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| 1 | Oligolayered Ti3C2Tx MXene towards high performance lithium/sodium storage显示文摘Nano Research volume 13,pages1659–1667(2020)Cite this article 232 Accesses 3 Citations Metrics details Abstract 2D MXenes are highly attractive for achieving ultrafast and stable lithium/sodium storage due to their good electric conductivity and abundant redox active sites.While,effective strategies for scalable preparation of oligolayered MXenes are still under exploration.Herein,oligolayered Ti3C2Tx MXene is successfully obtained after conventional synthesis of multilayered Ti3C2 and subsequent delamination process via an organic solvent of tetramethyl-ammonium hydroxide(TMAOH).Comprehensive electrochemical study reveals that surface-controlled redox reaction dominated the charge storage behavior of oligolayered Ti3C2Tx with fast reaction kinetics.Impressively,the obtained oligolayered Ti3C2Tx exhibits excellent lithium/sodium storage performance,featured for a high specific capacity of 330 mAhg^−1 at 1.0 Ag^−1 after 800 cycles for lithium storage and 280 mAhg^−1 at 0.5 Ag^−1 after 500 cycles for sodium storage.Such impressive performance will advance the development of oligolayered Ti3C2Tx based materials for lithium/sodium storage and even broaden their application into energy storage. | Xiaolan Song Hui Wang Shengming Jin Miao Lv Ying Zhang Xiaodong Kong Hongmei Xu Ting Ma Xinyuan Luo Hengfeng Tan Dong Hu Chaoyong Deng Xinghua Chang Jianlong Xu | 2020 | Nano Research2020，13，6： | 4 |
| 2 | OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice显示文摘Grain chalkiness,an undesirable trait caused by complex factors,has great negative impacts on the quality and economic value of rice.However,little is known about the regulatory mechanism of grain chalkiness,particularly the effect of endoplasmic reticulum(ER)stress.Here,a genome-wide association study(GWAS)reveals that the transcription factor Osb ZIP60 is a vital regulator of rice grain chalkiness.Genetic analysis demonstrates that knockout of Osb ZIP60 results in extremely high grain chalkiness and aberrant structure of storage substances.Notably,the expression of unfolded protein response(UPR)genes,such as OsbZIP50,Os Bi P1,Os Bi P2 and Os Bi P3,is up-regulated in the endosperm cells of osbzip60,and overexpression of all these UPR genes causes various degrees of chalkiness.Furthermore,Osb ZIP60 is found to activate the expression of key genes related to grain chalkiness,such as GPA3,FSE1,FLO7,Chalk5,Os NF-YB1,and Os PK2,whose expression is significantly suppressed in osbzip60 and overexpression lines of Osb ZIP50,Os Bi P1,Os Bi P2,and Os Bi P3.Our study provides novel insights into the function of Osb ZIP60 and the role of the UPR pathway in the formation of grain chalkiness in rice. | Weiping Yang Pengkun Xu Juncheng Zhang Shuo Zhang Zhenwei Li Ke Yang Xinyuan Chang Yibo Li | 2022 | Journal of Genetics and Genomics2022，49，5： | 4 |
| 3 | Effect of Transgenic Corn Cultivation and Sampling Location on Feeding Habits of Collembola显示文摘 | Baifeng Wang Liang Chang Donghui Wu Xinyuan Song | 2014 | Journal of Agricultural Science and Technology(A)2014，4，3： | 1 |
| 4 | Nerve regeneration following implantation of axotomized nerves pretreated with gamma radiation显示文摘BACKGROUND: It has been shown that irradiation to the neurolemma can reduce immunogenicity. However, it is still poorly understood whether the degenerated nerve can affect peripheral nerve regeneration. OBJECTIVE: To observe the effect of radiation-damaged nerve transplantation on functional recovery of the peripheral nerve. DESIGN, TIME AND SETTING: Self-control animal trial was performed at the Experimental Center of Orthopedics, Tangdu Hospital of Fourth Military Medical University from January to October 2005. MATERIALS: Fifty-four healthy, Chinese rabbits, irrespective of gender, were randomly divided into experimental (n = 36) and control (n = 18) groups. A 60 Co γ-radiation machine and NDI-200 nerve electro-myograph were provided by the Experimental Center of Orthopedics, Tangdu Hospital of Fourth Military Medical University. METHODS: A median incision was made in the posterior right thigh of rabbits after abdominal anesthesia. A 30-mm segment of sciatic nerve was excised from the inferior margin of the piriform muscle to the tibiofibular intersection. The sciatic nerve in the experimental group was sterilely radiated with 350 Gy for 9.5 minutes. The damaged nerve segment was then re-transplanted. In the control group, the sciatic nerve was re-transplanted directly following excision. Nerve conduction velocity was determined at 4, 6, and 8 months post-surgery. MAIN OUTCOME MEASURES: Functional assessments, such as gait, nutritional status of skin on dorsum of foot, toe spreading reflex, and foot holding, were made between 1 and 180 days post-surgery. The common peroneal nerve and tibial nerve reflexes under clamping were observed at 4, 6, and 8 months post-surgery to evaluate functional restoration of the peripheral nerve. Electromyogram was performed to observe nerve conduction velocity. RESULTS: From postoperative days 1 to 26, the limbs that were transplanted with irradiated nerve exhib- ited dragged walking, foot drop, sole ulcers, depilation, self-induced injury to the toes, and other denervation behaviors. From 95 to 120 days after re-transplantation, the ulcers recovered, in addition to recovered toe-spreading reflex. When subjected to the clamping text, nerve reflex occurred. Compared with animals transplanted with normal nerve, nerve conduction velocity in the experimental group was slower at 4 and 6 months post-surgery (P < 0.05 and P < 0.01). At 8 months after surgery, nerve conduction velocity recovered in the experimental group, but was still slower than the control group (P < 0.05). Recovered conduction velocity in the experimental group was significantly faster than the control group (P < 0.05). CONCLUSION: Reinnervation was achieved by pre-treating a 30-mm segment of sciatic nerve with 350-Gy radiation. Although radiation improved nerve conduction velocity recovery following re-transplantation, the velocity was not completely recovered to normal levels. | Xinyuan Wang Dehai Chang Shihua Xie Chunming Han Jinsheng Sheng | 2008 | Neural Regeneration Research2008，3，10： | 1 |
| 5 | Dissipative Particle Dynamics Study on Platycodin's Solubilization Enhancing Effect Towards Five Drug Components显示文摘In this study,a dissipative particle dynamics mehtod was used to study the solubilization enhancing effect of platycodin towards 5 different drug components.Two factors were mainly considered,including the ,XlogP value of drug components and the sugar chain length of platycodin.As a result,it was found that there was an optimal drug XlogP value for the solubilization enhancing effect of platycodin,and it was different between the drug's own XlogP value and the optimal drug XlogP value of platycodin that determines the solubilization enhancing effect. | WU Zhimin DING Haiou YANG Chang GUO Shujuan DAI Xingxing SHI Xinyuan | 2019 | Chemical Research in Chinese Universities2019，35，1： | 0 |
| 6 | PanGu Drug Model: learn a molecule like a human显示文摘Dear Editor,Recent achievements in large-scale pre-trained models like GPT-3 and PanGu-α have demonstrated astounding performances in many downstream tasks of natural language processing (NLP),confirming AI to be user-oriented for even industrial applications.Deep learning has been recognized as the most promising technology for pharmaceuticals,a powerful molecule pre-trained model that could economize researchers’tons of time.For the strategic application of AI capabilities to the drug discovery field,we pre-trained a model called PanGu Drug Model with 1.7 billion small molecules from ZINC20 (Irwin et al.,2020),DrugSpaceX(Yang et al.,2021),and UniChem (Chambers et al.,2013). | Xinyuan Lin Chi Xu Zhaoping Xiong Xinfeng Zhang Ningxi Ni Bolin Ni Jianlong Chang Ruiqing Pan Zidong Wang Fan Yu Qi Tian Hualiang Jiang Mingyue Zheng Nan Qiao | 2023 | Science China(Life Sciences)2023，66，4： | 0 |
| 7 | Nanomembrane folding origami:Geometry control and micro-machine applications显示文摘Three-dimensional(3D)microstructures have important applications in a wide range of engineering fields.A strategy of nanomembrane folding origami with microdroplet-guided intercalation and strain engineering to construct complex 3D microstructures for micro-machine applications is proposed in the present investigation.The results showed that nanomembranes were released by the microdroplet intercalation and subsequently fold up as creases,or remain flat as facets,depending on the strain design configurations.The 3D geometry can be controlled by the crease design and by an externally applied magnetic field.Moreover,this folding strategy is used to construct magnetic micro-mirror arrays,magnetic micro-robots,and a twin-jet motor platform,showing potential micro-machine applications in optical micro-devices and robotics.This strategy offers a simple,precise,and designable method of folding 3D microstructures for fundamental research and practical applications. | Yang Zong Xinyuan Zhang Yue Wu Yang Wang Chang Liu Borui Xu Gaoshan Huang Jizhai Cui Yongfeng Mei | 2021 | Progress in Natural Science:Materials International2021，31，6： | 0 |
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