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| 1 | Effect of inorganic carbon on anaerobic ammonium oxidation enriched in sequencing batch reactor显示文摘The present lab-scale research reveals the enrichment of anaerobic ammonium oxidation microorganism from methanogenic anaerobic granular sludge and the effect of inorganic carbon(sodium bicarbonate)on anaerobic ammonium oxidation.The enrichment of anammox bacteria was carried out in a 7.0-L sequencing batch reactor(SBR)and the effect of bicarbonate on anammox was conducted in a 3.0-L SBR.Research results,especially the biomass,showed first signs of anammox activity after 54 d cultivation with synthetic w... | LIAO, Dexiang LI, Xiaoming YANG, Qi ZENG, Guangming GUO, Liang YUE, Xiu | 2008 | Journal of Environmental Sciences2008，20，8： | 28 |
| 2 | Study of heteroserum-induced rat liver fibrosis model and its mechanism显示文摘StudyofheteroseruminducedratliverfibrosismodelanditsmechanismHUANGZhiGang,ZHAIWeiRong,ZHANGYueEandZHANGXiuRongSubjecthea... | HUANG Zhi Gang, ZHAI Wei Rong, ZHANG Yue E and ZHANG Xiu Rong | 1998 | World Journal of Gastroenterology1998，4，3： | 22 |
| 3 | Traditional Chinese medicine integrated with chemotherapy for stage Ⅳ non-surgical gastric cancer: a retrospective clinical analysis显示文摘OBJECTIVE: Traditional Chinese medicine(TCM) is regarded as an important treatment for gastric cancer patients, especially for those in advanced stage. To evaluate the effects of TCM treatment on gastric cancer patients, the authors performed a retrospective study to report the result of the integrated treatment of TCM with chemotherapy for stage IV non-surgical gastric cancer.METHODS: In this study, 182 patients with stage IV and non-surgical gastric cancer were retrospectively analyzed to evaluate the effects of TCM integrated with chemotherapy. Among the 182 cases, 88 cases received integrated therapy consisting of TCM and chemotherapy, while 94 cases received chemotherapy alone. The overall survival and Karnofsky performance status(KPS) score were measured as the main outcome.RESULTS: The median overall survival of the integrated therapy group and chemotherapy group were 16.9 and 10.5 months, respectively. The 1-, 3-and 5-year survival rates of integrated therapy group vs. chemotherapy group were 70% vs. 32%, 18% vs. 4%, and 11% vs. 0%, respectively. There was a significant difference between the two groups(χ2 = 42.244, P < 0.001). After six-month treatment, KPS scores of the integrated therapy group and the chemotherapy group were 75.00 ± 14.78 and 60.64 ± 21.39, respectively(P < 0.001). The Cox regression analysis showed that TCM treatment is a protective factor for patients' overall survival. CONCLUSION: This study demonstrated that TCM integrated with chemotherapy may prolong overall survival and improve survival rate and life quality of patients with stage IV non-surgical gastric cancer. | xuan liu li-juan xiu jian-peng jiao jing zhao ying zhao ye lu jun shi yong-jin li min ye yu-fang gu xiao-wei wang jing-yu xu ci-an zhang yong-ying liu yun luo xiao-qiang yue | 2017 | Journal of Integrative Medicine2017，15，6： | 18 |
| 4 | Esophageal Functional Changes in Obstructive Sleep Apnea/Hypopnea Syndrome and Their Impact on Laryngopharyngeal Reflux Disease显示文摘 | Yue Qu Jing-Ying Ye De-Min Han Li Zheng Xin Cao Yu-Huan Zhang Xiu Ding | 2015 | Chinese Medical Journal2015，，16： | 14 |
| 5 | Photodegradation of amoxicillin by catalyzed Fe^(3+)/H_2O_2 process显示文摘Three oxidation processes of UV-Fe3+(EDTA)/H2O2(UV:ultraviolet light;EDTA:ethylenediaminetetraacetic acid),UV-Fe3+/H2O2 and Fe3+/H2O2 were simultaneously investigated for the degradation of amoxicillin at pH 7.0.The results indicated that,100% amoxicillin degradation and 81.9% chemical oxygen demand(CODCr) removal could be achieved in the UV-Fe3+(EDTA)/H2O2 process.The treatment efficiency of amoxicillin and CODCr removal were found to decrease to 59.0% and 43.0% in the UV-Fe3+/H2O2 process;39.6% and 31.3% in the Fe3+/H2O2 process.Moreover,the results of biodegradability(biological oxygen demand(BOD5)/CODCr ratio) revealed that the UV-Fe3+(EDTA)/H2O2 process was a promising strategy to degrade amoxicillin as the biodegradability of the effuent was improved to 0.45,compared with the cases of UV-Fe3+/H2O2(0.25) and Fe3+/H2O2(0.10) processes.Therefore,it could be deduced that EDTA and UV light performed synergetic catalytic effect on the Fe3+/H2O2 process,enhancing the treatment efficiency.The degradation mechanisms were also investigated via UV-Vis spectra,and high performance liquid chromatography-mass spectra.The degradation pathway of amoxicillin was further proposed. | Xiaoming Li Tingting Shen Dongbo Wang Xiu Yue Xian Liu Qi Yang Jianbin Cao Wei Zheng Guangming Zeng | 2012 | Journal of Environmental Sciences2012，24，2： | 3 |
| 6 | New Diterpenoid Alkaloids from Spiraea fritschiana var. parvifolia显示文摘 | Min LI Xiu Bao DU Yue Mao SHEN Bin Gui WANG Xiao Jiang HAO ( The Beijing Institute of Pharmaceutical Chemistry, Beijing 102205 Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica. Kunming 650204)Abstrcat: Two new C20 hetisine | 1999 | Chinese Chemical Letters1999，10，10： | 3 |
| 7 | Factors associated with upstaging in patients preoperatively diagnosed with ductal carcinoma in situ by core needle biopsy显示文摘Objective: Patients preoperatively diagnosed with ductal carcinoma in situ(DCIS) by core needle biopsy(CNB) exhibit a significant risk for upstaging on final pathology, which leads to major concerns of whether axillary staging is required at the primary operation. The present study aimed to identify clinicopathological factors associated with upstaging in patients preoperatively diagnosed with DCIS by CNB.Methods: The present study enrolled 604 patients(cN0 M0) with a preoperative diagnosis of pure DCIS by CNB, who underwent axillary staging between August 2006 and December 2015, at Fudan University Shanghai Cancer Center(Shanghai, China).Predictive factors of upstaging were analyzed retrospectively.Results: Of the 604 patients, 20.03%(n = 121) and 31.95%(n = 193) were upstaged to DCIS with microinvasion(DCISM) and invasive breast cancer(IBC) on final pathology, respectively. Larger tumor size on ultrasonography(> 2 cm) was independently associated with upstaging [odds ratio(OR) 1.558, P = 0.014]. Additionally, patients in lower breast imaging reporting and data system(BI-RADS) categories were less likely to be upstaged(4 B vs. 5: OR 0.435, P = 0.002;4 C vs. 5: OR 0.502, P = 0.001). Overall,axillary metastasis occurred in 6.79%(n = 41) of patients. Among patients with axillary metastasis, 1.38%(4/290), 3.31%(4/121)and 17.10%(33/193) were in the DCIS, DCISM, and IBC groups, respectively.Conclusions: For patients initially diagnosed with DCIS by CNB, larger tumor size on ultrasonography(> 2 cm) and higher BIRADS category were independent predictive factors of upstaging on final pathology. Thus, axillary staging in patients with smaller tumor sizes and lower BI-RADS category may be omitted, with little downstream risk for upstaging. | Jing Si Benlong Yang Rong Guo Naisi Huang Chenlian Quan Linxiaoxi Ma Bingqiu Xiu Yun Cao Yue Tang Linxiao Shen Jiajian Chen Jiong Wu | 2019 | Cancer Biology & Medicine2019，16，2： | 3 |
| 8 | Inequalities on the Inner Radius of Univalency and the Norm of Pre-Schwarzian Derivative显示文摘在这篇论文,我们得到借助于 pre-Schwarzian 衍生物的标准导出的 Schwarzian 的 univalency 的内部半径的更低的界限。而且,我们使用通用 Teichmuller 空间的理论解释它在在 pre-Schwarzian 衍生物嵌入的通用 Teichmuller 空间定义的 Schwarzian 衍生物和标准嵌入的通用 Teichmuller 空间显示出在内部半径之间的关系的几何意思。 | Tao CHENG Yue Ming KANG Ji Xiu CHEN | 2009 | Acta Mathematica Sinica,English Series2009，25，1： | 3 |
| 9 | Network pharmacology-based approach to investigate the mechanisms of Yiyi Fuzi Baijiang Powder in the treatment of malignant tumors显示文摘目的:运用网络药理学的方法筛选中国东汉医学大家张仲景的薏苡附子败酱散的主要有效成分,预测其有效成分的作用靶点及靶点相关疾病;探讨其通过“多成分-多靶点-多通路”效应模型治疗相关疾病的作用机制。方法:通过中药化学成分数据库及文献,检索薏苡附子败酱散的化学成分,并依据TCMSP数据库的口服生物利用度和类药性指数筛选出主要有效成分。其后基于Drugbank和TCMSP数据库筛选出所有有效成分的作用靶点,利用TCMSP和TCMID数据库预测靶点相关的疾病种类,并依据国际疾病分类编码ICD-10分类。利用Cytoscape软件构建薏苡附子败酱散的主要有效成分-靶点-疾病网络图,分析其网络拓扑结构,并通过DAVID数据库对该方所涵盖的所有靶点进行生物学功能和KEGG通路进行分析。结果:本研究共筛选出薏苡附子败酱散有效成分24种,相关靶点133个,相关疾病305种,炎症、疼痛和肿瘤是其治疗的主要疾病,并可调节神经活性的配体-受体相互作用、TNF信号通路、PI3K-Akt信号通路等发挥治疗肠痈和肿瘤的作用。结论:本研究初步证实了炎症、疼痛和肿瘤是薏苡附子败酱散治疗的主要疾病,该结果不仅证实了张仲景使用薏苡附子败酱散治疗肠痈的初衷,更为该古方可能用于治疗恶性肿瘤提供科学依据。 | Shang-Jin Song Ren-Jie Xu Li-Juan Xiu Xuan Liu Xiao-Qiang Yue | 2018 | Traditional Medicine Research2018，3，6： | 3 |
| 10 | Nuclear pseudogenes of mitochondrial DNA as a variable part of the human genome显示文摘INTRODUCTIONNuclearpseudogenesofmitochondrial(mt)DNAwereinitiallydiscoveredintheearly80's[1--6].However,mechanismsforthegenerationofmtDNApseudogenesarestillnotclearandmayvaryindifferentcases.BothRNA--[7--8]andDNAmediated[9--11]processeshavebeensugges... | YUAN JIN DUO JIN XIU SHI GUANG XUNMENG LI GUO AN GENG XI HU( Shanghai Institute of Cell Biology and the ShanghaiLife Science Center, Chinese Academy of Sciences,320 Yue Yang Road, Shanghai 200031, China)( Department of Biology, Shandong Normal Univers | 1999 | Cell Research1999，9，4： | 3 |
| 11 | Ziyin Huatan Recipe, a Chinese herbal compound, inhibits migration and invasion of gastric cancer by upregulating RUNX3 expression显示文摘Objectives: Ziyin Huatan Recipe(ZYHT), a traditional Chinese medicine comprised of Lilii Bulbus, Pinelliae Rhizoma, and Hedyotis Diffusa, has shown promise in treating gastric cancer(GC). However, its potential mechanism has not yet been clearly addressed. This study aimed to predict targets and molecular mechanisms of ZYHT in treating GC by network pharmacology analysis and to explore the role of ZYHT in GC both in vitro and in vivo.Methods: Targets and molecular mechanisms of ZYHT were predicted via network pharmacology analysis. The effects of ZYHT on the expression of metastasis-associated targets were further validated by Western blot and quantitative real-time polymerase chain reaction. To explore the specific molecular mechanisms of the effects of ZYHT on migration and invasion, the runt-related transcription factor 3(RUNX3) gene was knocked out by clustered regularly interspaced short palindromic repeats/Cas9, and lentiviral vectors were transfected into SGC-7901 cells. Then lung metastasis model of GC in nude mice was established to explore the anti-metastasis effect of ZYHT. Western blot and immunohistochemistry were used to explore the impact of ZYHT on the expression of metastasis-related proteins with or without RUNX3 gene.Results: The network pharmacology analysis showed that ZYHT might inhibit focal adhesion, migration,invasion and metastasis of GC. ZYHT inhibited the proliferation, migration and invasion of GC cells in vitro via regulating the expression of metastasis-associated targets. Knocking out RUNX3 almost completely reversed the cell phenotypes(migration and invasion) and protein expression levels elicited by ZYHT.In vivo studies showed that ZYHT inhibited the metastasis of GC cells to the lung and prolonged the survival time of the nude mice. Knocking out RUNX3 partly reversed the metastasis of GC cells to the lung and the protein expression levels elicited by ZYHT.Conclusion: ZYHT can effectively inhibit the invasion and migration of GC in vitro and in vivo, and its molecular mechanism may relate to the upregulation of RUNX3 expression. | Shang-jin Song Xuan Liu Qing Ji Da-zhi Sun Li-juan Xiu Jing-yu Xu Xiao-qiang Yue | 2022 | Journal of Integrative Medicine2022，20，4： | 2 |
| 12 | Production of Fibres from Lunar Soil:Feasibility,Applicability and Future Perspectives显示文摘The construction of a lunar base is considered to be an important step towards deep-space exploration by humanity,and will rely on the utilisation of in situ lunar resources.In this paper,we discuss the current knowledge on the feasibility of converting lunar soil to high-performance fibres that can be used for the construction of a lunar base.This fibre would be combined with further portions of lunar soil to generate fibre-reinforced composites,which is utilized as multi-functional materials for lunar base construction.We discuss and analyse the latest findings regarding the composition of lunar soil simulants and their fibrisation properties,and techniques for fibre spinning and system integration.Finally,we suggest how the achievements made so far could be applied to the construction of a lunar base. | Ze‑Shi Guo Dan Xing Xiong‑Yu Xi Xiu Yue Cun‑Guang Liang Bin Hao Qingbin Zheng Sergey I.Gutnikov Bogdan I.Lazoryak Peng‑Cheng Ma | 2022 | Advanced Fiber Materials2022，4，5： | 2 |
| 13 | A rapid and cheap protocol for preparation of PCR templates in peanut显示文摘 | Chuan Tang Wang Xiu Zhen Wang Yue Yi Tang | 2009 | Electronic Journal of Biotechnoiogy2009，12，2： | 1 |
| 14 | Preparation and properties of biodegradable poly (propyl- ene carbonate )/starch composites 显示文摘 | GE Xiang - cai LI Xiu - hua MENG Yue - zhong | 2004 | Polym Eng Sci2004，44，11： | 1 |
| 15 | Morphology and texture evolution of FeCrAlTi–Y 2 O 3 foil fabricated by EBPVD显示文摘 | Xiu Lin Xiaodong He Yue Sun Yibin Li Guangping Song Xinyan Li Jiazhen Zhang | 2010 | Surface & Coatings Technology2010，，1： | 1 |
| 16 | Novel mutations in RSPH4A and TTN genes lead to primary ciliary dyskinesia-hereditary myopathy with early respiratory failure overlap syndrome显示文摘Primary ciliary dyskinesia(PCD)is an autosomal recessive disease caused by defects in motile cilia and clinically characterized by bronchiectasis,situs inversus,nasosinusitis,recurrent respiratory infections,tympanitis,and/or male infertility.In PCD,impaired function or structure of motile cilia leads to abnormality of mucociliary clearance。 | Mengjie Feng Xiu Yu Yongjian Yue Jiacheng Zhong Lingwei Wang | 2023 | Genes & Diseases2023，10，3： | 1 |
| 17 | Graded composition and doping p-i-n Al_(x)Ga_(1−x)As/GaAs detector for unbiased voltage operation显示文摘p-i-n Al_(x)Ga_(1−x)As/GaAs detectors with graded compositions and graded doping were grown and prepared.From the current-voltage and capacitance-voltage measurement results,the devices had good p-n junction diode characteristics,and the electric field strength under an unbiased voltage was 1.7×10^(5) Vcm^(-1).The full width at half maximum and charge collection efficiency of the detectors obtained from energy spectrum measurements of 5.48-MeV alpha particles were 3.04 and approximately 93%,respectively.In this study,we created the most advanced and promising state-of-the-art unbiased detector reported to date. | Zhi-Fu Zhu Ji-Jun Zou Zhi-Jia Sun He Huang Qing-Lei Xiu Zhong-Ming Zhang Yong Gan Chen-Xian Guo Shao-Tang Wang Xiu-Ping Yue Guo-Li Kong | 2022 | Nuclear Science and Techniques2022，33，7： | 1 |
| 18 | Comparison of Two Different Rolling Processes on Microstructure and Properties of Ferrite-Bainite Dual-Phase Pipeline Steels显示文摘 | Hu Yue Yue Zuo Xiu Rong Li Ru Tao Wang Zhen Wei | 2011 | Advanced Materials Research2011，，197： | 1 |
| 19 | The Hand Making of Radius Fillers and the Establishment of its Evaluative Requirements显示文摘 | Hai Lei Wang Mei Rong Xiong Yue Xin Duan Jin Yang Dong Xiu Yan Shao Chen Xu | 2014 | Advanced Materials Research2014，，936： | 1 |
| 20 | Interleukin-8 secretion by ovarian cancer cells increases anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion显示文摘 | Yue Wang Rui Cheng Xu Xiao Lei Zhang Xiu Long Niu Ye Qu Ling Zhi Li Xiang Yan Meng | 2012 | Cytokine2012，，1： | 1 |
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