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| 1 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017，10，7： | 19 |
| 2 | A Chromosome-Scale Genome Assembly of Paper Mulberry(Bmussonetia papyrifera)Provides New Insights into Its Forage and Papermaking Usage显示文摘Paper mulberry(Broussonetia papyrifera)is a well-known woody tree historically used for Cai Lun papermaking,one of the four great inventions of ancient China.More recently,Paper mulberry has also been used as forage to address the shortage of feedstuff because of its digestible crude fiber and high protein contents.In this study,we obtained a chromosome-scale genome assembly for Paper mulberry using integrated approaches,including Illumina and PacBio sequencing platform as well as Hi-C,optical,and genetic maps.The assembled Paper mulberry genome consists of 386.83 Mb,which is close to the estimated size,and 99.25%(383.93 Mb)of the assembly was assigned to 13 pseudochromosomes.Comparative genomic analysis revealed the expansion and contraction in the flavonoid and lignin biosynthetic gene families,respectively,accounting for the enhanced flavonoid and decreased lignin biosynthesis in Paper mulberry.Moreover,the increased ratio of syringyl-lignin to guaiacyl-lignin in Paper mulberry underscores its suitability for use in medicine,forage,papermaking,and barkcloth making.We also identified the rootassociated microbiota of Paper mulberry and found that Pseudomonas and Rhizobia were enriched in its roots and may provide the source of nitrogen for its stems and leaves via symbiotic nitrogen fixation.Collectively,these results suggest that Paper mulberry might have undergone adaptive evolution and recruited nitrogen-fixing microbes to promote growth by enhancing flavonoid production and altering lignin monomer composition.Our study provides significant insights into genetic basis of the usefulness of Paper mulberry in papermaking and barkcloth making,and as forage.These insights will facilitate further domestication and selection as well as industrial utilization of Paper mulberry worldwide. | Xianjun Peng Hui Liu Peilin Chen Feng Tang Yanmin Hu Fenfen Wang Zhi Pi Meiling Zhao Naizhi Chen Hui Chen Xiaokang Zhang Xueqing Yan Min Liu Xiaojun Fu Guofeng Zhao Pu Yao Lili Wang He Dai Xuming Li Wei Xiong Wencai Xu Hongkun Zheng Haiyan Yu Shihua Shen | 2019 | Molecular Plant2019，12，5： | 18 |
| 3 | Emerging in-plane anisotropic two-dimensional materials显示文摘Black phosphorus(BP)is a rapidly up and coming star in two-dimensional(2D)materials.The unique characteristic of BP is its in-plane anisotropy.This characteristic of BP ignites a new type of 2D materials that have low-symmetry structures and in-plane anisotropic properties.On this basis,they offer richer and more unique low-dimensional physics compared to isotropic 2D materials,thus providing a fertile ground for novel applications including electronics,optoelectronics,molecular detection,thermoelectric,piezoelectric,and ferroelectric with respect to in-plane anisotropy.This article reviews the recent advance in characterization and applications of in-plane anisotropic 2D materials. | Liang Li Wei Han Lejing Pi Ping Niu Junbo Han Chengliang Wang Bin Su Huiqiao Li Jie Xiong Yoshio Bando Tianyou Zhai | 2019 | InfoMat2019，1，1： | 16 |
| 4 | Industrial Poverty Alleviation Model in Southwestern High-altitude Mountainous Areas of China——A Case Study of Industrial Poverty Alleviation of Xueshan Township in Luquan County of Yunnan Province through Planting Codonopsis pilosula显示文摘Due to the severe restrictions of natural conditions and ecological environment,high-altitude mountainous areas usually become the ' hard bones' in the battle against poverty. Xueshan Township,Luquan Yi and Miao Autonomous County of Yunnan Province,located in the alpine valley of Jinsha River,is a major township with wide and deep poverty,and the incidence of poverty is up to 45. 00%. In recent years,Xueshan Township has insisted on the battle against poverty,made effort to develop the Codonopsis pilosula industry,and successfully developed a road to poverty alleviation through C. pilosula industry,and formed a unique industrial poverty alleviation model by the end of 2018,the incidence of poverty dropped to 0. 74%. Based on field survey and interview,this paper analyzes and summarizes the specific practices,main results,practical experience and promotion and application measures of the poverty alleviation model of C. pilosula planting industry in Xueshan Township,in the hope of providing certain reference for the targeted poverty alleviation in similar areas in Yunnan Province and other provinces of China. | Zisheng YANG Renyi YANG Yanbo HE Chonghui LU En ZHU Yaohan PI Mingxin WU Ying XIONG | 2019 | Asian Agricultural Research2019，11，3： | 4 |
| 5 | Near-atomic structure of the inner ring of the Saccharomyces cerevisiae nuclear pore complex显示文摘Nuclear pore complexes(NPCs)mediate bidirectional nucleocytoplasmic transport of substances in eukaryotic cells.However,the accurate molecular arrangement of NPCs remains enigmatic owing to their huge size and highly dynamic nature.Here we determined the structure of the asymmetric unit of the inner ring(IR monomer)at 3.73Åresolution by single-particle cryo-electron microscopy,and created an atomic model of the intact IR consisting of 192 molecules of 8 nucleoporins.In each IR monomer,the Z-shaped Nup188–Nup192 complex in the middle layer is sandwiched by two approximately parallel rhomboidal structures in the inner and outer layers,while Nup188,Nup192 and Nic96 link all subunits to constitute a relatively stable IR monomer.In contrast,the intact IR is assembled by loose and instable interactions between IR monomers.These structures,together with previously reported structural information of IR,reveal two distinct interaction modes between IR monomers and extensive flexible connections in IR assembly,providing a structural basis for the stability and malleability of IR. | Zongqiang Li Shuaijiabin Chen Liang Zhao Guoqiang Huang Xiong Pi Shan Sun Peiyi Wang Sen-Fang Sui | 2022 | Cell Research2022，32，5： | 2 |
| 6 | Adsorption behavior of Hg 2+ in aqueous solutions on a novel chelating cross-linked chitosan microsphere显示文摘 | Chunhua Xiong Leilei Pi Xinyi Chen Liqun Yang Chunan Ma Xuming Zheng | 2013 | Carbohydrate Polymers2013，，： | 2 |
| 7 | Synthesis and char- aeterization of ultrafine WC - Co by freeze - drying and spark plasma sintering 显示文摘 | Xiaoli Xi Xiong Pi Zuoren Nie | 2009 | International Journal of Refrac- tory Metals and Hard Materials2009，27，1： | 1 |
| 8 | The kinetic studies of elimination of HCl during thermal decomposition of PVC in the presence of transition metal oxides显示文摘 | Pi H Xiong Y Guo SY | 2005 | Polymer-plastics Technology and Engineering2005，44，2： | 1 |
| 9 | Depression and Cognitive Impairment in Peritoneal Dialysis : A Multicenter Cross-sectional Study 显示文摘 | Dang J Pi HC Xiong zY | 2016 | Am J Kidney Dis2016，67，1： | 1 |
| 10 | Adsorption behavior of Hg2+in aqueous solutions on a novel chelating cross-linked chitosan microsphere显示文摘 | XIONG C H PI L L CHEN X Y | 2013 | Carbohydrate Polymers2013，98，1： | 1 |
| 11 | Hyponatremia and Cognitive Impairment in Patients Treated with Peritoneal Dialysis 显示文摘 | Xu R Pi HC Xiong ZY | 2015 | Clin J Am Soc Nephrol2015，10，10： | 1 |
| 12 | The kinetic studies of elimination of HCl during thermal decomposition of PVC in the presence of transition metal oxides显示文摘 | Pi H Xiong Y Guo SY | 2005 | Polymer-plastics Technology and Engineering2005，44，2： | 1 |
| 13 | Carrageenan oligosaccharides and associated carrageenan-degrading bacteria induce intestinal inflammation in germ-free mice显示文摘Carrageenans(CGNs)are widely used in foods and pharmaceuticals although their safety remains controversial.To investigate the effects of CGNs and CGN-degrading bacteria in the human colon,we screened for CGN degradation by human fecal microbiota,and for inflammatory response to CGNs and/or CGN-degrading bacteria in germ free mice.Thin-layer chromatography indicated that high molecular weight(MW)CGNs(!100 kDa)remained undegraded in the presence of human fecal microbiota,whereas low MW CGNs,i.e.,k-carrageenan oligosaccharides(KCO,~4.5 kDa)were degraded when exposed to seven of eight human fecal samples,although sulfate groups were not removed during degradation.Bacteroides xylanisolvens and Escherichia coli isolates from fecal samples apparently degraded KCO synergistically,with B.xylanisolvens serving as the primary degrader.Combined treatment of KCO with KCO-degrading bacteria led to greater pro-inflammatory effects in the colon and rectum of germ-free mice than either KCO or bacteria alone.Similarly,p-p38-,CD3-,and CD79a-positive immune cells were more abundant in combined treatment group mice than in either single treatment group.Our study shows that KCO-degrading bacteria and the low MW products of KCO can promote proinflammatory effects in mice,and represent two key markers for evaluating CGN safety in foods or medicines. | Yeshi Yin Miaomiao Li Weizhong Gu Benhua Zeng Wei Liu Liying Zhu Xionge Pi Donald A.Primerano Hongwei D.Yu Hong Wei Guangli Yu Xin Wang | 2021 | Journal of Genetics and Genomics2021，48，9： | 1 |
| 14 | The research of red blood cell of the Waxiang in Hunan显示文摘 | Pi JH Zhou JB Xiong HX | 2010 | J HuaihuaUniv2010，29，： | 1 |
| 15 | Adsorption Behavior of Hg 2+ in Aqueous Solutions on a Novel Chelating Cross-Linked Chitosan Microsphere显示文摘 | Xiong Chunhua Pi Leilei Chen Xinyi | 2013 | Carbohydr Polym2013，98，1： | 1 |
| 16 | The kinetic studies of elimination of HC1 during thermal decomposition of PVC in the presence of transition metal oxides 显示文摘 | PI H XIONG Y GUO S Y | 2005 | Polymer-Plastics Technology and Engineering2005，44，2： | 1 |
| 17 | Suppression of angiotensin Ⅱ stimulated responses in aortic vascular smooth muscle cells of experimental cirrhotic rats显示文摘Functional responses to angiotensin Ⅱ (AT-Ⅱ) were determined in aortic vascular smooth muscle cells (VSMCs) from experimental cirrhotic rats. Our data showed that AT-Ⅱ-stimulated extracellular acidification rate (ECAR), which was measured by Cytosensor microphysiometry, was significantly reduced in the aortic VSMCs from the cirrhotic rats as compared to those from the control animals. The ability of AT-Ⅱ to promote formation of inositol phosphates, the second messenger produced by the activation of Gq-coupled receptors, was also considerably suppressed in the cirrhotic VSMCs. Furthermore, the maximal p42/44 MAPK phosphorylation stimulated by AT-Ⅱ was significantly reduced in the cirrhotic VSMCs in contrast to that in the normal VSMCs. Taken together, our data clearly demonstrated that the functional responses to AT-Ⅱ was severely suppressed in aortic VSMCs in cirrhosis, indicating the impairment of general Gq-coupled receptor signaling and subsequent biological function in the cirrhotic VSMCs. | ZHANG RU GUO LIANG WANG PI LI ZHANG YING XIONG WEN BO ZHANG XING PENG WANG DE LING YIN QING JING (Shanghai Institute of Cell Biology, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China )(Department of Gastroenterology, Shanghai F | 1999 | Cell Research1999，9，2： | 0 |
| 18 | Femtosecond Spectroscopy Studies on YBa_(2)Cu_(3)O_(7-x) and PrBa_(2)Cu_(3)O_(7-x) a Epitaxial Thin Films显示文摘We report the results of femtosecond spectroscopy studies on YBa_(2)Cu_(3)O_(7-x )and PrBa_(2)Cu_(3)O_(7-x )(x=0.1)epitaxial thin films at room temperature.The transient reSectivity signals ΔR(t)in the samples are consistent with a band filliitg model.The relaxation times of ΔR(t)in YBa_(2)Cu_(3)O_(7-x ) increase from less th&n 100 fs to more than Ips with increasing x and with substitution of Pr for Y.These results reveal that in high Tc superconductors decrease of carrier concentration slows down the carrier-phonon coupling. | ZENG Wensheng LIN Weizhu ZHU Derui PI Feipeng XU Geng MO Dang XIA Zongju ZOU Yinghua WANG Jingjing YUAN Ping XIONG Guangcheng GAN Zizhao | 1993 | Chinese Physics Letters1993，10，12： | 0 |
| 19 | Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days显示文摘Reportedly,proteins involved in lipid metabolism change significantly in the jejunal crypt cells of earlyweaned piglets,but the exact lipid profile change remains uncertain.In the present study,32 piglets weaned at 21 d of age were randomly divided into 4 groups with 8 replicates.The jejunal crypt cells of a group of piglets on the post-weaning day(PWD)1,3,7,and 14 were isolated per time point.Crypt cell lipid profiles were analyzed using ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry.This study showed that piglets suffered the greatest weaning stress on PWD 3 in terms of the lowest relative weight of the small intestine,the highest relative weight of the spleen,and the highest levels of malondialdehyde,cholesterol,and low-density lipoprotein cholesterol.The lipid profile of jejunal crypt cells including carnitine,sulfatide,sphingomyelin,hexosylceramide,and ceramide greatly changed after weaning,especially between PWD3 and 14(P<0.05).The differential lipid species between these 2 d were mainly involved in the glycerophospholipid metabolism pathway.In addition,potential lipid biomarkers for weaning stress in crypt cells such as phosphatidylcholine(PC)(9:0/26:1),PC(17:0/18:2),carnitine(24:0),carnitine(22:0),sphingomyelin(d14:1/22:0),PC(P-18:0/18:4),phosphatidylethanolamine(P-16:0/20:4),phosphatidylinositol(15:1/24:4),and dihexosylceramide(d14:1/26:1)were identified.The changes in lipid profile might be related to the inflammation caused by early weaning.These findings might provide new therapeutical targets for intestinal dysfunctions caused by weaning stress. | Yirui Shao Xia Xiong Kexing Wang Pi Cheng Lijun Zou Jian Zhou Ming Qi Yulong Yin | 2022 | Animal Nutrition2022，，4： | 0 |
| 20 | Field-induced anisotropic magnetic phase transitions and tricritical phenomena in GdCr_(6)Ge_(6)显示文摘The interaction between complex magnetic structures and non-trivial band structures in ternary rare-earth GdCr_(6)Ge_(6) induces exotic and abundant electro-magnetic phenomena.In this work,we perform a systematical investigation on critical behaviors and magnetic properties of the single-crystal GdCr_(6)Ge_(6).The temperature,field,and angle dependence of magnetization unveils strong magnetic anisotropy along the c-axis and isotropic characteristic in the ab-plane.Critical exponentsβ=0.252(1),γ=0.905(9),δ=4.606(3)for H//ab,andβ=0.281(3),γ=0.991(8),δ=4.541(5)for H//c are obtained by the modified Arrott plot method(MAP)and critical isotherm(CI)analysis.The determined exponents for both directions are consistent with the theoretical prediction of a tricritical mean-field model.Based on detailed magnetization measurements and universality scaling,comprehensive magnetic phase diagrams of GdCr6Ge6for H//ab and H//c are constructed,which reveal that the external field induces a ferromagnetic(FM)transition for H//ab while a ferrimagnetic(FIM)one for H//c.Two tricritical points are determined for H//ab(11.2 K,266.3 Oe)and H//c(11.3 K,3.3 kOe)on the phase diagrams,respectively.The field-induced anisotropic magnetic configurations and multiple phases are clarified,where the moments of Gd and Cr form FM coupling for H//ab while FIM one for H//c via the interaction between Gd and Cr sublattices. | Zan Du Azizur Rahman Jiangpeng Song Jun Zhao Wei Liu Jiyu Fan Chunlan Ma Min Ge Yimin Xiong Li Pi Lei Zhang Yuheng Zhang | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，9： | 0 |
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