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| 1 | Gut microbial balance and liver transplantation: alteration, management, and prediction显示文摘肝移植是为终端阶段肝疾病的常规治疗。然而,几复杂并发症仍然妨碍幸存率。肠的障碍破坏广泛地在收到肝的病人之中被观察移植并且因为在肠和肝之间的关系,受不了 ischemiareperfusion 或拒绝损害,两个在解剖和功能。重要地,内脏 microbiota 的产生改变在这个过程期间加重接枝机能障碍。这篇文章为内脏考察研究进步微生物引起的改变和肝移植。特别,这个工作也在内脏的管理上评估研究微生物引起的改变和在肝移植期间利用微生物引起的改变的可能的损害的预言。另外,我们为关于的研究建议可能的方向在肝移植期间毁坏微生物引起的改变并且在肝移植在微生物引起的改变的利用上提供一个假设。目的是不仅预言 perioperative 损害而且作为治疗的一个方法工作或甚至禁止肝移植的拒绝。 | Xinyao Tian Zhe Yang Fangzhou Luo Shusen Zheng | 2018 | Frontiers of Medicine2018，12，2： | 5 |
| 2 | Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic liver transplantation显示文摘Understanding the effect of immunosuppressive agents on intestinal microbiota is important to reduce the mortality and morbidity from orthotopic liver transplantation (OLT). We investigated the relationship between the commonly used immunosuppressive agent cyclosporine A (CSA) and the intestinal microbial variation in an OLT model. The rat samples were divided as follows:(1) N group (normal control);(2) I group (isograft LT, Brown Norway [BN] rat to BN);(3) R group (allograft LT, Lewis to BN rat);and (4) CSA group (R group treated with CSA). The intestinal microbiota was assayed by denaturing gradient gel electrophoresis profiles and by using real-time polymerase chain reaction. The liver histopathology and the alanine/aspartate aminotransferase ratio after LT were both ameliorated by CSA. In the CSA group, the numbers of rDNA gene copies of Clostridium cluster I, Clostridium cluster XIV, and Enterobacteriaceae decreased, whereas those of Faecalibacterium prausnitzii increased compared with the R group. Cluster analysis indicated that the samples from the N, I, and CSA groups were clustered, whereas the other clusters contained the samples from the R group. Hence, CSA ameliorates hepatic graft injury and partially restores gut microbiota following LT, and these may benefit hepatic graft rejection. | Junjun Jia Xinyao Tian Jianwen Jiang Zhigang Ren Haifeng Lu Ning He Haiyang Xie Lin Zhou Shusen Zheng | 2019 | Frontiers of Medicine2019，13，4： | 5 |
| 3 | New approaches for rare earth-magnesium based hydrogen storage alloys显示文摘As the most possibility applied to the next generation negative electrode materials of Ni/ MH second battery,rare earth(RE)-magnesium(Mg) based alloys have been developed over the last few years. Recent advances about the RE-Mg based intermetallic compounds on the crystal structures, hydrogenation behaviors and electrochemical performances are reviewed in the paper. On the other hand, new results about the preparation and modification methods of the alloys are also covered in details. | Huaiwei Zhang Xinyao Zheng Xiao Tian Yang Liu Xingguo Li | 2017 | Progress in Natural Science:Materials International2017，27，1： | 2 |
| 4 | Meta-optics inspired surface plasmon devices显示文摘Surface plasmons(SPs)are electromagnetic surface waves that propagate at the interface between a conductor and a dielectric.Due to their unique ability to concentrate light on two-dimensional platforms and produce very high local-field intensity,SPs have rapidly fueled a variety of fundamental advances and practical applications.In parallel,the development of metamaterials and metasurfaces has rapidly revolutionized the design concepts of traditional optical devices,fostering the exciting field of meta-optics.This review focuses on recent progress of meta-optics inspired SP devices,which are implemented by the careful design of subwavelength structures and the arrangement of their spatial distributions.Devices of general interest,including coupling devices,on-chip tailoring devices,and decoupling devices,as well as nascent SP applications empowered by sophisticated usage of meta-optics,are introduced and discussed. | Quan Xu Yuanhao Lang Xiaohan Jiang Xinyao Yuan Yuehong Xu Jianqiang Gu Zhen Tian Chunmei Ouyang Xueqian Zhang Jiaguang Han Weili Zhang | 2023 | Photonics Insights2023，2，1： | 1 |
| 5 | Lonicera caerulea polyphenols inhibit fat absorption by regulating Nrf2-ARE pathway mediated epithelial barrier dysfunction and special microbiota显示文摘Scope:High-fat diet(HFD)induces imbalance in the small intestine environment,where fat digestion and absorption mainly take place.This study aimed to elucidate the mechanisms by which Lonicera caerulea polyphenols(LCP)might inhibit fat absorption,from the perspective of small intestine microbiota and epithelial barrier integrity.Methods and results:Male Sprague-Dawley rats were given HFD with or without co-administration of LCP for 8 weeks.The results showed that LCP supplementation significantly decreased the levels of serum triglycerides(TG),total cholesterol(TC),and low-density lipoprotein cholesterol(LDL-C),and increased the contents of fecal sterols,in HFD rats.LCP also inhibited the dysfunction of the small intestine epithelial barrier,via alleviating the oxidative stress activated by Nrf2-ARE pathway,and by modulating the expressions of pro-inflammatory factors such as tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),cyclooxygenase-2(COX-2),nuclear factor kappa-B p65(NF-κB p65)and inducible nitric oxide synthase(iNOS)in the small intestine.Additionally,LCP administration restored the balance in small intestine microbiota and increased the abundance of the specific bacteria,such as Lactobacillus,involved in fat absorption.Conclusion:Our results demonstrated that LCP may be beneficial to inhibit fat absorption.The mechanism seems to be associated with the protection of the epithelial barrier integrity and the modulation of specific bacteria in the small intestine. | Yuehua Wang Ningxuan Gao Andrea Nieto-Veloza Lingxi Zhou Xiyun Sun Xu Si Jinlong Tian Yang Lin Xinyao Jiao Bin Li | 2023 | Food Science and Human Wellness2023，12，4： | 1 |
| 6 | Design of mesoporous ZnCoSiOx hollow nanoreactors with specific spatial distribution of metal species for selective CO_(2)hydrogenation显示文摘In heterogeneous catalysis,the precise placement of active components to perform unique functions in cooperation with each other is a tremendous challenge.The migration of matter on micro/nano-scale caused by diffusion is a promising pathway for design of catalytic nanoreactors with precise active sites location and controllable microenvironment through compartmentalization and confinement effects.Herein,we report two categories of mesoporous ZnCoSiOx hollow nanoreactors with different metal distributions and microenvironment engineered by the diffusion behavior of metal species in confined nanospace.Double-shelled hollow structures with well-distributed metal species were obtained by adopting core@shell structured ZnCo-zeolitic imidazolate framework(ZIF)@SiO2 as a template and employing three stages of hydrothermal treatment including the decomposition of ZIF,diffusion of metal species into the silica shell,and Ostwald ripening.Additionally,the formation of yolk@shell structure with a collective(Zn-Co)metal oxide as the yolk was achieved by direct pyrolysis of ZnCo-ZIF@SiO2.In CO_(2)hydrogenation,ZnCoSiOx with double-shelled hollow structures and yolk@shell structures respectively afford CO and CH_(4)as main product,which is related with different dispersion and location of active sites in the two catalysts.This study provides an efficient method for the synthesis of catalytic nanoreactors on the basis of insights of the atomic diffusion in confined space at the mesoscale. | Xinyao Wang Runping Ye Melis S.Duyar Cameron Alexander Hurd Price Hao Tian Yanping Chen Na Ta Hao Liu Jian Liu | 2023 | Nano Research2023，16，4： | 0 |
| 7 | Construction of hollow mesoporous silica nanoreactors for enhanced photo-oxidations over Au-Pt catalysts显示文摘It is highly desirable to design hollow structures with multi-scale functions by mimicking cells for the construction of micro/nanoreactors.Herein,we report the construction of hollow-structured submicrometer-photoreactors with bimetallic catalysts loaded within mesoporous silicas.The synthesis parameters are optimized to study the evolution of hollow structure through hydrothermal treatment and an‘adhesive-contraction’formation mechanism is proposed.AuPt@HMZS catalysts exhibited a broader absorbance region under visible light and the adsorption edge displayed a red-shift,indicating the strong metal-metal interactions at the alloy interface.The reaction performance of the coupled Au-Pt catalysts can be tuned to achieve excellent catalytic activity in cinnamyl alcohol oxidation to cinnamic acid for 3.1 mmol g^-1 with 99%selectivity.The proposed strategy to build hollow structures as multifunctional micro/nanoreactors is promising for the design of high-performance and sustainable catalysts for chemical synthesis. | Hao Tian Jinhui Zhao Xinyao Wang Lizhuo Wang Hao Liu Guoxiu Wang Jun Huang Jian Liu G.Q.(Max)Lu | 2020 | National Science Review2020，7，11： | 0 |
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