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1An NIR photothermal-responsive hybrid hydrogel for enhanced wound healing显示文摘Moderately regulating vascularization and immune microenvironment of wound site is necessary to achieve scarless wound healing of the skin.Herein,we have prepared an angiogenesis-promoting and scar-preventing band-aid with a core-shell structure,that consists of MXene-loaded nanofibers(MNFs)as the core and dopamine-hyaluronic acid hydrogel(H)as the shell(MNFs@V-H@DA)to encapsulate a growth factor(vascular endothelial growth factor,VEGF,abbreviated as V)and H2S donor(diallyl trisulfide,DATS,abbreviated as DA).The continuous release of DA from this system produced H2S,which would successfully induce macrophages to polarize into M2-lile phenotype,regulating the immune microenvironment and inhibiting an excessive inflammatory response at the wound sites.It is conducive to the proliferation of skin cells,facilitating the wound healing.In addition,an appropriate amount of VEGF can be released from the MXene nanofibrous skeleton by adjusting the time of near-infrared(NIR)light exposure,preventing excessive neovascularization and extracellular matrix deposition at the wound sites.Collectively,this NIR photothermal-responsive band-aid achieved scarless wound healing through gradient-controlled vascularization and a related immune sequential reaction of damaged skin tissue.Lin Jin Xiaoqing Guo Di Gao Yan Liu Jiahua Ni Zhiming Zhang Yiqiao Huang Guibin Xu Zhe Yang Xingcai Zhang Xianhan Jiang 2022Bioactive Materials2022,7,10:4
2Growth of covellite crystal onto azurite surface during sulfurization and its response to flotation behavior显示文摘In this work,the growth of copper sulfide crystal onto azurite surfaces during sulfurization and its response to flotation are investigated.Filed emission scanning electron microscopy-energy dispersive X-ray spectroscopy(FESEM) and X-ray diffraction(XRD) studies confirmed that the sulfurization of azurite is not limited to the mineral surface,but rather penetrates into the bulk to form covellite crystal(synCuS),creating favorable conditions for the stable adsorption of xanthate and greatly promoting the azurite flotation.Additionally,as demonstrated by X-ray photoelectron spectroscopy(XPS) and time of flight secondary ion mass spectrometry(TOF-SIMS) analyses,a redox reaction occurred during this process,and Cu(Ⅱ) onto the mineral surface was reduced to Cu(Ⅰ).Correspondingly,reduced S^(2-) was oxidized to(S_(2))^(2-),(S_n)^(-2),and even to deeper oxidation state S~0,(S_(x)O_(y))^(n-) and SO_(4)^(2-).Excess sodium sulfide strengthens copper sulfide to form onto the azurite surface,and provides enough raw material for crystal copper sulfide to grow,resulting in the formation of 'flake-like' covellite with a better crystallinity.However,the floatability of azurite decreased dramatically under this condition,because the generated massive colloidal copper sulfide in flotation pulp deteriorates the flotation environment,resulting in a decreased effective adsorption of collector onto azurite surfaces.Jinpeng Cai Peilun Shen Dianwen Liu Xiaolin Zhang Jianjun Fang Chao Su Xingcai Yu Jiangli Li Han Wang 2021International Journal of Mining Science and Technology2021,31,6:4
3Ca^(2+)-supplying black phosphorus-based scaffolds fabricated with microfluidic technology for osteogenesis显示文摘Effective osteogenesis remains a challenge in the treatment of bone defects.The emergence of artificial bone scaffolds provides an attractive solution.In this work,a new biomineralization strategy is proposed to facilitate osteogenesis through sustaining supply of nutrients including phosphorus(P),calcium(Ca),and silicon(Si).We developed black phosphorus(BP)-based,three-dimensional nanocomposite fibrous scaffolds via microfluidic technology to provide a wealth of essential ions for bone defect treatment.The fibrous scaffolds were fabricated from 3D poly(L-lactic acid)(PLLA)nanofibers(3D NFs),BP nanosheets,and hydroxyapatite(HA)-porous SiO2 nanoparticles.The 3D BP@HA NFs possess three advantages:i)stably connected pores allow the easy entrance of bone marrow-derived mesenchymal stem cells(BMSCs)into the interior of the 3D fibrous scaffolds for bone repair and osteogenesis;ii)plentiful nutrients in the NFs strongly improve osteogenic differentiation in the bone repair area;iii)the photothermal effect of fibrous scaffolds promotes the release of elements necessary for bone formation,thus achieving accelerated osteogenesis.Both in vitro and in vivo results demonstrated that the 3D BP@HA NFs,with the assistance of NIR laser,exhibited good performance in promoting bone regeneration.Furthermore,microfluidic technology makes it possible to obtain high-quality 3D BP@HA NFs with low costs,rapid processing,high throughput and mass production,greatly improving the prospects for clinical application.This is also the first BP-based bone scaffold platform that can self-supply Ca^(2+),which may be the blessedness for older patients with bone defects or patients with damaged bones as a result of calcium loss.Zhanrong Li Xingcai Zhang Jiang Ouyang Dandan Chu Fengqi Han Liuqi Shi Ruixing Liu Zhihua Guo Grace X.Gu Wei Tao Lin Jin Jingguo Li 2021Bioactive Materials2021,6,11:4
4A facile and general method for synthesis of antibiotic-free protein-based hydrogel:Wound dressing for the eradication of drug-resistant bacteria and biofilms显示文摘Antibacterial protein hydrogels are receiving increasing attention in the aspect of bacteria-infected-wound healing. However, bacterial drug resistance and biofilm infections lead to hard healing of wounds, thus the construction of biological agents that can overcome these issues is essential. Here, a simple and universal method to construct antibiotic-free protein hydrogel with excellent biocompatibility and superior antibacterial activity against drug-resistant bacteria and biofilms was developed. The green industrial microbicide tetrakis (hydroxymethyl) phosphonium sulfate (THPS) as cross-linking agent can be quickly cross-linked with model protein bovine serum albumin (BSA) to form antibacterial hydrogel through simple mixing without any other initiators, subsequently promoting drug-resistance bacteria-infected wound healing. This simple gelatinization strategy allows at least ten different proteins to form hydrogels (e.g. BSA, human serum albumin (HSA), egg albumin, chymotrypsin, trypsin, lysozyme, transferrin, myohemoglobin, hemoglobin, and phycocyanin) under the same conditions, showing prominent universality. Furthermore, drug-resistance bacteria and biofilm could be efficiently destroyed by the representative BSA hydrogel (B-Hydrogel) with antibacterial activity, overcoming biofilm-induced bacterial resistance. The in vivo study demonstrated that the B-Hydrogel as wound dressing can promote reepithelization to accelerate the healing of methicillin-resistant staphylococcus aureus (MRSA)-infected skin wounds without inducing significant side-effect. This readily accessible antibiotic-free protein-based hydrogel not only opens an avenue to provide a facile, feasible and general gelation strategy, but also exhibits promising application in hospital and community MRSA disinfection and treatment.Jiang Ouyang Qingyue Bu Na Tao Mingkai Chen Haijun Liu Jun Zhou Jinggong Liu Bo Deng Na Kong Xingcai Zhang Tianfeng Chen Yihai Cao Wei Tao 2022Bioactive Materials2022,7,12:2
5Research Progress of Bactrocera(Zeugodacus) scutellata(Hendel)(Diptera: Tephritidae)显示文摘The stripped fruit fly,Bactrocera( Zeugodacus) scutellata( Hendel),is one of the most dangerous quarantine insect pests in China. Due to its wide distribution and heavy damage,it has caused serious economic losses in fruit and vegetable production in China. This paper assembles research progresses in morphological characteristics,classification status,host ranges,geographical distribution,population dynamics,molecular ecology and biology of B. scutellata,and put forward the following research prospects as well.Jin Yan Liu Xiaofei He Xingcai Ye Hui 2015Plant Diseases and Pests2015,6,3:2
6Projected Changes in Extreme High Temperature and Heat Stress in China显示文摘High temperature accompanied with high humidity may result in unbearable and oppressive weather. In this study,future changes of extreme high temperature and heat stress in China's Mainland are examined based on daily maximum temperature(T_x) and daily maximum wet-bulb globe temperature(T_w). T_w has integrated the effects of both temperature and humidity. Future climate projections are derived from the bias-corrected climate data of five general circulation models under the Representative Concentration Pathways(RCPs) 2.6 and 8.5 scenarios. Changes of hot days and heat waves in July and August in the future(particularly for 2020-50 and 2070-99), relative to the baseline period(1981-2010), are estimated and analyzed. The results show that the future T_x and T_w of entire China will increase by 1.5-5℃ on average around 2085 under different RCPs. Future increases in T_x and T_w exhibit high spatial heterogeneity, ranging from 1.2 to 6℃ across different regions and RCPs. By around 2085, the mean duration of heat waves will increase by 5 days per annum under RCP8.5. According to T_x, heat waves will mostly occur in Northwest and Southeast China, whereas based on T_w estimates, heat waves will mostly occur over Southeast China and the mean heat wave duration will be much longer than those from T_x. The total extreme hot days(T_x or T_w > 35℃) will increase by 10-30 days. Southeast China will experience the severest heat stress in the near future as extreme high temperature and heat waves will occur more often in this region, which is particularly true when heat waves are assessed based on T_w. In comparison to those purely temperature-based indices, the index T_w provides a new perspective for heat stress assessment in China.Xingcai LIU Qiuhong TANG Xuejun ZHANG Siao SUN 2018Journal of Meteorological Research2018,32,3:2
7Role of ammonium sulfate in sulfurization flotation of azurite:Inhibiting the formation of copper sulfide colloid and its mechanism显示文摘In this study,the role of(NH_(4))_(2)SO_(4)during the sulfurization of azurite and its response to flotation were investigated.The flotation results showed that adding(NH_(4))_(2)SO_(4)prior to sulfurization decreased the formation of colloid in flotation pulp,and the floatability of the suppressed azurite caused by excess sodium sulfide was restored.After adding(NH_(4))_(2)SO_(4)prior to sulfurization,the formation of Cu(NH_(3))_(n) ^(2+)intermediate products changed the path of the sulfurization reaction,which slowed the direct impact of HSon the azurite surface.The nucleation rate was reduced,and the growth of copper sulfide crystal was improved.Covellite(syn,CuS)with larger crystal grains was formed on the azurite surface,thereby enhancing the mechanical stability of copper sulfide products onto the mineral surface.Therefore,the generated copper sulfide colloid significantly reduced,ultimately promoting the effective adsorption of xanthate on the azurite surface.Jinpeng Cai Chao Su Yinyu Ma Xingcai Yu Rong Peng Jiangli Li Xiaolin Zhang Jianjun Fang Peilun Shen Dianwen Liu 2022International Journal of Mining Science and Technology2022,32,3:2
8Summary of the AAPG research symposium on lacustrine basin exploration in China and Southeast Asia显示文摘Katz B J Liu Xingcai 1998AAPG Bulletin1998,2,7:1
9Bioresource Upgrade for Sustainable Energy,Environment,and Biomedicine显示文摘We conceptualize bioresource upgrade for sustainable energy,environment,and biomedicine with a focus on circular economy,sustainability,and carbon neutrality using high availability and low utilization biomass(HALUB).We acme energy-efficient technologies for sustainable energy and material recovery and applications.The technologies of thermochemical conversion(TC),biochemical conversion(BC),electrochemical conversion(EC),and photochemical conversion(PTC)are summarized for HALUB.Microalgal biomass could contribute to a biofuel HHV of 35.72 MJ Kg^(-1)and total benefit of 749$/ton biomass via TC.Specific surface area of biochar reached 3000 m^(2)g^(-1)via pyrolytic carbonization of waste bean dregs.Lignocellulosic biomass can be effectively converted into bio-stimulants and biofertilizers via BC with a high conversion efficiency of more than 90%.Besides,lignocellulosic biomass can contribute to a current density of 672 mA m^(-2)via EC.Bioresource can be 100%selectively synthesized via electrocatalysis through EC and PTC.Machine learning,techno-economic analysis,and life cycle analysis are essential to various upgrading approaches of HALUB.Sustainable biomaterials,sustainable living materials and technologies for biomedical and multifunctional applications like nano-catalysis,microfluidic and micro/nanomotors beyond are also highlighted.New techniques and systems for the complete conversion and utilization of HALUB for new energy and materials are further discussed.Fanghua Li Yiwei Li KSNovoselov Feng Liang Jiashen Meng Shih‑Hsin Ho Tong Zhao Hui Zhou Awais Ahmad Yinlong Zhu Liangxing Hu Dongxiao Ji Litao Jia Rui Liu Seeram Ramakrishna Xingcai Zhang 2023Nano-Micro Letters2023,15,3:1
10Evaluation of Global Gridded Precipitation and Temperature Datasets against Gauged Observations over the Upper Tekeze River Basin,Ethiopia显示文摘The availability of satellite and reanalysis climate datasets and their applicability have been greatly promoted in hydro-climatic studies.However,such climatic products are still subject to considerable uncertainties and an evaluation of the products is necessary for applications in specific regions.This study aims to evaluate the reliability of nine gridded precipitation and temperature datasets against ground-based observations in the upper Tekeze River basin(UTB)of Ethiopia from 1982 to 2016.Precipitation,maximum temperature(Tmax),minimum temperature(Tmin),and mean temperature(Tmean)were evaluated at daily and monthly timescales.The results show that the best estimates of precipitation are from the Eart H2 Observe,WFDEI,and ERA-Interim reanalysis data Merged and Bias-corrected for the Inter-Sectoral Impact Model Intercomparison Project(EWEMBI),and the Climate Hazards Group Infra Red Precipitation with Station data(CHIRPS)datasets.The percentage biases and correlation coefficients(CCs)are within±15%and>0.5,respectively,for both EWEMBI and CHIRPS at the two timescales.All products underestimate the drought conditions indicated by the standardized precipitation index(SPI),while the EWEMBI and CHIRPS datasets show higher agreement with the observations than other datasets.The Tmean estimates produced by the ECMWF ReAnalysis version 5(ERA5)and the Climate Hazards Group Infra Red Temperature with Station data(CHIRTS)are the closest to the observations,with CCs of 0.65 and 0.55,respectively,at the daily timescale.The CHIRTS and EWEMBI datasets show better representations of Tmax(T_(min)),with CCs of 0.69(0.72)and 0.62(0.68),respectively,at the monthly timescale.The temperature extremes are better captured by the ERA5(T_(mean)),CHIRTS(T_(max)),and EWEMBI(T_(min))datasets.The findings of this study provide useful information to select the most appropriate dataset for hydrometeorological studies in the UTB and could help to improve the regional representation of global datasets.Kidane Welde REDA Xingcai LIU Qiuhong TANG Tesfay Gebretsadkan GEBREMICAEL 2021Journal of Meteorological Research2021,35,4:1
11The electric field in sandstorm can strongly affect the sand ?s scattering properties显示文摘Li Xingcai Liu Dandan Min Xing 2014Journal of Quantitative Spectroscopy and Radiative Transfer2014,149,:1
12Climate change and water security in the northern slope of the Tianshan Mountains显示文摘Water security is under threat worldwide from climate change. A warming climate would accelerate evaporationand cryosphere melting, leading to reduced water availability and unpredictable water supply. However, thewater crisis in the Northern Slope of Tianshan Mountains(NSTM) faces dual challenges because water demandsforfast-growing urban areas have put heavy pressure on water resources. The mountain-oasis-desert system featuresglacier-fed rivers that sustain intensive water use in the oasis and end in the desert as fragile terminal lakes.The complex balance between water conservation and economic development is subtle. This paper investigateschanges in hydroclimatic variables and water security-related issues on the NSTM. The spatiotemporal variationsin glaciers, climatic variables, rivers, lakes and reservoirs, groundwater, surface water, human water use, andstreamflow were analyzed for the past four decades. The results show that temperature in the NSTM exhibitedan apparent upward trend with a more significant warming rate in the higher altitude regions. Glacier massloss and shrinkage was strong. The average annual streamflow increased from 1980-1989 to 2006–2011 at mosthydrological stations. The monthly dynamics of surface water area showed notable variability at both inter-annual and seasonal scales, revealing the impacts of both natural and anthropogenic drivers on surface wateravailability in the region. The terrestrial water storage anomaly showed a decreasing trend, which might berelated to groundwater pumping for irrigation. Human water use for agriculture and industry grew with theincrease in cultivated land area and gross domestic product (GDP). The increased agricultural water use wasstrongly associated with the expansion of oases. It is unclear whether water availability would remain high underfuture climatic and hydrological uncertainties, posing challenges to water management. In the context of rapidurban growth and climate change, balancing water for humans and nature is vital in achieving the SustainableDevelopment Goals (SDGs) in NSTM. This study provides a baseline understanding of the interplay among water,climate change, and socio-economic development in NSTM. It would also shed light on wise water managementunder environmental changes for other rapidly developing mountain-oasis-desert systems worldwide.Qiuhong Tang Xingcai Liu Yuanyuan Zhou Puyu Wang Zhongqin Li Zhixin Hao Suxia Liu Gang Zhao Bingqi Zhu Xinlin He Fadong Li Guang Yang Li He Haoxin Deng Zongxia Wang Xiang Ao Zhi Wang Paul P.J.Gaffney Lifeng Luo 2022Geography and Sustainability2022,3,3:1
13Immunogenic-cell-killing and immunosuppression-inhibiting nanomedicine显示文摘Combining chemo-therapeutics with immune checkpoint inhibitors facilitates killing cancer cells and activating the immune system through inhibiting immune escape.However,their treatment effects remain limited due to the compromised accumulation of both drugs and inhibitors in certain tumor tissues.Herein,a new poly(acrylamide-co-acrylonitrile-co-vinylimidazole-co-bis(2-methacryloyl)oxyethyl disulfide)(PAAVB)polymer-based intelligent platform with controllable upper critical solution temperature(UCST)was used for the simultaneous delivery of paclitaxel(PTX)and curcumin(CUR).Additionally,a hyaluronic acid(HA)layer was coated on the surface of PAAVB NPs to target the CD44-overexpressed tumor cells.The proposed nanomedicine demonstrated a gratifying accumulation in tumor tissue and uptake by cancer cells.Then,the acidic microenvironment and high level of glutathione(GSH)in cancer cells could spontaneously decrease the UCST of polymer,leading to the disassembly of the NPs and rapid drug release at body temperature without extra-stimuli.Significantly,the released PTX and CUR could induce the immunogenic cell death(ICD)to promote adaptive anti-tumor immunogenicity and inhibit immunosuppression through suppressing the activity of indoleamine 2,3-dioxygenase 1(IDO1)enzyme respectively.Therefore,the synergism of this intelligent nanomedicine can suppress primary breast tumor growth and inhibit their lung metastasis.Ying Wang Di Gao Yan Liu Xiaoqing Guo Shuojia Chen Li Zeng Jinxuan Ma Xingcai Zhang Zhongmin Tian Zhe Yang 2021Bioactive Materials2021,6,6:0
14Scalable fabrication and active site identification of MOF shell-derived nitrogen-doped carbon hollow frameworks for oxygen reduction显示文摘Nitrogen-doped carbon materials as promising oxygen reduction reaction(ORR) electrocatalysts attract great interest in fuel cells and metal-air batteries because of their relatively high activity, high surface area, high conductivity and low cost. To maximize their catalytic efficiency, rational design of efficient electrocatalysts with rich exposed active sites is highly desired. Besides, due to the complexity of nitrogen species, the identification of active nitrogen sites for ORR remains challenging. Herein, we develop a facile and scalable template method to construct high-concentration nitrogen-doped carbon hollow frameworks(NC), and reveal the effect of different nitrogen species on theirORRactivity on basis of experimental analysis and theoretical calculations. The formation mechanism is clearly revealed, including low-pressure vapor superassembly of thin zeolitic imidazolate framework(ZIF-8) shell on ZnO templates,in situ carbonization and template removal. The obtained NC-800 displays better ORR activity compared with other NC-700 and NC-900 samples. Our results indicate that the superior ORR activity of NC-800 is mainly attributed to its content balance of three nitrogen species. The graphitic N and pyrrolic N sites are responsible for lowering the working function, while the pyridinic N and pyrrolic N sites as possible active sites are beneficial for increasing the density of states.Jiashen Meng Ziang Liu Xiong Liu Wei Yang Lianzhou Wang Yan Li Yuan-Cheng Cao Xingcai Zhang Liqiang Mai 2021Journal of Materials Science & Technology2021,,7:0
15Exploration Theory and Method in Jiyang Composite Oil and Gas Area显示文摘ExplorationTheoryandMethodinJiyangCompositeOilandGasAreaLiuXingcai(ChiefGeologist,ShengliPetroleumAdministrativeBureau)YangSh...Liu Xingcai(Chief Geologist,Shengli Petroleum Administrative Bureau)Yang Shenbiao(Chief Geologist,Geological Research Institute of Shengli Petroleum Administrative Bureau) 1995China Oil & Gas1995,2,1:0
16Correlation between sarcopenia and vital capacity in elderly people in Nanning显示文摘To investigate therelationship between sarcopenia and vital capacity(VC)in older adults in Nanning by investigating their humanbody composition and VC.A total of 355 middle-aged and elderly people(male 86,female 269)in Nanning wererandomly selected,their VC and body composition were measured by using the vital capacity tester and bodycomposition analyzer.①VC,BMI,skeletal muscle mass index(SMI)of male were higher than those of female,but the fat mass(FM)and body fat rate(BF%)were lower than that of female.②The VC in the male sarcopeniagroup was lower than that of the control group.③BMI and systemic muscle mass(SMM)in the male and femalesarcopenia group were lower than those in the control group,and the FM and trunk muscle mass(TMM)in thefemale group were lower than those in the control group.Wu Siyi Cheng Chunfeng Liu Qi Jiang Jiayang He Kuntu Chen Xingcai Xu Lin Deng Qiongying 2021解剖学杂志2021,44,S01:0
17Spatio-Temporal Characteristics of Standardized Precipitation Index in the Taihu Basin during 1951-2000显示文摘Spatial and temporal characteristics of standardized precipitation index (SPI), which is widely used for drought/flood monitoring, are investigated in this study. The purpose is to obtain a reasonable primary scheme of zoning on the basis of drought/ wetness conditions in the study area. Spatio-temporal distributions of SPI with the time scales of 3 months and 12 months are investigated with the datasets of precipitation in the Taihu basin during past decades (1951-2000). Results indicate that SPI series of 3 months show random fluctuation while that of 12 months behaves like 1/f noise. SPI series of 3 months show little trend while that of 12 months show significant trend at several stations. Drought magnitude (DM) is also estimated on the basis of SPI values to assess drought condition. No trend is detected in DMs with time scales of both 3 months and 12 months. Spatial variability of DM is analyzed by mapping the DM with 12 months for extreme drought and wetness, and regional characteristics are analyzed for DM.LIU Xingcai XU Zongxue LIU Bo 2009Wuhan University Journal of Natural Sciences2009,14,6:0
18INFLUENCE OF LITHOGRAPHICAL PROCESSES ON THE SUPERCONDUCTIVITY OF YBaCuO THIN FILMS显示文摘This letter presents the results of the influnces of an ultra-violet lithography(UVL)and a h e r beam canning lithography(LBSL)on the superconductivity of YBaCuO thin films on SrTiO3 substrates.The degeneration of superconductivity of YBaCuO thin films in UVL process is more than that in LBSL process.SUN Yuping LIU Genqing XU Xingcai ZHU Xi LUO Tangsheng 1990Chinese Physics Letters1990,7,1:0
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