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| 1 | SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway显示文摘当严重急性呼吸症候群日冕病毒(SARS-CoV ) 开始被认为与质膜通过直接熔化进入房间时,更最近的证据建议那个病毒条目可以也包含 endocytosis。我们发现了那 SARS-CoV 进入房间经由 pH 依赖并且受体依赖者 endocytosis。有任何一个 SARS-CoV 尖铁蛋白质或忍受尖铁的假病毒的房间的治疗导致了变换血管收缩素的酶的 translocation 2 (ACE2 ) , SARS-CoV 的功能的受体,从房间表面到内涵体。另外,忍受尖铁的假病毒和 1 在内涵体被发现到 colocalize 的早内涵体抗原。用象 caveolin-1 colocalization 学习一样的特定的 endocytic 小径禁止者和主导否定的 Eps15 的进一步的分析建议那个病毒条目被 clathrin 独立、 caveolae 独立的机制调停。而且,在质膜的微域,它被显示出到为许多生理的发信号小径作为平台扮演的充满胆固醇、 sphingolipid 富有的类脂化合物木排,被显示涉及病毒入口。SARS-CoV 的 Endocytic 入口可以扩展这里的 SARS-CoV 感染,和我们的调查结果的细胞的范围贡献 SARS-CoV 致病的理解,为抗病毒的药研究提供新信息。 | Wang,H Yang,P Liu,K Guo,F Zhang,Y Zhang,G Jiang,C | 2008 | Cell Research2008，18，2： | 50 |
| 2 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 3 | Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘 | Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 4 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 5 | Enantioselective electrocatalytic epoxidation of olefins by chiral manganese Schiffbase complexes显示文摘 | Guo P Wong K Y | 1999 | Electrochem Commun1999，1，： | 2 |
| 6 | Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘 | Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J | | 0，，： | 2 |
| 7 | E-subvarieties of the variety of idempotent semirings显示文摘 | Zhao X Z Shum K P Guo Y Q | 2001 | Algebra Universalis2001，46，： | 1 |
| 8 | Nonlinear seismic soil-pile-structure interactions: Shaking table tests and FEM analyses显示文摘 | Chau K T Shen C Y Guo X | 2009 | Soil Dynamic and Earthquake Engineering2009，29，： | 1 |
| 9 | Introduction for the Theory of Error-Eliminating显示文摘 | GUO K Z LIU S Y | 1996 | Advances in Modeling& Analysis A:General Mathematical & Computer Tools1996，39，34： | 1 |
| 10 | Immobilization of platinated and iodinated oligonucleotides on carbon nanotubes显示文摘 | Tsang S C Guo Z Chen Y K | 1997 | Angew Chem Int Ed Engl1997，36，： | 1 |
| 11 | Temperature-Dependent Photoluminescence of ZnO Nanorods Prepared by a Simple Solution Route显示文摘 | Lv Y Z Zhang Y H Li C P Ren L R Guo L Xu H B Ding L Yang C L Ge W K and Yang S H | 2007 | Luminescence2007，，： | 1 |
| 12 | Effects of Carbon Nanotube Functionalization on the Mechanical and Thermal Properties of Epoxy Composites 显示文摘 | Yang K Gu M Y Guo Y P | | Carbon0，47，7： | 1 |
| 13 | Mitofusin2 triggers vascular smooth cell apoptosis vis mitochondrial death pathway 显示文摘 | Guo X M Chen K H Guo Y H | 2007 | Circ Res2007，101，11： | 1 |
| 14 | Comparisons A- mong Contemporary Glacial Isostatic Adjustment Models显示文摘 | Guo J Y Huang Z W Shum C K | 2012 | J Geodyn2012，，3： | 1 |
| 15 | Sensitive and rapid detection of the new Delhi metallo-beta- lactamase gene by loop-mediated isothermal amplification 显示文摘 | Liu W Zou D Li Y Wang X He X Wei X Shao C Li X Shang W Yu K Liu D Li Y Guo J Yin Z Yuan J | 2012 | J Clin Microbiol2012，50，5： | 1 |
| 16 | limestone PAl2 composite 显示文摘 | Guo Y Jiang K Bourell D L | 2014 | Preparation and laser sintering of Polymer Testing2014，37，： | 1 |
| 17 | Phthalates and parabens in personal care products from China: Concentrations and human exposure显示文摘 | GUO Y WANG L KANNAN K | 2014 | Archives of Environmental Contamination and Toxicology2014，66，1： | 1 |
| 18 | Heterotrimeric G proteins regulate nitrogen-use efficiency in rice 显示文摘 | Sun H Y Qian Q Wu K Luo J J Wang S S Zhang C W Ma Y F Liu Q Huang X Z Yuan Q B Han R X Zhao M Dong G J Guo L B Zhu X D Gou Z H Wang W Wu Y J Lin H X Fu X D | 2014 | Nature Genetics2014，46，4： | 1 |
| 19 | Emerging HIV-1 epidemic in China in men who have sex with men显示文摘 | Choi K H Liu H Guo Y | 2003 | Lancet2003，361，： | 1 |
| 20 | Research on Laws of Security Risk-Error Logic System with Critical Point显示文摘 | GUO K Z LIU S Y | 2001 | Advances in Modeling & Analysis D2001，22，12： | 1 |
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