-nucleotide polymorphisms(SNPs).Population structure revealed that the Chinese accessions diverged into two groups and were distinct from non-Chinese lines.Genetic diversity analysis based on genomic data from 750 accessions in 23 countries supported the hypothesis that mung bean was first domesticated in south Asia and introduced to east Asia probably through the Silk Road.We constructed the first pan-genome of mung bean germplasm and assembled 287.73 Mb of non-reference sequences.Among the genes,83.1%were core genes and 16.9%were variable.Presence/absence variation(PAV)events of nine genes involved in the regulation of the photoperiodic flowering pathway were identified as being under selection during the adaptation process to promote early flowering in the spring.Genomewide association studies(GWASs)revealed 2,912 SNPs and 259 gene PAV events associated with 33 agronomic traits,including a SNP in the coding region of the SWEET10 homolog(jg24043)involved in crude starch content and a PAV event in a large fragment containing 11 genes for color-related traits.This high-quality reference genome and pan-genome will provide insights into mung bean breeding. | Changyou Liu Yan Wang Jianxiang Peng Baojie Fan Dongxu Xu Jing Wu Zhimin Cao Yunqing Gao Xueqing Wang Shutong Li Qiuzhu Su Zhixiao Zhang Shen Wang Xingbo Wu Qibing Shang Huiying Shi Yingchao Shen Bingbing Wang Jing Tian | 2022 | Plant Communications2022，3，6： | 0 |
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