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| 1 | Expert consensus on the use of human serum albumin in critically ill patients显示文摘Introduction Human serum albumin(HSA)is a non-glycosylated,negatively charged,single-chain polypeptide composed of 585 amino acid residues with a relative molecular mass of 66.438 kD.It is synthesized by the liver at a rate of approximately 200 mg·kg^(-1)·day^(-1),with a half-life of 21 days,and subjected to catabolism in the muscles,liver,and kidneys at a rate of 4%per day.[1]Albumin,accounting for 60%of the total plasma protein,has various physiological functions,[2]such as maintaining 70%to 80%of effective plasma colloid osmotic pressure,coordinating vascular endothelial integrity,anti-oxidant and anti-inflammatory activities,maintaining the acidbase balance,and participating in the transport,distribution,and metabolism of a variety of endogenous and exogenous substances. | Yue-Tian Yu Jiao Liu Bo Hu Rui-Lan Wang Xiang-Hong Yang Xiu-Ling Shang Gang Wang Chang-Song Wang Bai-Ling Li Ye Gong Sheng Zhang Xin Li Lu Wang Min Shao Mei Meng Feng Zhu You Shang Qiang-Hong Xu Zhi-Xiong Wu De-Chang Chen | 2021 | Chinese Medical Journal2021，，14： | 22 |
| 2 | Experimental investigation of the generation of large-amplitude internal solitary wave and its interaction with a submerged slender body显示文摘A principle of generating the nonlinear large-amplitude internal wave in a stratified fluid tank with large cross-section is proposed according to the‘jalousie’control mode.A new wave-maker based on the principle was manufactured and the experiments on the generation and evolution of internal solitary wave were conducted.Both the validity of the new device and applicability range of the KdV-type internal soliton theory were tested.Furthermore,a measurement technique of hydrodynamic load of internal waves was developed.By means of accurately measuring slight variations of internal wave forces exerted on a slender body in the tank,their interaction characteristics were determined.It is shown that through establishing the similarity between the model scale in the stratified fluid tank and the full scale in the numerical simulation the obtained measurement results of internal wave forces are confirmed to be correct. | WEI Gang DU Hui XU XiaoHui ZHANG YuanMing QU ZiYun HU TianQun YOU YunXiang | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，2： | 17 |
| 3 | Effects of warming and clipping on plant and soil properties of an alpine meadow in the Qinghai-Tibetan Plateau, China显示文摘Climate warming and livestock grazing are known to have great influences on alpine ecosystems like those of the Qinghai-Tibetan Plateau(QTP) in China. However, it is lacking of studies on the effects of warming and grazing on plant and soil properties in these alpine ecosystems. In this study, we reported the related research from manipulative experiment in 2010–2012 in the QTP. The aim of this study was to investigate the individual and combined effects of warming and clipping on plant and soil properties in the alpine meadow ecosystem. Infrared radiators were used to simulate climate warming starting in July 2010, while clipping was performed once in October 2011 to simulate the local livestock grazing. The experiment was designed as a randomized block consisting of five replications and four treatments: control(CK), warming(W), clipping(C) and warming+clipping combination(WC). The plant and soil properties were investigated in the growing season of the alpine meadow in 2012. The results showed that W and WC treatments significantly decreased relative humidity at 20-cm height above ground as well as significantly increases air temperature at the same height, surface temperature, and soil temperature at the depth of 0–30 cm. However, the C treatment did not significantly decrease soil moisture and soil temperature at the depth of 0–60 cm. Relative to CK, vegetation height and species number increased significantly in W and WC treatment, respectively, while vegetation aboveground biomass decreased significantly in C treatment in the early growing season. However, vegetation cover, species diversity, belowground biomass and soil properties at the depth of 0–30 cm did not differ significantly in W, C and WC treatments. Soil moisture increased at the depth of 40–100 cm in W and WC treatments, while belowground biomass, soil activated carbon, organic carbon and total nitrogen increased in the 30–50 cm soil layer in W, C and WC treatments. Although the initial responses of plant and soil properties to experimental warming and clipping were slow and weak, the drought induced by the downward shift of soil moisture in the upper soil layers may induce plant belowground biomass to transfer to the deeper soil layers. This movement would modify the distributions of soil activated carbon, organic carbon and total nitrogen. However, long-term data collection is needed to further explain this interesting phenomenon. | Man Hou XU Fei PENG Quan Gang YOU Jian GUO Xia Fei TIAN Min LIU Xian XUE | 2015 | Journal of Arid Land2015，7，2： | 14 |
| 4 | Hierarchical Magnetic Network Constructed by CoFe Nanoparticles Suspended Within “Tubes on Rods” Matrix Toward Enhanced Microwave Absorption显示文摘Hierarchical magnetic-dielectric composites are promising functional materials with prospective applications in microwave absorption(MA)field.Herein,a three-dimension hierarchical“nanotubes on microrods,”core–shell magnetic metal–carbon composite is rationally constructed for the first time via a fast metal–organic frameworksbased ligand exchange strategy followed by a carbonization treatment with melamine.Abundant magnetic CoFe nanoparticles are embedded within one-dimensional graphitized carbon/carbon nanotubes supported on micro-scale Mo2N rod(Mo2N@CoFe@C/CNT),constructing a special multi-dimension hierarchical MA material.Ligand exchange reaction is found to determine the formation of hierarchical magnetic-dielectric composite,which is assembled by dielectric Mo2N as core and spatially dispersed CoFe nanoparticles within C/CNTs as shell.Mo2N@CoFe@C/CNT composites exhibit superior MA performance with maximum reflection loss of−53.5 dB at 2 mm thickness and show a broad effective absorption bandwidth of 5.0 GHz.The Mo2N@CoFe@C/CNT composites hold the following advantages:(1)hierarchical core–shell structure offers plentiful of heterojunction interfaces and triggers interfacial polarization,(2)unique electronic migration/hop paths in the graphitized C/CNTs and Mo2N rod facilitate conductive loss,(3)highly dispersed magnetic CoFe nanoparticles within“tubes on rods”matrix build multi-scale magnetic coupling network and reinforce magnetic response capability,confirmed by the off-axis electron holography. | Chunyang Xu Lei Wang Xiao Li Xiang Qian Zhengchen Wu Wenbin You Ke Pei Gang Qin Qingwen Zeng Ziqi Yang Chen Jin Renchao Che | 2021 | Nano-Micro Letters2021，13，3： | 10 |
| 5 | Effect of temperature on the sorption and desorption of perfluorooctane sulfonate on humic acid显示文摘Sorption and desorption of perfluorooctane sulfonate (PFOS) on humic acid at different temperatures were studied. It was found that the sorption process could be modeled with power kinetic equation very well, suggesting that diflusion predominated the sorption of PFOS on the humic acid. The sorption capacity was doubled when the temperature increased from 5 to 35°C, and thermodynamics parameters △G0 was calculated to be -7.11 to -5.04 kJ/mol, △H0 was 14.2 kJ/mol, and △S 0 was 69.5 J/(mol·K), indicating that the sorption was a spontaneous, endothermic, and entropy driven process. Desorption hysteresis occurred at all studied temperatures which suggested that humic acid may be an important sink of PFOS in the environment. | Chengxia Jia, Chun You, Gang Pan State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. | 2010 | Journal of Environmental Sciences2010，22，3： | 10 |
| 6 | Effect of Dietary Supplementation with Hydrolyzed Wheat Gluten on Growth Performance, Cell Immunity and Serum Biochemical Indices of Weaned Piglets (Sus scrofa)显示文摘To investigate the effects of dietary supplementation with hydrolyzed wheat gluten (HWG) on growth performance, cell immunity and serum biochemical indices of weaned piglets, 160 crossed (Large White×andrace) and weaned piglets were randomly divided into 4 treatments with 4 replicates of 10 piglets each. The piglets in each treatment were fed an experimental diet containing either 0 g kg-1 HWG (control group), 30 g kg-1 HWG (3% HWG group), 50 g kg-1 HWG (5% HWG group), or 2.5 g kg-1 glycyl-L-glutamine (0.25% Gly-Gln group). The results showed that the diarrhea rates in 3% HWG and 5% HWG groups were significantly lower than in control group from d 1 to 14 (P<0.05), while the average daily gain (ADG) in each of two groups was increased (P>0.05). When compared with control group, dietary supplementation with 3% HWG increased the ratio of CD4+:CD8+ and the ratio of serum albumin and globulin concentrations (A:G) on d 14 and 28, as well as the proliferation of T- and B-lymphocytes (P>0.05) on d 28. In addition, on d 14 and 28, the A:G ratio in 5% HWG group was significantly higher than in control group (P<0.05), while the ratio of CD4+:CD8+ increased slightly (P>0.05). Interestingly, 0.25% Gly-Gln group had higher proportion of CD3+ (P>0.05) and CD4+ (P<0.05) on d 14 than control group, but growth performances of 0.25% Gly-Gln group were negatively affected at all experiment stages. These results suggested that HWG might improve the growth performance of piglets by strengthening cell immunity and decreasing the occurrence of diarrhea during the prophase after weaning. | WANG Xiu-qi FENG You SHU Gang JIANG Qing-yan YANG Jing-pei ZHANG Zi-feng | 2011 | Agricultural Sciences in China2011，10，6： | 6 |
| 7 | Role of intestinal flora imbalance in pathogenesis of pouchitis显示文摘Objective: To discuss the role of intestinal flora imbalance in the pathogenesis of pouchitis. Methods: The puochitis rat model was established and the faeces sample and the mucous membrane sample were collected regularly, in which the bacterial nucleic acids were extracted for quantitative analysis of the intestinal flora in the samples through using the real-time quantitative PCR technique and high energy sequencing technology. Results: The disorder phenomenon of the intestinal flora appeared at the 7th day of the experiment, and the pouchitis was presented at the 21 th day of the experiment. At the 31 th day of the experiment, compared to control group and non-pouchitis group, the quantity of Bifidobacterium and the Lactobacillusof the pouchitis model rats in the mucous membrane sample and the faeces sample were significantly decreased(P<0.05), and the Bacteroidetes, Faecalibacterium prausnitzii and 桛 Clostridium leptum subgroup in the mucous membrane of pouchitis were significantly decreased(P<0.05). The Clostridium coccoides group was the main flora in the mucous membrane of pouchitis, the bacterial diversity of non-puochitis group and control group was significantly higher than that of the puochitis group(P<0.05). Conclusions: The intestinal flora imbalance is one of the factors that cause the incidence of the pouhitis; this study provides a clue of the pathogenesis and treatment direction of the intestinal inflammatory disease. | Xiao-Bo Feng Jun Jiang Min Li Gang Wang Jin-Wei You Jian Zuo | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，8： | 5 |
| 8 | Unraveling a genetic roadmap for improved taste in the domesticated apple显示文摘Although taste is an important aspect of fruit quality, an understanding of its genetic control remains elusive in apple and other fruit crops. In this study, we conducted genomic sequence analysis of 497 Malus accessions and revealed erosion of genetic diversity caused by apple breeding and possible independent domestication events of dessert and cider apples. Signatures of selection for fruit acidity and size, but not for fruit sugar content, were detected during the processes of both domestication and improvement. Furthermore, we found that single mutations in major genes affecting fruit taste, including Ma1, MdTDT, and MdSOT2, dramatically decrease malate, citrate, and sorbitol accumulation, respectively, and correspond to important domestication events. Interestingly, Ma1 was identified to have pleiotropic effects on both organic acid content and sugar:acid ratio, suggesting that it plays a vital role in determining fruit taste. Fruit taste is unlikely to have been negatively affected by linkage drag associated with selection for larger fruit that resulted from the pyramiding of multiple genes with minor effects on fruit size. Collectively, our study provides new insights into the genetic basis of fruit quality and its evolutionary roadmap during apple domestication, pinpointing several candidate genes for genetic manipulation of fruit taste in apple. | Liao Liao Weihan Zhang Bo Zhang Ting Fang Xiao-Fei Wang Yarning Cai Collins Ogutu Lei Gao Gang Chen Xiaoqing Nie Jinsheng Xu Quanyan Zhang Yiran Ren Jianqiang Yu Chukun Wang Cecilia H.Deng Baiquan Ma Beibei Zheng Chun-Xiang You Da-Gang Hu Richard Espley Kui Lin-Wang Jia-Long Yao Andrew C.Allan Awais Khan Schuyler S.Korban Zhangjun Fei Ray Ming Yu-Jin Hao Li Li Yuepeng Han | 2021 | Molecular Plant2021，14，9： | 5 |
| 9 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 10 | Combined Effect of Smoking and Obesity on Coronary Heart Disease Mortality in Male Veterans:A 30-year Cohort Study显示文摘Objective Evidence is lacking regarding the combined effects of smoking and obesity on mortality from coronary heart disease in male veterans.This study aimed to explore the combined effect of smoking and obesity on coronary heart disease mortality in male veterans in China.Methods A cohort of 1,268 male veterans from 22 veteran centers in Xi’an(Shaanxi Province,China)were followed up once every 2 years from February 1,1987 to October 30,2016.The endpoint was death from any cause.The hazard ratio(HR)of each risk factor and the 95%confidence interval(CI)were calculated using a multivariate Cox proportional hazard model.Results The total follow-up was 24394.21 person-years;each subject was followed up for a mean duration of 19.24 years.By the end of the study,of the 1,268 veterans,889 had died,363 were alive,and 16 were lost to follow-up.Cox regression analysis results revealed that current smoking(HR:1.552,95%CI:1.074–2.243),obesity(HR:1.625,95%CI:1.024–2.581),and the combined effect of the two factors(HR:2.828,95%CI:1.520–5.262)were associated with coronary heart disease mortality.Conclusion Our results suggest that obese veterans who smoke might be an important target population for coronary heart disease mortality control. | SAI Xiao Yong GAO Feng ZHANG Wen Yu GAO Meng YOU Jing SONG Yu Jian LUO Ting Gang SUN Yuan Yuan | 2021 | Biomedical and Environmental Sciences2021，34，3： | 5 |
| 11 | The role of histone methylation in the development of digestive cancers:a potential direction for cancer management显示文摘Digestive cancers are the leading cause of cancer-related death worldwide and have high risks of morbidity and mortality.Histone methylation,which is mediated mainly by lysine methyltransferases,lysine demethylases,and protein arginine methyltransferases,has emerged as an essential mechanism regulating pathological processes in digestive cancers.Under certain conditions,aberrant expression of these modifiers leads to abnormal histone methylation or demethylation in the corresponding cancer-related genes,which contributes to different processes and phenotypes,such as carcinogenesis,proliferation,metabolic reprogramming,epithelial–mesenchymal transition,invasion,and migration,during digestive cancer development.In this review,we focus on the association between histone methylation regulation and the development of digestive cancers,including gastric cancer,liver cancer,pancreatic cancer,and colorectal cancer,as well as on its clinical application prospects,aiming to provide a new perspective on the management of digestive cancers. | Yuan Chen Bo Ren Jinshou Yang Huanyu Wang Gang Yang Ruiyuan Xu Lei You Yupei Zhao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 12 | Regional Meteorological Patterns for Heavy Pollution Events in Beijing显示文摘The present study investigates meteorological conditions for the day-to-day changes of particulate matter(PM)concentration in Beijing city during the period 2008–2015. The local relationship of PM concentration to surface air temperature, pressure, wind speed, and relative humidity displays seasonal changes and year-to-year variations. The average correlation coefficient with PM10 in spring, summer, fall, and winter is 0.45, 0.40, 0.38, and 0.30 for air temperature; –0.45, –0.05, –0.40, and –0.45 for pressure; 0.13, 0.04, 0.53, and 0.50 for relative humidity; and –0.18,–0.11, –0.45, and –0.33 for wind speed. A higher correlation with wind speed is obtained when wind speed leads by half a day. The heavily polluted and clean days, which are defined as the top and bottom 10% of the PM values, show obvious differences in the regional distribution of air temperature, pressure, and wind. Polluted days correspond to higher air temperature in all the four seasons, lower sea level pressure and anomalous southerly winds to the south and east of Beijing in spring, fall, and winter, and a northwest–southeast contrast in the pressure anomaly and anomalous southerly winds in summer. Higher relative humidity is observed on polluted days in fall and winter. The polluted days are preceded by an anomalous cyclone moving from the northwest, accompanied by lower pressure and higher air temperature, in all four seasons. This feature indicates the impacts of moving weather systems on local meteorological conditions for day-to-day air quality changes in Beijing. | ting you renguang wu gang huang guangzhou fan | 2017 | Journal of Meteorological Research2017，31，3： | 4 |
| 13 | MiR-135a biogenesis and regulation in malignancy:a new hope for cancer research and therapy显示文摘MicroRNAs(miRNAs)are evolutionarily conserved small non-coding RNAs that affect posttranscriptional regulation by binding to the 3′-untranslated region of target messenger RNAs.MiR-135a is a critical miRNA that regulates gene expression,and many studies have focused on its function in cancer research.MiR-135a is dysregulated in various cancers and regulates cancer cell proliferation and invasionvia several signaling pathways,such as the MAPK and JAK2/STAT3 pathways.MiR-135a has also been found to promote or inhibit the epithelial-mesenchymal transition and chemoresistance in different cancers.Several studies have discovered the value of miR-135a as a novel biomarker for cancer diagnosis and prognosis.These studies have suggested the potential of therapeutically manipulating miR-135a to improve the outcome of cancer patients.Although these findings have demonstrated the role of miR-135a in cancer progression and clinical applications,a number of questions remain to be answered,such as the dual functional roles of miR-135a in cancer.In this review,we summarize the available studies regarding miR-135a and cancer,including background on the biogenesis and expression of miR-135a in cancer and relevant signaling pathways involved in miR-135a-mediated tumor progression.We also focus on the clinical application of miR-135a as a biomarker in diagnosis and as a therapeutic agent or target in cancer treatment,which will provide a greater level of insight into the translational value of miR-135a. | Zhe Cao Jiangdong Qiu Gang Yang Yueze Liu Wenhao Luo Lei You Lianfang Zheng Taiping Zhang | 2020 | Cancer Biology & Medicine2020，17，3： | 4 |
| 14 | An innovative study on low surface energy micronano coatings with multilevel structures for laminar flow design显示文摘Laminar flow design is one of the most effective ways to reduce the drag of a commercial aircraft by expanding the laminar flow region on the surface of the aircraft. As material science develops, the emergence of new materials such as low surface energy materials has offered new choices for laminar flow design of commercial aircraft. Different types of low surface energy micro-nano coatings are prepared to verify the effects on the boundary layer transition position and the drag of the airfoil through wind tunnel tests. The infrared thermal imaging technology is adopted for measuring the boundary layer transition, while the momentum integral approach is employed to measure the drag coefficient through a wake rake. Infrared thermal imaging results indicate that the coatings are capable of moving backward the boundary layer transition position at both a low velocity of Mach number 0.15 and a high velocity of Mach number 0.785. Results of the momentum integral approach demonstrate that the drag coefficients are reduced obviously within the cruising angle of attack range from 1° and 5° by introducing the low surface energy micro-nano coating technology. | Jun TAO Gang SUN Gang WU Liqiang GUO Yongjian ZHONG Meng WANG Bo YOU | 2019 | Chinese Journal of Aeronautics2019，32，3： | 3 |
| 15 | UNSTEADY INTERFACIAL WAVES DUE TO SINGULARITIES IN TWO SEMI-INFINITE INVISCID FLUIDS显示文摘The generation of unsteady interfacial gravity waves by a singularity immersed in two semi-infinite fluids was analytically investigated in detail by the methods of integral transform and of stationary-phase analysis. The fluids were assumed to be initially stationary, immiscible, inviscid and incompressible. The disturbed flows, generated by an impulsive and oscillatory source/dipole immersed above or beneath the interface, were governed by the Laplace equations. The kinematic and dynamic boundary conditions on the interface were linearized for the small-amplitude waves. By means of the stationary-phase analysis on the exact integral-form solutions, the asymptotic representations for the interfacial waves were derived for large time with a fixed distance-to-time ratio. The relation between a submerged singularity and a surface pressure point was discussed. It is found that the local wavelength and the local wave period of the interfacial waves are elongated in comparison with those of free-surface waves for a single fluid. | LU Dong-qiang WEI Gang YOU Yun-xiang | 2005 | Journal of Hydrodynamics2005，17，6： | 3 |
| 16 | Application of Keyhole Microneurosurgery in China显示文摘 | Li-Gang Chen Shu-Da Chen Guang-Fu Huang Ying Huang De-Zhi Kang Qing Lan Gang Li Xin-Gang Li Zhi-Xiong Liu Song-Tao Qi Xin-Hua Tian Guo-Liang Wang Shuo Wang Xiang-Yu Wang Yong-Fei Wang Yun-Jie Wang Chao You Yan-Bing Yu Shu-Yuan Yue Dong Zhang Jian-Min Zhang Jian-Ning Zhang Jun-Ting Zhang Shi-Zhong Zhang Xian Zhang Ya-Zhuo Zhang Ji-Zong Zhao Wei-Guo Zhao Yuan-Li Zhao Ding-Biao Zhou Liang-Fu Zhou | 2017 | Chinese Medical Journal2017，，16： | 3 |
| 17 | Regional changes in extreme heat events in China under stabilized 1.5℃ and 2.0℃ global warming显示文摘Extreme heat events(EHEs)have a significant impact on the social economy and human health.China is a country with a large population and diverse terrain,and it is necessary to project future extreme heat changes in the sub-regions.This study used a specially designed dataset,the Community Earth System Model(CESM)simulations,namely CESM low-warming,to investigate the EHEs in China under 1.5℃ and 2.0℃ global warming.The results indicate that the regional mean warming over China will exceed the global average,about 1.63℃ and 2.24℃ in 1.5℃ and 2.0℃ warmer futures.Compared to the present-day(1976–2005),the frequency and duration of the EHEs in South China are projected to increase the most among the sub-regions.For example,the frequency of EHEs in South China at 1.5℃ and 2.0℃ warming will exceed 3 and 3.5 times the present-day level.However,when global warming rises from 1.5℃ to 2.0℃,the increased impacts relative to the 1.5℃ warming level will be the lowest in South China(less than 40%),and the highest increased impacts are projected to appear in Northeast China(53%-84%)and Northwest China(53%–107%).The main reason for this situation is that compared with the 1.5℃ scenario,the upper zonal westerly in northern China weakens and the continental high pressure enhances under the 2.0℃ scenario.Therefore,limiting global warming at 1.5℃ instead of 2.0℃ is beneficial for eliminating extreme heat events,especially for Northeast China and Northwest China. | ZHANG Gu-Wei ZENG Gang Vedaste IYAKAREMYE YOU Qing-Long | 2020 | Advances in Climate Change Research2020，11，3： | 3 |
| 18 | Relationship between magnetic resonance imaging and molecular pathology in patients with glioblastoma multiforme显示文摘背景 Glioblastoma multiforme ( GBM )是在 adults.Magnetic 回声成像( MRI )的最普通、致命的主要大脑肿瘤习惯性地在诊断被使用,描述和 GBM.The 诊断的临床的管理和 GBM 的治疗被试图识别在磁性的回声特征和 43 个 glioblastoma 病人的 GBM.Methods MRI 图象的分子的病理之间的关系的组织病理学说和 immunohistochemistry.This 学习大部分指导是 collected.Four 成像特征, | LI Wen-bin TANG Kai ZHANG Wei YAN Wei YOU Gang LI Shao-wu ZHANG Long HUANG Yan-jie JIANG Tao | 2011 | Chinese Medical Journal2011，，17： | 3 |
| 19 | Urinary analysis reveals high Alternaria mycotoxins exposure in the general population from Beijing, China显示文摘Alternaria mycotoxins are of concern due to its adverse health effect, they affect various cereal crops and grain-based food along with modified forms that contribute to overall exposure. This study aimed to determine the frequency and level of exposure to Alternaria mycotoxins(tenuazonic acid, TeA;alternariol, AOH;alternariol monomethyl ether, AME;tentoxin, TEN;and altenuene, ALT) in human urine from Beijing adults. A total of 2212 urine samples were collected and analyzed for five mycotoxins using LC–ESI–MS/MS. More than98% of the samples had at least one Alternaria mycotoxin detected. Among the mycotoxins,AME had the highest detection rate(96.0%), followed by TeA(70.5%). The calculated average daily intake values of AME(12.5 ng/kg b.w.) was 5 times the TTC value(2.5 ng/kg b.w.) set by the EFSA, indicating the potential health risks associated with mycotoxins. Immediate attention and subsequent actions should be taken to identify the sources of mycotoxins and the corresponding exposure pathways to humans in the investigated regions. | Xiaoting Qiao Gang Li Jing Zhang Jing Du Yunjia Yang Jie Yin Hui Li Jie Xie You Jiang Xiang Fang Xinhua Dai Bing Shao | 2022 | Journal of Environmental Sciences2022，34，8： | 3 |
| 20 | Thermotolerant and fireproof gel polymer electrolyte toward high-performance and safe lithium-ion battery显示文摘Poly(ethylene oxide)(PEO)and its derivatives based gel polymer electrolytes(GPEs)are severely limited in advanced and safe lithium-ion batteries(LIBs)owing to the intrinsically high flammability of liquid electrolytes and PEO.Directly adding flame retardants to the GPEs can suppress their flammability and thus improve the safety of LIBs,but results in deteriorative electrochemical performance.Herein,a novel GPE with chemically bonded flame retardant(i.e.diethyl vinylphosphonate)in cross-linked polyethylene glycol diacrylate matrix,featuring both high-safety and high-performance,is designed.This as-prepared GPE storing the commercial 1 mol L^(-1) LiPF6 electrolyte resists high temperature of 200℃and cannot be ignited as well as possesses a high ionic conductivity(0.60 m S cm^(-1))and good compatibility with lithium.Notably,the LiFePO_(4)/Li battery with this GPE delivers a satisfactory capacity of 142.2 m A h g^(-1) and a superior cycling performance with a capacity retention of 96.3%and a coulombic efficiency of close to 100%for 350 cycles at 0.2 C under ambient temperature.Furthermore,the battery can achieve steady charge–discharge for 100 cycles with a coulombic efficiency of 99.5%at 1 C under 80℃and run normally even at a high temperature of 150℃or under the exposure to butane flame.Differential scanning calorimetry manifests significantly improved battery safety compared to commercial battery systems.This work provides a new pathway for developing next-generation advanced LIBs with enhanced performance and high safety. | Man-Cheng Long Ting Wang Ping-Hui Duan You Gao Xiu-Li Wang Gang Wu Yu-Zhong Wang | 2022 | Journal of Energy Chemistry2022，31，2： | 3 |
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