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| 1 | Thoughts on the Development of Bridge Technology in China显示文摘In the history of bridge engineering, demand has always been the primary driving force for development. Driven by the huge demand for construction since China’s reform and opening-up, Chinese bridge has leapt forward both quantitatively and qualitatively in three major stages, by completing the transition from “follower” to “competitor,” and nally to “leader.” A new future is emerging for Chinese bridge engi- neering. As an important part of China’s transportation infrastructure, the bridge engineering industry is facing challenges in this new era on how to support the construction of a new form of transportation. This paper provides a summary of the status of bridge technology in China, based on a basic analysis of stock demand, incremental demand, and management demand. It is our belief that the Chinese bridge engi- neering industry must ful ll three outstanding requirements: construction ef ciency, management effec- tiveness, and long-term service. Intelligent technology based on information technology provides a new opportunity for innovation in bridge engineering. As a result, the development path of bridge engineering needs to be changed. This paper puts forward the idea of developing a third-generation bridge project that is characterized by intelligence, and discusses this project’s implications, development focus, and plan. In this way, this work provides a direction for the improvement of the core competitiveness of China’s bridge engineering industry. | Xuhong Zhou Xigang Zhang | 2019 | Engineering2019，5，6： | 24 |
| 2 | Cigarette Smoking Increases Risk for Incident Metabolic Syndrome in Chinese Men—Shanghai Diabetes Study显示文摘Objective To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.Methods A total of 693 men with no MetS at baseline were followed for 2.9‐5.5 years.Subjects were divided into nonsmokers,ex‐smokers,and current smokers according to baseline smoking status.Results After adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR index,and BMI at baseline and weight change,current smokers were dose‐dependently associated with increased risk for developing new MetS compared with nonsmokers.The odds ratio (OR) was 2.131 (95% CI,1.264,3.592;P<0.01) for the NCEPIII definition or 3.083 (95% CI,1.807,5.295;P<0.01) for the JCDCG definition of MetS.Ex‐smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition.Compared with nonsmokers,current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL‐C.Conclusion Smoking is a risk factor for developing MetS in Chinese men after adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR,BMI,and weight change.This could be due to an increased incidence of dyslipidemia.Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition. | ZHU YunXia ZHANG MingLiang HOU XuHong LU JunXi PENG LiangPu GU HuiLin WANG Chen JIA WeiPing | 2011 | Biomedical and Environmental Sciences2011，24，5： | 13 |
| 3 | Effects of sulfur fertilization and short-term high temperature on wheat grain production and wheat flour proteins显示文摘The content of wheat flour proteins affects the quality of wheat flour. Sulfur nutrition in wheat can change the protein content of the flour. The inconsistency and instability of wheat grain quality during grain filling under high temperature stress(HTS) are a major challenge to the production of high-quality wheat. The effects of sulfur fertilization and HTS on wheat flour protein and its components are unknown. In this study, treatments varying two factors: sulfur fertilization and exposure to short-term HTS, at 20 days postanthesis, were applied to two wheat cultivars with differing gluten types. Plants of a stronggluten wheat(Gaoyou 2018) and a medium-gluten wheat(Zhongmai 8) were grown in pots in Beijing in 2015–2017. HTS significantly increased the contents of total protein, albumin,gliadin, glutenin, Cys, and Met in wheat kernels, but reduced grain yield, grain weight,protein yield, globulin content, and total starch accumulation. The HTS-induced increase in total protein amount was closely associated with nitrate reductase(NR) and glutamine synthetase(GS) activities in flag leaves. Sulfur fertilization increased grain and protein yields; grain weight; total protein, albumin, gliadin, glutenin, and globulin contents; protein yield; total starch; Cys, Met; and NR and GS activities. HTS and sulfur fertilization had larger effects on the strong-than on the medium-gluten cultivar. Sulfur fertilization also alleviated the negative effects of HTS on grain yield, protein yield, and starch content.Thus, growing wheat with additional soil sulfur can improve the quality of the flour. | Zhiqiang Tao Xuhong Chang Demei Wang Yanjie Wang Shaokang Ma Yushuang Yang Guangcai Zhao | 2018 | The Crop Journal2018，6，4： | 11 |
| 4 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 5 | Green Production Technology of the Monomer of Nylon-6: Caprolactam显示文摘 | Baoning Zong Bin Sun Shibiao Cheng Xuhong Mu Keyong Yang Junqi Zhao Xiaoxin Zhang Wei Wu | 2017 | Engineering2017，3，3： | 9 |
| 6 | Effects of tridimensional uniform sowing on water consumption, nitrogen use, and yield in winter wheat显示文摘Wheat is a staple crop worldwide, but yields may diminish as climate change causes increasingly unpredictable patterns of precipitation and soil nutrient availability. Farmers are thus challenged to maximize planting efficiency to increase yield, while also improving their resource use efficiency. In this study the effectiveness of tridimensional uniform sowing was tested across a range of planting densities for winter wheat crops on the North China Plain. Tridimensional uniform sowing was tested against conventional drilling at three planting densities (180 × 104, 270 × 104, and 360 × 104 plants ha 1) and assessed for water consumption, biomass, nitrogen uptake and allocation, and aspects of yield. The tridimensional uniform sowing treatment outperformed the conventional drilling treatment in most metrics and at most planting densities, while performing markedly better at higher planting densities. Water consumption decreased and nitrogen efficiency increased. Tiller number and percentage of productive tillers, leaf area index, dry weight, and yield increased without a significant decline in grain protein. Nitrogen allocation was more efficient under tridimensional uniform sowing than with conventional drilling, and also varied according to annual precipitation and planting density. Both yield and grain protein contents were significantly correlated with the amount of pre-anthesis accumu- lated nitrogen translocated from vegetative organs to kernels after anthesis. Overall, a density of 270 × 104 plants ha 1 provided the highest water use efficiency and grain yield. Tridimensional uniform sowing will benefit farmers by forming stronger overall crops, promoting the coordinated improvement of yield, nitrogen uptake and efficiency, and increasing grain protein content at higher planting densities. | Zhiqiang Tao Shaokang Ma Xuhong Chang Demei Wang Yanjie Wang Yushuang Yang Guangcai Zhao Jiancang Yang | 2019 | The Crop Journal2019，7，4： | 8 |
| 7 | Catastrophe Model of Steam Flow Excitation Vibration in Steam Turbine Governing Stage显示文摘汽流激振是影响大型汽轮机组安全运行的主要故障之一。根据突变理论、非线性振动理论以及流体动力学,从机理分析的角度出发,对汽轮机调节级在部分进汽下导致的汽流激振突变性能进行了定量分析。建立了部分进汽情况下调节级气流激振力模型,以及考虑汽流激振力的调节级非线性动力学模型,通过基于突变理论的推导,得到了调节级汽流激振的尖点突变流形和分岔集,确定了系统汽流激振突变的影响因子,讨论了振幅突变与影响因子的相关性,划分了系统工作的突变区域。最后,利用数值计算方法对汽流激振的幅值响应进行了分析,分析结果验证了基于突变理论的汽流激振突变分析方法的正确性。研究成果为汽轮机汽流激振突变性能的研究提供了一条新的途径。 | LI Jianlan GUO Xuhong YU Chen HUANG Shuhong | 2013 | 中国电机工程学报2013，33，11： | 8 |
| 8 | Spatial-temporal pattern changes of main agriculture natural disasters in China during 1990-2011显示文摘China is a disaster prone country, and a comprehensive understanding of change of disasters is very important for China's agricultural development. In this study, statistical techniques and geographic information system tools are employed to quantify the main agriculture disasters changes and effects on grain production in China during the period of 1990–2011. The results show that China's grain production was severely affected by disasters including drought, flood, hail, frost and typhoon. The annual area covered by these disasters reached up to 48.7×106 ha during the study period, which accounted for 44.8% of the total sown area, and about 55.1% of the per unit area grain yield change was caused by disasters. In addition, all of the disasters showed high variability, different changing trends, and spatial distribution. Drought, flood, and hail showed significantly decreasing trends, while frost and typhoon showed increasing trends. Drought and flood showed gradual changes and were distributed across the country, and disasters became more diversified from north to south. Drought was the dominated disaster type in northern China, while flood was the most important disaster type in the southern part. Hail was mainly observed in central and northern China, and frost was mainly distributed in southern China. Typhoon was greatly limited to the southeast coast. Furthermore, the resilience of grain production of each province was quite different, especially in several major grain producing areas, such as Shandong, Liaoning, Jilin and Jiangsu, where grain production was seriously affected by disasters. One reason for the difference of resilience of grain production was that grain production was marginalized in developed provinces when the economy underwent rapid development. For China's agricultural development and grain security, we suggest that governments should place more emphasis on grain production, and invest more money in disaster prevention and mitigation, especially in the major grain producing provinces. | DU Xindong JIN Xiaobin YANG Xilian YANG Xuhong XIANG Xiaomin | 2015 | Journal of Geographical Sciences2015，25，4： | 8 |
| 9 | Effects of Tai Ji Exercise on Bone Structure and Function显示文摘To evaluated the effects of the 24 movements Tai Ji ex ercise on bone structure and function. Broadband Ultrsonic Attenuation (BUA) and velocit y of sound (VOS), bone formation marker Osteocalcin (OSTN) and bone resorption m arkers urinary Pyridum crosslinks (PYR and D-PYR) were studied before and after four months of Tai Ji exercise. Improved bone structure and increased bone dens ity in menopausal women were reflected by BUA results. The increased BUA appear s to be associated with increased bone formation rather than decreased bone reso rption. | XuHong DavidLawson | 2005 | 中国运动医学杂志2005，24，1： | 7 |
| 10 | Does copper reduce cadmium uptake by different rice genotypes?显示文摘一个水栽法实验被进行在镉(Cd ) 上调查铜(Cu ) 的效果,钙(Ca ) ,铁(Fe ) ,和锌(Zn ) 由几米饭遗传型的举起。实验在营养液与四米饭遗传型和 Cu 和 Cd 的二个层次作为 2 × 2 × 4 阶乘被执行。植物与控制环境在一个生长房间被种。结果显示出不同米饭遗传型的生物资源之间的重要差别(P <
0.001 ) 。在答案的 Cd 和 Cu 集中没在生物资源上有重要效果。Cu 的增加显著地减少了由米饭的射击和根的 Cd 举起(P <
0.001 ) 。Cd 集中显著地没由植物影响 Ca 举起,而 Cu 集中做了(P = 0.034 ) 。有由射击和根的 Fe 举起上的 Cd 的重要影响(P <
0.001, P = 0.003,分别地) 。Zn 举起作为在射击增加的 Cd 和 Cu 的增加显著地减少了。我们断定 Cu 在 Cd 举起上有重要影响。可能的机制被讨论。 | CUI Yujing ZHANG Xuhong ZHU Yongguan | 2008 | Journal of Environmental Sciences2008，20，3： | 7 |
| 11 | Mechanical behavior of concrete-filled rectangular steel tubular composite truss bridge in the negative moment region显示文摘Concrete-filled rectangular steel tubular(CFRST)composite truss bridge is a new type of structure composed of a CFRST truss and concrete deck slab.This new type of bridge has the advantages of high structural force-transferring efficiency,rapid assembly construction speed and excellent total life cycle,which meets the construction concept of green,recyclable and sustainable development.Due to the broad application prospects,experiment on the flexural behavior of CFRST composite truss bridge in the negative moment region was reported by authors previously.This paper thus presents a finite element analysis(FEA)modelling verified by the reported test data to further investigate the detailed analytical behavior of this structure.The structural response and failure mechanism of CFRST composite truss beam in the negative moment region are studied.In addition,the important structural design parameters on the flexural performance of the CFRST composite truss beam are also investigated,including the height to span ratio,the brace-to-chord wall thickness ratio,the reinforcement ratio of steel reinforcements and prestressed tendons and the strength grade of concrete infill in chords.Finally,the reasonable structural design parameters range are proposed for the optimum design of the CFRST composite truss bridge. | Beichen Pu Xuhong Zhou Yongjian Liu Bin Liu Lei Jiang | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，5： | 6 |
| 12 | Highly sensitive and selective ratiometric fluorescent copper sensors: Different binding affinities modulated by three separate side chains of naphthalimide显示文摘A series of compounds 1-11 with different side chains of naphthalimide as fluorescent copper sensors were designed and synthesized. Compounds 1, 9, 10 and 11 presented a high selectivity to Cu2+ in a neutral aqueous environment. Here 1, 9 and 10 showed selectivity and affinity to Cu2+ with an association constant of about ~106. It gave somewhat response to Ag+, Co2+, Ni2+ and Fe2+ while 1 detected copper. 9 and 10 displayed better selectivity by changing their hydrophobic side chains to the hydrophilic ones on imide moieties. 11, with one flexible side chain, showed high selectivity and an association constant (Ka = 2.2 × 108), which were much higher than those of 1, 9 and 10. These results indicated that the selectivity and affinity could be improved by changing side chains of naphthalimide. That might provide a novel strategy or method for the development of fluorescent sensors. | XU YuFang LU Feng XU ZhaoChao CHENG TanYu QIAN XuHong | 2009 | Science China Chemistry2009，52，6： | 4 |
| 13 | Facile preparation of low swelling,high strength,self-healing and pH-responsive hydrogels based on the triple-network structure显示文摘A polyacrylic acid(PAA)/gelatin(Gela)/polyvinyl alcohol(PVA)hydrogel was prepared by copolymerization,cooling,and freezing/thawing methods.This triplenetwork(TN)structure hydrogel displayed superior mechanical properties,low swelling ratio and self-healing properties,The superior mechanical properties are attributed to the triple helix association of Gela and PVA crystallites by reversible hydrogen bonding.The characterization results indicated that the fracture stress and the strain were 808 kPa and 370% respectively,while the compression strength could reach 4443 kPa and the compressive modulus was up to 39 MPa under the deformation of 90%.The hydrogen bonding in PVA contributed to maintain and improve the self-healing ability of hydrogels.Every type of hydrogels exhibited a higher swelling ratio under alkaline conditions,and the swelling ratios of PAA,PAA/PVA and PAA/Gela hydrogels were 27.71,12.30 and 9.09,respectively.The PAA/Gela/PVA TN hydrogel showed the lowest swelling ratio(6.57)among these hydrogels.These results indicate that the novel TN hydrogels possess good environmental adaptability and have potential applications in the biomedical engineering and sensor field. | Zhicun WANG Xiaoman HAN Yixi WANG Kenan MEN Lin CUI Jianning WU Guihua MENG Zhiyong LIU Xuhong GUO | 2019 | Frontiers of Materials Science2019，13，1： | 4 |
| 14 | Reconstructing Spatial Distribution of Historical Cropland in China′s Traditional Cultivated Region: Methods and Case Study显示文摘As an important part of land use/cover change(LUCC), historical LUCC in long time series attracts much more attention from scholars. Currently, based on the view of combining the overall control of cropland area and ′top-down′ decision-making behaviors, here are two global historical land-use datasets, generally referred as the Sustainability and the Global Environment datasets(SAGE datasets) and History Database of the Global Environment datasets(HYDE datasets). However, at the regional level, these global datasets have coarse resolutions and inevitable errors. Considering various factors that influenced cropland distribution, including cropland connectivity and the limitation of natural and human factors, this study developed a reconstruction model of historical cropland based on constrained Cellular Automaton(CA) of ′bottom-up′. Then, an available labor force index is used as a proxy for the amount of cropland to inspect and calibrate these spatial patterns. Applied the reconstruction model to Shandong Province, we reconstructed its spatial distribution of cropland during 8 periods. The reconstructed results show that: 1) it is properly suitable for constrained CA to simulate and reconstruct the spatial distribution of cropland in traditional cultivated region of China; 2) compared with ′SAGE datasets′ and ′HYDE datasets′, this study have formed higher-resolution Boolean spatial distribution datasets of historical cropland with a more definitive concept of spatial pattern in terms of fractional format. | YANG Xuhong GUO Beibei JIN Xiaobin LONG Ying ZHOU Yinkang | 2015 | Chinese Geographical Science2015，25，5： | 4 |
| 15 | Farmland dataset reconstruction and farmland change analysis in China during 1661-1985显示文摘This research reconstructs China's provincial farmland dataset in the last 300 years(1661–1985) by applying factor correction, citing replacement, linear interpolation, cohesion and contrast, man-land relationship test, farming trend test, provincial administrative area adjustment, etc. on available farmland data based on China's current provincial administrative boundary. Based on this dataset, a quantitative analysis has been applied to study the farmland amount and its change characteristics at both national and provincial level. Three conclusions are derived:(1) Along with the rapid population growth, national farmland amount has increased by about 320% in the last 300 years from 424,480 km2 in the early Qing Dynasty to 1,368,600 km2 in 1985. Comparing with global and national farmland datasets, in terms of the overall trend of national farmland growth, very low deviation exists but significant variances do appear for some provinces.(2) At the beginning of the Qing Dynasty, China's farming activities mainly existed in the Yangtze River Plain, the North China Plain, the Guanzhong Basin and the Yinchuan Plain. Thereafter, reclamation activities expanded to outer agricultural areas. Regarding of the growth rate, national farmland increase can be divided into five phases. National policy, disasters, wars, and economic development, are the main factors affecting farmland changes.(3) Significant regional variances exist in farmland changes. In the space shaped by the average farmland amount and the average annual change rate of farmland, the nation can be divided into six areas. | JIN Xiaobin CAO Xue DU Xindong YANG Xuhong BAI Qing ZHOU Yinkang | 2015 | Journal of Geographical Sciences2015，25，9： | 4 |
| 16 | Cloning,expression and characterization of serine palmitoyltransferase(SPT)-like gene subunit(LCB2) from marine Emiliania huxleyi virus(Coccolithovirus)显示文摘The authors have isolated and characterized a novel serine palmitoyltransferase(SPT)-like gene in marine Emiliania huxleyi virus(EhV-99B1).The open-reading frame(ORF) of EhV99B1-SPT encoded a protein of 496 amino acids with a calculated molecular mass of 96 kDa and Ip 6.01.The results of sequence analysis showed that there was about 31%-45% identity in amino acid sequence with other organisms.The maximum likelihood phylogenetic tree suggested that the EhV99B1-SPT gene possibly horizontally transferred from the eukaryote.Hydrophobic profiles of deduced amino acid sequences suggested a hydrophobic,globular and membrane-associated protein with five transmembrane domains(TMDs) motifs.Several potential N-linked glycosylation sites were presented in SPT.These results suggested that EhV99B1-SPT was an integral endoplasmic reticulum membrane protein.Despite lower sequence identity,the secondary and three-dimensional structures predicted showed that the 'pocket' structure element composed of 2α-helices and 4βsheets was the catalytic center of this enzyme,with a typical conserved 'TFTKSFG' active site in the N-terminal region and was very close to those of prokaryotic organisms.However,the N-terminal domain of EhV99B1-SPT most closely resembled the LCB2 catalysis subunit and the C-terminal domain most closely resembled the LCB1 regulatory subunit of other organisms which together formed a spherical molecule.This 'chimera' was highly similar to the prokaryotic homologous SPT.For a functional identification,the EhV99B1-LCB2 subunit gene was expressed in Escherichia coli,which resulted in significant accumulation of new sphingolipid in E.coli cells. | LIU Xuhong ZHENG Tianling CAI Yiqin LIU Jingwen | 2012 | Acta Oceanologica Sinica2012，31，6： | 4 |
| 17 | Heteroatom-doped porous carbon from methyl orange dye wastewater for oxygen reduction显示文摘Banana peel-derived porous carbon(BPPC) was prepared from banana peel and used as an adsorbent for methyl orange(MO) wastewater removal. BPPC-MO50 is a N,S-doped BPPC obtained via secondary carbonization. The BPPC-MO50 exhibited a high specific surface area of1774.3 m^2/g. Heteroatom-doped porous carbon(PC) was successfully synthesized from the BPPC absorbed MO at high temperature and used for oxygen reduction. The BPPC-MO50 displayed the highest ORR onset potential among all carbon-based electrocatalysts, i.e., 0.93 V vs.reversible hydrogen electrode(RHE). This is the first report to describe porous carbon-activated materials from agriculture and forestry waste that is used for adsorption of dyes from wastewater via an enhanced heteroatom(N,S) content. These results may contribute to the sustainable development of dye wastewater treatment by transforming saturated PC into an effective material and has potential applications in fuel cells or as energy sources. | Yiqing Wang Mingyuan Zhu Yingchun Li Mengjuan Zhang Xueyan Xue Yulin Shi Bin Dai Xuhong Guo Feng Yu | 2018 | Green Energy & Environment2018，3，2： | 4 |
| 18 | Microstructure and Mechanical Behavior of in Situ Primary Si/Mg_2Si Locally Reinforced Aluminum Matrix Composites Piston by Centrifugal Casting显示文摘Al-Si pistons are frequently damaged by burning piston top surface due to elevated combustion temperature, and by rubbing the first ring groove against the engine cylinder liner. To prevent piston from these damages, some technologies were invented, such as mounting high Ni cast iron ring around the first ring groove in Al alloy piston body and thermal resistant steel on piston top surface, and fabricating Al composite pistons by squeeze casting for enhancing the whole or local piston performance. In this paper, composite pistons locally reinforced with in situ primary Si and primary Mg2Si particles are fabricated by centrifugal casting. The microstructure characteristics, hardness and wear resistance of the composite piston are investigated and the motion characteristic of the in situ particles in centrifugal field is analyzed. The results of the experiments show that primary Si and Mg2Si particles mix up with each other in melt and segregate at the regions of piston top and piston ring grooves under the effect of centrifugal force. Particulate reinforced regions have a higher hardness and better wear resistance compared with the unreinforced regions and this performance increases after heat treatment. The analysis result of particle movement shows that, primary Si and primary Mg2Si particles move at approximately the same velocity in the centrifugal field, because of the growth of primary Si and fusion after colliding between primary Si particles, which compromised the velocity difference of primary Si and primary Mg2Si particles caused by the difference of their densities. Research results have some theory significance and applicative value of project in development of new aluminum matrix composites piston products. | HAO Xuhong LIU Changming PAN Dengliang | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 3 |
| 19 | Magnetically stabilized bed reactor for selective hydrogenation of olefins in reformate with amorphous nickel alloy catalyst显示文摘A magnetically stabilized bed (MSB) reactor for selective hydrogenation of olefins in reformate was developed by combining the advantages of MSB and amorphous nickel alloy catalyst. The effects of operating conditions, such as temperature, pressure, liquid space velocity, hydrogen-to-oil ratio, and magnetic field intensity on the reaction were studied. A mathematical model of MSB reactor for hydrogenation of olefins in reformate was established. A reforming flow scheme with a post-hydrogenation MSB reactor was proposed. Finally, MSB hydrogenation was compared with clay treatment and conventional post-hydrogenation. | Xuhong Mu Enze Min | 2007 | China Particuology2007，5，1： | 3 |
| 20 | Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization显示文摘NF-κB, a family of transcription factors regulating diverse biological processes including immune responses, is activated by canonical and noncanonical pathways based on degradation of IκBα and processing of the IκB-like protein p100, respectively. Although p100 responds to noncanonical NF-κB stimuli for processing, it does not undergo degradation, but rather becomes accumulated, along with canonical NF-κB activation. We show here that the stability of p100 is tightly controlled by a deubiquitinase, Otub1. Otub1 deficiency not only promotes signal-induced p100 processing and noncanonical NF-κB activation but also causes steady-state p100 degradation, leading to aberrant NF-κB activation in the canonical pathway. B-cell-conditional deletion of Otub1 results in B-cell hyperplasia, antibody hyper-production, and lupus-like autoimmunity. Otub1-deficient B cells display aberrantly activated phenotypes and overproduce the cytokine IL-6, contributing to autoimmunity induction. Thus, maintenance of p100 stability by Otub1 serves as an unusual mechanism of NF-κB regulation that prevents autoimmunity. | Yanchuan Li Jin-Young Yang Xiaoping Xie Zuliang Jie Lingyun Zhang Jianhong Shi Daniel Lin Meidi Gu Xiaofei Zhou Haiyan S. Li Stephanie S. Watowich Antrix Jain Sung Yun Jung Jun Qin Xuhong Cheng Shao-Cong Sun | 2019 | Cell Research2019，29，6： | 3 |
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